Development and Bioavailability Assessment of an Estriol-Containing Vaginal Hydrogel

Authors: Peter Takacs, Barbara Kozma, Dávid Rátonyi, Bence Kozma, Kiss-Szikszai Attila, Ferenc Fenyvesi, Attila G. Sipos

Source: Gels, Vol 10, Iss 12, p 823 (2024)

Subject Terms: genitourinary syndrome of menopause (GSM), estriol-containing vaginal gel, hydroxyethyl cellulose (HEC), hydroxypropyl-β-cyclodextrin (HPBCD), estriol, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65

File Description: electronic resource

Relation: https://www.mdpi.com/2310-2861/10/12/823; https://doaj.org/toc/2310-2861

Access URL: https://doaj.org/article/d03980f0a8874106b3b72469648bb159

Synthesis and Biological Profiling of Seven Heparin and Heparan Sulphate Analogue Trisaccharides

Authors: Fruzsina Demeter, Zsófia Peleskei, Katalin Kútvölgyi, Ágnes Rusznyák, Ferenc Fenyvesi, Richárd Kajtár, Éva Sipos, István Lekli, Petra Molnár, Attila Gábor Szöllősi, Erika Lisztes, Balázs István Tóth, Anikó Borbás, Mihály Herczeg

Source: Biomolecules, Vol 14, Iss 9, p 1052 (2024)

Subject Terms: heparin, heparan sulphate, trisaccharides, anti-inflammatory, antioxidant, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/14/9/1052; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/cdfd29fab64f468cbfc78581f2c6b5b5

Chrysin-based supramolecular cyclodextrin-calixarene drug delivery system: a novel approach for attenuating cardiac fibrosis in chronic diabetes

Authors: Maria Consiglia Trotta, Hildegard Herman, Alina Ciceu, Bianca Mladin, Marcel Rosu, Caterina Claudia Lepre, Marina Russo, Ildikó Bácskay, Ferenc Fenyvesi, Raffaele Marfella, Anca Hermenean, Cornel Balta, Michele D’Amico

Source: Frontiers in Pharmacology, Vol 14 (2023)

Subject Terms: chrysin, cyclodextrin, calixarene, drug delivery system, cardiac fibrosis, chronic diabetes, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2023.1332212/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/b74f6094b38c49a8a099b5acfe9066ee

Synthesis of an amphiphilic vancomycin aglycone derivative inspired by polymyxins: overcoming glycopeptide resistance in Gram-positive and Gram-negative bacteria in synergy with teicoplanin in vitro

Authors: Zsolt Szűcs, Ilona Bereczki, Ferenc Fenyvesi, Pál Herczegh, Eszter Ostorházi, Anikó Borbás

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/56654604adc14062ac8524ad541391e1

Chrysin Directing an Enhanced Solubility through the Formation of a Supramolecular Cyclodextrin–Calixarene Drug Delivery System: A Potential Strategy in Antifibrotic Diabetes Therapeutics

Authors: Anca Hermenean, Eleftheria Dossi, Alex Hamilton, Maria Consiglia Trotta, Marina Russo, Caterina Claudia Lepre, Csilla Sajtos, Ágnes Rusznyák, Judit Váradi, Ildikó Bácskay, István Budai, Michele D’Amico, Ferenc Fenyvesi

Source: Pharmaceuticals, Vol 17, Iss 1, p 107 (2024)

Subject Terms: OTX008, chrysin, sulfobutylated β-cyclodextrin, ternary complex, solubilization mechanism, molecular simulation, Medicine, Pharmacy and materia medica, RS1-441

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Relation: https://www.mdpi.com/1424-8247/17/1/107; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/172a0383479449af9dbed3ac68dad0de

Concentration-Dependent Antibacterial Activity of Chitosan on Lactobacillus plantarum

Authors: Renátó Kovács, Lóránd Erdélyi, Ferenc Fenyvesi, Noémi Balla, Fruzsina Kovács, György Vámosi, Ágnes Klusóczki, Alexandra Gyöngyösi, Ildikó Bácskay, Miklós Vecsernyés, Judit Váradi

Source: Pharmaceutics, Vol 15, Iss 1, p 18 (2022)

Subject Terms: chitosan, Lactobacillus, antibacterial, interaction, time-kill, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/1/18; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/6d87925f035d491ab9fbc9200515c022

Effects of Hydroxypropyl-Beta-Cyclodextrin on Cultured Brain Endothelial Cells

Authors: Szilvia Veszelka, Mária Mészáros, Gergő Porkoláb, Ágnes Rusznyák, Katalin Szászné Réti-Nagy, Mária A. Deli, Miklós Vecsernyés, Ildikó Bácskay, Judit Váradi, Ferenc Fenyvesi

Source: Molecules, Vol 27, Iss 22, p 7738 (2022)

