ASTCT Consensus Recommendations on Testing and Treatment of Patients with Donor-specific Anti-HLA Antibodies

Authors: Kongtim, Piyanuch, Vittayawacharin, Pongthep, Zou, Jun, Srour, Samer, Shaffer, Brian, Shapiro, Roman M., Varma, Ankur, McGuirk, Joseph, Dholaria, Bhagirathbhai R., McCurdy, Shannon R., DeZern, Amy E., Bejanyan, Nelli, Bashey, Asad, Furst, Sabine, Castagna, Luca, Mariotti, Jacopo, Ruggeri, Annalisa, Bailen, Rebeca, Teshima, Takanori, Xiao-Jun, Huang, Bonfim, Carmen, Aung, Fleur, Cao, Kai, Carpenter, Paul A., Hamadani, Mehdi, Askar, Medhat, Fernandez-Vina, Marcelo, Girnita, Alin, Ciurea, Stefan O.

Source: In Transplantation and Cellular Therapy December 2024 30(12):1139-1154

An archaic HLA class I receptor allele diversifies natural killer cell-driven immunity in First Nations peoples of Oceania

Authors: Loh, Liyen ^{1, 2, 20}, Saunders, Philippa M. ^{1, 20}, Faoro, Camilla ^{3, 20}, Font-Porterias, Neus ^{4, 20}, Nemat-Gorgani, Neda ⁵, Harrison, Genelle F. ⁴, Sadeeq, Suraju ⁴, Hensen, Luca ¹, Wong, Shu Cheng ¹, Widjaja, Jacqueline ¹, Clemens, E. Bridie ¹, Zhu, Shiying ³, Kichula, Katherine M. ⁴, Tao, Sudan ^{4, 6}, Zhu, Faming ⁶, Montero-Martin, Gonzalo ⁷, Fernandez-Vina, Marcelo ⁷, Guethlein, Lisbeth A. ⁵, Vivian, Julian P. ³, Davies, Jane ^{8, 9}, Mentzer, Alexander J. ^{10, 11}, Oppenheimer, Stephen J. ¹², Pomat, William ¹³, Ioannidis, Alexander G. ¹⁴, Barberena-Jonas, Carmina ¹⁵, Moreno-Estrada, Andrés ¹⁵, Miller, Adrian ¹⁶, Parham, Peter ⁵, Rossjohn, Jamie ^{3, 17, 21, ∗}, Tong, Steven Y.C. ^{18, 19, 21, ∗∗}, Kedzierska, Katherine ^{1, 21, ∗∗∗}, Brooks, Andrew G. ^{1, 21, ∗∗∗∗}, Norman, Paul J. ^{2, 4, 5, 21, 22, ∗∗∗∗∗}

Source: In Cell 27 November 2024 187(24):7008-7024

Interleukin (IL)-1/IL-6-Inhibitor–Associated Drug Reaction With Eosinophilia and Systemic Symptoms (DReSS) in Systemic Inflammatory Illnesses

