Violacein switches off low molecular weight tyrosine phosphatase and rewires mitochondria in colorectal cancer cells

Authors: Faria, Alessandra V.S., Fonseca, Emanuella M.B., Fernandes-Oliveira, Patrícia de S., de Lima, Tanes I., Clerici, Stefano P., Justo, Giselle Z., Silveira, Leonardo R., Durán, Nelson, Ferreira-Halder, Carmen V.

Source: In Bioorganic Chemistry October 2022 127

Violacein negatively modulates the colorectal cancer survival and epithelial–mesenchymal transition

Authors: Souza Oliveira, Patricia F., Faria, Alessandra V. S., Clerici, Stefano P., Akagi, Erica M., Carvalho, Hernandes F., Justo, Giselle Z., Durán, Nelson, Ferreira‐Halder, Carmen V.

Source: Journal of cellular biochemistry. 123(7):1247-1258

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156087059.0x000001&indx=1&recIds=ETOCvdc_100156087059.0x000001

Platelet-dependent signaling and Low Molecular Weight Protein Tyrosine Phosphatase expression promote aggressive phenotypic changes in gastrointestinal cancer cells

Authors: Faria, Alessandra V.S., Yu, Bingting, Mommersteeg, Michiel, de Souza-Oliveira, Patrícia F., Andrade, Sheila S., Spaander, Manon C.W., de Maat, Moniek P.M., Peppelenbosch, Maikel P., Ferreira-Halder, Carmen V., Fuhler, Gwenny M.

Source: In BBA - Molecular Basis of Disease 1 January 2022 1868(1)

The role of phospho-tyrosine signaling in platelet biology and hemostasis

Authors: Faria, Alessandra V.S., Andrade, Sheila S., Peppelenbosch, Maikel P., Ferreira-Halder, Carmen V., Fuhler, Gwenny M.

Source: In BBA - Molecular Cell Research March 2021 1868(3)

Platelets in aging and cancer—'double-edged sword'

Authors: Faria, Alessandra V. S., Andrade, Sheila S., Peppelenbosch, Maikel P., Ferreira-Halder, Carmen V., Fuhler, Gwenny M.

Source: Cancer and metastasis reviews. 39(4):1205-1221

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187143644.0x000001&indx=1&recIds=ETOCvdc_100187143644.0x000001

LMWPTP modulates the antioxidant response and autophagy process in human chronic myeloid leukemia cells

Authors: Faria, Alessandra V. S., Clerici, Stefano P., de Souza Oliveira, Patricia F., Queiroz, Karla C. S., Peppelenbosch, Maikel P., Ferreira-Halder, Carmen V.

Source: MOLECULAR AND CELLULAR BIOCHEMISTRY. 466(1-2):83-89

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164080227.0x000001&indx=1&recIds=ETOCvdc_100164080227.0x000001

Crystal structures of the apo form and a complex of human LMW-PTP with a phosphonic acid provide new evidence of a secondary site potentially related to the anchorage of natural substrates

Authors: Fonseca, Emanuella M.B., Trivella, Daniela B.B., Scorsato, Valéria, Dias, Mariana P., Bazzo, Natália L., Mandapati, Kishore R., de Oliveira, Fábio L., Ferreira-Halder, Carmen V., Pilli, Ronaldo A., Miranda, Paulo C.M.L., Aparicio, Ricardo

Source: In Bioorganic & Medicinal Chemistry 1 August 2015 23(15):4462-4471

Oncophosphosignaling Favors a Glycolytic Phenotype in Human Drug Resistant Leukemia

Authors: Faria, Alessandra V.S., Tornatore, Thaís F., Milani, Renato, Queiroz, Karla C.S., Sampaio, Igor H., Fonseca, Emanuella M.B., Rocha‐Brito, Karin J.P., Santos, Tamira O., Silveira, Leonardo R., Peppelenbosch, Maikel P., Ferreira‐Halder, Carmen V.

Source: Journal of cellular biochemistry. 118(11):3846-3854

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116950287.0x000001&indx=1&recIds=ETOCvdc_100116950287.0x000001

Crosstalk between kinases, phosphatases and miRNAs in cancer

Authors: Abrantes, Júlia L.F., Tornatore, Thaís F., Pelizzaro-Rocha, Karin J., de Jesus, Marcelo B., Cartaxo, Rodrigo T., Milani, Renato, Ferreira-Halder, Carmen V.

