Bi-isotype immunoglobulins enhance antibody-mediated neutrophil activity against Plasmodium falciparum parasites

Authors: Rodney Ogwang, Lewis Murugu, Irene N. Nkumama, Lydia Nyamako, Oscar Kai, Kennedy Mwai, Linda Murungi, Richard Idro, Philip Bejon, James Tuju, Sam Muchina Kinyanjui, Faith H. A. Osier

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: malaria, monoclonal antibodies, neutrophils, semi-immune, Kenya, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1360220/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3596a9cc7bec4318b00e63734a832347

Antibody-Dependent Respiratory Burst against Plasmodium falciparum Merozoites in Individuals Living in an Area with Declining Malaria Transmission

Authors: Doreen D. Mutemi, James Tuju, Rodney Ogwang, Lydia Nyamako, Kennedy M. Wambui, Ivette R. Cruz, Pär Villner, Victor Yman, Samson M. Kinyanjui, Ingegerd Rooth, Billy Ngasala, Anna Färnert, Faith H. A. Osier

Source: Vaccines, Vol 12, Iss 2, p 203 (2024)

Subject Terms: Plasmodium falciparum, malaria, transmission, ADRB, immunity, vaccines, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/12/2/203; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/b268b86836494599a872943934959601

Phagocytosis of Plasmodium falciparum ring-stage parasites predicts protection against malaria

Authors: Fauzia K. Musasia, Irene N. Nkumama, Roland Frank, Victor Kipkemboi, Martin Schneider, Kennedy Mwai, Dennis O. Odera, Micha Rosenkranz, Kristin Fürle, Domitila Kimani, James Tuju, Patricia Njuguna, Mainga Hamaluba, Melissa C. Kapulu, Hedda Wardemann, CHMI-SIKA Study Team, Faith H. A. Osier

Source: Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/05eca205b64046bc81c04d229ecba544

Characterization of a novel Plasmodium falciparum merozoite surface antigen and potential vaccine target

Authors: Karamoko Niaré, Timothy Chege, Micha Rosenkranz, Kennedy Mwai, Zoe Saßmannshausen, Dennis Odera, Lydia Nyamako, James Tuju, Tiono Alfred, John N. Waitumbi, Bernhards Ogutu, Sodiomon B. Sirima, Gordon Awandare, Bourema Kouriba, Julian C. Rayner, Faith H. A. Osier

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: Plasmodium falciparum malaria, PF3D7_1136200, ARMA, antigen diversity, IgG and IgM antibodies, vaccines, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1156806/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/8bd727a934b34249bd207e4d4cb957a2

Distinct kinetics of antibodies to 111 Plasmodium falciparum proteins identifies markers of recent malaria exposure

Authors: Victor Yman, James Tuju, Michael T. White, Gathoni Kamuyu, Kennedy Mwai, Nelson Kibinge, Muhammad Asghar, Christopher Sundling, Klara Sondén, Linda Murungi, Daniel Kiboi, Rinter Kimathi, Timothy Chege, Emily Chepsat, Patience Kiyuka, Lydia Nyamako, Faith H. A. Osier, Anna Färnert

Source: Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d52d616fbfd049d7ab986c391d76b171

Antibody responses to merozoite antigens after natural Plasmodium falciparum infection: kinetics and longevity in absence of re-exposure

Authors: Victor Yman, Michael T. White, Muhammad Asghar, Christopher Sundling, Klara Sondén, Simon J. Draper, Faith H. A. Osier, Anna Färnert

Source: BMC Medicine, Vol 17, Iss 1, Pp 1-14 (2019)

Subject Terms: Antibody, Half-life, Longevity, Traveller, Longitudinal, Malaria, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12916-019-1255-3; https://doaj.org/toc/1741-7015

Access URL: https://doaj.org/article/1f68f7df68b94d4187135082f59c75b7

Plasmodium falciparum Merozoite Associated Armadillo Protein (PfMAAP) Is Apically Localized in Free Merozoites and Antibodies Are Associated With Reduced Risk of Malaria