Authors: Aamir, R., Abulaban, K., Adams, A., Lapsia, C. Aguiar, Akinsete, A., Akoghlanian, S., Al Manaa, M., AlBijadi, A., Allenspach, E., Almutairi, A., Alperin, R., Amarilyo, G., Ambler, W., Amoruso, M., Angeles-Han, S., Ardoin, S., Armendariz, S., Asfaw, L., Aviran Dagan, N., Bacha, C., Balboni, I., Balevic, S., Ballinger, S., Baluta, S., Barillas-Arias, L., Basiaga, M., Baszis, K., Baxter, S., Becker, M., Begezda, A., Behrens, E., Beil, E., Benseler, S., Bermudez-Santiago, L., Bernal, W., Bigley, T., Bingham, C., Binstadt, B., Black, C., Blackmon, B., Blakley, M., Bohnsack, J., Boneparth, A., Bradfield, H., Bridges, J., Brooks, E., Brothers, M., Brunner, H., Buckley, L., Buckley, M., Bukulmez, H., Bullock, D., Canna, S., Cannon, L., Canny, S., Cartwright, V., Cassidy, E., Castro, D., Chalom, E., Chang, J., Chang, M., Chang-Hoftman, A., Chen, A., Chiraseveenuprapund, P., Ciaglia, K., Co, D., Cohen, E., Collinge, J., Conlon, H., Connor, R., Cook, K., Cooper, A., Cooper, J., Corbin, K., Correll, C., Cron, R., Curry, M., Dalrymple, A., Datyner, E., Davis, T., De Ranieri, D., Dean, J., DeCoste, C., Dedeoglu, F., DeGuzman, M., Delnay, N., DeSantis, E., Devine, R., Dhalla, M., Dhanrajani, A., Dissanayake, D., Dizon, B., Drapeau, N., Drew, J., Driest, K., Du, Q., Duncan, E., Dunnock, K., Durkee, D., Dvergsten, J., Eberhard, A., Ede, K., Edelheit, B., Edens, C., El Tal, T., Elder, M., Elzaki, Y., Fadrhonc, S., Failing, C., Fair, D., Favier, L., Feldman, B., Fennell, J., Ferguson, P., Ferguson, I., Figueroa, C., Flanagan, E., Fogel, L., Fox, E., Fox, M., Franklin, L., Fuhlbrigge, R., Fuller, J., Furey, M., Futch-West, T., Gagne, S., Gennaro, V., Gerstbacher, D., Gilbert, M., Gironella, A., Glaser, D., Goh, I., Goldsmith, D., Gorry, S., Goswami, N., Gottlieb, B., Graham, T., Grevich, S., Griffin, T., Grim, A., Grom, A., Guevara, M., Hahn, T., Halyabar, O., Hamda Natur, M., Hammelev, E., Hammond, T., Harel, L., Harris, J., Harry, O., Hausmann, J., Hay, A., Hays, K., Hayward, K., Henderson, L., Henrickson, M., Hersh, A., Hickey, K., Hiraki, L., Hiskey, M., Hobday, P., Hoffart, C., Holland, M., Hollander, M., Hong, S., Horton, D., Horwitz, M., Hsu, J., Huber, A., Huberts, A., Huggins, J., Huie, L., Hui-Yuen, J., Ibarra, M., Imlay, A., Imundo, L., Inman, C., Jackson, A., James, K., Janow, G., Jared, S., Jiang, Y., Johnson, L., Johnson, N., Jones, J., Kafisheh, D., Kahn, P., Kaidar, K., Kasinathan, S., Kaur, R., Kessler, E., Kienzle, B., Kim, S., Kimura, Y., Kingsbury, D., Kitcharoensakkul, M., Klausmeier, T., Klein, K., Klein-Gitelman, M., Knight, A., Kovalick, L., Kramer, S., Kremer, C., Kudas, O., LaFlam, T., Lang, B., Lapidus, S., Lapin, B., Lasky, A., Lawler, C., Lawson, E., Laxer, R., Lee, P., Lee, T., Lee, A., Leisinger, E., Lentini, L., Lerman, M., Levinsky, Y., Levy, D., Li, S., Lieberman, S., Lim, L., Limenis, E., Lin, C., Ling, N., Lionetti, G., Livny, R., Lloyd, M., Lo, M., Long, A., Lopez-Peña, M., Lovell, D., Luca, N., Lvovich, S., Lytch, A., Ma, M., Machado, A., MacMahon, J., Madison, J., Mannion, M., Manos, C., Mansfield, L., Marston, B., Mason, T., Matchett, D., McAllister, L., McBrearty, K., McColl, J., McCurdy, D., McDaniels, K., McDonald, J., Meidan, E., Mellins, E., Mian, Z., Miettunen, P., Miller, M., Milojevic, D., Mitacek, R., Modica, R., Mohan, S., Moore, T., Moore, K., Moorthy, L., Moreno, J., Morgan, E., Moyer, A., Murante, B., Murphy, A., Muscal, E., Mwizerwa, O., Najafi, A., Nanda, K., Nasah, N., Nassi, L., Nativ, S., Natter, M., Nearanz, K., Neely, J., Newhall, L., Nguyen, A., Nigrovic, P., Nocton, J., Nolan, B., Nowicki, K., Oakes, R., Oberle, E., Ogbonnaya-Whittesley, S., Ogbu, E., Oliver, M., Olveda, R., Onel, K., Orandi, A., Padam, J., Paller, A., Pan, N., Pandya, J., Panupattanapong, S., Toledano, A. Pappo, Parsons, A., Patel, J., Patel, P., Patrick, A., Patrizi, S., Paul, S., Perfetto, J., Perron, M., Peskin, M., Ponder, L., Pooni, R., Prahalad, S., Puplava, B., Quinlan-Waters, M., Rabinovich, C., Rafko, J., Rahimi, H., Rampone, K., Ramsey, S., Randell, R., Ray, L., Reed, A., Reid, H., Reiff, D., Richins, S., Riebschleger, M., Rife, E., Riordan, M., Riskalla, M., Robinson, A., Robinson, L., Rodgers, L., Rodriquez, M., Rogers, D., Ronis, T., Rosado, A., Rosenkranz, M., Rosenwasser, N., Rothermel, H., Rothman, D., Rothschild, E., Roth-Wojcicki, E., Rouster-Stevens, K., Rubinstein, T., Rupp, J., Ruth, N., Sabbagh, S., Sadun, R., Santiago, L., Saper, V., Sarkissian, A., Scalzi, L., Schahn, J., Schikler, K., Schlefman, A., Schmeling, H., Schmitt, E., Schneider, R., Schulert, G., Schultz, K., Schutt, C., Seper, C., Sheets, R., Shehab, A., Shenoi, S., Sherman, M., Shirley, J., Shishov, M., Siegel, D., Singer, N., Sivaraman, V., Sloan, E., Smith, C., Smith, J., Smitherman, E., Soep, J., Son, Mary B., Sosna, D., Spencer, C., Spiegel, L., Spitznagle, J., Srinivasalu, H., Stapp, H., Steigerwald, K., Stephens, A., Sterba Rakovchik, Y., Stern, S., Stevens, B., Stevenson, R., Stewart, K., Stewart, W., Stingl, C., Stoll, M., Stringer, E., Sule, S., Sullivan, J., Sundel, R., Sutter, M., Swaffar, C., Swayne, N., Syed, R., Symington, T., Syverson, G., Szymanski, A., Taber, S., Tal, R., Tambralli, A., Taneja, A., Tanner, T., Tarvin, S., Tate, L., Taxter, A., Taylor, J., Tesher, M., Thakurdeen, T., Theisen, A., Thomas, B., Thomas, L., Thomas, N., Ting, T., Todd, C., Toib, D., Torok, K., Tory, H., Toth, M., Tse, S., Tsin, C., Twachtman-Bassett, J., Twilt, M., Valcarcel, T., Valdovinos, R., Vallee, A., Van Mater, H., Vandenbergen, S., Vannoy, L., Varghese, C., Vasquez, N., Vega-Fernandez, P., Velez, J., Verbsky, J., Verstegen, R., von Scheven, E., Vora, S., Wagner-Weiner, L., Wahezi, D., Waite, H., Walker, B., Walters, H., Waterfield, M., Waters, A., Weiser, P., Weiss, P., Weiss, J., Wershba, E., Westheuser, V., White, A., Widrick, K., Williams, C., Wong, S., Woolnough, L., Wright, T., Wu, E., Yalcindag, A., Yasin, S., Yeung, R., Yomogida, K., Zeft, A., Zhang, Y., Zhao, Y., Zhu, A., Saper, Vivian E., Tian, Lu, Verstegen, Ruud H.J., Conrad, Carol K., Cidon, Michal, Hopper, Rachel K., Kuo, Christin S., Osoegawa, Kazutoyo, Baszis, Kevin, Bingham, Catherine A., Ferguson, Ian, Hahn, Timothy, Horne, Annacarin, Isupova, Eugenia A., Jones, Jordan T., Kasapcopur, Özgür, Klein-Gitelman, Marisa S., Kostik, Mikhail M., Ozen, Seza, Phadke, Omkar, Prahalad, Sampath, Randell, Rachel L., Sener, Seher, Stingl, Cory, Abdul-Aziz, Rabheh, Akoghlanian, Shoghik, Al Julandani, Dalila, Alvarez, Marcela B., Bader-Meunier, Brigitte, Balay-Dustrude, Erin E., Balboni, Imelda, Baxter, Sarah K., Berard, Roberta A., Bhattad, Sagar, Bolaria, Roxana, Boneparth, Alexis, Cassidy, Elaine A., Co, Dominic O., Collins, Kathleen P., Dancey, Paul, Dickinson, Aileen M., Edelheit, Barbara S., Espada, Graciela, Flanagan, Elaine R., Imundo, Lisa F., Jindal, Ankur K., Kim, Hyoun-Ah, Klaus, Günter, Lake, Carol, Lapin, W. Blaine, Lawson, Erica F., Marmor, Itay, Mombourquette, Joy, Ogunjimi, Benson, Olveda, Rebecca, Ombrello, Michael J., Onel, Karen, Poholek, Catherine, Ramanan, Athimalaipet V., Ravelli, Angelo, Reinhardt, Adam, Robinson, Amanda D., Rouster-Stevens, Kelly, Saad, Nadine, Schneider, Rayfel, Selmanovic, Velma, Sefic Pasic, Irmina, Shenoi, Susan, Shilo, Natalie R., Soep, Jennifer B., Sura, Angeli, Taber, Sarah F., Tesher, Melissa, Tibaldi, Jessica, Torok, Kathryn S., Tsin, Cathy Mei, Vasquez-Canizares, Natalia, Villacis Nunez, Diana S., Way, Emily E., Whitehead, Benjamin, Zemel, Lawrence S., Sharma, Surbhi, Fernández-Viña, Marcelo A., Mellins, Elizabeth D.

