Procalcitonin use in febrile children attending European emergency departments: a prospective multicenter study

Authors: Dorine M. Borensztajn, Joany M. Zachariasse, Enitan D. Carrol, Ruud G. Nijman, Ulrich von Both, Marieke Emonts, Jethro Herberg, Benno Kohlmaier, Michael Levin, Emma Lim, Ian K. Maconochie, Federico Martinón-Torres, Marko Pokorn, Irene Rivero-Calle, Aleksandra Rudzāte, Chantal D. Tan, Maria Tsolia, Clementien Vermont, Dace Zavadska, Werner Zenz, Henriette A. Moll, On behalf of PERFORM consortium: Personalised Risk assessment in febrile children to optimise Real-life Management across the European Union

Source: BMC Pediatrics, Vol 25, Iss 1, Pp 1-9 (2025)

Subject Terms: Procalcitonin, CRP, Biomarkers, Emergency Department, Pediatrics, RJ1-570

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2431

Access URL: https://doaj.org/article/efae877ecb0a478c90e7d91dd723dda1

A diagnostic host-specific transcriptome response for Mycoplasma pneumoniae pneumonia to guide pediatric patient treatment

Authors: Sandra Viz-Lasheras, Alberto Gómez-Carballa, Xabier Bello, Irene Rivero-Calle, Ana Isabel Dacosta, Myrsini Kaforou, Dominic Habgood-Coote, Aubrey J. Cunnington, Marieke Emonts, Jethro A. Herberg, Victoria J. Wright, Enitan D. Carrol, Stephane C. Paulus, Werner Zenz, Daniela S. Kohlfürst, Nina Schweintzger, Michiel Van der Flier, Ronald de Groot, Luregn J. Schlapbach, Philipp Agyeman, Andrew J. Pollard, Colin Fink, Taco T. Kuijpers, Suzanne Anderson, Ulrich Von Both, Marko Pokorn, Dace Zavadska, María Tsolia, Henriëtte A. Moll, Clementien Vermont, Michael Levin, Federico Martinón-Torres, Antonio Salas, On behalf of EUCLIDS, PERFORM, and DIAMONDS consortia

Source: Nature Communications, Vol 16, Iss 1, Pp 1-13 (2025)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/c97ca7e6166e4e949956008ec6947f56

A 5-transcript signature for discriminating viral and bacterial etiology in pediatric pneumonia

Authors: Sandra Viz-Lasheras, Alberto Gómez-Carballa, Jacobo Pardo-Seco, Xabier Bello, Irene Rivero-Calle, Ana Isabel Dacosta, Myrsini Kaforou, Dominic Habgood-Coote, Aubrey J. Cunnington, Marieke Emonts, Jethro A. Herberg, Victoria J. Wright, Enitan D. Carrol, Stephane C. Paulus, Werner Zenz, Daniela S. Kohlfürst, Michiel Van der Flier, Ronald de Groot, Luregn J. Schlapbach, Philipp Agyeman, Andrew J. Pollard, Colin Fink, Taco T. Kuijpers, Suzanne Anderson, Cristina Calvo, María del Carmen Martínez-Padilla, Ana Pérez-Aragón, Esteban Gómez-Sánchez, Juan Valencia-Ramos, Francisco Giménez-Sánchez, Paula Alonso-Quintela, Laura Moreno-Galarraga, Ulrich von Both, Marko Pokorn, Dace Zavadska, María Tsolia, Clementien L. Vermont, Henriëtte A. Moll, Michael Levin, Federico Martinón-Torres, Antonio Salas

Source: iScience, Vol 28, Iss 2, Pp 111747- (2025)

Subject Terms: Pediatrics, Diagnostics, Body substance sample, Clinical microbiology, Transcriptomics, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004225000069; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/34e8bfdac40344a181935441b7b82c4e

Integration and validation of host transcript signatures, including a novel 3-transcript tuberculosis signature, to enable one-step multiclass diagnosis of childhood febrile disease

Authors: Samuel Channon-Wells, Dominic Habgood-Coote, Ortensia Vito, Rachel Galassini, Victoria J. Wright, Andrew J. Brent, Robert S. Heyderman, Suzanne T. Anderson, Brian Eley, Federico Martinón-Torres, Michael Levin, Myrsini Kaforou, On behalf of UK Kawasaki Disease Genetics, ILULU, GENDRES and EUCLIDS consortia, Jethro A. Herberg

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)

