Cellular and enzymatic features of thrombi in humans are vascular bed dependent

Authors: Bender, Matthew T. ¹, Aggarwal, Anu ², Godwin, Matthew ², Guntupalli, Suman ², Nanjundappa, Aravinda ^{3, 4}, Tefera, Leben ⁴, Haddadin, Ihab ⁵, Tong, Michael ⁶, Baldwin, William M., III ⁷, Fairchild, Robert L. ⁷, Gomes, Marcelo ⁴, Campbell, Joseph ^{3, 4}, Schumick, David ², Chaudhury, Pulkit ⁴, Mix, Doran ^{8, ∗}, Cameron, Scott J. ^{2, 4, 9, 10, ∗∗}

Source: In Blood Vessels, Thrombosis & Hemostasis February 2025 2(1)

Marginal zone B cells are required for optimal humoral responses to allograft

Authors: Gorbacheva, Victoria, Fan, Ran, Gaudette, Brian, Baldwin, William M., III, Fairchild, Robert L., Valujskikh, Anna ^∗

Source: In American Journal of Transplantation January 2025 25(1):48-59

Spatial multiomics of arterial regions from cardiac allograft vasculopathy rejected grafts reveal novel insights into the pathogenesis of chronic antibody-mediated rejection

Authors: Nevarez-Mejia, Jessica, Pickering, Harry, Sosa, Rebecca A., Valenzuela, Nicole M., Fishbein, Gregory A., Baldwin, William M., III, Fairchild, Robert L., Reed, Elaine F.

Source: In American Journal of Transplantation July 2024 24(7):1146-1160

Human neutrophil peptides 1-3 protect the murine urinary tract from uropathogenic Escherichia coli challenge

Authors: Canas, Jorge J., Liang, Dong, Saxena, Vijay, Hooks, Jenaya, Arregui, Samuel W., Gao, Hongyu, Liu, Yunlong, Kish, Danielle, Linn, Sarah C., Bdeir, Khalil, Cines, Douglas B., Fairchild, Robert L., Spencer, John D., Schwaderer, Andrew L., Hains, David S.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Oct 01. 119(40), 1-10.

Access URL: https://www.jstor.org/stable/27208475

Human leukocyte antigen class I antibody-activated endothelium promotes CD206+ M2 macrophage polarization and MMP9 secretion through TLR4 signaling and P-selectin in a model of antibody-mediated rejection and allograft vasculopathy

Authors: Nevarez-Mejia, Jessica, Jin, Yi-Ping, Pickering, Harry, Parmar, Rajesh, Valenzuela, Nicole M., Sosa, Rebecca A., Heidt, Sebastiaan, Fishbein, Gregory A., Rozengurt, Enrique, Baldwin, William M., III, Fairchild, Robert L., Reed, Elaine F.

Source: In American Journal of Transplantation March 2024 24(3):406-418

Infliximab Induction Lacks Efficacy and Increases BK Virus Infection in Deceased Donor Kidney Transplant Recipients: Results of the CTOT-19 Trial

Authors: Hricik, Donald E., Armstrong, Brian, Alhamad, Tarek, Brennan, Daniel C., Bromberg, Jonathan S., Bunnapradist, Suphamai, Chandran, Sindhu, Fairchild, Robert. L., Foley, David P., Formica, Richard

Source: Journal of the American Society of Nephrology. 34(1):145-159

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632243659&indx=1&recIds=ETOCRN632243659

Autoantibodies against DNA topoisomerase I promote renal allograft rejection by increasing alloreactive T cell responses

Authors: Gorbacheva, Victoria, Fan, Ran, Miyairi, Satoshi, Fairchild, Robert L., Baldwin, William M., 3rd, Valujskikh, Anna

Source: In American Journal of Transplantation September 2023 23(9):1307-1318

Molecular Signature of Antibody-Mediated Chronic Vasculopathy in Heart Allografts in a Novel Mouse Model

Authors: Tsuda, Hidetoshi, Dvorina, Nina, Keslar, Karen S., Nevarez-Mejia, Jessica, Valenzuela, Nicole M., Reed, Elaine F., Fairchild, Robert L., Baldwin, William M.

Source: American journal of pathology. 192(7):1053-1065

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100166553549.0x000001&indx=1&recIds=ETOCvdc_100166553549.0x000001

Macrophage‐inducible C‐type lectin activates B cells to promote T cell reconstitution in heart allograft recipients

Authors: Hasgur, Suheyla, Yamamoto, Yosuke, Fan, Ran, Nicosia, Michael, Gorbacheva, Victoria, Zwick, Daniel, Araki, Motoo, Fairchild, Robert L., Valujskikh, Anna

Source: American journal of transplantation. 22(7):1779-1790

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154896037.0x000001&indx=1&recIds=ETOCvdc_100154896037.0x000001

Cardiac allograft tolerance can be achieved in nonhuman primates by donor bone marrow and kidney cotransplantation.

