High-throughput single-cell screening of viable hybridomas and patient-derived antibody-secreting cells using punchable microwells

Authors: Kaat Rubben, Ann-Sophie Vander Plaetsen, Ruben Almey, Olivier Tytgat, Koen Deserranno, Jamie Debaere, Delphine Diana Acar, Philip Meuleman, Dieter Deforce, Filip Van Nieuwerburgh

Source: Artificial Cells, Nanomedicine, and Biotechnology, Vol 52, Iss 1, Pp 426-436 (2024)

Subject Terms: Single-cell, high-throughput, antibody, hybridomas, antibody-secreting cells (ASCs), single-cell nested RT-PCR, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2169-1401; https://doaj.org/toc/2169-141X

Access URL: https://doaj.org/article/9885c7a30830402da954ea0931b49fc5

Extracellular vesicles from chronic lymphocytic leukemia cells promote leukemia aggressiveness by inducing the differentiation of monocytes into nurse‐like cells via an RNA‐dependent mechanism

Authors: Nathan Dubois, David Van Morckhoven, Laurentijn Tilleman, Filip Van Nieuwerburgh, Dominique Bron, Laurence Lagneaux, Basile Stamatopoulos

Source: HemaSphere, Vol 9, Iss 1, Pp n/a-n/a (2025)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/6669e67165374febae9a579fcd077482

Exploring seasonal dynamics of sea spray aerosol bioactivity: Insights into molecular effects on human bronchial epithelial cells

Authors: Zixia Liu, Emmanuel Van Acker, Maarten De Rijcke, Filip Van Nieuwerburgh, Colin Janssen, Jana Asselman

Source: Environment International, Vol 195, Iss , Pp 109255- (2025)

Subject Terms: sea spray aerosol (SSA), Bronchial epithelial cells, RNA sequencing, Biogenics hypothesis, mTOR pathway, Seasonal variation, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0160412025000066; https://doaj.org/toc/0160-4120

Access URL: https://doaj.org/article/b1d28474e0704cb09c0404841c1fd9d0

From follicle to blastocyst: microRNA-34c from follicular fluid-derived extracellular vesicles modulates blastocyst quality

Authors: Camilla Benedetti, Krishna Chaitanya Pavani, Yannick Gansemans, Nima Azari-Dolatabad, Osvaldo Bogado Pascottini, Luc Peelman, Rani Six, Yuan Fan, Xuefeng Guan, Koen Deserranno, Andrea Fernández-Montoro, Joachim Hamacher, Filip Van Nieuwerburgh, Trudee Fair, An Hendrix, Katrien Smits, Ann Van Soom

Source: Journal of Animal Science and Biotechnology, Vol 15, Iss 1, Pp 1-17 (2024)

Subject Terms: Developmental competence, Extracellular vesicles, Maturation, MicroRNA, miR-34c, Oocyte, Animal culture, SF1-1100, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://doaj.org/toc/2049-1891

Access URL: https://doaj.org/article/d8788538c45e4634a8aed19b6cd6ec72

Impact of nutrient excess on physiology and metabolism of Sulfolobus acidocaldarius

Authors: Viktor Laurin Sedlmayr, Diana Széliová, Veerke De Kock, Yannick Gansemans, Filip Van Nieuwerburgh, Eveline Peeters, Julian Quehenberger, Jürgen Zanghellini, Oliver Spadiut

Source: Frontiers in Microbiology, Vol 15 (2024)

Subject Terms: Sulfolobus acidocaldarius, chemostat cultivation, overflow metabolism, carbon overfeeding, fatty acid metabolism, transcriptomic analysis, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2024.1475385/full; https://doaj.org/toc/1664-302X

Access URL: https://doaj.org/article/8bfd793e02df4276bf25be5773f88434

A proteogenomic atlas of the human neural retina

Authors: Tabea V. Riepe, Merel Stemerdink, Renee Salz, Alfredo Dueñas Rey, Suzanne E. de Bruijn, Erica Boonen, Tomasz Z. Tomkiewicz, Michael Kwint, Jolein Gloerich, Hans J. C. T. Wessels, Emma Delanote, Elfride De Baere, Filip van Nieuwerburgh, Sarah De Keulenaer, Barbara Ferrari, Stefano Ferrari, Frauke Coppieters, Frans P. M. Cremers, Erwin van Wyk, Susanne Roosing, Erik de Vrieze, Peter A. C. ‘t Hoen

Source: Frontiers in Genetics, Vol 15 (2024)

