Thiosulphate sulfurtransferase: Biological roles and therapeutic potential

Authors: Luo, Yang ^{a, b, 1}, Melhem, Shaden ^{c, 1}, Feelisch, Martin ^d, Chatre, Laurent ^e, Morton, Nicholas M. ^f, Dolga, Amalia M. ^a, van Goor, Harry ^{b, ⁎}

Source: In Redox Biology May 2025 82

Bariatric surgery blunts nitrate-mediated improvements in cardiovascular function of overweight women by interfering with gastric S-nitrosothiol formation

Authors: Sanches-Lopes, Jéssica Maria, Cássia-Barros, Alessandra, Conde-Tella, Sandra Oliveira, Coelho, Eduardo Barbosa, Kemp, Rafael, Lacchini, Riccardo, Feelisch, Martin, Salgado Júnior, Wilson, Tanus-Santos, Jose Eduardo

Source: In Redox Biology December 2024 78

ALDH2 polymorphism and myocardial infarction: From alcohol metabolism to redox regulation

Authors: Lamb, Reece J., Griffiths, Kayleigh, Lip, Gregory Y.H., Sorokin, Vitaly, Frenneaux, Michael P., Feelisch, Martin, Madhani, Melanie

Source: In Pharmacology and Therapeutics July 2024 259

Perioperative oxygenation—what's the stress?

Authors: Larvin, Joseph, Edwards, Mark, Martin, Daniel S., Feelisch, Martin, Grocott, Michael P.W., Cumpstey, Andrew F.

Source: In BJA Open June 2024 10

Thiosulfate sulfurtransferase deficiency promotes oxidative distress and aberrant NRF2 function in the brain

Authors: Luo, Yang, Chatre, Laurent, Melhem, Shaden, Al-Dahmani, Zayana M., Homer, Natalie Z.M., Miedema, Anneke, Deelman, Leo E., Groves, Matthew R., Feelisch, Martin, Morton, Nicholas M., Dolga, Amalia, van Goor, Harry

Source: In Redox Biology December 2023 68

Cysteine hydropersulfide reduces lipid peroxidation and protects against myocardial ischaemia-reperfusion injury - Are endogenous persulfides mediators of ischaemic preconditioning?

Authors: Griffiths, Kayleigh, Ida, Tomoaki, Morita, Masanobu, Lamb, Reece J., Lee, Jordan J., Frenneaux, Michael P., Fukuto, Jon M., Akaike, Takaaki, Feelisch, Martin, Madhani, Melanie

Source: In Redox Biology April 2023 60

Personalized redox medicine in inflammatory bowel diseases: an emerging role for HIF-1α and NRF2 as therapeutic targets

Authors: Bourgonje, Arno R., Kloska, Damian, Grochot-Przęczek, Anna, Feelisch, Martin, Cuadrado, Antonio, van Goor, Harry

Source: In Redox Biology April 2023 60

Nitric oxide and long-term outcomes after kidney transplantation: Results of the TransplantLines cohort study

Authors: Maassen, Hanno, Said, M. Yusof, Frenay, Anne-Roos S., Koning, Anne, Post, Adrian, Riphagen, Ineke J., Heiner-Fokkema, M. Rebecca, Drabert, Kathrin, Fernandez, Bernadette O., Gans, Reinold O.B., van den Berg, Else, Navis, Gerjan, Tsikas, Dimitrios, Feelisch, Martin, Bakker, Stephan J.L., van Goor, Harry

Source: In Nitric Oxide 1 August 2022 125-126:1-11

Circulating Nitrite in Severe Asthma: Just Another Biomarker or Novel Treatment Target?

Authors: Freeman, Anna, Minnion, Magdalena, Lee, Paul H., Haitchi, Hans Michael, Kurukulaaratchy, Ramesh, Wilkinson, Tom, Feelisch, Martin

Source: Allergy; Apr2025, Vol. 80 Issue 4, p1146-1149, 4p

Subject Terms: NITRITES, BIOMARKERS, INFLAMMATION, ASTHMA, THERAPEUTICS, BRONCHIAL spasm

The effects of major abdominal surgery on skeletal muscle mitochondrial respiration in relation to systemic redox status and cardiopulmonary fitness.

Authors: Stevens, Jia L., McKenna, Helen T., Minnion, Magdalena, Murray, Andrew J., Feelisch, Martin, Martin, Daniel S.

Source: Experimental Biology & Medicine; 2025, p1-14, 14p

Divergent trajectories of cellular bioenergetics, intermediary metabolism and systemic redox status in survivors and non-survivors of critical illness

Authors: McKenna, Helen T., O'Brien, Katie A., Fernandez, Bernadette O., Minnion, Magdalena, Tod, Adam, McNally, Ben D., West, James A., Griffin, Julian L., Grocott, Michael P., Mythen, Michael G., Feelisch, Martin, Murray, Andrew J., Martin, Daniel S.