Subject Terms: Gene expression, Diagnostics, Kawasaki disease, Tuberculosis, Bacterial infection, Viral infection, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/aa9f5af63b3447538a074a42a9b96c2b

Disparate kinetics in immune response of two different Haemophilus influenzae type b conjugate vaccines: Immunogenicity and safety observations from a randomized controlled phase IV study in healthy infants and toddlers using a 2+1 schedule

Authors: Federico Martinón-Torres, Ignacio Salamanca de la Cueva, Michael Horn, Soeren Westerholt, Samantha Bosis, Nadia Meyer, Brigitte Cheuvart, Navpreet Virk, Rupert W. Jakes, Maurine Duchenne, Peter Van den Steen

Source: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

Subject Terms: 2+1 schedule, antibody avidity, Haemophilus influenzae type b, hexavalent vaccine, immunogenicity, immune response kinetics, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/5ba570dd9f674f9d9fdac66f61eb98d2

Assessment of effectiveness and impact of universal prophylaxis with nirsevimab for prevention of hospitalizations due to respiratory syncytial virus in infants. The NIRSE-GAL study protocol

Authors: Narmeen Mallah, Sonia Ares-Gómez, Jacobo Pardo-Seco, Alberto Malvar-Pintos, María-Isolina Santiago-Pérez, Olaia Pérez-Martínez, María-Teresa Otero-Barrós, Nuria Suárez-Gaiche, Rolf Kramer, Jing Jin, Leticia Platero-Alonso, Rosa-María Alvárez-Gil, Olga-María Ces-Ozores, Victoria Nartallo-Penas, Susana Mirás-Carballal, Marta Piñeiro-Sotelo, Juan-Manuel González-Pérez, Carmen Rodríguez-Tenreiro, Irene Rivero-Calle, Antonio Salas, Carmen Durán-Parrondo, Federico Martinón-Torres

Source: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

Subject Terms: Effectiveness, immunization, longitudinal population-based study, lower respiratory tract infection, nirsevimab, respiratory syncytial virus, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/61987a233504468ca65b4ba00881ee59

COVID-19 InfoVaccines: A WHO-supported educational project to promote COVID-19 vaccination information among professionals and the general population

Authors: Narmeen Mallah, Jacobo Pardo-Seco, Irene Rivero-Calle, Ouhao Zhu-Huang, María Fernández Prada, Catharina Reynen-de Kat, Oleg Benes, Liudmila Mosina, Siddhartha Sankar-Datta, Olga Aleksinskaya, David Díaz, Vusala Allahverdiyeva, Yevgenii Grechukha, Tamara Jobava, Mariia Savchyna, Pavla Kortusova, Ioana Novac, Federico Martinón-Torres

Source: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

Subject Terms: COVID-19, COVID-19 InfoVaccines, educational tool, Europe, misinformation, World Health Organization, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/9f69d43e3ef945de90db22c95351b089

4CMenB journey to the 10-year anniversary and beyond

Authors: Véronique Abitbol, Federico Martinón-Torres, Muhamed-Kheir Taha, Terry Nolan, Alessandro Muzzi, Stefania Bambini, Ray Borrow, Daniela Toneatto, Laura Serino, Rino Rappuoli, Mariagrazia Pizza

Source: Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)

Subject Terms: 4CMenB, Bexsero, cross-protection, effectiveness, impact, Neisseria meningitidis, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2164-5515; https://doaj.org/toc/2164-554X

Access URL: https://doaj.org/article/380746a45f9448248f21e680320ecf7a

Whole exome sequencing identifies new susceptibility candidates underlying community-acquired pneumonia

Authors: Jacobo Pardo-Seco, Sandra Viz-Lasheras, Xabier Bello, Alberto Gómez-Carballa, Alba Camino-Mera, Sara Pischedda, María José Currás-Tuala, Irene Rivero-Calle, Ana Dacosta-Urbieta, Fernando Caamaño-Viña, Carmen Rodríguez-Tenreiro Sánchez, Isabel Cifuentes, Cristina Méndez, Chiea Chuen Khor, Federico Martinón-Torres, Antonio Salas

Source: Genes and Diseases, Vol 11, Iss 6, Pp 101170- (2024)

Subject Terms: Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304223004531; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/3297eb1d370a4aeda009210f45cd3b32

The genomic evolutionary dynamics and global circulation patterns of respiratory syncytial virus

