Association of Variants in IL-1RN (rs2234663) and IL-1β (rs1143627, rs16944) and Interleukin-1β Levels with Colorectal Cancer: Experimental Study and In Silico Analysis.

Authors: Gallegos-Arreola, Martha Patricia, Garibaldi-Ríos, Asbiel Felipe, Gutiérrez-Hurtado, Itzae Adonaí, Zúñiga-González, Guillermo Moisés, Figuera, Luis E., Gómez-Meda, Belinda Claudia, Puebla-Pérez, Ana María, García-Ortiz, José Elías, Delgado-Saucedo, Jorge I., Castro-García, Paola Beatriz, Rentería-Ramírez, María de Jesús, Torres-Mendoza, Blanca Miriam

Source: Genes; Dec2024, Vol. 15 Issue 12, p1528, 17p

Subject Terms: REGULATOR genes, GENETIC regulation, GENETIC polymorphisms, TOBACCO use, INFLAMMATION

Molecular Perspectives on Prostate Cancer: The Role of microRNAs in Androgen Receptor Regulation.

Authors: Garibaldi-Ríos, Asbiel Felipe, Rivera-Cameras, Alicia, Figuera, Luis E., Zúñiga-González, Guillermo Moisés, Gómez-Meda, Belinda Claudia, García-Ortíz, José Elías, Gallegos-Arreola, Martha Patricia

Source: Receptors; Dec2024, Vol. 3 Issue 4, p494-512, 19p

Subject Terms: ANDROGEN receptors, GENETIC regulation, PROSTATE cancer, MICRORNA, CANCER patients

Association Between the rs13306703 and rs8192288 Variants of the SOD3 Gene and Breast Cancer and an In Silico Analysis of the Variants' Impact.

Authors: Gallegos-Arreola, Martha Patricia, Garibaldi-Ríos, Asbiel Felipe, Magaña-Torres, María Teresa, Figuera, Luis E., Gómez-Meda, Belinda Claudia, Zúñiga-González, Guillermo Moisés, Puebla-Pérez, Ana María, Carrillo-Dávila, Irving Alejandro, Rosales-Reynoso, Mónica Alejandra, Dávalos-Rodríguez, Ingrid Patricia, Delgado-Saucedo, Jorge I., López-Monroy, Marco Uriel

Source: Diseases; Nov2024, Vol. 12 Issue 11, p276, 17p

Subject Terms: BRCA genes, GENETICS of breast cancer, GENETIC variation, ESTROGEN receptors, CANCER invasiveness, BREAST

Perceptions of Knowledge, Disease Impact and Predictive Genetic Testing in Family Members at Risk to Develop Early-Onset Alzheimer's Disease (EOAD) and Their Levels of Suicidal Ideation: A Mixed Study.

Authors: Reyes-Domínguez, Yesica Arlae¹ (AUTHOR) yesica.reyes2393@alumnos.udg.mx, Figuera, Luis E.^2,3 (AUTHOR) luis.figuera@academicos.udg.mx, Brambila-Tapia, Aniel Jessica Leticia⁴ (AUTHOR) aniel.brambila@academicos.udg.mx

Source: Brain Sciences (2076-3425). Mar2023, Vol. 13 Issue 3, p501. 10p.

Subject Terms: *ALZHEIMER'S disease, *SUICIDAL ideation, *GENETIC testing, *PREDICTIVE tests, *FAMILY counseling

Geographic Terms: JALISCO (Mexico), MEXICO

Autosomal dominant early onset Alzheimer's disease in the Mexican state of Jalisco: High frequency of the mutation PSEN1 c.1292C>A and phenotypic profile of patients

Authors: Dumois‐Petersen, Sofia, Gallegos‐Arreola, Martha P., Magaña‐Torres, María T., Perea‐Díaz, Francisco J., Ringman, John M., Figuera, Luis E.

Source: American journal of medical genetics.Part C.Seminars in medical genetics. 184(4):1023-1029

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112202317.0x000001&indx=1&recIds=ETOCvdc_100112202317.0x000001

Generalized hypertrichosis syndromes in Mexico

Authors: Aguayo‐Orozco, Thania Alejandra, Ríos‐González, Blanca Estela, Castro‐Martínez, Anna Gabriela, Ruiz‐Ramírez, Andrea Virginia, Figuera, Luis E.

Source: American journal of medical genetics.Part C.Seminars in medical genetics. 184(4):1014-1022

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112202315.0x000001&indx=1&recIds=ETOCvdc_100112202315.0x000001

The effect of years of schooling and age on CERAD‐MX performance in Mexican preclinical carriers of the APPV717I mutation: Randomized data simulation.

