Tailoring implementation strategies for the healthy actions and lifestyles to Avoid Dementia or Hispanos y el ALTo a la Demencia Program: Lessons learned from a survey study

Authors: Moukarzel, Sara ^{a, b}, Araujo-Menendez, Carlos E.E. ^c, Galang, Eliza ^b, Zlatar, Zvinka Z. ^d, Feldman, Howard H. ^{a, b}, Banks, Sarah J. ^{a, d, ⁎}

Source: In The Journal of Prevention of Alzheimer's Disease March 2025 12(3)

Use of lecanemab and donanemab in the Canadian healthcare system: Evidence, challenges, and areas for future research

Authors: Smith, Eric E. ^{a, ⁎}, Phillips, Natalie A. ^b, Feldman, Howard H. ^c, Borrie, Michael ^d, Ganesh, Aravind ^a, Henri-Bhargava, Alexandre ^e, Desmarais, Philippe ^f, Frank, Andrew ^g, Badhwar, AmanPreet ^h, Barlow, Laura ⁱ, Bartha, Robert ^d, Best, Sarah ^d, Bethell, Jennifer ^j, Bhangu, Jaspreet ^d, Black, Sandra E. ^k, Bocti, Christian ^l, Bronskill, Susan E. ^m, Burhan, Amer M. ⁿ, Calon, Frederic ^o, Camicioli, Richard ^p, Campbell, Barry ^q, Collins, D. Louis ^r, Dadar, Mahsa ^r, DeMarco, Mari L. ^s, Ducharme, Simon ^t, Duchesne, Simon ^u, Einstein, Gillian ^v, Fisk, John D. ^w, Gawryluk, Jodie R. ^x, Grossman, Linda ^z, Ismail, Zahinoor ^a, Itzhak, Inbal ^y, Joshi, Manish ^a, Harrison, Arthur ^z, Kröger, Edeltraut ^aa, Kumar, Sanjeev ^v, Laforce, Robert ^u, Lanctot, Krista L. ^ab, Lau, Meghan ^z, Lee, Linda ^ac, Masellis, Mario ^ad, Massoud, Fadi ^ae, Mitchell, Sara B. ^v, Montero-Odasso, Manuel ^aj, Myers Barnett, Karen ^z, Nygaard, Haakon B. ⁱ, Pasternak, Stephen H. ^af, Peters, Jody ^z, Rajah, M. Natasha ^ag, Robillard, Julie M. ⁱ, Rockwood, Ken ^w, Rosa-Neto, Pedro ^r, Seitz, Dallas P. ^a, Soucy, Jean-Paul ^r, Trenaman, Shanna C. ^ah, Wellington, Cheryl L. ^ak, Zadem, Aicha ^l, Chertkow, Howard ^ai

Source: In The Journal of Prevention of Alzheimer's Disease March 2025 12(3)

Efficacy assessment of an active tau immunotherapy in Alzheimer’s disease patients with amyloid and tau pathology: a post hoc analysis of the “ADAMANT” randomised, placebo-controlled, double-blind, multi-centre, phase 2 clinical trial

Authors: Cullen, Nicholas C. ^a, Novak, Petr ^{b, ∗}, Tosun, Duygu ^{c, d}, Kovacech, Branislav ^e, Hanes, Jozef ^e, Kontsekova, Eva ^e, Fresser, Michal ^f, Ropele, Stefan ^g, Feldman, Howard H. ^h, Schmidt, Reinhold ⁱ, Winblad, Bengt ^j, Zilka, Norbert ^e

Source: In eBioMedicine January 2024 99

Exploring Social Cognition Tests to Differentiate Frontotemporal Dementia from Depression

Authors: Lichtenstein, Maya L., Stewart, Peter V., Kirchner, H. Lester, Finney, Glen, Feldman, Howard H.

Source: Alzheimer disease and associated disorders. 37(2):145-148

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191130540.0x000001&indx=1&recIds=ETOCvdc_100191130540.0x000001

Nutritional metabolism and cerebral bioenergetics in Alzheimer's disease and related dementias

Authors: Yassine, Hussein N., Self, Wade, Kerman, Bilal E., Santoni, Giulia, Navalpur Shanmugam, NandaKumar, Abdullah, Laila, Golden, Lesley R., Fonteh, Alfred N., Harrington, Michael G., Gräff, Johannes, Gibson, Gary E., Kalaria, Raj, Luchsinger, Jose A., Feldman, Howard H., Swerdlow, Russell H., Johnson, Lance A., Albensi, Benedict C., Zlokovic, Berislav V., Tanzi, Rudolph, Cunnane, Stephen, Samieri, Cécilia, Scarmeas, Nikolaos, Bowman, Gene L.