Source: In Redox Biology May 2021 41

Effects of perioperative oxygen concentration on oxidative stress in adult surgical patients: a systematic review

Authors: Oldman, Alexander H., Martin, Daniel S., Feelisch, Martin, Grocott, Michael P.W., Cumpstey, Andrew F.

Source: In British Journal of Anaesthesia March 2021 126(3):622-632

Chronic inorganic nitrate supplementation does not improve metabolic health and worsens disease progression in mice with diet-induced obesity.

Authors: Sowton, Alice P.¹, Holzner, Lorenz M. W.¹, Krause, Fynn N.², Baxter, Ruby¹, Mocciaro, Gabriele², Krzyzanska, Dominika K.¹, Minnion, Magdalena³, O'Brien, Katie A.¹, apb72@cam.ac.uk, Harrop, Matthew C.¹, Darwin, Paula M.¹, Thackray, Benjamin D.¹, Vacca, Michele^2,4, Feelisch, Martin³, Griffin, Julian L.^2,5, Murray, Andrew J.¹

Source: American Journal of Physiology: Endocrinology & Metabolism; Jan2025, Vol. 328 Issue 1, pE69-E91, 23p

Oxidative Stress and Redox-Modulating Therapeutics in Inflammatory Bowel Disease

Authors: Bourgonje, Arno R., Feelisch, Martin, Faber, Klaas Nico, Pasch, Andreas, Dijkstra, Gerard, van Goor, Harry

Source: In Trends in Molecular Medicine November 2020 26(11):1034-1046

Green tea polyphenolic antioxidants oxidize hydrogen sulfide to thiosulfate and polysulfides: A possible new mechanism underpinning their biological action

Authors: Olson, Kenneth R., Briggs, Austin, Devireddy, Monesh, Iovino, Nicholas A., Skora, Nicole C., Whelan, Jenna, Villa, Brian P., Yuan, Xiaotong, Mannam, Varun, Howard, Scott, Gao, Yan, Minnion, Magdalena, Feelisch, Martin

Source: In Redox Biology October 2020 37

Sodium thiosulfate improves renal function and oxygenation in L-NNA–induced hypertension in rats

Authors: Nguyen, Isabel T.N., Klooster, Astrid, Minnion, Magdalena, Feelisch, Martin, Verhaar, Marianne C., van Goor, Harry, Joles, Jaap A.

Source: In Kidney International August 2020 98(2):366-377

Effects of dietary nitrate supplementation on microvascular physiology at 4559 m altitude – A randomised controlled trial (Xtreme Alps)

Authors: Cumpstey, Andrew F., Hennis, Philip J., Gilbert-Kawai, Edward T., Fernandez, Bernadette O., Grant, Daniel, Jenner, William, Poudevigne, Matthieu, Moyses, Helen, Levett, Denny ZH., Cobb, Alexandra, Meale, Paula, Mitchell, Kay, Pöhnl, Helmut, Mythen, Monty G., Grocott, Michael PW., Martin, Daniel S., Feelisch, Martin

Source: In Nitric Oxide 1 January 2020 94:27-35

Inorganic nitrate and nitrite supplementation fails to improve skeletal muscle mitochondrial efficiency in mice and humans

Authors: Ntessalen, Maria, Procter, Nathan EK, Schwarz, Konstantin, Loudon, Brodie L, Minnion, Magdalena, Fernandez, Bernadette O, Vassiliou, Vassilios S, Vauzour, David, Madhani, Melanie, Constantin-Teodosiu, Dumitru, Horowitz, John D, Feelisch, Martin, Dawson, Dana, Crichton, Paul G, Frenneaux, Michael P ^*

Source: In The American Journal of Clinical Nutrition January 2020 111(1):79-89

Lower limb ischemic preconditioning combined with dietary nitrate supplementation does not influence time-trial performance in well-trained cyclists

Authors: McIlvenna, Luke C., Muggeridge, David J., Forrest (Nee Whyte), Laura J., Monaghan, Chris, Liddle, Luke, Burleigh, Mia C., Sculthorpe, Nicholas, Fernandez, Bernadette O., Feelisch, Martin, Easton, Chris

Source: In Journal of Science and Medicine in Sport July 2019 22(7):852-857

Serum free thiols in type 2 diabetes mellitus: A prospective study

Authors: Schillern, Emmelien E.M., Pasch, Andreas, Feelisch, Martin, Waanders, Femke, Hendriks, Steven H., Mencke, Rik, Harms, Geert, Groenier, Klaas H., Bilo, Henk J.G., Hillebrands, Jan-Luuk, van Goor, Harry, van Dijk, Peter R.

Source: In Journal of Clinical & Translational Endocrinology June 2019 16