Authors: Tonsho, Makoto, O, Jane M., Ahrens, Kaitlan, Robinson, Kortney, Sommer, Wiebke, Boskovic, Svjetlan, Patel, Parth M., Becerra, David C., Huh, Kyu Ha, Miller, Cynthia L., Dehnadi, Abbas, Hanekamp, Isabel, Rosales, Ivy A., Colvin, Robert B., Sachs, David H., Alessandrini, Alessandro, Cosimi, Benedict, Fairchild, Robert L., Cravedi, Paolo, Bin, Sofia

Source: Science Translational Medicine; 1/22/2025, Vol. 17 Issue 782, p1-16, 16p

Subject Terms: BONE marrow transplantation, REGULATORY T cells, MAJOR histocompatibility complex, HEART transplantation, KIDNEY transplantation

C1q as a potential tolerogenic therapeutic in transplantation

Authors: Baldwin III, William M. ^*, Valujskikh, Anna, Fairchild, Robert L.

Source: In American Journal of Transplantation November 2021 21(11):3519-3523

Natural Killer Cells: Critical Effectors During Antibody-mediated Rejection of Solid Organ Allografts

Authors: Miyairi, Satoshi, Baldwin, William M., Valujskikh, Anna, Fairchild, Robert L.

Source: Transplantation. 105(2):284-290

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188366480.0x000001&indx=1&recIds=ETOCvdc_100188366480.0x000001

Painless Photodynamic Therapy Triggers Innate and Adaptive Immune Responses in a Murine Model of UV‐induced Squamous Skin Pre‐cancer

Authors: Anand, Sanjay, Govande, Mukul, Yasinchak, Anton, Heusinkveld, Lauren, Shakya, Sajina, Fairchild, Robert L., Maytin, Edward V.

Source: Photochemistry and photobiology. 97(3):607-617

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164604710.0x000001&indx=1&recIds=ETOCvdc_100164604710.0x000001

B cell–derived IL-1β and IL-6 drive T cell reconstitution following lymphoablation

Authors: Hasgur, Suheyla, Fan, Ran, Zwick, Daniel B., Fairchild, Robert L., Valujskikh, Anna ^*

Source: In American Journal of Transplantation October 2020 20(10):2740-2754

Antibody-induced vascular inflammation skews infiltrating macrophages to a novel remodeling phenotype in a model of transplant rejection

Authors: Wei, Xuedong, Valenzuela, Nicole M., Rossetti, Maura, Sosa, Rebecca A., Nevarez-Mejia, Jessica, Fishbein, Gregory A., Mulder, Arend, Dhar, Jayeeta, Keslar, Karen S., Baldwin, William M., III, Fairchild, Robert L., Hou, Jianquan, Reed, Elaine F. ^*

Source: In American Journal of Transplantation October 2020 20(10):2686-2702

Early T cell infiltration is modulated by programed cell death-1 protein and its ligand (PD-1/PD-L1) interactions in murine kidney transplants

Authors: Shim, Young Jun, Khedraki, Raneem, Dhar, Jayeeta, Fan, Ran, Dvorina, Nina, Valujskikh, Anna, Fairchild, Robert L., Baldwin, William M., III

Source: In Kidney International October 2020 98(4):897-905

The neonatal Fc receptor: Key to homeostasic control of IgG and IgG-related biopharmaceuticals

Authors: Baldwin, William M., III ^*, Valujskikh, Anna, Fairchild, Robert L.

Source: In American Journal of Transplantation July 2019 19(7):1881-1887

Peritransplant VLA-4 blockade inhibits endogenous memory CD8 T cell infiltration into high-risk cardiac allografts and CTLA-4Ig resistant rejection

Authors: Iida, Shoichi, Miyairi, Satoshi, Su, Charles A., Abe, Toyofumi, Abe, Ryo, Tanabe, Kazunari, Dvorina, Nina, Baldwin, William M., 3rd, Fairchild, Robert L. ^*

Source: In American Journal of Transplantation April 2019 19(4):998-1010

Spatial transcriptomics of Glomerulo-centric antibody mediated rejection in renal transplants

Authors: Margeta, Dajana ^a, Noguchi, Hirotsugu ^a, Khazaie, Sepideh ^a, Herlitz, Leal C. ^b, Augustine, Joshua J. ^c, Heeger, Peter S. ^d, Tambur, Anat R. ^e, Fairchild, Robert L. ^a, Baldwin, William M., III ^{a, ⁎}

Source: In Clinical Immunology May 2025 274

Machine perfusion in liver transplantation: recent advances and coming challenges.

Authors: Wehrle, Chase J., Jiao, Chunbao, Sun, Keyue, Zhang, Mingyi, Fairchild, Robert L., Miller, Charles, Hashimoto, Koji, Schlegel, Andrea

Source: Current Opinion in Organ Transplantation; Aug2024, Vol. 29 Issue 4, p228-238, 11p