The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner

Authors: Adriana Gonzalez-Sandoval, Katja Pekrun, Shinnosuke Tsuji, Feijie Zhang, King L. Hung, Howard Y. Chang, Mark A. Kay

Source: Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d62aaf6b8f6e41b794d5bf3b8b68ef81

Aptamer-programmable adeno-associated viral vectors as a novel platform for cell-specific gene transfer

Authors: Francesco Puzzo, Chuanling Zhang, Bethany Powell Gray, Feijie Zhang, Bruce A. Sullenger, Mark A. Kay

Source: Molecular Therapy: Nucleic Acids, Vol 31, Iss , Pp 383-397 (2023)

Subject Terms: MT: Delivery Strategies, adeno-associated virus, vector engineering, aptamers, gene therapy, precision medicine, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2162253123000100; https://doaj.org/toc/2162-2531

Access URL: https://doaj.org/article/2cb14785ab9043a29a90dad688519651

Selection of rAAV vectors that cross the human blood-brain barrier and target the central nervous system using a transwell model

Authors: Ren Song, Katja Pekrun, Themasap A. Khan, Feijie Zhang, Sergiu P. Paşca, Mark A. Kay

Source: Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 73-88 (2022)

Subject Terms: blood brain barrier, CNS capsids, transwell, human BBB, central nervous system, chimeric AAV vectors, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122001279; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/86db400fe64f437aa8bcb31f674ac266

miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression

Authors: Paul N. Valdmanis, Hak Kyun Kim, Kirk Chu, Feijie Zhang, Jianpeng Xu, Elizabeth M. Munding, Jia Shen, Mark A. Kay

Source: Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/bce2ee1a64f046a383d8e6d4a3be7c1a

Thermodynamic stability of small hairpin RNAs highly influences the loading process of different mammalian Argonautes.

Authors: Shuo Gu, Lan Jin, Feijie Zhang, Yong Huang, Grimm, Dirk, Rossi, John J., Kay, Mark A.

Source: Proceedings of the National Academy of Sciences of the United States of America; 5/31/2011, Vol. 108 Issue 22, p9208-9213, 6p

Subject Terms: MESSENGER RNA, SMALL interfering RNA, NUCLEOTIDE sequence, GENE expression, DROSOPHILA

Diesel Exhaust Particle-Exposed Human Bronchial Epithelial Cells Induce Dendritic Cell Maturation and Polarization via Thymic Stromal Lymphopoietin.

Authors: Bertram Bleck¹, Feijie Zhang¹

Source: Journal of Clinical Immunology. Mar2008, Vol. 28 Issue 2, p147-156. 10p.

Subject Terms: *AIR pollution, *ALLERGIES, *DENDRITIC cells, *DIESEL motor exhaust gas

Mechanical ventilation with 40% oxygen reduces pulmonary expression of genes that regulate lung development and impairs alveolar septation in newborn mice.

Authors: Bland, Richard D., Mokres, Lucia M., Ertsey, Robert, Jacobson, Berit E., Shu Jiang, Rabinovitch, Marlene, Liwen Xu, Shinwell, Eric S., Feijie Zhang, Beasley, Matthew A.

Source: American Journal of Physiology: Lung Cellular & Molecular Physiology; Nov2007, Vol. 293, pL1099-L1110, 11p, 8 Diagrams, 1 Chart

Subject Terms: ARTIFICIAL respiration, BRONCHOPULMONARY dysplasia, LUNG diseases, LABORATORY mice, CELL physiology, MESSENGER RNA, VASCULAR endothelial growth factors, TENASCIN

Expression of CINC-2β Is Related to the State of Differentiation of Alveolar Epithelial Cells.

Authors: Kahoru Nishina, Feijie Zhang, Nielsen, Larry D., Edeen, Karen, Jieru Wang, Mason, Robert J.

Source: American Journal of Respiratory Cell & Molecular Biology; 2005, Vol. 33 Issue 5, p505-512, 8p, 2 Black and White Photographs, 2 Charts, 4 Graphs

Transforming Growth Factor-β Antagonizes Alveolar Type II Cell Proliferation Induced by Keratinocyte Growth Factor.

Authors: Feijie Zhang, Nielsen, Larry D., Lucas, Joseph J., Mason, Robert J.

Source: American Journal of Respiratory Cell & Molecular Biology; 2004, Vol. 31 Issue 6, p679-686, 8p, 1 Diagram, 5 Graphs

Lipogenesis in Fetal Rat Lung.

Authors: Feijie Zhang, Pan, Tianli, Nielsen, Larry D., Mason, Robert J.

Source: American Journal of Respiratory Cell & Molecular Biology; 2004, Vol. 30 Issue 2, p174-183, 10p

Keratinocyte growth factor and the transcription factors C/EBPα, C/EBPδ, and SREBP-1c regulate fatty acid synthesis in alveolar type II cells.

Authors: Mason, Robert J., Tianli Pan, Edeen, Karen E., Nielsen, Larry D., Feijie Zhang, Longphre, Malinda, Eckart, Michael R., Neben, Steven

Source: Journal of Clinical Investigation. Jul2003, Vol. 112 Issue 2, p244. 12p.

Subjects: KERATINOCYTES, GROWTH factors, FATTY acids, PHOSPHOLIPIDS, CELLS