Secretome of brain microvascular endothelial cells promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage

Authors: Rodrigo Azevedo Loiola, Johan Hachani, Sophie Duban-Deweer, Emmanuel Sevin, Paulina Bugno, Agnieszka Kowalska, Eleonora Rizzi, Fumitaka Shimizu, Takashi Kanda, Caroline Mysiorek, Maciej Mazurek, Fabien Gosselet

Source: Molecular Medicine, Vol 30, Iss 1, Pp 1-23 (2024)

Subject Terms: Brain microvascular endothelial cells, Secretome, Blood–brain barrier, Stroke, Angiogenesis, Cell therapy, Therapeutics. Pharmacology, RM1-950, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1528-3658

Access URL: https://doaj.org/article/3fdd9b198ef94d4688410eae49a4a9e2

Erratum for Gaume et al., 'Enterovirus A71 crosses a human blood–brain barrier model through infected immune cells'

Authors: Léa Gaume, Hélène Chabrolles, Maxime Bisseux, Igor Lopes Coqueiro, Lucie Dehouck, Audrey Mirand, Cécile Henquell, Fabien Gosselet, Christine Archimbaud, Jean-Luc Bailly

Source: Microbiology Spectrum, Vol 12, Iss 11 (2024)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/842f63a2d8c148578221c91aee18e6f9

Erratum to 'CD31 orchestrates metabolic regulation in autophagy pathways of rheumatoid arthritis' [Pharmacol. Res. 207 (2024) 107346]

Authors: Kenneth CP Cheung, Jiao Ma, Lu Wang, Xingxuan Chen, Silvia Fanti, Mingzhang Li, Loiola Rodrigo Azevedo, Fabien Gosselet, Hao Shen, Xiaojiao Zheng, Aiping Lu, Wei Jia

Source: Pharmacological Research, Vol 208, Iss , Pp 107366- (2024)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1043661824003116; https://doaj.org/toc/1096-1186

Access URL: https://doaj.org/article/872d356fde6546e09a2d5f8c7936f634

Investigation of Lysophospholipids-DHA transport across an in vitro human model of blood brain barrier

Authors: Mayssa Hachem, Abdelmoneim H. Ali, Ibrahim Yildiz, Christophe Landry, Fabien Gosselet

Source: Heliyon, Vol 10, Iss 19, Pp e38871- (2024)

Subject Terms: Brain lipids, Omega-3 fatty acids, Docosahexaenoic acid, Lysophospholipids, Fatty acid transport, Blood-brain-barrier, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S240584402414902X; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/3d3bb15b552844418f7843628258dcdc

CD31 orchestrates metabolic regulation in autophagy pathways of rheumatoid arthritis

Authors: Kenneth CP Cheung, Jiao Ma, Lu Wang, Xingxuan Chen, Silvia Fanti, Mingzhang Li, Loiola Rodrigo Azevedo, Fabien Gosselet, Hao Shen, Xiaojiao Zheng, Aiping Lu, Wei Jia

Source: Pharmacological Research, Vol 207, Iss , Pp 107346- (2024)

Subject Terms: Endothelium, Rheumatoid arthritis, Inflammation, Autophagy, CD31, Glycolysis and oxidative phosphorylation, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1043661824002913; https://doaj.org/toc/1096-1186

Access URL: https://doaj.org/article/96338ddeb28749188db38d0f58d81ac4

ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells

Authors: Julien Cicero, Sarah Trouvilliez, Martine Palma, Gaetan Ternier, Laurine Decoster, Eloise Happernegg, Nicolas Barois, Alexandre Van Outryve, Lucie Dehouck, Roland P. Bourette, Eric Adriaenssens, Chann Lagadec, Cagatay Mehmet Tarhan, Dominique Collard, Zied Souguir, Elodie Vandenhaute, Grégory Maubon, François Sipieter, Nicolas Borghi, Fumitaka Shimizu, Takashi Kanda, Paolo Giacobini, Fabien Gosselet, Nathalie Maubon, Xuefen Le Bourhis, Isabelle Van Seuningen, Caroline Mysiorek, Robert-Alain Toillon

Source: Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-20 (2023)

Subject Terms: proNGF, TrkA, EphA2, Src, Brain metastasis, Breast cancer, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3619

Access URL: https://doaj.org/article/a669d848d8994ea18bb634e2c30e3e37

Enterovirus A71 crosses a human blood–brain barrier model through infected immune cells

Authors: Léa Gaume, Hélène Chabrolles, Maxime Bisseux, Igor Lopez-Coqueiro, Lucie Dehouck, Audrey Mirand, Cécile Henquell, Fabien Gosselet, Christine Archimbaud, Jean-Luc Bailly

