Enhanced Impedance Flow Cytometry via Acoustic-Driven Microparticle Focusing in Microchannels

Authors: Zhou, Peng, Xu, Yingming, Simon, Terrence, Fernandez-Zapico, Martin E., Ma, Wen Wee, Cui, Tianhong

Source: 2024 IEEE 37th International Conference on Micro Electro Mechanical Systems (MEMS) Micro Electro Mechanical Systems (MEMS), 2024 IEEE 37th International Conference on. :1130-1133 Jan, 2024

Relation: 2024 IEEE 37th International Conference on Micro Electro Mechanical Systems (MEMS)

The multi-faceted roles of cancer-associated fibroblasts in pancreatic cancer

Authors: Kwon, John Y., Vera, Renzo E., Fernandez-Zapico, Martin E. ^⁎

Source: In Cellular Signalling March 2025 127

Enhancing immune response and survival in hepatocellular carcinoma with novel oncolytic Jurona virus and immune checkpoint blockade

Authors: Tesfay, Mulu Z., Zhang, Yuguo, Ferdous, Khandoker U., Taylor, Mika A., Cios, Aleksandra, Shelton, Randal S., Simoes, Camila C., Watters, Chelsae R., Barro, Oumar, Elliott, Natalie M., Mustafa, Bahaa, Chamcheu, Jean Christopher, Graham, Alicia L., Washam, Charity L., Alkam, Duah, Gies, Allen, Byrum, Stephanie D., Giorgakis, Emmanouil, Post, Steven R., Kelly, Thomas, Ying, Jun, Moaven, Omeed, Chabu, Chiswili Y., Fernandez-Zapico, Martin E., Duda, Dan G., Roberts, Lewis R., Govindarajan, Rang, Borad, Mitesh J., Cannon, Martin J., Basnakian, Alexei G., Nagalo, Bolni M.

Source: In Molecular Therapy: Oncology 19 December 2024 32(4)

Epigenetic regulation of the tumor microenvironment: A leading force driving pancreatic cancer

Authors: Vera, Renzo, Lamberti, María Julia, Gonzalez, Alina L., Fernandez-Zapico, Martín E.

Source: In Pancreatology September 2024 24(6):878-886

Translational relevance of SOS1 targeting for KRAS‐mutant colorectal cancer

Authors: Alem, Diego, Yang, Xinrui, Beato, Francisca, Sarcar, Bhaswati, Tassielli, Alexandra F., Dai, Ruifan, Hogenson, Tara L., Park, Margaret A., Jiang, Kun, Cai, Jianfeng, Yuan, Yu, Fernandez‐Zapico, Martin E., Tan, Aik Choon, Fleming, Jason B., Xie, Hao

Source: Molecular carcinogenesis. 62(7):1025-1037

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185325294.0x000001&indx=1&recIds=ETOCvdc_100185325294.0x000001

GLI1, a novel target of the ER stress regulator p97/VCP, promotes ATF6f-mediated activation of XBP1

Authors: Almada, Luciana L., Barroso, Kim, Sen, Sandhya, Toruner, Murat, Sigafoos, Ashley N., Raja Arul, Glancis L., Pease, David R., Vera, Renzo E., Olson, Rachel L.O., Auner, Holger W., Pedeux, Rémy, Iovanna, Juan L., Chevet, Eric, Fernandez-Zapico, Martin E.

Source: In BBA - Gene Regulatory Mechanisms June 2023 1866(2)

MLL1 inhibition reduces IgM levels in Waldenström macroglobulinemia

Authors: Karbalivand, Mona, Almada, Luciana L., Ansell, Stephen M., Fernandez-Zapico, Martin E., Elsawa, Sherine F.