Source: Alzheimer's & dementia. 19(3):1041-1066

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178048737.0x000001&indx=1&recIds=ETOCvdc_100178048737.0x000001

Protocol for a seamless phase 2A-phase 2B randomized double-blind placebo-controlled trial to evaluate the safety and efficacy of benfotiamine in patients with early Alzheimer's disease (BenfoTeam).

Authors: Feldman, Howard H.^1,2,3 (AUTHOR) howardfeldman@health.ucsd.edu, Luchsinger, José A.⁴ (AUTHOR), Léger, Gabriel C.^1,2 (AUTHOR), Taylor, Curtis^1,2 (AUTHOR), Jacobs, Diane M.^1,2,3 (AUTHOR), Salmon, David P.^1,2,3 (AUTHOR), Edland, Steven D.^1,2,3 (AUTHOR), Messer, Karen^1,2 (AUTHOR), Revta, Carolyn^1,2 (AUTHOR), Flowers, Sarah A.⁵ (AUTHOR), Jones, Kerry S.⁶ (AUTHOR), Koulman, Albert⁶ (AUTHOR), Yarasheski, Kevin E.⁷ (AUTHOR), Verghese, Philip B.⁷ (AUTHOR), Venkatesh, Venky⁷ (AUTHOR), Zetterberg, Henrik^{8,9,10,11,12,13} (AUTHOR), Durant, January^1,2 (AUTHOR), Lupo, Jody-Lynn^1,2 (AUTHOR), Gibson, Gary E.¹⁴ (AUTHOR)

Source: PLoS ONE. 5/29/2024, Vol. 19 Issue 5, p1-17. 17p.

Subject Terms: *VITAMIN B1, *ALZHEIMER'S patients, *ALZHEIMER'S disease

A Matter for Life and Death: Managing Psychological Trauma in Care Homes

Authors: Estabrooks, Carole A., Titley, Heather K., Thorne, Trina, Banerjee, Sube, Feldman, Howard H., Silvius, James, Lanius, Ruth A.

Source: Journal of the American Medical Directors Association. 23(7):1123-1126

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100166845134.0x000001&indx=1&recIds=ETOCvdc_100166845134.0x000001

Committee on High‐quality Alzheimer's Disease Studies (CHADS) consensus report

Authors: Jicha, Greg A., Abner, Erin L., Arnold, Steven E., Carrillo, Maria C., Dodge, Hiroko H., Edland, Steven D., Fargo, Keith N., Feldman, Howard H., Goldstein, Larry B., Hendrix, James, Peters, Ruth, Robillard, Julie M., Schneider, Lon S., Titiner, Jodi R., Weber, Christopher J.

Source: Alzheimer's & dementia. 18(6):1109-1118

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151699198.0x000001&indx=1&recIds=ETOCvdc_100151699198.0x000001

Current directions in tau research: Highlights from Tau 2020

Authors: Sexton, Claire, Snyder, Heather, Beher, Dirk, Boxer, Adam L., Brannelly, Pat, Brion, Jean‐Pierre, Buée, Luc, Cacace, Angela M., Chételat, Gaël, Citron, Martin, DeVos, Sarah L., Diaz, Kristophe, Feldman, Howard H., Frost, Bess, Goate, Alison M., Gold, Michael, Hyman, Bradley, Johnson, Keith, Karch, Celeste M., Kerwin, Diana R., Koroshetz, Walter J., Litvan, Irene, Morris, Huw R., Mummery, Catherine J., Mutamba, James, Patterson, Marc C., Quiroz, Yakeel T., Rabinovici, Gil D., Rommel, Amy, Shulman, Melanie B., Toledo‐Sherman, Leticia M., Weninger, Stacie, Wildsmith, Kristin R., Worley, Susan L., Carrillo, Maria C.

Source: Alzheimer's & dementia. 18(5):988-1007

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100149900113.0x000001&indx=1&recIds=ETOCvdc_100149900113.0x000001

Pharmacokinetic and pharmacodynamic assessment of oral nicotinamide in the NEAT clinical trial for early Alzheimer's disease.

Authors: Ketron, Gabriel L, Grun, Felix, Grill, Joshua D, Feldman, Howard H, Rissman, Robert A, Brewer, Gregory J

Source: Alzheimer's Research & Therapy; 3/11/2025, Vol. 17 Issue 1, p1-13, 13p

evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomatic Alzheimer's disease.