Source: In The Journal of Allergy and Clinical Immunology: In Practice November 2024 12(11):2996-3013

Examining the feasibility of data-driven decision support for the virtual crossmatch for solid organ transplantation: A single center study

Authors: Thapa, Isha, Lee, Raymond Ye, Fernandez Vina, Marcelo, Zhang, Bing Melody, Ahmed, Humera, Shin, Andrew Y, Bambos, Nicholas, Rosenthal, David N, Scheinker, David

Source: In Transplantation Reports September 2023 8(3)

Current HLA testing recommendations to support HCT

Authors: Yu, Neng, Askar, Medhat, Wadsworth, Kim, Gragert, Loren, Fernández-Viña, Marcelo A.

Source: In Human Immunology October 2022 83(10):665-673

HLA allele and haplotype frequencies of eight Indian populations based on 130,518 registered stem cell donors.

Authors: Solloch, Ute V., Kaniyath Madhusoodhanan, Chinma, Lange, Vinzenz, Sauter, Jürgen, Jagannathan, Latha, Paul, Patrick, Fernández-Viña, Marcelo A., Schmidt, Alexander H.

Source: Frontiers in Immunology; 2025, p1-22, 22p

State Laws Governing Syringe Services Programs and Participant Syringe Possession, 2014-2019

Authors: Fernández-Viña, Marcelo H., Prood, Nadya E., Herpolsheimer, Adam, Waimberg, Joshua, Burris, Scott

Source: Public Health Reports (1974-), 2020 Jul 01. 135(1S), 128S-137S.

Access URL: https://www.jstor.org/stable/26990671

Challenges for the standardized reporting of NGS HLA genotyping: Surveying gaps between clinical and research laboratories

Authors: Osoegawa, Kazutoyo, Montero-Martín, Gonzalo, Mallempati, Kalyan C., Bauer, Miranda, Milius, Robert P., Maiers, Martin, Fernández-Viña, Marcelo A., Mack, Steven J.

Source: In Human Immunology November 2021 82(11):820-828

High-resolution HLA allele and haplotype frequencies in several unrelated populations determined by next generation sequencing: 17th International HLA and Immunogenetics Workshop joint report

Authors: Creary, Lisa E., Sacchi, Nicoletta, Mazzocco, Michela, Morris, Gerald P., Montero-Martin, Gonzalo, Chong, Winnie, Brown, Colin J., Dinou, Amalia, Stavropoulos-Giokas, Catherine, Gorodezky, Clara, Narayan, Saranya, Periathiruvadi, Srinivasan, Thomas, Rasmi, De Santis, Dianne, Pepperall, Jennifer, ElGhazali, Gehad E., Al Yafei, Zain, Askar, Medhat, Tyagi, Shweta, Kanga, Uma, Marino, Susana R., Planelles, Dolores, Chang, Chia-Jung, Fernández-Viña, Marcelo A.