Subject Terms: neural retina, isoform, alternative splicing, multi-omics, long-read sequencing, proteogenomics, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2024.1451024/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/597f13c9088a47f6afda9d373f062809

Genome-wide methylome stability and parental effects in the worldwide distributed Lombardy poplar

Authors: An Vanden Broeck, Tim Meese, Pieter Verschelde, Karen Cox, Berthold Heinze, Dieter Deforce, Ellen De Meester, Filip Van Nieuwerburgh

Source: BMC Biology, Vol 22, Iss 1, Pp 1-17 (2024)

Subject Terms: Black poplar, Bud phenology, DNA methylation, Epigenetics, Transgenerational plasticity, Populus nigra, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7007

Access URL: https://doaj.org/article/9203930b2d8a4294b5d1cff1620c39e3

Myeloid A20 is critical for alternative macrophage polarization and type-2 immune-mediated helminth resistance

Authors: Ioanna Petta, Marie Thorp, Maarten Ciers, Gillian Blancke, Louis Boon, Tim Meese, Filip Van Nieuwerburgh, Andy Wullaert, Richard Grencis, Dirk Elewaut, Geert van Loo, Lars Vereecke

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: immunity to parasites, helminth infection, innate immunity, adaptive immunity, type-2 response, macrophage polarization, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1373745/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/4430a9dec9a04b37b1e9e9b55eb09f9c

Proteomics data in vitiligo: a scoping review

Authors: Danique Berrevoet, Filip Van Nieuwerburgh, Dieter Deforce, Reinhart Speeckaert

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: proteomics, vitiligo, proteins, biomarkers, disease activity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1387011/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3248ad2235e1424c99f7769a976b862b

HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells

Authors: Tamara De Vos, Nicole Oatman, Lena Boehme, Tom Putteman, Imke Velghe, Yana Van Droogenbroeck, Stijn De Munter, Michaela Cesnekova, Filip Van Nieuwerburgh, Bart Vandekerckhove, Jan Philippe, Tom Taghon

Source: Haematologica, Vol 999, Iss 1 (2024)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11534; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/2ba793734fde41f4aa47b970e723784c

Average Nucleotide Identity and Digital DNA-DNA Hybridization Analysis Following PromethION Nanopore-Based Whole Genome Sequencing Allows for Accurate Prokaryotic Typing

Authors: Nick Versmessen, Marieke Mispelaere, Marjolein Vandekerckhove, Cedric Hermans, Jerina Boelens, Katleen Vranckx, Filip Van Nieuwerburgh, Mario Vaneechoutte, Paco Hulpiau, Piet Cools

Source: Diagnostics, Vol 14, Iss 16, p 1800 (2024)

Subject Terms: Escherichia coli, whole genome sequencing, multi-locus sequence typing, antibiotic resistance, species delineation, average nucleotide identity, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/14/16/1800; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/73acf6921a3b400fb8de34ac3161dc25

Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T‐cell lymphoblastic leukemia

Authors: André Almeida, Sara T'Sas, Luca Pagliaro, Igor Fijalkowski, Wouter Sleeckx, Hannah Van Steenberge, Raffaella Zamponi, Béatrice Lintermans, Wouter Van Loocke, Bruno Palhais, Alexandra Reekmans, Valentina Bardelli, Lisa Demoen, Lindy Reunes, Dieter Deforce, Filip Van Nieuwerburgh, Alex Kentsis, Panagiotis Ntziachristos, Nadine Van Roy, Barbara De Moerloose, Cristina Mecucci, Roberta La Starza, Giovanni Roti, Steven Goossens, Pieter Van Vlierberghe, Tim Pieters

Source: HemaSphere, Vol 8, Iss 3, Pp n/a-n/a (2024)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2572-9241

Access URL: https://doaj.org/article/08e4e181348c41af8c6b27ded628bcc2

Baselining physiological parameters in three muscles across three equine breeds. What can we learn from the horse?