Authors: Annefleur C. Langedijk, Bram Vrancken, Robert Jan Lebbink, Deidre Wilkins, Elizabeth J. Kelly, Eugenio Baraldi, Abiel Homero Mascareñas de Los Santos, Daria M. Danilenko, Eun Hwa Choi, María Angélica Palomino, Hsin Chi, Christian Keller, Robert Cohen, Jesse Papenburg, Jeffrey Pernica, Anne Greenough, Peter Richmond, Federico Martinón-Torres, Terho Heikkinen, Renato T. Stein, Mitsuaki Hosoya, Marta C. Nunes, Charl Verwey, Anouk Evers, Leyla Kragten-Tabatabaie, Marc A. Suchard, Sergei L. Kosakovsky Pond, Chiara Poletto, Vittoria Colizza, Philippe Lemey, Louis J. Bont, on behalf of the INFORM-RSV Study Group

Source: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/45e7038869c54007951a43a1f120bf0b

Use of expanded Neisseria meningitidis serogroup B panels with the serum bactericidal antibody assay for the evaluation of meningococcal B vaccine effectiveness

Authors: Ray Borrow, Federico Martinón-Torres, Véronique Abitbol, Anar Andani, Scott Preiss, Alessandro Muzzi, Laura Serino, Woo-Yun Sohn

Source: Expert Review of Vaccines, Vol 22, Iss 1, Pp 738-748 (2023)

Subject Terms: 4cmenb, complement, invasive meningococcal disease, menb-fhbp, neisseria meningitidis, serum bactericidal antibody assay, vaccine, vaccine effectiveness, Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://doaj.org/toc/1476-0584; https://doaj.org/toc/1744-8395

Access URL: https://doaj.org/article/4e1c2a33874d4f68b50c1a9a666b28e7

Music compensates for altered gene expression in age-related cognitive disorders

Authors: Alberto Gómez-Carballa, Laura Navarro, Jacobo Pardo-Seco, Xabier Bello, Sara Pischedda, Sandra Viz-Lasheras, Alba Camino-Mera, María José Currás, Isabel Ferreirós, Narmeen Mallah, Sara Rey-Vázquez, Lorenzo Redondo, Ana Dacosta-Urbieta, Fernando Caamaño-Viña, Irene Rivero-Calle, Carmen Rodriguez-Tenreiro, Federico Martinón-Torres, Antonio Salas

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/935e4ad64598475badf890d9f9fbbfde

Meningococcal Disease in the Post–COVID-19 Era: A Time to Prepare

Authors: David E. Bloom, Paolo Bonanni, Federico Martinón-Torres, Peter C. Richmond, Marco A. P. Safadi, David M. Salisbury, Apostolos Charos, Katharina Schley, Jamie Findlow, Paul Balmer

Source: Infectious Diseases and Therapy, Vol 12, Iss 12, Pp 2649-2663 (2023)

Subject Terms: COVID-19, Epidemiology, Immunization programs, Incidence, Vaccines, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/2193-8229; https://doaj.org/toc/2193-6382

Access URL: https://doaj.org/article/c523a0068eb04bd1a5c9763bb74ef4ba

Multi-tissue transcriptomics of a unique monozygotic discordant twin case of severe progressive osseous heteroplasia

Authors: Alberto Gómez-Carballa, María José Currás-Tuala, Sara Pischedda, Miriam Cebey-López, José Gómez-Rial, Irene Rivero-Calle, Jacobo Pardo-Seco, Xabier Bello, Sandra Viz-Lasheras, Antonio Justicia-Grande, Julián Montoto-Louzao, Alba Camino-Mera, Isabel Ferreirós-Vidal, Máximo Fraga, José R. Antúnez, Rodolfo Gómez, Federico Martinón-Torres, Antonio Salas

Source: Genes and Diseases, Vol 11, Iss 3, Pp 100981- (2024)

Subject Terms: Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S235230422300226X; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/3273af70b4774d708bfe524a19f613d7

Do we really want to end meningococcal disease (and current inequity)?