Source: In Human Immunology July 2021 82(7):505-522

Three Fields Allelic Haplotype Frequencies of HLA‐DPA1 and ‐DPB1 Typed by Next Generation Sequencing of 563 Families in Chinese Han Population.

Authors: Wang, Jian‐Ling, He, Jun‐Bo, Li, Zhi‐Min, Zhu, Ya‐Nan, Cao, DaJiang, Fu, Hong‐Lei, Zhang, Xian, Fernández‐Viña, Marcelo A., Rozemuller, Erik, Liu, XiangJun

Source: HLA: Immune Response Genetics; Dec2024, Vol. 104 Issue 6, p1-12, 12p

Subject Terms: HEMATOPOIETIC stem cell transplantation, NUCLEOTIDE sequencing, CHINESE people, HAPLOTYPES, NUCLEAR families

Curating Genetic Associations With Rheumatologic Autoimmune Diseases to Improve Patient Outcomes.

Authors: Bridges, S. Louis, Shapira, Rachel, Aksentijevich, Ivona, Mack, Steven J., Merriman, Tony R., Klein, Clarissa J., Bowen, B. Monica, Klein, Teri E., Ainsworth, Hannah C., Langefeld, Carl D., de Jesus, Adriana A., Deuitch, Natalie T., Ombrello, Michael J., Fernandez‐Ruiz, Ruth, Fernández‐Viña, Marcelo, Keseler, Ingrid M., Wright, Matt W., Lakhanpal, Amit, Laufer, Vincent A., Varga, John

Source: Arthritis & Rheumatology; Nov2024, Vol. 76 Issue 11, p1577-1581, 5p

Subject Terms: RHEUMATISM diagnosis, GENETICS of autoimmune diseases, PROTEINS, TREATMENT effectiveness, CONSORTIA, GENETIC mutation, ACCURACY, RHEUMATISM, GENETICS, GENETIC testing, HLA-B27 antigen, PHENOTYPES, ALLELES, COMMITTEES, GROUP process, SYMPTOMS

A specific amino acid motif of HLA-DRB1 mediates risk and interacts with smoking history in Parkinson’s disease

Authors: Hollenbach, Jill A., Norman, Paul J., Creary, Lisa E., Damotte, Vincent, Montero-Martin, Gonzalo, Caillier, Stacy, Anderson, Kirsten M., Misra, Maneesh K., Nemat-Gorgani, Neda, Osoegawa, Kazutoyo, Santaniello, Adam, Renschen, Adam, Marin, Wesley M., Dandekar, Ravi, Parham, Peter, Tanner, Caroline M., Hauser, Stephen L., Fernandez-Viña, Marcelo, Oksenberg, Jorge R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Apr 01. 116(15), 7419-7424.

Access URL: https://www.jstor.org/stable/26701399

Specific Class I HLA Supertypes but Not HLA Zygosity or Expression Are Associated with Outcomes following HLA-Matched Allogeneic Hematopoietic Cell Transplant: HLA Supertypes Impact Allogeneic HCT Outcomes

Authors: Camacho-Bydume, Christine, Wang, Tao, Sees, Jennifer A., Fernandez-Viña, Marcelo, Abid, Muhammad Bilal, Askar, Medhat, Beitinjaneh, Amer, Brown, Valerie, Castillo, Paul, Chhabra, Saurabh, Gadalla, Shahinaz M., Hsu, Jing-Mei, Kamoun, Malek, Lazaryan, Aleksandr, Nishihori, Taiga, Page, Kristin, Schetelig, Johannes, Fleischhauer, Katharina, Marsh, Steven G.E., Paczesny, Sophie, Spellman, Stephen R., Lee, Stephanie J., Hsu, Katharine C.