Authors: Yaw Aniweh, Prince B. Nyarko, Essel Charles-Chess, Felix Ansah, Faith H. A. Osier, Evelyn Quansah, Laty Gaye Thiam, Gathoni Kamuyu, Kevin Marsh, David J. Conway, Kevin K. A. Tetteh, Gordon A. Awandare

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: Malaria, armadillo, invasion, merozoites, antigen, antibodies, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.00505/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9c5e61c9efcd462e90d49b03c486d033

KILchip v1.0: A Novel Plasmodium falciparum Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization

Authors: Gathoni Kamuyu, James Tuju, Rinter Kimathi, Kennedy Mwai, James Mburu, Nelson Kibinge, Marisa Chong Kwan, Sam Hawkings, Reuben Yaa, Emily Chepsat, James M. Njunge, Timothy Chege, Fatuma Guleid, Micha Rosenkranz, Christopher K. Kariuki, Roland Frank, Samson M. Kinyanjui, Linda M. Murungi, Philip Bejon, Anna Färnert, Kevin K. A. Tetteh, James G. Beeson, David J. Conway, Kevin Marsh, Julian C. Rayner, Faith H. A. Osier

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: Plasmodium falciparum, merozoite, antibodies, vaccine candidates, protein microarray, bioinformatics, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.02866/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/5831dc4ac3f8459aafd4718c6ad4374f

Correction: Stable and Unstable Malaria Hotspots in Longitudinal Cohort Studies in Kenya.

Authors: Philip Bejon, Thomas N. Williams, Anne Liljander, Abdisalan M. Noor, Juliana Wambua, Edna Ogada, Ally Olotu, Faith H. A. Osier, Simon I. Hay, Anna Färnert, Kevin Marsh

Source: PLoS Medicine, Vol 8, Iss 2 (2011)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3045429/?tool=EBI; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/5269c0e25f834aa7be091d64f2c99da1

Exposure to multiple parasites is associated with the prevalence of active convulsive epilepsy in sub-Saharan Africa.

Authors: Gathoni Kamuyu, Christian Bottomley, James Mageto, Brett Lowe, Patricia P Wilkins, John C Noh, Thomas B Nutman, Anthony K Ngugi, Rachael Odhiambo, Ryan G Wagner, Angelina Kakooza-Mwesige, Seth Owusu-Agyei, Kenneth Ae-Ngibise, Honorati Masanja, Faith H A Osier, Peter Odermatt, Charles R Newton, Study of Epidemiology of Epilepsy in Demographic Sites (SEEDS) group

Source: PLoS Neglected Tropical Diseases, Vol 8, Iss 5, p e2908 (2014)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4038481?pdf=render; https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/b8d855699a6a441ba6cc68dbf1d5e7ec

The ratio of monocytes to lymphocytes in peripheral blood correlates with increased susceptibility to clinical malaria in Kenyan children.

Authors: George M Warimwe, Linda M Murungi, Gathoni Kamuyu, George M Nyangweso, Juliana Wambua, Vivek Naranbhai, Helen A Fletcher, Adrian V S Hill, Philip Bejon, Faith H A Osier, Kevin Marsh

Source: PLoS ONE, Vol 8, Iss 2, p e57320 (2013)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3577721?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6121631c297b4fee8a9870abcf44e77d

Stable and unstable malaria hotspots in longitudinal cohort studies in Kenya.

Authors: Philip Bejon, Thomas N Williams, Anne Liljander, Abdisalan M Noor, Juliana Wambua, Edna Ogada, Ally Olotu, Faith H A Osier, Simon I Hay, Anna Färnert, Kevin Marsh

Source: PLoS Medicine, Vol 7, Iss 7, p e1000304 (2010)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20625549/?tool=EBI; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/6784a10e6a1e4030a6dc307c291beb26

Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria.

Authors: Federica Verra, Jacques Simpore, George M Warimwe, Kevin K Tetteh, Tevis Howard, Faith H A Osier, Germana Bancone, Pamela Avellino, Isa Blot, Greg Fegan, Peter C Bull, Thomas N Williams, David J Conway, Kevin Marsh, David Modiano

Source: PLoS ONE, Vol 2, Iss 10, p e978 (2007)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC1991593?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/0eb468f537e74a9e9f43c2d67416f3bf