Authors: Federico Martinón-Torres

Source: Anales de Pediatría (English Edition), Vol 100, Iss 5, Pp e28-e30 (2024)

Subject Terms: Pediatrics, RJ1-570

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2341287924000784; https://doaj.org/toc/2341-2879

Access URL: https://doaj.org/article/bd59ef7f1c2146039f2df078d0138602

Addressing influenza’s underestimated burden – Iberian experts call to action

Authors: Ángel Gil-de-Miguel, Javier Díez-Domingo, Federico Martinón-Torres, Esther Redondo Margüello, Raúl Ortiz de Lejarazu Leonardo, Tomàs Pumarola, Jaime Correia de Sousa, Carlos Rabaçal, João Raposo, Carlos Robalo Cordeiro, Filipe Froes

Source: BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-5 (2023)

Subject Terms: Influenza, Burden, Epidemiology, Spain, Portugal, Hospitalization, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/5d92e2f6d6a648baac5b8d8f2674dbef

Single‐cell immune profiling reveals markers of emergency myelopoiesis that distinguish severe from mild respiratory syncytial virus disease in infants

Authors: Nevena Zivanovic, Deniz Öner, Yann Abraham, Joseph McGinley, Simon B. Drysdale, Joanne G. Wildenbeest, Marjolein Crabbe, Greet Vanhoof, Kim Thys, Ryan S. Thwaites, Hannah Robinson, Louis Bont, Peter J. M. Openshaw, Federico Martinón‐Torres, RESCEU Investigators, Andrew J. Pollard, Jeroen Aerssens

Source: Clinical and Translational Medicine, Vol 13, Iss 12, Pp n/a-n/a (2023)

Subject Terms: Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/ac35e4f76db64145b22518aa1ef50b98

Rule of Prevention: a potential framework to evaluate preventive interventions for rare diseases

Authors: Eddie Gibson, Daniel A. Ollendorf, Steven Simoens, David E Bloom, Federico Martinón-Torres, David Salisbury, Johan Louis Severens, Mondher Toumi, Daniel Molnar, Kinga Meszaros, Woo-Yun Sohn, Najida Begum

Source: Journal of Market Access & Health Policy, Vol 11, Iss 1 (2023)

Subject Terms: Prevention, vaccination, assessment, value, rare disease, Public aspects of medicine, RA1-1270, Business, HF5001-6182

File Description: electronic resource

Relation: https://doaj.org/toc/2001-6689

Access URL: https://doaj.org/article/4432939b134d41eb9d2da682a1d51f85

Intravenous immunoglobulin treatment in childhood encephalitis (IgNiTE): a randomised controlled trial

Authors: Simon Nadel, Claire Cameron, David Pace, Rachel Kneen, Matilda Hill, Federico Martinón-Torres, Tom Solomon, Mandy Wan, Angela Vincent, Michael Absoud, Patrick Waters, Manish Sadarangani, Xinxue Liu, Andrew J Pollard, Sanjay Bhate, Ly-Mee Yu, John Alexander, Sarosh Irani, David Kerr, Andrew Collinson, Ava Easton, William Whitehouse, Ming Lim, Emma Plested, Paul Heath, Dominic Smith, Michael Pike, Adilia Warris, Anna Riddell, Paddy McMaster, Simon Kerridge, Louise Willis, Christopher Clark, Victoria Gray, Jay Shetty, John Livingston, Kling Chong, Vishal Mehta, Charles Warlow, Jo Haviland, Alice Jollands, Shakeel Herwitker, Daniel O’Connor, Yama Mujadidi, Lauren Burke, Mildred Iro, Sagida Bibi, Liberty Cantrell, Mike Pike, Chris A. Clark, Sophie Bradshaw, Svetlana Milca, Mike Bale, Sonia Bale, Alan Percival, Meryn Voysey, Amy Beveridge, Amber Thompson, Parvinder Alley, Archana Desurkar, Elma Stephen, Steve Welch, Kayal Vijayakumar, Leena Mewasingh, Christian de Goede

Source: BMJ Open, Vol 13, Iss 11 (2023)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/13/11/e072134.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/d95df2e0dc6244059c752071a77d38ed

Clinical and economic burden of physician-diagnosed influenza in adults during the 2017/2018 epidemic season in Spain

Authors: Ángel Gil-de-Miguel, Federico Martinón-Torres, Javier Díez-Domingo, Raúl Ortiz de Lejarazu Leonardo, Tomàs Pumarola, Mafalda Carmo, Georgina Drago, Juan Luis López-Belmonte, Hélène Bricout, Caroline de Courville, Esther Redondo Margüello

Source: BMC Public Health, Vol 22, Iss 1, Pp 1-12 (2022)

Subject Terms: Influenza, Burden, Epidemiology, Spain, Health resources, Hospitalization, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2458

Access URL: https://doaj.org/article/4f898017c8c34f4299e759a458d8a5fd