Authors: Carmen Vidal Moreno de Vega, Constance de Meeûs d’Argenteuil, Berit Boshuizen, Lorie De Mare, Yannick Gansemans, Filip Van Nieuwerburgh, Dieter Deforce, Klara Goethals, Ward De Spiegelaere, Luc Leybaert, Elisabeth-Lidwien J.M.M. Verdegaal, Cathérine Delesalle

Source: Frontiers in Physiology, Vol 15 (2024)

Subject Terms: locomotor muscle, posture muscle, Warmblood horse, Friesian horse, Standardbred horse, baseline metabolism, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2024.1291151/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/b1d3a9f44acb41f7a4b3891e9972eb0f

Systematic comparison of experimental and human obstructive cholestasis reveals conservation of canonical pathway activation and biomarkers relevant for cholestatic liver disease

Authors: Eva Gijbels, Kevin De Muynck, Bart Vanderborght, Tim Meese, Filip Van Nieuwerburgh, Aude Vanlander, Frederik Berrevoet, Bart Hendrikx, Anne Hoorens, Hans Van Vlierberghe, Mathieu Vinken, Lindsey Devisscher

Source: Genes and Diseases, Vol 10, Iss 1, Pp 18-21 (2023)

Subject Terms: Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S235230422200040X; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/94beb4e0e3ca4367a404beb8dad94cd1

Targeted haplotyping in pharmacogenomics using Oxford Nanopore Technologies’ adaptive sampling

Authors: Koen Deserranno, Laurentijn Tilleman, Kaat Rubben, Dieter Deforce, Filip Van Nieuwerburgh

Source: Frontiers in Pharmacology, Vol 14 (2023)

Subject Terms: pharmacogenomics, oxford nanopore technologies sequencing, targeted sequencing, haplotyping, star-allele calling, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1286764/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/89ae39290b184bf9822d1b00b268edbc

Transcriptional and translational dynamics underlying heat shock response in the thermophilic crenarchaeon Sulfolobus acidocaldarius

Authors: Rani Baes, Felix Grünberger, Sébastien Pyr dit Ruys, Mohea Couturier, Sarah De Keulenaer, Sonja Skevin, Filip Van Nieuwerburgh, Didier Vertommen, Dina Grohmann, Sébastien Ferreira-Cerca, Eveline Peeters

Source: mBio, Vol 14, Iss 5 (2023)

Subject Terms: archaea, Sulfolobus, heat shock, integrated omics, gene regulation, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/3ce8b86181b3464b9989459b164879e3

Haplotyping pharmacogenes using TLA combined with Illumina or Nanopore sequencing

Authors: Laurentijn Tilleman, Kaat Rubben, Wim Van Criekinge, Dieter Deforce, Filip Van Nieuwerburgh

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/8dac01e2cff74827bcd4cde1082786a7

Guar gum as galactomannan source induces dysbiosis and reduces performance in broiler chickens and dietary β-mannanase restores the gut homeostasis

Authors: Marielen de Souza, Venessa Eeckhaut, Evy Goossens, Richard Ducatelle, Filip Van Nieuwerburgh, Karl Poulsen, Ana Angelita Sampaio Baptista, Ana Paula Frederico Rodrigues Loureiro Bracarense, Filip Van Immerseel

Source: Poultry Science, Vol 102, Iss 8, Pp 102810- (2023)

Subject Terms: beta-mannanase, guar gum, microbiota, mannan, gut health, Animal culture, SF1-1100

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0032579123003292; https://doaj.org/toc/0032-5791

Access URL: https://doaj.org/article/e9650b4eaa51408fb6662a9ce31db013

Dynamics of training and acute exercise-induced shifts in muscular glucose transporter (GLUT) 4, 8, and 12 expression in locomotion versus posture muscles in healthy horses

Authors: Carmen Vidal Moreno de Vega, Diete Lemmens, Constance de Meeûs d’Argenteuil, Berit Boshuizen, Lorie de Maré, Luc Leybaert, Klara Goethals, Jean Eduardo de Oliveira, Guilherme Hosotani, Dieter Deforce, Filip Van Nieuwerburgh, Lindsey Devisscher, Cathérine Delesalle

Source: Frontiers in Physiology, Vol 14 (2023)

Subject Terms: equine, exercise, training, metabolism, glucose, glycogen, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2023.1256217/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/a289334503f24e15bab43f018a7df3b8

Comparative transcriptomics of porcine liver-resident CD8αdim, liver CD8αhigh and circulating blood CD8αhigh NK cells reveals an intermediate phenotype of liver CD8αhigh NK cells

Authors: Leen Hermans, Sofie Denaeghel, Robert J. J. Jansens, Steffi De Pelsmaeker, Filip Van Nieuwerburgh, Dieter Deforce, Everardo Hegewisch-Solloa, Emily M. Mace, Eric Cox, Bert Devriendt, Herman W. Favoreel

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: liver-resident, NK cells, transcriptome, pig, plasticity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1219078/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/249d3b1fcb854cf5aeb496ceddaf121e