Ring expansion of 5- to 6-member zirconacycles by carbenoid insertion

Authors: Dixon, Sally, Fillery, Shaun M., Kasatkin, Aleksandra, Norton, David, Thomas, Emma, Whitby, Richard J. ^∗

Source: In Tetrahedron 2004 60(6):1401-1416

Discovery of a Potent and Selective ATAD2 Bromodomain Inhibitor with Antiproliferative Activity in Breast Cancer Models.

Authors: Winter-Holt, Jon J., Bardelle, Catherine, Chiarparin, Elisabetta, Dale, Ian L., Davey, Paul R. J., Davies, Nichola L., Denz, Christopher, Fillery, Shaun M., Guérot, Carine M., Fujin Han, Hughes, Samantha J., Kulkarni, Meghana, Zhaoqun Liu, Milbradt, Alexander, Moss, Thomas A., Huijun Niu, Patel, Joe, Rabow, Alfred A., Schimpl, Marianne, Junjie Shi

Source: Journal of Medicinal Chemistry; 2/24/2022, Vol. 65 Issue 4, p3306-3331, 26p

Diverse, Potent, and Efficacious Inhibitors That Target the EED Subunit of the Polycomb Repressive Complex 2 Methyltransferase.

Authors: Bagal, Sharan K., Gregson, Clare, O' Donovan, Daniel H., Pike, Kurt G., Bloecher, Andrew, Barton, Peter, Borodovsky, Alexandra, Code, Erin, Fillery, Shaun M., Hsu, Jessie Hao-Ru, Kawatkar, Sameer P., Li, Chengzhi, Longmire, David, Nai, Youfeng, Nash, Samuel C., Pike, Andrew, Robinson, James, Read, Jon A., Rawlins, Phillip B., Shen, Minhui

Source: Journal of Medicinal Chemistry; 12/9/2021, Vol. 64 Issue 23, p17146-17183, 38p

A Buchwald–Hartwig Protocol to Enable Rapid Linker Exploration of Cereblon E3‐Ligase PROTACs**.

Authors: Hayhow, Thomas G., Borrows, Rachel E. A., Diène, Coura R., Fairley, Gary, Fallan, Charlene, Fillery, Shaun M., Scott, James S., Watson, David W.

Source: Chemistry - A European Journal; 12/15/2020, Vol. 26 Issue 70, p16818-16823, 6p

Subject Terms: ARYL bromides, AROMATIC amines, AMINATION, PROTEOLYSIS, UBIQUITIN ligases, UBIQUITINATION

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Expeditious Access to Functionalized Tricyclic Pyrrolo-Pyridones via Tandem or Sequential C–N/C–C Bond Formations.

Authors: Fillery, Shaun M., Gregson, Clare L., Guérot, Carine M.

Source: Organic Letters; Nov2019, Vol. 21 Issue 22, p9128-9132, 5p

Highly regioselective Buchwald–Hartwig amination at C-2 of 2,4-dichloropyridine enabling a novel approach to 2,4-bisanilinopyridine (BAPyd) libraries

Authors: Burton, Rebecca J., Crowther, Mandy L., Fazakerley, Neal J., Fillery, Shaun M., Hayter, Barry M., Kettle, Jason G., McMillan, Caroline A., Perkins, Paula, Robins, Peter, Smith, Peter M., Williams, Emma J., Wrigley, Gail L.

Source: In Tetrahedron Letters 11 December 2013 54(50):6900-6904

Sulfonyl-morpholino-pyrimidines: SAR and development of a novel class of selective mTOR kinase inhibitor

Authors: Finlay, M. Raymond V., Buttar, David, Critchlow, Susan E., Dishington, Allan P., Fillery, Shaun M., Fisher, Eric, Glossop, Steve C., Graham, Mark A., Johnson, Trevor, Lamont, Gillian M., Mutton, Simon, Perkins, Paula, Pike, Kurt G., Slater., Anthony M.

Source: In Bioorganic & Medicinal Chemistry Letters 15 June 2012 22(12):4163-4168

Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3,3-diphenylpropyl)-piperidinyl amides and ureas

Authors: Burrows, Jeremy N., Cumming, John G. ^*, Fillery, Shaun M., Hamlin, Gordon A., Hudson, Julian A., Jackson, Ruth J., McLaughlin, Sharon, Shaw, John S.

Source: In Bioorganic & Medicinal Chemistry Letters 2005 15(1):25-28

Facile synthesis of 3-alkoxyindoles via rhodium(II)-catalysed diazoindole O–H insertion reactions

Authors: Kettle, Jason G ^*, Faull, Alan W, Fillery, Shaun M, Flynn, Anthony P, Hoyle, Marcus A, Hudson, Julian A

Source: In Tetrahedron Letters 2000 41(35):6905-6907

Amination of Ethers Using Chloramine-T Hydrate and a Copper(I) Catalyst.

Authors: Albone, David P., Challenger, Stephen, Derrick, Andrew M., Fillery, Shaun M., Irwin, Jacob L., Parsons, Christopher M., Takada, Hiroya, Taylor, Paul C., Wilson, D. James.

Source: ChemInform; May2005, Vol. 36 Issue 20, pno-no, 1p

ChemInform Abstract: Facile Synthesis of 3-Alkoxyindoles via Rhodium(II)-Catalyzed Diazoindole O-H Insertion Reactions.

Authors: Kettle, Jason G., Faull, Alan W., Fillery, Shaun M., Flynn, Anthony P., Hoyle, Marcus A., Hudson, Julian A.

Source: ChemInform; Dec2000, Vol. 31 Issue 50, pno-no, 1p