Authors: Zuno‐Reyes, Angélica, Pérez‐Rubio, Karina, Flores‐González, Martín Alonso, Torres, Ricardo Jauregui, Dumois‐Petersen, Sofía, Figuera, Luis E., Ringman, John M., Matute, Esmeralda

Source: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring; Jul2024, Vol. 16 Issue 3, p1-10, 10p

Subject Terms: ALZHEIMER'S disease, PRAXIS (Process), AGE factors in disease, CONSORTIA, STATISTICAL power analysis

In Silico Identification of Dysregulated miRNAs Targeting KRAS Gene in Pancreatic Cancer.

Authors: Garibaldi-Ríos, Asbiel Felipe, Figuera, Luis E., Zúñiga-González, Guillermo Moisés, Gómez-Meda, Belinda Claudia, García-Verdín, Patricia Montserrat, Carrillo-Dávila, Irving Alejandro, Gutiérrez-Hurtado, Itzae Adonai, Torres-Mendoza, Blanca Miriam, Gallegos-Arreola, Martha Patricia

Source: Diseases; Jul2024, Vol. 12 Issue 7, p152, 16p

Subject Terms: GENETIC regulation, GENE expression, RAS oncogenes, CANCER genes, PANCREATIC cancer

Early- and Late-Onset Alzheimer's Disease: Two Sides of the Same Coin?

Authors: Valdez-Gaxiola, César A., Rosales-Leycegui, Frida, Gaxiola-Rubio, Abigail, Moreno-Ortiz, José Miguel, Figuera, Luis E.

Source: Diseases; Jun2024, Vol. 12 Issue 6, p110, 29p

Subject Terms: ALZHEIMER'S disease, DISEASE progression, CRYPTOCURRENCIES

Association of the rs1966265 and rs351855 FGFR4 Variants with Colorectal Cancer in a Mexican Population and Their Analysis In Silico.

Authors: Carrillo-Dávila, Irving Alejandro, Garibaldi-Ríos, Asbiel Felipe, Figuera, Luis E., Gómez-Meda, Belinda Claudia, Zúñiga-González, Guillermo M., Puebla-Pérez, Ana María, García-Verdín, Patricia Montserrat, Castro-García, Paola Beatriz, Gutiérrez-Hurtado, Itzae Adonai, Torres-Mendoza, Blanca Miriam, Gallegos-Arreola, Martha Patricia

Source: Biomedicines; Mar2024, Vol. 12 Issue 3, p602, 16p

Subject Terms: MEXICANS, COLORECTAL cancer, RECTAL cancer, BLOOD testing, HAPLOTYPES, CANCER patients

Two familial intrachromosomal insertions with maternal dup(6)(p22.3p25.3) or dup(2)(q24.2q32.1) in recombinant offspring

Authors: Domínguez, María G., Rivera, Horacio, Aguilar-Lemarroy, Adriana, Jave-Suarez, Luis F., Ramírez-Velazco, Azubel, González-Ramos, Isaura A., Barros-Núñez, Patricio, Partida-Pérez, Miriam, Gutiérrez-Amavizca, Bianca E., Brambila-Tapia, Aniel JL., Figuera, Luis E.

Source: Clinical dysmorphology. 26(4):209-216

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100048591153.0x000001&indx=1&recIds=ETOCvdc_100048591153.0x000001

Potential Modifying Effect of the APOEε4 Allele on Age of Onset and Clinical Manifestations in Patients with Early-Onset Alzheimer's Disease with and without a Pathogenic Variant in PSEN1 in a Sample of the Mexican Population.

Authors: Valdez-Gaxiola, César A., Maciel-Cruz, Eric Jonathan, Hernández-Peña, Rubiceli, Dumois-Petersen, Sofía, Rosales-Leycegui, Frida, Gallegos-Arreola, Martha Patricia, Moreno-Ortiz, José Miguel, Figuera, Luis E.

Source: International Journal of Molecular Sciences; Nov2023, Vol. 24 Issue 21, p15687, 10p

Subject Terms: ALZHEIMER'S patients, AGE of onset, MEXICANS, SYMPTOMS, ALZHEIMER'S disease

Therapeutic goals in the treatment of Fabry disease

Authors: Mehta, Atul ^*, West, Michael L., Pintos-Morell, Guillem, Reisin, Ricardo, Nicholls, Kathy, Figuera, Luis E., Parini, Rossella, Carvalho, Luiz R., Kampmann, Christoph, Pastores, Gregory M., Lidove, Olivier

Source: In Genetics in Medicine November 2010 12(11):713-720

Effects of enzyme replacement therapy in Fabry disease—A comprehensive review of the medical literature

Authors: Lidove, Olivier ^*, West, Michael L., Pintos-Morell, Guillem, Reisin, Ricardo, Nicholls, Kathy, Figuera, Luis E., Parini, Rossella, Carvalho, Luiz R., Kampmann, Christoph, Pastores, Gregory M., Mehta, Atul

