A high affinity Sybody blocks Cofilin-1 binding to F-actin in vitro and in cancer cells

Authors: Paraschiakos, Themistoklis ^a, Li, Jing ^a, Scholz, Jonas ^b, Han, Soo-Ji ^a, Deckers, Markus ^a, Pogenberg, Vivian ^a, Faix, Jan ^b, Windhorst, Sabine ^{a, ⁎}

Source: In Biochemical Pharmacology June 2025 236

Epithelial restitution in 3D - Revealing biomechanical and physiochemical dynamics in intestinal organoids via fs laser nanosurgery

Authors: Donath, Sören, Seidler, Anna Elisabeth, Mundin, Karlina, Wenzel, Johannes, Scholz, Jonas, Gentemann, Lara, Kalies, Julia, Faix, Jan, Ngezahayo, Anaclet, Bleich, André, Heisterkamp, Alexander, Buettner, Manuela, Kalies, Stefan

Source: In iScience 17 November 2023 26(11)

Frameshift mutation S368fs in the gene encoding cytoskeletal β-actin leads to ACTB-associated syndromic thrombocytopenia by impairing actin dynamics

Authors: Greve, Johannes N., Schwäbe, Frederic V., Pokrant, Thomas, Faix, Jan, Di Donato, Nataliya, Taft, Manuel H., Manstein, Dietmar J.

Source: In European Journal of Cell Biology April 2022 101(2)

VASP boosts protrusive activity of macroendocytic cups and drives phagosome rocketing after internalization

Authors: Körber, Sarah, Faix, Jan

Source: In European Journal of Cell Biology April 2022 101(2)

Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion

Authors: Stahnke, Stephanie, Döring, Hermann, Kusch, Charly, de Gorter, David J.J., Dütting, Sebastian, Guledani, Aleks, Pleines, Irina, Schnoor, Michael, Sixt, Michael, Geffers, Robert, Rohde, Manfred, Müsken, Mathias, Kage, Frieda, Steffen, Anika, Faix, Jan, Nieswandt, Bernhard, Rottner, Klemens, Stradal, Theresia E.B.

Source: In Current Biology 24 May 2021 31(10):2051-2064

Capping protein is dispensable for polarized actin network growth and actin-based motility

Authors: Abou-Ghali, Majdouline, Kusters, Remy, Körber, Sarah, Manzi, John, Faix, Jan, Sykes, Cécile, Plastino, Julie ^*

Source: In Journal of Biological Chemistry 6 November 2020 295(45):15366-15375

Functional integrity of the contractile actin cortex is safeguarded by multiple Diaphanous-related formins

Authors: Litschko, Christof, Brühmann, Stefan, Csiszár, Agnes, Stephan, Till, Dimchev, Vanessa, Damiano-Guercio, Julia, Junemann, Alexander, Körber, Sarah, Winterhoff, Moritz, Nordholz, Benjamin, Ramalingam, Nagendran, Peckham, Michelle, Rottner, Klemens, Merkel, Rudolf, Faix, Jan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Feb . 116(9), 3594-3603.

Access URL: https://www.jstor.org/stable/26672108

IQGAP-related protein IqgC suppresses Ras signaling during large-scale endocytosis

Authors: Marinović, Maja, Mijanović, Lucija, Šoštar, Marko, Vizovišek, Matej, Junemann, Alexander, Fonović, Marko, Turk, Boris, Weber, Igor, Faix, Jan, Filić, Vedrana

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Jan . 116(4), 1289-1298.

Access URL: https://www.jstor.org/stable/26580240

Comprehensive Cell Biological Investigation of Cytochalasin B Derivatives with Distinct Activities on the Actin Network.

Authors: Kagho, Mervic D., Schmidt, Katharina, Lambert, Christopher, Kaufmann, Thomas, Jia, Lili, Faix, Jan, Rottner, Klemens, Stadler, Marc, Stradal, Theresia, Klahn, Philipp

Source: Journal of Natural Products; 10/25/2024, Vol. 87 Issue 10, p2421-2431, 11p

Distinct VASP tetramers synergize in the processive elongation of individual actin filaments from clustered arrays

Authors: Brühmann, Stefan, Ushakov, Dmitry S., Winterhoff, Moritz, Dickinson, Richard B., Curth, Ute, Faix, Jan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2017 Jul . 114(29), E5815-E5824.