Authors: Cummings, Jeffrey L., Atri, Alireza, Feldman, Howard H., Hansson, Oskar, Sano, Mary, Knop, Filip K., Johannsen, Peter, León, Teresa, Scheltens, Philip

Source: Alzheimer's Research & Therapy; 1/8/2024, Vol. 17 Issue 1, p1-12, 12p

Subject Terms: GLUCAGON-like peptide-1 receptor, MILD cognitive impairment, CLINICAL trials, POSITRON emission tomography, ALZHEIMER'S disease

Clinical diagnosis of Alzheimer's disease: recommendations of the International Working Group

Authors: Dubois, Bruno ^{*, *}, Villain, Nicolas ^*, Frisoni, Giovanni B, Rabinovici, Gil D, Sabbagh, Marwan, Cappa, Stefano, Bejanin, Alexandre, Bombois, Stéphanie, Epelbaum, Stéphane, Teichmann, Marc, Habert, Marie-Odile, Nordberg, Agneta, Blennow, Kaj, Galasko, Douglas, Stern, Yaakov, Rowe, Christopher C, Salloway, Stephen, Schneider, Lon S, Cummings, Jeffrey L, Feldman, Howard H

Source: In The Lancet Neurology June 2021 20(6):484-496

Sleep and its regulation: An emerging pathogenic and treatment frontier in Alzheimer’s disease

Authors: Kent, Brianne A. ^*, Feldman, Howard H., Nygaard, Haakon B.

Source: In Progress in Neurobiology February 2021 197

Recruitment of a multi‐site randomized controlled trial of aerobic exercise for older adults with amnestic mild cognitive impairment: The EXERT trial

Authors: Shadyab, Aladdin H., LaCroix, Andrea Z., Feldman, Howard H., Dyck, Christopher H., Okonkwo, Ozioma C., Tam, Steven P., Fairchild, J. Kaci, Welsh‐Bohmer, Kathleen A., Matthews, Genevieve, Bennett, Daniel, Shadyab, Alexandre A., Schafer, Kimberly A., Morrison, Rosemary H., Kipperman, Sean A., Mason, Jennifer, Tan, Donna, Thomas, Ronald G., Cotman, Carl W., Baker, Laura D.

Source: Alzheimer's & dementia. 17(11):1808-1817

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100135791720.0x000001&indx=1&recIds=ETOCvdc_100135791720.0x000001

Brain volumetric deficits in MAPT mutation carriers: a multisite study

Authors: Chu, Stephanie A., Flagan, Taru M., Staffaroni, Adam M., Jiskoot, Lize C., Deng, Jersey, Spina, Salvatore, Zhang, Liwen, Sturm, Virginia E., Yokoyama, Jennifer S., Seeley, William W., Papma, Janne M., Geschwind, Dan H., Rosen, Howard J., Boeve, Bradley F., Boxer, Adam L., Heuer, Hilary W., Forsberg, Leah K., Brushaber, Danielle E., Grossman, Murray, Coppola, Giovanni, Dickerson, Bradford C., Bordelon, Yvette M., Faber, Kelley, Feldman, Howard H., Fields, Julie A., Fong, Jamie C., Foroud, Tatiana, Gavrilova, Ralitza H., Ghoshal, Nupur, Graff‐Radford, Neill R., Hsiung, Ging‐Yuek Robin, Huey, Edward D., Irwin, David J., Kantarci, Kejal, Kaufer, Daniel I., Karydas, Anna M., Knopman, David S., Kornak, John, Kramer, Joel H., Kukull, Walter A., Lapid, Maria I., Litvan, Irene, Mackenzie, Ian R.A., Mendez, Mario F., Miller, Bruce L., Onyike, Chiadi U., Pantelyat, Alexander Y., Rademakers, Rosa, Marisa Ramos, Eliana, Roberson, Erik D., Carmela Tartaglia, Maria, Tatton, Nadine A., Toga, Arthur W., Vetor, Ashley, Weintraub, Sandra, Wong, Bonnie, Wszolek, Zbigniew K., Van Swieten, John C., Lee, Suzee E.

Source: Annals of clinical and translational neurology. 8(1):95-110

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114687375.0x000001&indx=1&recIds=ETOCvdc_100114687375.0x000001

Engaging older adults in the process of aging research: a multimethod study evaluating the experience and efficacy of a citizen advisory group for a dementia risk reduction program.

