Genetically elevated high‐density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease

Authors: Peloso, Gina M., Lee, Sven J., Sims, R., Lee, S.J., Naj, A.C., Bellenguez, C., Badarinarayan, N., Jakobsdottir, J., Kunkle, B.W., Boland, A., Raybould, R., Bis, J.C., Martin, E.R., Grenier‐Boley, B., Heilmann‐Heimbach, S., Chouraki, V., Kuzma, A.B., Sleegers, K., Vronskaya, M., Ruiz, A., Graham, R.R., Olaso, R., Hoffmann, P., Grove, M.L., Vardarajan, B.N., Hiltunen, M., Nöthen, M.M., White, C.C., Hamilton‐Nelson, K.L., Epelbaum, J., Maier, W., Choi, S.H., Beecham, G.W., Dulary, C., Herms, S., Smith, A.V., Funk, C.C., Forstner, A.J., Ahmad, S., Li, H., Bacq, D., Harold, D., Satizabal, C.L., Valladares, O., Squassina, A., Thomas, R., Brody, J.A., Qu, L., Sánchez‐Juan, P., Morgan, T., Wolters, F.J., Zhao, Y., Garcia, F.S., Denning, N., Fornage, M., Malamon, J., Naranjo, M.C.D., Majounie, E., Mosley, T.H., Dombroski, B., Wallon, D., Lupton, M.K., Dupuis, J., Whitehead, P., Fratiglioni, L., Medway, C., Jian, X., Mukherjee, S., Keller, L., Brown, K., Lin, H., Cantwell, L.B., Panza, F., McGuinness, B., Moreno‐Grau, S., Burgess, J.D., Solfrizzi, V., Proitsi, P., Adams, H.H., Allen, M., Seripa, D., Pastor, P., Cupples, L.A., Price, N.D., Hannequin, D., Frank‐García, A., Levy, D., Chakrabarty, P., Caffarra, P., Giegling, I., Beiser, A.S., Giedraitis, V., Hampel, H., Garcia, M.E., Wang, X., Lannfelt, L., Mecocci, P., Eiriksdottir, G., Crane, P.K., Pasquier, F., Boccardi, V., Henández, I., Barber, R.C., Scherer, M., Tarraga, L., Adams, P.M., Leber, M., Chen, Y., Albert, M.S., Riedel‐Heller, S., Emilsson, V., Beekly, D., Braae, A., Schmidt, R., Blacker, D., Masullo, C., Schmidt, H., Doody, R.S., Spalletta, G., Longstreth, W.T., Fairchild, T.J., Bossù, P., Lopez, O.L., Frosch, M.P., Sacchinelli, E., Ghetti, B., Yang, Q., Huebinger, R.M., Jessen, F., Li, S., Kamboh, M.I., Morris, J., Sotolongo‐Grau, O., Katz, M.J., Corcoran, C., Dunstan, M., Braddel, A., Thomas, C., Meggy, A., Marshall, R., Gerrish, A., Chapman, J., Aguilar, M., Taylor, S., Hill, M., Fairén, M.D., Hodges, A., Vellas, B., Soininen, H., Kloszewska, I., Daniilidou, M., Uphill, J., Patel, Y., Hughes, J.T., Lord, J., Turton, J., Hartmann, A.M., Cecchetti, R., Fenoglio, C., Serpente, M., Arcaro, M., Caltagirone, C., Orfei, M.D., Ciaramella, A., Pichler, S., Mayhaus, M., Gu, W., Lleó, A., Fortea, J., Blesa, R., Barber, I.S., Brookes, K., Cupidi, C., Maletta, R.G., Carrell, D., Sorbi, S., Moebus, S., Urbano, M., Pilotto, A., Kornhuber, J., Bosco, P., Todd, S., Craig, D., Johnston, J., Gill, M., Lawlor, B., Lynch, A., Fox, N.C., Hardy, J., Albin, R.L., Apostolova, L.G., Arnold, S.E., Asthana, S., Atwood, C.S., Baldwin, C.T., Barnes, L.L., Barral, S., Beach, T.G., Becker, J.T., Bigio, E.H., Bird, T.D., Boeve, B.F., Bowen, J.D., Boxer, A., Burke, J.R., Burns, J.M., Buxbaum, J.D., Cairns, N.J., Cao, C., Carlson, C.S., Carlsson, C.M., Carney, R.M., Carrasquillo, M.M., Carroll, S.L., Diaz, C.C., Chui, H.C., Clark, D.G., Cribbs, D.H., Crocco, E.A., DeCarli, C., Dick, M., Duara, R., Evans, D.A., Faber, K.M., Fallon, K.B., Fardo, D.W., Farlow, M.R., Ferris, S., Foroud, T.M., Galasko, D.R., Gearing, M., Geschwind, D.H., Gilbert, J.R., Graff‐Radford, N.R., Green, R.C., Growdon, J.H., Hamilton, R.L., Harrell, L.E., Honig, L.S., Huentelman, M.J., Hulette, C.M., Hyman, B.T., Jarvik, G.P., Abner, E., Jin, L.W., Jun, G., Karydas, A., Kaye, J.A., Kim, R., Kowall, N.W., Kramer, J.H., LaFerla, F.M., Lah, J.J., Leverenz, J.B., Levey, A.I., Li, G., Lieberman, A.P., Lunetta, K.L., Lyketsos, C.G., Marson, D.C., Martiniuk, F., Mash, D.C., Masliah, E., McCormick, W.C., McCurry, S.M., McDavid, A.N., McKee, A.C., Mesulam, M., Miller, B.L., Miller, C.A., Miller, J.W., Morris, J.C., Murrell, J.R., Myers, A.J., O'Bryant, S., Olichney, J.M., Pankratz, V.S., Parisi, J.E., Paulson, H.L., Perry, W., Peskind, E., Pierce, A., Poon, W.W., Potter, H., Quinn, J.F., Raj, A., Raskind, M., Reisberg, B., Reitz, C., Ringman, J.M., Roberson, E.D., Rogaeva, E., Rosen, H.J., Rosenberg, R.N., Sager, M.A., Saykin, A.J., Schneider, J.A., Schneider, L.S., Seeley, W.W., Smith, A.G., Sonnen, J.A., Spina, S., Stern, R.A., Swerdlow, R.H., Tanzi, R.E., Thornton‐Wells, T.A., Trojanowski, J.Q., Troncoso, J.C., Van Deerlin, V.M., Van Eldik, L.J., Vinters, H.V., Vonsattel, J.P., Weintraub, S., Welsh‐Bohmer, K.A., Wilhelmsen, K.C., Williamson, J., Wingo, T.S., Woltjer, R.L., Wright, C.B., Yu, C.E., Yu, L., Garzia, F., Golamaully, F., Septier, G., Engelborghs, S., Vandenberghe, R., De Deyn, P.P., Fernadez, C.M., Benito, Y.A., Thonberg, H., Forsell, C., Lilius, L., Kinhult‐Stählbom, A., Kilander, L., Brundin, R., Concari, L., Helisalmi, S., Koivisto, A.M., Haapasalo, A., Dermecourt, V., Fievet, N., Hanon, O., Dufouil, C., Brice, A., Ritchie, K., Dubois, B., Himali, J.J., Keene, C.D., Tschanz, J., Fitzpatrick, A.L., Kukull, W.A., Norton, M., Aspelund, T., Larson, E.B., Munger, R., Rotter, J.I., Lipton, R.B., Bullido, M.J., Hofman, A., Montine, T.J., Coto, E., Boerwinkle, E., Petersen, R.C., Alvarez, V., Rivadeneira, F., Reiman, E.M., Gallo, M., O'Donnell, C.J., Reisch, J.S., Bruni, A.C., Royall, D.R., Dichgans, M., Sano, M., Galimberti, D., St George‐Hyslop, P., Scarpini, E., Tsuang, D.W., Mancuso, M., Bonuccelli, U., Winslow, A.R., Daniele, A., Wu, C.K., Peters, O., Nacmias, B., Riemenschneider, M., Heun, R., Brayne, C., Rubinsztein, D.C., Bras, J., Guerreiro, R., Al‐Chalabi, A., Shaw, C.E., Collinge, J., Mann, D., Tsolaki, M., Clarimón, J., Sussams, R., Lovestone, S., O'Donovan, M.C., Owen, M.J., Behrens, T.W., Mead, S., Goate, A.M., Uitterlinden, A.G., Holmes, C., Cruchaga, C., Ingelsson, M., Bennett, D.A., Powell, J., Golde, T.E., Graff, C., De Jager, P.L., Morgan, K., Ertekin‐Taner, N., Combarros, O., Psaty, B.M., Passmore, P., Younkin, S.G., Berr, C., Gudnason, V., Rujescu, D., Dickson, D.W., Dartigues, J.F., DeStefano, A.L., Ortega‐Cubero, S., Hakonarson, H., Campion, D., Boada, M., Kauwe, J.K., Farrer, L.A., Van Broeckhoven, C., Ikram, M.A., Jones, L., Haines, J.L., Tzourio, C., Launer, L.J., Escott‐Price, V., Mayeux, R., Deleuze, J.F., Amin, N., Holmans, P.A., Pericak‐Vance, M.A., Amouyel, P., Duijn, C.M., Ramirez, A., Wang, L.S., Lambert, J.C., Seshadri, S., Williams, J., Schellenberg, G.D., Destefano, Anita L., Seshardi, Sudha

