The Association between Exposure to Fine Particulate Matter and MRI-Assessed Locus Coeruleus Integrity in the Vietnam Era Twin Study of Aging (VETSA).

Authors: Puckett, Olivia K.^1,2, Fennema-Notestine, Christine^1,2,3, Hagler Jr., Donald J.³, Braskie, Meredith N.⁴, Jiu-Chiuan Chen^5,6, Finch, Caleb E.⁷, Kaufman, Joel D.^8,9,10, Petkus, Andrew J.⁶, Reynolds, Chandra A.^11,12, Salminen, Lauren E.⁴, Thompson, Paul M.⁴, Xinhui Wang⁶, Kremen, William S.^1,2, Franz, Carol E.^1,2, Elman, Jeremy A.^1,2, jaelman@health.ucsd.edu

Source: Environmental Health Perspectives; Jul2024, Vol. 132 Issue 7, p077006-1-077006-8, 8p

Air pollution nanoparticle and alpha-synuclein fibrils synergistically decrease glutamate receptor A1, depending upon nPM batch activity

Authors: Zhang, Hongqiao ^{a, ∗}, D'Agostino, Carla ^a, Tulisiak, Christopher ^{b, 1}, Thorwald, Max A. ^a, Bergkvist, Liza ^b, Lindquist, Allison ^b, Meyerdirk, Lindsay ^b, Schulz, Emily ^b, Becker, Katelyn ^b, Steiner, Jennifer A. ^b, Cacciottolo, Mafalda ^{a, 2}, Kwatra, Mohit ^b, Rey, Nolwen L. ^{b, 3}, Escobar Galvis, Martha L. ^b, Ma, Jiyan ^{b, 4}, Sioutas, Constantinos ^c, Morgan, Todd E. ^a, Finch, Caleb E. ^a, Brundin, Patrik ^{b, 5}

Source: In Heliyon April 2023 9(4)

Age, sex, and cerebral microbleeds in EFAD Alzheimer disease mice

Authors: Cacciottolo, Mafalda, Morgan, Todd E., Finch, Caleb E.

Source: In Neurobiology of Aging July 2021 103:42-51

Iron chelation by oral deferoxamine treatment decreased brain iron and iron signaling proteins.

Authors: Thorwald, Max A, Sta Maria, Naomi S, Chakhoyan, Ararat, O'Day, Peggy A, Jacobs, Russell E, Zlokovic, Berislav, Finch, Caleb E

Source: Journal of Alzheimer's Disease; Feb2025, Vol. 103 Issue 4, p1180-1190, 11p

Subject Terms: PROTEIN precursors, ALZHEIMER'S disease, IRON proteins, MAGNETIC resonance imaging, IRON chelates

Iron‐associated lipid peroxidation in Alzheimer's disease is increased in lipid rafts with decreased ferroptosis suppressors, tested by chelation in mice.

Authors: Thorwald, Max A., Godoy‐Lugo, Jose A., Garcia, Gilberto, Silva, Justine, Kim, Minhoo, Christensen, Amy, Mack, Wendy J., Head, Elizabeth, O'Day, Peggy A., Benayoun, Bérénice A., Morgan, Todd E., Pike, Christian J., Higuchi‐Sanabria, Ryo, Forman, Henry Jay, Finch, Caleb E.

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Jan2025, Vol. 21 Issue 1, p1-26, 26p

THE EXPOSOME IN HUMAN EVOLUTION : FROM DUST TO DIESEL

Authors: Trumble, Benjamin C., Finch, Caleb E.

Source: The Quarterly Review of Biology, 2019 Dec 01. 94(4), 333-394.

Access URL: https://www.jstor.org/stable/26862651

Lifespan Fluidity and Its Biological Limitations in Socio‐Economic Health Differences.

Authors: Finch, Caleb E.¹ (AUTHOR) cefinch@usc.edu, Jylhä, Marja K.² (AUTHOR)

Source: Journal of the American Geriatrics Society. Apr2025, p1. 3p. 1 Illustration.