Access URL: https://www.jstor.org/stable/26486698

Differential functions of WAVE regulatory complex subunits in the regulation of actin-driven processes

Authors: Litschko, Christof, Linkner, Joern, Brühmann, Stefan, Stradal, Theresia E.B., Reinl, Tobias, Jänsch, Lothar, Rottner, Klemens, Faix, Jan

Source: In European Journal of Cell Biology December 2017 96(8):715-727

Actomyosin organelle functions of SPIRE actin nucleators precede animal evolution.

Authors: Kollmar, Martin, Welz, Tobias, Ravi, Aishwarya, Kaufmann, Thomas, Alzahofi, Noura, Hatje, Klas, Alghamdi, Asmahan, Kim, Jiyu, Briggs, Deborah A., Samol-Wolf, Annette, Pylypenko, Olena, Hume, Alistair N., Burkhardt, Pawel, Faix, Jan, Kerkhoff, Eugen

Source: Communications Biology; 7/8/2024, Vol. 7 Issue 1, p1-21, 21p

Subject Terms: BIOLOGICAL evolution, ACTIN, CYTOSKELETAL proteins, MOLECULAR biology, ACTOMYOSIN

Detection of Subtle Phenotypes: The Case of the Cell Adhesion Molecule csA in Dictyostelium

Authors: Ponte, Eleonora, Bracco, Enrico, Faix, Jan, Bozzaro, Salvatore

Source: Proceedings of the National Academy of Sciences of the United States of America, 1998 Aug 01. 95(16), 9360-9365.

Access URL: https://www.jstor.org/stable/45479

Analysis of Random Migration of Dictyostelium Amoeba in Confined and Unconfined Environments

Authors: Litschko, Christof, Damiano-Guercio, Julia, Brühmann, Stefan, Faix, Jan

Source: Methods in molecular biology. 1749:341-350

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN615326019&indx=1&recIds=ETOCRN615326019

Capping protein-controlled actin polymerization shapes lipid membranes

Authors: Dürre, Katharina, Keber, Felix, Bleicher, Philip, Brauns, Fridtjof, Cyron, Christian, Faix, Jan, Bausch, Andreas

Source: Nature communications. 9(1):1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100133342822.0x000001&indx=1&recIds=ETOCvdc_100133342822.0x000001

A Diaphanous -related formin links Ras signaling directly to actin assembly in macropinocytosis and phagocytosis

Authors: Junemann, Alexander, Filić, Vedrana, Winterhoff, Moritz, Nordholz, Benjamin, Litschko, Christof, Schwellenbach, Helena, Stephan, Till, Weber, Igor, Faix, Jan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2016 Nov . 113(47), E7464-E7473.

Access URL: https://www.jstor.org/stable/26472605

Single-molecule microscopy of molecules tagged with GFP or RFP derivatives in mammalian cells using nanobody binders

Authors: Platonova, Evgenia, Winterflood, Christian M., Junemann, Alexander, Albrecht, David, Faix, Jan, Ewers, Helge

Source: In Methods 15 October 2015 88:89-97

Actin-Filament Disassembly: It Takes Two to Shrink Them Fast

Authors: Winterhoff, Moritz, Faix, Jan

Source: In Current Biology 1 June 2015 25(11):R450-R452

Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading

Authors: Böttcher, Ralph T., Veelders, Maik, Rombaut, Pascaline, Faix, Jan, Theodosiou, Marina, Stradal, Theresa E., Rottner, Klemens, Zent, Roy, Herzog, Franz, Fässler, Reinhard

Source: Journal of cell biology. 216(11):3785-3798

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN613547835&indx=1&recIds=ETOCRN613547835

EMC10 (Endoplasmic Reticulum Membrane Protein Complex Subunit 10) Is a Bone Marrow–Derived Angiogenic Growth Factor Promoting Tissue Repair After Myocardial Infarction

Authors: Reboll, Marc R., Korf-Klingebiel, Mortimer, Klede, Stefanie, Polten, Felix, Brinkmann, Eva, Reimann, Ines, Schönfeld, Hans-Joachim, Bobadilla, Maria, Faix, Jan, Kensah, George, Gruh, Ina, Klintschar, Michael, Gaestel, Matthias, Niessen, Hans W., Pich, Andreas, Bauersachs, Johann, Gogos, Joseph A., Wang, Yong, Wollert, Kai C.

Source: Circulation. 136(19):1809-1823

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050788662.0x000001&indx=1&recIds=ETOCvdc_100050788662.0x000001