Source: In Biochimie December 2014 107 Part B:167-187

Violacein negatively modulates the colorectal cancer survival and epithelial–mesenchymal transition.

Authors: de Souza Oliveira, Patricia F., Faria, Alessandra V. S., Clerici, Stefano P., Akagi, Erica M., Carvalho, Hernandes F., Justo, Giselle Z., Durán, Nelson, Ferreira‐Halder, Carmen V.

Source: Journal of Cellular Biochemistry; Jul2022, Vol. 123 Issue 7, p1247-1258, 12p

Quercetin increases mitochondrial proteins (VDAC and SDH) and downmodulates AXL and PIM-1 tyrosine kinase receptors in NRAS melanoma cells.

Authors: Rocha-Brito, Karin J. P., Clerici, Stefano Piatto, Cordeiro, Helon Guimarães, Scotá Ferreira, Amanda Petrina, Barreto Fonseca, Emanuella Maria, Gonçalves, Paola R., Abrantes, Júlia Laura F., Milani, Renato, Massaro, Renato Ramos, Maria-Engler, Silvya Stuchi, Ferreira-Halder, Carmen V.

Source: Biological Chemistry; Feb2022, Vol. 403 Issue 3, p293-303, 11p

Subject Terms: MITOCHONDRIAL proteins, PROTEIN-tyrosine kinases, QUERCETIN, SUCCINATE dehydrogenase, MELANOMA, MICROPHTHALMIA-associated transcription factor, CHLORIDE channels

Multi-target drug with potential applications: violacein in the spotlight.

Authors: Durán, Nelson, Nakazato, Gerson, Durán, Marcela, Berti, Ignasio R., Castro, Guillermo R., Stanisic, Danijela, Brocchi, Marcelo, Fávaro, Wagner J., Ferreira-Halder, Carmen V., Justo, Giselle Z., Tasic, Ljubica

Source: World Journal of Microbiology & Biotechnology; Sep2021, Vol. 37 Issue 9, p1-20, 20p

Subject Terms: DRUG delivery systems, ANTINEOPLASTIC agents, CELL death, CHROMOBACTERIUM violaceum

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

Biotech-Educated Platelets: Beyond Tissue Regeneration 2.0.

Authors: Andrade, Sheila Siqueira, Faria, Alessandra Valéria de Sousa, Girão, Manoel João Batista C., Fuhler, Gwenny M., Peppelenbosch, Maikel P., Ferreira-Halder, Carmen V.

Source: International Journal of Molecular Sciences; Sep2020, Vol. 21 Issue 17, p6061-6061, 1p

Subject Terms: BIOMIMETIC materials, TISSUE engineering, TISSUES, BIOMATERIALS, BIOLOGY

Correction: Faria, A.V.S. et al., Targeting Tyrosine Phosphatases by 3-Bromopyruvate Overcomes Hyperactivation of Platelets from Gastrointestinal Cancer Patients. J. Clin. Med. 2019, 8, 936.

Authors: Faria, Alessandra V. S., Andrade, Sheila S., Reijm, Agnes N., Spaander, Manon C. W., de Maat, Moniek P. M., Peppelenbosch, Maikel P., Ferreira-Halder, Carmen V., Fuhler, Gwenny M.

Source: Journal of Clinical Medicine; Aug2020, Vol. 9 Issue 8, p2625, 1p

Subject Terms: GASTROINTESTINAL cancer, PHOSPHATASES, CANCER patients, TYROSINE, BLOOD platelets

This result is not displayed to guests.
Login for full access.

Targeting Tyrosine Phosphatases by 3-Bromopyruvate Overcomes Hyperactivation of Platelets from Gastrointestinal Cancer Patients.

Authors: Faria, Alessandra V. S., Andrade, Sheila S., Reijm, Agnes N., Spaander, Manon C. W., de Maat, Moniek P. M., Peppelenbosch, Maikel P., Ferreira-Halder, Carmen V., Fuhler, Gwenny M.

Source: Journal of Clinical Medicine; Oct2019, Vol. 8 Issue 10, p936, 1p

Subject Terms: GASTROINTESTINAL cancer, PHOSPHATASES, BLOOD platelets, BLOOD platelet disorders, BLOOD platelet aggregation, PHOSPHOPROTEIN phosphatases

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.