Source: In Leukemia Research May 2022 116

Cancer imaging and therapy utilizing a novel NIS-expressing adenovirus: The role of adenovirus death protein deletion

Authors: Robertson, Matthew Glen, Eidenschink, Benjamin Bruce, Iguchi, Eriko, Zakharkin, Stanislav O., LaRocca, Christopher J., Tolosa, Ezequiel J., Truty, Mark J., Jacobsen, Kari, Fernandez-Zapico, Martin E., Davydova, Julia

Source: In Molecular Therapy - Oncolytics 26 March 2021 20:659-668

A rare germline CDKN2A variant (47T>G; p16-L16R) predisposes carriers to pancreatic cancer by reducing cell cycle inhibition

Authors: Horn, Isaac P., Marks, David L., Koenig, Amanda N., Hogenson, Tara L., Almada, Luciana L., Goldstein, Lauren E., Romecin Duran, Paola A., Vera, Renzo, Vrabel, Anne M., Cui, Gaofeng, Rabe, Kari G., Bamlet, William R., Mer, Georges, Sicotte, Hugues, Zhang, Cheng, Li, Hu, Petersen, Gloria M., Fernandez-Zapico, Martin E.

Source: In Journal of Biological Chemistry January-June 2021 296

E3 ubiquitin ligase PARK2, an inhibitor of melanoma cell growth, is repressed by the oncogenic ERK1/2-ELK1 transcriptional axis

Authors: Montagnani, Valentina, Maresca, Luisa, Apollo, Alessandro, Pepe, Sara, Carr, Ryan M., Fernandez-Zapico, Martin E., Stecca, Barbara ^*

Source: In Journal of Biological Chemistry 20 November 2020 295(47):16058-16071

Targeting of the Hedgehog/GLI and mTOR pathways in advanced pancreatic cancer, a phase 1 trial of Vismodegib and Sirolimus combination

Authors: Carr, Ryan M., Duma, Narjust, McCleary-Wheeler, Angela L., Almada, Luciana L., Marks, David L., Graham, Rondell P., Smyrk, Thomas C., Lowe, Val, Borad, Mitesh J., Kim, George, Johnson, Geoffrey B., Allred, Jacob B., Yin, Jun, Lim, Vun-Sin, Bekaii-Saab, Tanios, Ma, Wen We, Erlichman, Charles, Adjei, Alex A., Fernandez-Zapico, Martin E.

Source: In Pancreatology September 2020 20(6):1115-1122

The transcription factor GLI1 cooperates with the chromatin remodeler SMARCA2 to regulate chromatin accessibility at distal DNA regulatory elements

Authors: Safgren, Stephanie L., Olson, Rachel L.O., Vrabel, Anne M., Almada, Luciana L., Marks, David L., Hernandez-Alvarado, Nelmary, Gaspar-Maia, Alexandre, Fernandez-Zapico, Martin E. ^*

Source: In Journal of Biological Chemistry 26 June 2020 295(26):8725-8735

Understanding Suboptimal Response to Immune Checkpoint Inhibitors

Authors: Zhu, Mojun, Zhang, Henan, Pedersen, Katrina S., Foster, Nathan R., Jaszewski, Brandy L., Liu, Xin, Hirdler, Jacob B., An, Zesheng, Bekaii‐Saab, Tanios S., Halfdanarson, Thorvardur R., Boland, Patrick M., Yan, Yiyi, Hubbard, Joleen H., Ma, Wen Wee, Yoon, Harry H., Revzin, Alexander, Fernandez‐Zapico, Martin E., Overman, Michael J., McWilliams, Robert R., Dong, Haidong

Source: Advanced biology. 7(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100181410950.0x000001&indx=1&recIds=ETOCvdc_100181410950.0x000001

The extracellular sulfatase SULF2 promotes liver tumorigenesis by stimulating assembly of a promoter-looping GLI1-STAT3 transcriptional complex

Authors: Carr, Ryan M., Romecin Duran, Paola A., Tolosa, Ezequiel J., Ma, Chenchao, Oseini, Abdul M., Moser, Catherine D., Banini, Bubu A., Huang, Jianbo, Asumda, Faizal, Dhanasekaran, Renumathy, Graham, Rondell P., Toruner, Merih D., Safgren, Stephanie L., Almada, Luciana L., Wang, Shaoqing, Patnaik, Mrinal M., Roberts, Lewis R., Fernandez-Zapico, Martin E.