Authors: D'Amico, Danielle, Savundranayagam, Marie Y., Biles, Rose, Itzhak, Inbal, Anderson, Nicole D., Chertkow, Howard, Belleville, Sylvie, Feldman, Howard H., Montero-Odasso, Manuel, Nygaard, Haakon, Anderson, Nicole, Banks, Sarah, Das, Samir, Evans, A. Carol, Ferland, Guylaine, Furlano, Joyla A., Hofer, Scott, Jacobs, Diane, Jarrett, Pamela, Lim, Andrew

Source: Research Involvement & Engagement; 12/27/2024, Vol. 10 Issue 1, p1-16, 16p

Subject Terms: SCHOLARLY method, SATISFACTION, OLDER people, RISK perception, DISEASE risk factors

Post hoc analysis of ADAMANT, a phase 2 clinical trial of active tau immunotherapy with AADvac1 in patients with Alzheimer's disease, positive for plasma p-tau217.

Authors: Kovacech, Branislav, Cullen, Nicholas C., Novak, Petr, Hanes, Jozef, Kontsekova, Eva, Katina, Stanislav, Parrak, Vojtech, Fresser, Michal, Vanbrabant, Jeroen, Feldman, Howard H., Winblad, Bengt, Stoops, Erik, Vanmechelen, Eugeen, Zilka, Norbert

Source: Alzheimer's Research & Therapy; 11/23/2024, Vol. 16 Issue 1, p1-14, 14p

Subject Terms: GLIAL fibrillary acidic protein, ALZHEIMER'S disease, ALZHEIMER'S patients, MILD cognitive impairment, CEREBRAL atrophy, IMMUNOTHERAPY

Varoglutamstat: Inhibiting Glutaminyl Cyclase as a Novel Target of Therapy in Early Alzheimer's Disease.

Authors: Feldman, Howard H.^1,2,3 (AUTHOR) howardfeldman@health.ucsd.edu, Messer, Karen^1,2 (AUTHOR), Qiu, Yuqi⁴ (AUTHOR), Sabbagh, Marwan⁵ (AUTHOR), Galasko, Douglas^1,2,3 (AUTHOR), Turner, R. Scott⁶ (AUTHOR), Lopez, Oscar^7,8 (AUTHOR), Smith, Amanda⁹ (AUTHOR), Durant, January^1,2 (AUTHOR), Lupo, Jody-Lynn^1,2 (AUTHOR), Revta, Carolyn^1,2 (AUTHOR), Balasubramanian, Archana^1,2 (AUTHOR), Kuehn-Wache, Kerstin¹⁰ (AUTHOR), Wassmann, Tanja¹⁰ (AUTHOR), Schell-Mader, Sylvia¹⁰ (AUTHOR), Jacobs, Diane M.^1,2,3 (AUTHOR), Salmon, David P.^1,2,3 (AUTHOR), Léger, Gabriel^1,2 (AUTHOR), DeMarco, Mari L.^11,12 (AUTHOR), Weber, Frank¹⁰ (AUTHOR)

Source: Journal of Alzheimer's Disease. 2024 Supplement 1, Vol. 101, pS79-S93. 15p.

Subject Terms: *ALZHEIMER'S disease, *MILD cognitive impairment, *COGNITIVE analysis, *CEREBROSPINAL fluid, *SMALL molecules

A framework for translating tauopathy therapeutics: Drug discovery to clinical trials.

Authors: Feldman, Howard H., Cummings, Jeffrey L., Boxer, Adam L., Staffaroni, Adam M., Knopman, David S., Sukoff Rizzo, Stacey J., Territo, Paul R., Arnold, Steven E., Ballard, Clive, Beher, Dirk, Boeve, Bradley F., Dacks, Penny A., Diaz, Kristophe, Ewen, Colin, Fiske, Brian, Gonzalez, M. Isabel, Harris, Glenn A., Hoffman, Beth J., Martinez, Terina N., McDade, Eric

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Nov2024, Vol. 20 Issue 11, p8129-8152, 24p

Challenges and Opportunities for Consideration of Efavirenz Drug Repurposing for Alzheimer's Disease Therapeutics.

Authors: Boyarko, Ben, Podvin, Sonia, Greenberg, Barry, Arnold, Steven, Juanes, Almudena Maroto, van der Kant, Rik, Goldstein, Lawrence, Momper, Jeremiah D., Bang, Anne, Silverman, James, Feldman, Howard H., Hook, Vivian

Source: ACS Pharmacology & Translational Science; 10/11/2024, Vol. 7 Issue 10, p2924-2935, 12p