Source: In Genetics in Medicine November 2010 12(11):668-679

X-Linked Congenital Hypertrichosis Syndrome Is Associated with Interchromosomal Insertions Mediated by a Human-Specific Palindrome near SOX3

Authors: Zhu, Hongwen, Shang, Dandan, Sun, Miao, Choi, Sunju, Liu, Qing, Hao, Jiajie, Figuera, Luis E., Zhang, Feng, Choy, Kwong Wai, Ao, Yang, Liu, Yang, Zhang, Xiao-Lin, Yue, Fengzhen, Wang, Ming-Rong, Jin, Li, Patel, Pragna I., Jing, Tao, Zhang, Xue

Source: American journal of human genetics. 88(6):819-826

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100065935529.0x000001&indx=1&recIds=ETOCvdc_100065935529.0x000001

Prediction of Regulatory SNPs in Putative Minor Genes of the Neuro-Cardiovascular Variant in Fabry Reveals Insights into Autophagy/Apoptosis and Fibrosis.

Authors: Ruiz Ramírez, Andrea Virginia, Prado Montes de Oca, Ernesto, Figuera, Luis E

Source: Biology (2079-7737); Sep2022, Vol. 11 Issue 9, p1287-1287, 13p

Subject Terms: GENETIC variation, T helper cells, SINGLE nucleotide polymorphisms, B cells, ANGIOKERATOMA corporis diffusum, TRANSFORMING growth factors-beta, HEART cells

Clinical and molecular features of 66 patients with musculocontractural Ehlers−Danlos syndrome caused by pathogenic variants in CHST14 (mcEDS-CHST14).

Authors: Minatogawa, Mari, Ai Unzaki, Hiroko Morisaki, Syx, Delfien, Tohru Sonoda, Janecke, Andreas R., Slavotinek, Anne, Voermans, Nicol C., Lacassie, Yves, Mendoza-Londono, Roberto, Wierenga, Klaas J., Jayakar, Parul, Gahl, William A., Tifft, Cynthia J., Figuera, Luis E., Hilhorst-Hofstee, Yvonne, Maugeri, Alessandra, Ken Ishikawa, Tomoko Kobayashi, Yoko Aoki

Source: Journal of Medical Genetics; Sep2022, Vol. 59 Issue 9, p865-877, 13p

ESR2 gene variants (rs1256049, rs4986938, and rs1256030) and their association with breast cancer risk.

Authors: Patricia Gallegos-Arreola, Martha, Zúñiga-González, Guillermo M., Figuera, Luis E., Puebla-Pérez, Ana María, Márquez-Rosales, María Guadalupe, Claudia Gómez-Meda, Belinda, Alejandra Rosales-Reynoso, Mónica

Source: PeerJ; May2022, p1-17, 17p

Subject Terms: GENETIC variation, DISEASE risk factors, BREAST cancer, LYMPHATIC metastasis, MEXICANS

Pure partial trisomy 6p due to a familial insertion (16;6)(p12;p21.2p23)

Authors: Domínguez, María G., Wong-Ley, Luis E., Rivera, Horacio ^*, Vásquez, Ana I., Ramos, Alma L., Sánchez-Urbina, Rocío, Morales, J.A., Figuera, Luis E.

Source: In Annales de genetique 2003 46(1):45-48

Clinical and molecular features of 66 patients with musculocontractural Ehlers−Danlos syndrome caused by pathogenic variants in CHST14(mcEDS-CHST14)

Authors: Minatogawa, Mari, Unzaki, Ai, Morisaki, Hiroko, Syx, Delfien, Sonoda, Tohru, Janecke, Andreas R, Slavotinek, Anne, Voermans, Nicol C, Lacassie, Yves, Mendoza-Londono, Roberto, Wierenga, Klaas J, Jayakar, Parul, Gahl, William A, Tifft, Cynthia J, Figuera, Luis E, Hilhorst-Hofstee, Yvonne, Maugeri, Alessandra, Ishikawa, Ken, Kobayashi, Tomoko, Aoki, Yoko, Ohura, Toshihiro, Kawame, Hiroshi, Kono, Michihiro, Mochida, Kosuke, Tokorodani, Chiho, Kikkawa, Kiyoshi, Morisaki, Takayuki, Kobayashi, Tetsuyuki, Nakane, Takaya, Kubo, Akiharu, Ranells, Judith D, Migita, Ohsuke, Sobey, Glenda, Kaur, Anupriya, Ishikawa, Masumi, Yamaguchi, Tomomi, Matsumoto, Naomichi, Malfait, Fransiska, Miyake, Noriko, Kosho, Tomoki

Source: Journal of Medical Genetics (JMG); 2022, Vol. 59 Issue: 9 p865-877, 13p