Subject Terms: *MEDICAL sciences, *HUMAN biology, *PHYSICAL mobility, *ARYL hydrocarbon receptors, *AIR pollutants, *MOBILITY of older people, *OLDER men

Toxicity of urban air pollution particulate matter in developing and adult mouse brain: Comparison of total and filter-eluted nanoparticles

Authors: Haghani, Amin, Johnson, Richard, Safi, Nikoo, Zhang, Hongqiao, Thorwald, Max, Mousavi, Amirhosein, Woodward, Nicholas C., Shirmohammadi, Farimah, Coussa, Valerio, Wise, John P., Jr, Forman, Henry Jay, Sioutas, Constantinos, Allayee, Hooman, Morgan, Todd E., Finch, Caleb E.

Source: In Environment International March 2020 136

Traffic-related air pollutants (TRAP-PM) promote neuronal amyloidogenesis through oxidative damage to lipid rafts

Authors: Cacciottolo, Mafalda, Morgan, Todd E., Saffari, Arian A., Shirmohammadi, Farimah, Forman, Henry Jay, Sioutas, Costantinos, Finch, Caleb E.

Source: In Free Radical Biology and Medicine 1 February 2020 147:242-251

Cell-based assays that predict in vivo neurotoxicity of urban ambient nano-sized particulate matter

Authors: Zhang, Hongqiao, Haghani, Amin, Mousavi, Amirhosein H., Cacciottolo, Mafalda, D'Agostino, Carla, Safi, Nikoo, Sowlat, Mohammad H., Sioutas, Constantinos, Morgan, Todd E., Finch, Caleb E., Forman, Henry Jay

Source: In Free Radical Biology and Medicine December 2019 145:33-41

The Alzheimer's Disease Exposome

Authors: Finch, Caleb E., Kulminski, Alexander M.

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association September 2019 15(9):1123-1132

Air pollution amyloidogenesis is attenuated by the gamma‐secretase modulator GSM‐15606.

Authors: Godoy‐Lugo, Jose A., Thorwald, Max A., Cacciottolo, Mafalda, D'Agostino, Carla, Chakhoyan, Ararat, Sioutas, Constantinos, Tanzi, Rudolph E., Rynearson, Kevin D., Finch, Caleb E.

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Sep2024, Vol. 20 Issue 9, p6107-6114, 8p

Vascular dysfunction—The disregarded partner of Alzheimer's disease

Authors: Sweeney, Melanie D., Montagne, Axel, Sagare, Abhay P., Nation, Daniel A., Schneider, Lon S., Chui, Helena C., Harrington, Michael G., Pa, Judy, Law, Meng, Wang, Danny J.J., Jacobs, Russell E., Doubal, Fergus N., Ramirez, Joel, Black, Sandra E., Nedergaard, Maiken, Benveniste, Helene, Dichgans, Martin, Iadecola, Costantino, Love, Seth, Bath, Philip M., Markus, Hugh S., Salman, Rustam A., Allan, Stuart M., Quinn, Terence J., Kalaria, Rajesh N., Werring, David J., Carare, Roxana O., Touyz, Rhian M., Williams, Steve C.R., Moskowitz, Michael A., Katusic, Zvonimir S., Lutz, Sarah E., Lazarov, Orly, Minshall, Richard D., Rehman, Jalees, Davis, Thomas P., Wellington, Cheryl L., González, Hector M., Yuan, Chun, Lockhart, Samuel N., Hughes, Timothy M., Chen, Christopher L.H., Sachdev, Perminder, O'Brien, John T., Skoog, Ingmar, Pantoni, Leonardo, Gustafson, Deborah R., Biessels, Geert Jan, Wallin, Anders, Smith, Eric E., Mok, Vincent, Wong, Adrian, Passmore, Peter, Barkof, Frederick, Muller, Majon, Breteler, Monique M.B., Román, Gustavo C., Hamel, Edith, Seshadri, Sudha, Gottesman, Rebecca F., van Buchem, Mark A., Arvanitakis, Zoe, Schneider, Julie A., Drewes, Lester R., Hachinski, Vladimir, Finch, Caleb E., Toga, Arthur W., Wardlaw, Joanna M., Zlokovic, Berislav V.