Source: In Journal of Biological Chemistry 28 February 2020 295(9):2698-2712

ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells

Authors: Liu, Mingyang, Zhang, Yuqing, Yang, Jingxuan, Cui, Xiaobo, Zhou, Zhijun, Zhan, Hanxiang, Ding, Kai, Tian, Xiang, Yang, Zhibo, Fung, Kar-Ming A., Edil, Barish H., Postier, Russell G., Bronze, Michael S., Fernandez-Zapico, Martin E., Stemmler, Marc P., Brabletz, Thomas, Li, Yi-Ping, Houchen, Courtney W., Li, Min

Source: In Gastroenterology February 2020 158(3):679-692

Phase 1 trial of Vismodegib and Erlotinib combination in metastatic pancreatic cancer

Authors: McCleary-Wheeler, Angela L., Carr, Ryan M., Palmer, Shanique R., Smyrk, Thomas C., Allred, Jacob B., Almada, Luciana L., Tolosa, Ezequiel J., Lamberti, Maria J., Marks, David L., Borad, Mitesh J., Molina, Julian R., Qi, Yingwei, Lingle, Wilma L., Grothey, Axel, Pitot, Henry C., Jatoi, Aminah, Northfelt, Donald W., Bryce, Alan H., McWilliams, Robert R., Okuno, Scott H., Haluska, Paul, Kim, George P., Colon-Otero, Gerardo, Lowe, Val J., Callstrom, Matthew R., Ma, Wen We, Bekaii-Saab, Tanios, Hung, Mien-Chie, Erlichman, Charles, Fernandez-Zapico, Martin E.

Source: In Pancreatology January 2020 20(1):101-109

Response to erythropoiesis‐stimulating agents in patients with WHO‐defined myelodysplastic syndrome/myeloproliferative neoplasm with ring sideroblasts and thrombocytosis (MDS/MPN‐RS‐T)

Authors: Antelo, Guadalupe, Mangaonkar, Abhishek A., Coltro, Giacomo, Buradkar, Ajinkya, Lasho, Terra L., Finke, Christy, Carr, Ryan, Binder, Moritz, Gangat, Naseema, Al‐Kali, Aref, Elliott, Michelle A., King, Rebecca L., Howard, Matthew, Melody, Megan E., Hogan, William, Litzow, Mark R, Tefferi, Ayalew, Fernandez‐Zapico, Martin E., Komrokji, Rami, Patnaik, Mrinal M.

Source: British journal of haematology. 189(3):e104-e108

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Phenotypic correlates and prognostic outcomes of TET2 mutations in myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes: A comprehensive study of 504 adult patients

Authors: Coltro, Giacomo, Antelo, Guadalupe, Lasho, Terra L., Finke, Christy M., Pardanani, Animesh, Gangat, Naseema, Carr, Ryan M., Binder, Moritz, Mangaonkar, Abhishek A., Ketterling, Rhett, Fernandez‐Zapico, Martin E., Robertson, Keith D., Bosi, Alberto, Vannucchi, Alessandro M., Tefferi, Ayalew, Patnaik, Mrinal M.

Source: American journal of hematology. 95(4):E86-E89

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116428757.0x000001&indx=1&recIds=ETOCvdc_100116428757.0x000001

Impaired Hedgehog-Gli1 Pathway Activity Underlies the Vascular Phenotype of Polycystic Kidney Disease

Authors: Franchi, Federico, Peterson, Karen M., Quandt, Katherine, Domnick, David, Kline, Timothy L., Olthoff, Michaela, Parvizi, Mojtaba, Tolosa, Ezequiel J., Torres, Vicente E., Harris, Peter C., Fernandez-Zapico, Martin E., Rodriguez-Porcel, Martin G.

Source: Hypertension. 76(6):1889-1897

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176819405.0x000001&indx=1&recIds=ETOCvdc_100176819405.0x000001

Tumor-derived GLI1 promotes remodeling of the immune tumor microenvironment in melanoma.

Authors: Giammona, Alessandro, De Vellis, Chiara, Crivaro, Enrica, Maresca, Luisa, Amoriello, Roberta, Ricci, Federica, Anichini, Giulia, Pietrobono, Silvia, Pease, David R., Fernandez-Zapico, Martin E., Ballerini, Clara, Stecca, Barbara

Source: Journal of Experimental & Clinical Cancer Research (17569966); 8/2/2024, Vol. 43 Issue 1, p1-20, 20p