Subject Terms: blood–brain barrier, 2-hydroxypropyl-beta-cyclodextrin, endocytosis, Niemann–Pick disease, type C, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/22/7738; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/0e5c0c8bdb8e4b0a86efb4bf20f686a1

Enhanced Antioxidant and Anti-Inflammatory Effects of Self-Nano and Microemulsifying Drug Delivery Systems Containing Curcumin

Authors: Liza Józsa, Gábor Vasvári, Dávid Sinka, Dániel Nemes, Zoltan Ujhelyi, Miklós Vecsernyés, Judit Váradi, Ferenc Fenyvesi, István Lekli, Alexandra Gyöngyösi, Ildikó Bácskay, Pálma Fehér

Source: Molecules, Vol 27, Iss 19, p 6652 (2022)

Subject Terms: curcumin, self-emulsifying systems, drug delivery, anti-inflammatory effect, antioxidant effect, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/19/6652; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/b72424894ac141648bb54fcb6c8a2fe8

Enhanced Expression of Human Epididymis Protein 4 (HE4) Reflecting Pro-Inflammatory Status Is Regulated by CFTR in Cystic Fibrosis Bronchial Epithelial Cells

Authors: Zsolt Bene, Zsolt Fejes, Tibor Gabor Szanto, Ferenc Fenyvesi, Judit Váradi, Luka A. Clarke, Gyorgy Panyi, Milan Macek, Margarida D. Amaral, István Balogh, Béla Nagy

Source: Frontiers in Pharmacology, Vol 12 (2021)

Subject Terms: cystic fibrosis, inflammation, bronchial epithelial cell, HE4, CFTR modulator, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.592184/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/77715d92d7524ce09a90bf902985221f

Platelet Microparticles Enriched in miR-223 Reduce ICAM-1-Dependent Vascular Inflammation in Septic Conditions

Authors: Bernadett Szilágyi, Zsolt Fejes, Ágnes Rusznyák, Ferenc Fenyvesi, Marianna Pócsi, Sándor Halmi, Zoltán Griger, Satya P. Kunapuli, János Kappelmayer, Béla Nagy

Source: Frontiers in Physiology, Vol 12 (2021)

Subject Terms: platelet, endothelial cell, microRNA, miR-223, sepsis, microparticle, Physiology, QP1-981

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphys.2021.658524/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/1b2ff5de07434f50817365708c199e5d

Stability, Permeability and Cytotoxicity of Buccal Films in Allergy Treatment

Authors: Krisztián Pamlényi, Géza Regdon, Dániel Nemes, Ferenc Fenyvesi, Ildikó Bácskay, Katalin Kristó

Source: Pharmaceutics, Vol 14, Iss 8, p 1633 (2022)

Subject Terms: mucoadhesive, buccal films, drug delivery, alginate, cetirizine, antihistamine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/14/8/1633; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/fc839fa2c1114ba88696d5a70760008e

Investigation of the Drug Carrier Properties of Insoluble Cyclodextrin Polymer Microspheres

Authors: Ádám Haimhoffer, Alexandra Vas, Gabriella Árvai, Éva Fenyvesi, László Jicsinszky, István Budai, Attila Bényei, Géza Regdon, Ágnes Rusznyák, Gábor Vasvári, Judit Váradi, Ildikó Bácskay, Miklós Vecsernyés, Ferenc Fenyvesi

Source: Biomolecules, Vol 12, Iss 7, p 931 (2022)

Subject Terms: insoluble cyclodextrin polymer, cyclodextrin beads, curcumin, estradiol-glow, complexation, drug delivery, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/12/7/931; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/0488231d8a154440880707447dd72f68

Effects of the Calix[4]arene Derivative Compound OTX008 on High Glucose-Stimulated ARPE-19 Cells: Focus on Galectin-1/TGF-β/EMT Pathway

Authors: Maria Consiglia Trotta, Francesco Petrillo, Carlo Gesualdo, Settimio Rossi, Alberto Della Corte, Judit Váradi, Ferenc Fenyvesi, Michele D’Amico, Anca Hermenean

Source: Molecules, Vol 27, Iss 15, p 4785 (2022)

Subject Terms: diabetic retinopathy, retinal pigment epithelial cells, galectin-1, OTX008, fibrosis, epithelial-mesenchymal transition, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/15/4785; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/d3e4be0181bc4512aa6c567f2aa25e24

Formulation, Characterization and Permeability Studies of Fenugreek (Trigonella foenum-graecum) Containing Self-Emulsifying Drug Delivery System (SEDDS)

Authors: Dávid Sinka, Enikő Doma, Nóra Szendi, Jázmin Páll, Dóra Kósa, Ágota Pető, Pálma Fehér, Zoltán Ujhelyi, Ferenc Fenyvesi, Judit Váradi, Miklós Vecsernyés, Zsolt Szűcs, Sándor Gonda, Zoltán Cziáky, Attila Kiss-Szikszai, Gábor Vasas, Ildikó Bácskay

