Adipokines as potential pharmacological targets for immune inflammatory rheumatic diseases: Focus on rheumatoid arthritis, osteoarthritis, and intervertebral disc degeneration

Authors: Farrag, Yousof, Farrag, Mariam, Varela-García, María, Torrijos-Pulpón, Carlos, Capuozzo, Maurizio, Ottaiano, Alessando, Lago, Francisca, Mera, Antonio, Pino, Jesus, Gualillo, Oreste

Source: In Pharmacological Research July 2024 205

Metabolomic signature and molecular profile of normal and degenerated human intervertebral disc cells

Authors: Francisco, Vera, Ait Eldjoudi, Djedjiga, González-Rodríguez, María, Ruiz-Fernández, Clara, Cordero-Barreal, Alfonso, Marques, Patrice, Sanz, Maria Jesus, Real, José T., Lago, Francisca, Pino, Jesus, Farrag, Yousof, Gualillo, Oreste

Source: In The Spine Journal October 2023 23(10):1549-1562

Injectable hybrid hydrogels physically crosslinked based on carrageenan and green graphene for tissue repair

Authors: Moncada, Danny, Rico, Maite, Montero, Belén, Rodríguez-Llamazares, Saddys, Feijoo-Bandín, Sandra, Gualillo, Oreste, Lago, Francisca, Aragón-Herrera, Alana, Salavagione, Horacio, Pettinelli, Natalia, Bouza, Rebeca, Farrag, Yousof

Source: In International Journal of Biological Macromolecules 30 April 2023 235

Adipokines as targets in musculoskeletal immune and inflammatory diseases

Authors: González-Rodríguez, María, Ruiz-Fernández, Clara, Cordero-Barreal, Alfonso, Ait Eldjoudi, Djedjiga, Pino, Jesus, Farrag, Yousof, Gualillo, Oreste

Source: In Drug Discovery Today November 2022 27(11)

WISP-2 modulates the induction of inflammatory mediators and cartilage catabolism in chondrocytes

Authors: Ruiz-Fernández, Clara, González-Rodríguez, María, Abella, Vanessa, Francisco, Vera, Cordero-Barreal, Alfonso, Ait Eldjoudi, Djedjiga, Farrag, Yousof, Pino, Jesús, Conde-Aranda, Javier, González-Gay, Miguel Ángel, Mera, Antonio, Mobasheri, Ali, García-Caballero, Lucía, Gándara-Cortés, Marina, Lago, Francisca, Scotece, Morena, Gualillo, Oreste

Source: In Laboratory Investigation September 2022 102(9):989-999

E74‐like ETS transcription factor 3 expression and regulation in human intervertebral disc.

Authors: González‐Rodríguez, María, Ait Eldjoudi, Djedjiga, Cordero‐Barreal, Alfonso, Farrag, Mariam, Varela‐García, María, Ruiz‐Fernández, Clara, Torrijos‐Pulpón, Carlos, Lago, Francisca, García‐Caballero, Lucía, Farrag, Yousof, Conde‐Aranda, Javier, Pino, Jesus, Gualillo, Oreste

Source: JOR Spine; Mar2025, Vol. 8 Issue 1, p1-15, 15p

Subject Terms: TRANSCRIPTION factors, INTERVERTEBRAL disk, GENE expression, NUCLEUS pulposus, CHRONIC pain

Poly(ethylene Glycol) Methyl Ether Methacrylate-Based Injectable Hydrogels: Swelling, Rheological, and In Vitro Biocompatibility Properties with ATDC5 Chondrogenic Lineage.

Authors: Farrag, Yousof¹ (AUTHOR) djidji.aiteldjoudi@gmail.com, Ait Eldjoudi, Djedjiga¹ (AUTHOR) mariam.r.farrag@gmail.com, Farrag, Mariam¹ (AUTHOR) maria.gonzalez3112@gmail.com, González-Rodríguez, María¹ (AUTHOR) clararf94@gmail.com, Ruiz-Fernández, Clara¹ (AUTHOR) sitoalcorba@gmail.com, Cordero, Alfonso¹ (AUTHOR) merymodre@gmail.com, Varela-García, María¹ (AUTHOR) carlostorrijos00@gmail.com, Torrijos Pulpón, Carlos¹ (AUTHOR) oreste.gualillo@sergas.es, Bouza, Rebeca² (AUTHOR) rebeca.bouza@udc.es, Lago, Francisca³ (AUTHOR) francisca.lago.paz@sergas.es, Pino, Jesus¹ (AUTHOR) yousof.farrag@gmail.com, Alvarez-Lorenzo, Carmen⁴ (AUTHOR) carmen.alvarez.lorenzo@usc.es, Gualillo, Oreste¹ (AUTHOR)

Source: Polymers (20734360). Dec2023, Vol. 15 Issue 24, p4635. 16p.