Source: In Biology of Blood and Marrow Transplantation October 2020

Urgent Time to Allogeneic Hematopoietic Cell Transplantation: A National Survey of Transplant Physicians and Unrelated Donor Search Coordinators Facilitated by the Histocompatibility Advisory Group to the National Marrow Donor Program

Authors: Pidala, Joseph, Mupfudze, Tatenda G., Payton, Tammy, Barker, Juliet, Perales, Miguel-Angel, Shaw, Bronwen E., Fernández-Viña, Marcelo, Burns, Linda J., Dehn, Jason

Source: In Biology of Blood and Marrow Transplantation December 2019 25(12):2501-2506

HLA Haplotypes In 250 Families: The Baylor Laboratory Results And A Perspective On A Core NGS Testing Model For The 17th International HLA And Immunogenetics Workshop

Authors: Askar, Medhat, Madbouly, Abeer, Zhrebker, Leah, Willis, Amanda, Kennedy, Shawna, Padros, Karin, Rodriguez, Maria Beatriz, Bach, Christian, Spriewald, Bernd, Ameen, Reem, Shemmari, Salem Al, Tarassi, Katerina, Tsirogianni, Alexandra, Hamdy, Nayera, Mossallam, Ghada, Hönger, Gideon, Spinnler, Regina, Fischer, Gottfried, Fae, Ingrid, Charlton, Ronald, Dunk, Arthur, Vayntrub, Tamara A., Halagan, Michael, Osoegawa, Kazutoyo, Fernández-Viña, Marcelo

Source: In Human Immunology November 2019 80(11):897-905

Next-generation sequencing reveals new information about HLA allele and haplotype diversity in a large European American population

Authors: Creary, Lisa E., Gangavarapu, Sridevi, Mallempati, Kalyan C., Montero-Martín, Gonzalo, Caillier, Stacy J., Santaniello, Adam, Hollenbach, Jill A., Oksenberg, Jorge R., Fernández-Viña, Marcelo A.

Source: In Human Immunology October 2019 80(10):807-822

17th IHIW component “Immunogenetics of Ageing” – New NGS data

Authors: Ivanova, Milena, Creary, Lisa E., Al Hadra, Bushra, Lukanov, Tsvetelin, Mazzocco, Michela, Sacchi, Nicoletta, Ameen, Reem, Al-Shemmari, Salem, Moise, Ana, Ursu, Larisa Denisa, Constantinescu, Ileana, Vayntrub, Tamara, Fernández-Viňa, Marcelo A., Shivarov, Velizar, Naumova, Elissaveta

Source: In Human Immunology September 2019 80(9):703-713

HLA alleles and haplotypes observed in 263 US families

Authors: Osoegawa, Kazutoyo, Mallempati, Kalyan C., Gangavarapu, Sridevi, Oki, Arisa, Gendzekhadze, Ketevan, Marino, Susana R., Brown, Nicholas K., Bettinotti, Maria P., Weimer, Eric T., Montero-Martín, Gonzalo, Creary, Lisa E., Vayntrub, Tamara A., Chang, Chia-Jung, Askar, Medhat, Mack, Steven J., Fernández-Viña, Marcelo A.

Source: In Human Immunology September 2019 80(9):644-660

Tools for building, analyzing and evaluating HLA haplotypes from families

Authors: Osoegawa, Kazutoyo, Mack, Steven J., Prestegaard, Matthew, Fernández-Viña, Marcelo A.

Source: In Human Immunology September 2019 80(9):633-643

Next-generation HLA typing of 382 International Histocompatibility Working Group reference B-lymphoblastoid cell lines: Report from the 17th International HLA and Immunogenetics Workshop

Authors: Creary, Lisa E., Guerra, Sandra G., Chong, Winnie, Brown, Colin J., Turner, Thomas R., Robinson, James, Bultitude, Will P., Mayor, Neema P., Marsh, Steven G.E., Saito, Katsuyuki, Lam, Kevin, Duke, Jamie L., Mosbruger, Timothy L., Ferriola, Deborah, Monos, Dimitrios, Willis, Amanda, Askar, Medhat, Fischer, Gottfried, Saw, Chee Loong, Ragoussis, Jiannis, Petrek, Martin, Serra-Pagés, Carles, Juan, Manel, Stavropoulos-Giokas, Catherine, Dinou, Amalia, Ameen, Reem, Al Shemmari, Salem, Spierings, Eric, Gendzekhadze, Ketevan, Morris, Gerald P., Zhang, Qiuheng, Kashi, Zahra, Hsu, Susan, Gangavarapu, Sridevi, Mallempati, Kalyan C., Yamamoto, Fumiko, Osoegawa, Kazutoyo, Vayntrub, Tamara, Chang, Chia-Jung, Hansen, John A., Fernández-Viňa, Marcelo A.

Source: In Human Immunology July 2019 80(7):449-460