Source: Molecules, Vol 27, Iss 9, p 2846 (2022)

Subject Terms: fenugreek, trigonella foenum-graecum, SEDDS, permeability assay, cytotoxicity, dissolution test, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/9/2846; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/8512486d0b264ce09dd6eb38432045e2

Topical Dosage Formulation of Lyophilized Philadelphus coronarius L. Leaf and Flower: Antimicrobial, Antioxidant and Anti-Inflammatory Assessment of the Plant

Authors: Ágota Pető, Dóra Kósa, Ádám Haimhoffer, Dániel Nemes, Pálma Fehér, Zoltán Ujhelyi, Miklós Vecsernyés, Judit Váradi, Ferenc Fenyvesi, Adina Frum, Felicia Gabriela Gligor, Laura Grațiela Vicaș, Eleonora Marian, Tunde Jurca, Annamaria Pallag, Mariana Eugenia Muresan, Zoltán Tóth, Ildikó Bácskay

Source: Molecules, Vol 27, Iss 9, p 2652 (2022)

Subject Terms: Philadelphus coronarius, chemical compounds, penetration enhancers, cytotoxicity, ointments, topical application, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/9/2652; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/fa4eee62e962445cafbdb95b5fd3ca9b

In Vitro and In Vivo Studies of a Verapamil-Containing Gastroretentive Solid Foam Capsule

Authors: Ádám Haimhoffer, Gábor Vasvári, István Budai, Monika Béresová, Ádám Deák, Norbert Németh, Judit Váradi, Dávid Sinka, Ildikó Bácskay, Miklós Vecsernyés, Ferenc Fenyvesi

Source: Pharmaceutics, Vol 14, Iss 2, p 350 (2022)

Subject Terms: solid foam, gastric retention, verapamil, continuous production, pharmacokinetic study, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/14/2/350; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/72edc181fc1643558aceae4c6719a182

Cellular Effects of Cyclodextrins: Studies on HeLa Cells

Authors: Ágnes Rusznyák, Mercédesz Palicskó, Milo Malanga, Éva Fenyvesi, Lajos Szente, Judit Váradi, Ildikó Bácskay, Miklós Vecsernyés, Katalin Szászné Réti-Nagy, Gábor Vasvári, Ádám Haimhoffer, Ferenc Fenyvesi

Source: Molecules, Vol 27, Iss 5, p 1589 (2022)

Subject Terms: HPBCD, RAMEB, endocytosis, lysosomes, autophagy, NF-κB, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/27/5/1589; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/6afc9334d1834ab9bf4988ba85e5c525

Oral Bioavailability Enhancement of Melanin Concentrating Hormone, Development and In Vitro Pharmaceutical Assessment of Novel Delivery Systems

Authors: Dóra Kósa, Ágota Pető, Ferenc Fenyvesi, Judit Váradi, Miklós Vecsernyés, István Budai, József Németh, Pálma Fehér, Ildikó Bácskay, Zoltán Ujhelyi

Source: Pharmaceutics, Vol 14, Iss 1, p 9 (2021)

Subject Terms: peptide carriers, bioavailability, alginate beads, penetration enhancers, biocompatibility investigation, MTT test, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/14/1/9; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/7822d265aa204515986864603d2edbf7

Physico-Chemical, In Vitro and Ex Vivo Characterization of Meloxicam Potassium-Cyclodextrin Nanospheres

Authors: Patrícia Varga, Rita Ambrus, Piroska Szabó-Révész, Dávid Kókai, Katalin Burián, Zsolt Bella, Ferenc Fenyvesi, Csilla Bartos

Source: Pharmaceutics, Vol 13, Iss 11, p 1883 (2021)

Subject Terms: alpha-cyclodextrin, hydroxypropyl-β-cyclodextrin, meloxicam potassium, nano spray drying, nasal drug delivery, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/13/11/1883; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/a636b8b967564a81af59f22f546de9bf

Nicotinic Amidoxime Derivate BGP-15, Topical Dosage Formulation and Anti-Inflammatory Effect

Authors: Ágota Pető, Dóra Kósa, Ádám Haimhoffer, Pálma Fehér, Zoltán Ujhelyi, Dávid Sinka, Ferenc Fenyvesi, Judit Váradi, Miklós Vecsernyés, Alexandra Gyöngyösi, István Lekli, Péter Szentesi, Annamária Marton, Imre Gombos, Barbara Dukic, László Vígh, Ildikó Bácskay

Source: Pharmaceutics, Vol 13, Iss 12, p 2037 (2021)

Subject Terms: nicotinic amidoxime derivate, BGP-15, ointments, surfactants, anti-inflammatory drug, drug delivery, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/13/12/2037; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/35559a9408cd4affa8c6bf413979279b