Subject Terms: *HYDROGELS, *ETHYLENE glycol, *METHACRYLATES, *METHYL ether, *NUCLEAR magnetic resonance spectroscopy, *METHYL methacrylate, *NITRIC-oxide synthases

Poly(hydroxybutyrate-co-hydroxyvalerate) microparticles embedded in κ-carrageenan/locust bean gum hydrogel as a dual drug delivery carrier

Authors: Pettinelli, Natalia, Rodríguez-Llamazares, Saddys, Farrag, Yousof, Bouza, Rebeca, Barral, Luis, Feijoo-Bandín, Sandra, Lago, Francisca

Source: In International Journal of Biological Macromolecules 1 March 2020 146:110-118

Entrapment of chitosan, pectin or κ-carrageenan within methacrylate based hydrogels: Effect on swelling and mechanical properties

Authors: Pettinelli, Natalia, Rodríguez-Llamazares, Saddys, Abella, Vanessa, Barral, Luis, Bouza, Rebeca, Farrag, Yousof, Lago, Francisca

Source: In Materials Science & Engineering C March 2019 96:583-590

A retrospective study describing the acetabular consequences of Legg- Calve-Perthes disease.

Authors: Varela-García, María, Torrijos-Pulpón, Carlos, Pino-López, Laura, Farrag, Yousof, Forneiro-Pérez, Rocío, Conde-Aranda, Javier, Gualillo, Oreste, Pino, Jesus

Source: BMC Musculoskeletal Disorders; 9/20/2024, Vol. 25 Issue 1, p1-8, 8p

Subject Terms: FEMORAL epiphysis, FEMUR head, PROGNOSIS, STATISTICAL significance, SAMPLE size (Statistics), CONGENITAL hip dislocation

Injectable Carrageenan/Green Graphene Oxide Hydrogel: A Comprehensive Analysis of Mechanical, Rheological, and Biocompatibility Properties.

Authors: Moncada, Danny, Bouza, Rebeca, Rico, Maite, Rodríguez-Llamazares, Saddys, Pettinelli, Natalia, Aragón-Herrera, Alana, Feijóo-Bandín, Sandra, Gualillo, Oreste, Lago, Francisca, Farrag, Yousof, Salavagione, Horacio

Source: Polymers (20734360); Aug2024, Vol. 16 Issue 16, p2345, 14p

Subject Terms: LOCUST bean gum, RHEOLOGY, GRAPHENE oxide, BIOPOLYMERS, CELL proliferation, CARRAGEENANS

Starch edible films loaded with donut-shaped starch microparticles

Authors: Farrag, Yousof, Malmir, Sara, Montero, Belén, Rico, Maite, Rodríguez-Llamazares, Saddys, Barral, Luis, Bouza, Rebeca

Source: In LWT December 2018 98:62-68

Starch films loaded with donut-shaped starch-quercetin microparticles: Characterization and release kinetics

Authors: Farrag, Yousof, Ide, Walther, Montero, Belén, Rico, Maite, Rodríguez-Llamazares, Saddys, Barral, Luis, Bouza, Rebeca

Source: In International Journal of Biological Macromolecules 15 October 2018 118 Part B:2201-2207

Preparation of starch nanoparticles loaded with quercetin using nanoprecipitation technique

Authors: Farrag, Yousof, Ide, Walther, Montero, Belén, Rico, Maite, Rodríguez-Llamazares, Saddys, Barral, Luis, Bouza, Rebeca

Source: In International Journal of Biological Macromolecules 15 July 2018 114:426-433

Effect of Different Plasticizers on Thermal, Crystalline, and Permeability Properties of Poly(3–hydroxybutyrate–co−3–hydroxyhexanoate) Films.