Source: Alzheimer's & dementia.Diagnosis, assessment & disease monitoring. 10(C):595-598

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099904258.0x000001&indx=1&recIds=ETOCvdc_100099904258.0x000001

Treatment of Mild Cognitive Impairment (MCI)
Perspective on mild cognitive impairment (MCI)

Authors: Farlow, M.R.

Source: CURRENT ALZHEIMER RESEARCH. 6(4):362-367

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN073060200&indx=1&recIds=ETOCCN073060200

The role of choroid plexus in IVIG-induced beta-amyloid clearance

Authors: Gu, H., Zhong, Z., Jiang, W., Du, E., Dodel, R., Liu, J., Farlow, M.R., Zheng, W., Du, Y.

Source: In Neuroscience 13 June 2014 270:168-176

Evaluating High-Dose Rivastigmine Patch in Severe Alzheimer's Disease: Analyses with Concomitant Memantine Usage as a Factor

Authors: Grossberg, G.T., Farlow, M.R., Meng, X., Velting, D.M.

Source: CURRENT ALZHEIMER RESEARCH. 12(1):53-60

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN364709376&indx=1&recIds=ETOCRN364709376

Caffeic acid phenethyl ester extends survival of a mouse model of amyotrophic lateral sclerosis

Authors: Fontanilla, C.V., Wei, X., Zhao, L., Johnstone, B., Pascuzzi, R.M., Farlow, M.R., Du, Y.

Source: In Neuroscience 15 March 2012 205:185-193

Caffeic acid phenethyl ester prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurodegeneration

Authors: Fontanilla, C.V., Ma, Z., Wei, X., Klotsche, J., Zhao, L., Wisniowski, P., Dodel, R.C., Farlow, M.R., Oertel, W.H., Du, Y.

Source: In Neuroscience 2011 188:135-141

Immunotherapy for Alzheimer's Disease
Advances in Neurologic Therapy

Authors: Farlow, M.R., Brosch, J.R.

Source: NEUROLOGIC CLINICS. 31(3):869-878

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN339160787&indx=1&recIds=ETOCRN339160787

Altered Default Mode Network Connectivity in Older Adults with Cognitive Complaints and Amnestic Mild Cognitive Impairment

Authors: Wang, Y., Risacher, S.L., West, J.D., McDonald, B.C., MaGee, T.R., Farlow, M.R., Gao, S., O Neill, D.P., Saykin, A.J.

Source: JOURNAL OF ALZHEIMERS DISEASE. 35(4):751-760

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Reviewing the Role of Donepezil in the Treatment of Alzheimer's Disease

Authors: Doody, R.S., Cummings, J.L., Farlow, M.R.