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association January 2019 15(1):158-167

Is coronary calcium scoring too late? Total body arterial calcium burden in patients without known CAD and normal MPI

Authors: Allam, Adel H.A., Thompson, Randall C., Eskander, Michael A. ^*, Mandour Ali, Mohamed A., Sadek, Ayman, Rowan, Chris J., Sutherland, M. Linda, Sutherland, James D., Frohlich, Bruno, Michalik, David E., Finch, Caleb E., Narula, Jagat, Thomas, Gregory S., Samuel Wann, L.

Source: In Journal of Nuclear Cardiology December 2018 25(6):1990-1998

Aging attenuates redox adaptive homeostasis and proteostasis in female mice exposed to traffic-derived nanoparticles (‘vehicular smog’)

Authors: Pomatto, Laura C.D., Cline, Mayme, Woodward, Nicholas, Pakbin, Payam, Sioutas, Constantinos, Morgan, Todd E., Finch, Caleb E., Forman, Henry Jay, Davies, Kelvin J.A.

Source: In Free Radical Biology and Medicine June 2018 121:86-97

Inflammatory Exposure and Historical Changes in Human Life-Spans

Authors: Finch, Caleb E., Crimmins, Eileen M.

Source: Science, 2004 Sep . 305(5691), 1736-1739.

Access URL: https://www.jstor.org/stable/3837759

Alzheimer's Disease-Affected Brain: Presence of Oligomeric Aβ Ligands (ADDLs) Suggests a Molecular Basis for Reversible Memory Loss

Authors: Gong, Yuesong, Chang, Lei, Viola, Kirsten L., Lacor, Pascale N., Lambert, Mary P., Finch, Caleb E., Krafft, Grant A., Klein, William L.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Sep 01. 100(18), 10417-10422.

Access URL: https://www.jstor.org/stable/3147731

Evolutionary Medicine: From Dwarf Model Systems to Healthy Centenarians?

Authors: Longo, Valter D., Finch, Caleb E.

Source: Science, 2003 Feb . 299(5611), 1342-1346.

Access URL: https://www.jstor.org/stable/3833491

Inhaled Pollutants of the Gero-Exposome and Later-Life Health.

Authors: Finch, Caleb E¹ (AUTHOR), Thorwald, Max A¹ (AUTHOR) thorwald@usc.edu

Source: Journals of Gerontology Series A: Biological Sciences & Medical Sciences. Jul2024, Vol. 79 Issue 7, p1-9. 9p.

Subject Terms: *AIR pollutants, *POLLUTANTS, *CIGARETTE smoke, *ALZHEIMER'S disease, *FETAL development

Atherosclerosis in ancient mummified humans: the global HORUS study.

Authors: Thompson, Randall C, Sutherland, M Linda, Allam, Adel H, Paladin, Alice, Zink, Albert R, Wann, L Samuel, Sutherland, James D, Frohlich, Bruno, Hunt, David, Miyamoto, Michael I, Rowan, Christopher J, Michalik, David E, Finch, Caleb E, Lombardi, Guido P, Soliman, Muhammad Al-Tohamy, Monge, Janet M, Vallodolid, Clide M, Cox, Samantha L, Abdel-Maksoud, Gomaa, Badr, Ibrahim

Source: European Heart Journal; 7/1/2024, Vol. 45 Issue 25, p2259-2262, 4p

Subject Terms: ATHEROSCLEROSIS, CORONARY artery calcification, ARTERIAL calcification, ATHEROSCLEROTIC plaque