Authors: Farrag, Yousof¹ (AUTHOR), Barral, Luis² (AUTHOR), Gualillo, Oreste¹ (AUTHOR), Moncada, Danny² (AUTHOR), Montero, Belén² (AUTHOR), Rico, Maite² (AUTHOR), Bouza, Rebeca² (AUTHOR) rebeca.bouza@udc.es

Source: Polymers (20734360). Sep2022, Vol. 14 Issue 17, p3503. 14p.

Subject Terms: *PLASTICIZERS, *PERMEABILITY, *MOLECULAR weights, *GLASS transition temperature, *DIFFERENTIAL scanning calorimetry, *WATER vapor, *ETHYLENE glycol

473 - E74-LIKE ETS TRANSCRIPTION FACTOR 3 (ELF3): A NOVEL PRO-INFLAMMATORY MEDIATOR IN INTERVERTEBRAL DISC DEGENERATION.

Authors: Farrag, Mariam, González-Rodríguez, María, Eldjoudi, Djedjiga Ait, Cordero-Barreal, Alfonso, Varela-García, María, Pulpón, Carlos Torrijos, Conde-Aranda, Javier, Pino, Jesus, Farrag, Yousof, Gualillo, Oreste

Source: Osteoarthritis & Cartilage; 2025 Supplement, Vol. 33, pS338-S339, 2p

Oleocanthal, an Antioxidant Phenolic Compound in Extra Virgin Olive Oil (EVOO): A Comprehensive Systematic Review of Its Potential in Inflammation and Cancer.

Authors: González-Rodríguez, María, Ait Edjoudi, Djedjiga, Cordero-Barreal, Alfonso, Farrag, Mariam, Varela-García, María, Torrijos-Pulpón, Carlos, Ruiz-Fernández, Clara, Capuozzo, Maurizio, Ottaiano, Alessandro, Lago, Francisca, Pino, Jesús, Farrag, Yousof, Gualillo, Oreste

Source: Antioxidants; Dec2023, Vol. 12 Issue 12, p2112, 16p

Subject Terms: OLIVE oil, PHENOLS, MEDITERRANEAN diet, RHEUMATISM, INFLAMMATION

Novel Self‐Reinforced Films Based on Poly (3‐Hydroxybutyrate‐Co‐3‐Hydroxyvalerate) (PHBV) and PHBV Microparticles.

Authors: Malmir, Sara¹, Montero, Belén¹, Rico, Maite¹, Barral, Luis¹, Bouza, Rebeca¹, rebeca.bouza@udmc.es, Farrag, Yousof¹

Source: Polymer Engineering & Science; Jan2019 Supplement S1, Vol. 59, pE120-E128, 9p

Asprosin in health and disease, a new glucose sensor with central and peripheral metabolic effects.

Authors: Farrag, Mariam, Eldjoudi, Djedjiga Ait, González-Rodríguez, María, Cordero-Barreal, Alfonso, Ruiz-Fernández, Clara, Capuozzo, Maurizio, González-Gay, Miguel Angel, Mera, Antonio, Lago, Francisca, Soffar, Ahmed, Essawy, Amina, Pino, Jesus, Farrag, Yousof, Gualillo, Oreste

Source: Frontiers in Endocrinology; 1/5/2023, Vol. 13, p1-17, 17p

Subject Terms: METABOLIC disorders, FATTY liver, WHITE adipose tissue, TYPE 2 diabetes, CARDIOVASCULAR diseases, MEDICAL research, GLUCOSE

Progranulin in Musculoskeletal Inflammatory and Degenerative Disorders, Focus on Rheumatoid Arthritis, Lupus and Intervertebral Disc Disease: A Systematic Review.

Authors: González-Rodríguez, María, Ait Edjoudi, Djedjiga, Cordero Barreal, Alfonso, Ruiz-Fernández, Clara, Farrag, Mariam, González-Rodríguez, Beatriz, Lago, Francisca, Capuozzo, Maurizio, Gonzalez-Gay, Miguel Angel, Mera Varela, Antonio, Pino, Jesús, Farrag, Yousof, Gualillo, Oreste

Source: Pharmaceuticals (14248247); Dec2022, Vol. 15 Issue 12, p1544, 12p

Subject Terms: RHEUMATOID arthritis, PROGRANULIN, DEGENERATION (Pathology), SYSTEMIC lupus erythematosus, SYNOVIAL fluid, INTERVERTEBRAL disk, RISK perception