Source: CURRENT ALZHEIMER RESEARCH. 9(7):773-781

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN316945622&indx=1&recIds=ETOCRN316945622

Genotype patterns at PICALM, CR1, BIN1, CLU, and APOE genes are associated with episodic memory

Authors: Barral, S., Bird, T., Goate, A., Farlow, M.R., Diaz-Arrastia, R., Bennett, D.A., Graff-Radford, N., Boeve, B.F., Sweet, R.A., Stern, Y.

Source: NEUROLOGY -MINNEAPOLIS-. 78(19):1464-1471

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In vivo and Postmortem Clinicoanatomical Correlations in Frontotemporal Dementia and Parkinsonism Linked to Chromosome 17
Alzheimer's disease and Parkinson's disease: progress and new perspectives; AD/PD

Authors: Ghetti, B., Spina, S., Murrell, J.R., Huey, E.D., Pietrini, P., Sweeney, B., Wassermann, E.M., Keohane, C., Farlow, M.R., Grafman, J.

Source: NEURO-DEGENERATIVE DISEASES. 5(3/4):215-217

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Differences in Medication Use in the Alzheimer's Disease Neuroimaging Initiative: Analysis of Baseline Characteristics

Authors: Epstein, N.U., Saykin, A.J., Risacher, S.L., Gao, S., Farlow, M.R., Alzheimer s Disease Neuroimaging Initiative (ADNI)

Source: DRUGS AND AGING. 27(8):677-686

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Effects of Oral Rivastigmine on Cognitive Domains in Mild-to-Moderate Alzheimer's Disease

Authors: Farlow, M.R., Cummings, J.L., Olin, J.T., Meng, X.

Source: AMERICAN JOURNAL OF ALZHEIMERS DISEASE AND OTHER DEMENTIAS. 25(4):347-352

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Safety and Changes in Plasma and Cerebrospinal Fluid Amyloid beta After a Single Administration of an Amyloid beta Monoclonal Antibody in Subjects With Alzheimer Disease

Authors: Siemers, E.R., Friedrich, S., Dean, R.A., Gonzales, C.R., Farlow, M.R., Paul, S.M., DeMattos, R.B.

Source: CLINICAL NEUROPHARMACOLOGY. 33(2):67-73

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Rivastigmine Transdermal Patch Skin Tolerability: Results of a 1-Year Clinical Trial in Patients with Mild-to-Moderate Alzheimer's Disease

Authors: Cummings, J.L., Farlow, M.R., Meng, X., Tekin, S., Olin, J.T.

Source: CLINICAL DRUG INVESTIGATION. 30(1):41-49

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A 25-week, open-label trial investigating rivastigmine transdermal patches with concomitant memantine in mild-to-moderate Alzheimer's disease: a post hoc analysis

Authors: Farlow, M.R., Alva, G., Meng, X., Olin, J.T.

Source: CURRENT MEDICAL RESEARCH AND OPINION. 26(2):263-270

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Correlation of Clinical Features With Argyrophilic Grains at Autopsy

Authors: Sabbagh, M.N., Sandhu, S.S., Farlow, M.R., Vedders, L., Shill, H.A., Caviness, J.N., Connor, D.J., Sue, L., Adler, C.H., Beach, T.G.

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Phase 2 Safety Trial Targeting Amyloid beta Production With a gamma -Secretase Inhibitor in Alzheimer Disease

Authors: Fleisher, A.S., Raman, R., Siemers, E.R., Becerra, L., Clark, C.M., Dean, R.A., Farlow, M.R., Galvin, J.E., Peskind, E.R., Quinn, J.F.

Source: ARCHIVES OF NEUROLOGY -CHIGAGO-. 65(8):1031-1040

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Memantine for the Treatment of Alzheimer's Disease: Tolerability and Safety Data from Clinical Trials

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Source: DRUG SAFETY. 31(7):577-585

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Multiple SNPs Within and Surrounding the Apolipoprotein E Gene Influence Cerebrospinal Fluid Apolipoprotein E Protein Levels

Authors: Bekris, L.M., Millard, S.P., Galloway, N.M., Vuletic, S., Albers, J.J., Li, G., Galasko, D.R., DeCarli, C., Farlow, M.R., Clark, C.M.

Source: JOURNAL OF ALZHEIMERS DISEASE. 13(3):255-266

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