Differential effects of familial Alzheimer’s disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity

Authors: Sandra Schilling, Ajay Pradhan, Amelie Heesch, Andrea Helbig, Kaj Blennow, Christian Koch, Lea Bertgen, Edward H. Koo, Gunnar Brinkmalm, Henrik Zetterberg, Stefan Kins, Simone Eggert

Source: Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-25 (2023)

Subject Terms: Alzheimer’s disease, Amyloid precursor protein, Familial Alzheimer disease, Beta Amyloid, Trafficking, Processing, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/a10b9eb7897345259b2c069974724e66

Mapping the genetic landscape of early-onset Alzheimer’s disease in a cohort of 36 families

Authors: Merel O. Mol, Sven J. van der Lee, Marc Hulsman, Yolande A. L. Pijnenburg, Phillip Scheltens, Netherlands Brain Bank, Harro Seelaar, John C. van Swieten, Laura Donker Kaat, Henne Holstege, Jeroen G. J. van Rooij

Source: Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2022)

Subject Terms: Alzheimer’s disease, Early-onset Alzheimer disease, Familial Alzheimer disease, Whole exome sequencing, Genetic testing, Genetic counseling, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1758-9193

Access URL: https://doaj.org/article/c8e6a06105dd443495870162989bb619

(−)-Epigallocatechin-3-Gallate Diminishes Intra-and Extracellular Amyloid-Induced Cytotoxic Effects on Cholinergic-like Neurons from Familial Alzheimer’s Disease PSEN1 E280A

Authors: Viviana Soto-Mercado, Miguel Mendivil-Perez, Carlos Velez-Pardo, Marlene Jimenez-Del-Rio

Source: Biomolecules, Vol 11, Iss 12, p 1845 (2021)

Subject Terms: cholinergic neurons, epigallocatechin-3-gallate, phytochemical, polyphenol, familial Alzheimer disease, PSEN1, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/11/12/1845; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/d6f197876d61427f8923e40928cec981

Biomarkers identification in Alzheimer’s disease using effective connectivity analysis from electroencephalography recordings

Authors: Jazmín X. Suárez-Revelo, John F. Ochoa-Gómez, Jon E. Duque-Grajales, Carlos A. Tobón-Quintero

Source: Ingeniería e Investigación, Vol 36, Iss 3, Pp 50-57 (2016)

Subject Terms: Familial Alzheimer disease, Electroencephalography, Effective connectivity, Brain graphs, Engineering (General). Civil engineering (General), TA1-2040

File Description: electronic resource

Relation: https://revistas.unal.edu.co/index.php/ingeinv/article/view/54037; https://doaj.org/toc/0120-5609; https://doaj.org/toc/2248-8723

Access URL: https://doaj.org/article/1ad31235f06f4208bc3dad9cb85ae56b

Age-related loss of phospholipid asymmetry in APPNLh/APPNLh x PS-1P264L/PS-1P264L human double mutant knock-in mice: Relevance to Alzheimer disease

Authors: Miranda L. Bader Lange, Daret St. Clair, William R. Markesbery, Christa M. Studzinski, M. Paul Murphy, D. Allan Butterfield

Source: Neurobiology of Disease, Vol 38, Iss 1, Pp 104-115 (2010)

Subject Terms: Amyloid precursor protein (APP), Presenilin-1 (PS-1), Familial Alzheimer disease (FAD), Phosphatidylserine (PtdSer), Phospholipid asymmetry, Oxidative stress, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996110000069; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/98b19aae5a2c40e69b84eb51b22f708a

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