Source: Microbiology Spectrum, Vol 12, Iss 6 (2024)

Subject Terms: neuroinvasion, EV-A71 neurotropism, blood–brain barrier model, BBB crossing, white blood cells, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2165-0497

Access URL: https://doaj.org/article/e9a1f0fdf2174ad882d99b9c407f3dd3

25-Hydroxycholesterol in health and diseases

Authors: Cindy Nguyen, Julien Saint-Pol, Shiraz Dib, Caroline Pot, Fabien Gosselet

Source: Journal of Lipid Research, Vol 65, Iss 1, Pp 100486- (2024)

Subject Terms: 25-hydroxycholesterol, oxysterols, 7α,25-dihydroxycholesterol, cholesterol, reverse cholesterol transfer, ABCA1, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227523001591; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/ae6afaa77bd845bfbb816d3d13e227b5

High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro

Authors: Sasha Soldati, Alexander Bär, Mykhailo Vladymyrov, Dale Glavin, James L. McGrath, Fabien Gosselet, Hideaki Nishihara, Susan Goelz, Britta Engelhardt

Source: Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-22 (2023)

Subject Terms: Blood–brain barrier, Brain microvascular endothelial cells, Central nervous system, Extended interval dosing, Intercellular adhesion molecule-1, Multiple sclerosis, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/ac48d8c3d465490f8a3c4c2f105b86bd

Retraction Note: Secretome of endothelial progenitor cells from stroke patients promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage

Authors: Rodrigo Azevedo Loiola, Miguel García-Gabilondo, Alba Grayston, Paulina Bugno, Agnieszka Kowalska, Sophie Duban-Deweer, Eleonora Rizzi, Johan Hachani, Yasuteru Sano, Fumitaka Shimizu, Takashi Kanda, Caroline Mysiorek, Maciej Piotr Mazurek, Anna Rosell, Fabien Gosselet

Source: Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-1 (2024)

Subject Terms: Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/582b6f18710d45b1a3951d77304dd233

Enhancing Oral Delivery of Biologics: A Non-Competitive and Cross-Reactive Anti-Leptin Receptor Nanofitin Demonstrates a Gut-Crossing Capacity in an Ex Vivo Porcine Intestinal Model

Authors: Solene Masloh, Anne Chevrel, Maxime Culot, Anaëlle Perrocheau, Yogeshvar N. Kalia, Samuel Frehel, Rémi Gaussin, Fabien Gosselet, Simon Huet, Magali Zeisser Labouebe, Leonardo Scapozza

Source: Pharmaceutics, Vol 16, Iss 1, p 116 (2024)

Subject Terms: biotherapeutics, permeability, shuttle, leptin receptor, Nanofitins, ex vivo, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/16/1/116; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/4b4bcb36b0234098a1e1c6b287e87672

Direct interaction of TrkA/CD44v3 is essential for NGF-promoted aggressiveness of breast cancer cells

Authors: Sarah Trouvilliez, Julien Cicero, Romain Lévêque, Léo Aubert, Cyril Corbet, Alexandre Van Outryve, Karolin Streule, Pierre-Olivier Angrand, Pamela Völkel, Romain Magnez, Guillaume Brysbaert, Caroline Mysiorek, Fabien Gosselet, Roland Bourette, Eric Adriaenssens, Xavier Thuru, Chann Lagadec, Jérôme de Ruyck, Véronique Orian-Rousseau, Xuefen Le Bourhis, Robert-Alain Toillon

Source: Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-21 (2022)

Subject Terms: CD44v3, TrkA, NGF, Breast cancer, Metastasis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/ee062cffb44348f899eaf1616d8c4bf4

Vesicular Trafficking, a Mechanism Controlled by Cascade Activation of Rab Proteins: Focus on Rab27

Authors: Camille Menaceur, Océane Dusailly, Fabien Gosselet, Laurence Fenart, Julien Saint-Pol

Source: Biology, Vol 12, Iss 12, p 1530 (2023)

Subject Terms: RabGTPase, vesicular trafficking, extracellular vesicles, Rab27a, Rab27b, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2079-7737/12/12/1530; https://doaj.org/toc/2079-7737

Access URL: https://doaj.org/article/2d25aaf157ea42298cba6491450e3240

RETRACTED ARTICLE: Secretome of endothelial progenitor cells from stroke patients promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage

Authors: Rodrigo Azevedo Loiola, Miguel García-Gabilondo, Alba Grayston, Paulina Bugno, Agnieszka Kowalska, Sophie Duban-Deweer, Eleonora Rizzi, Johan Hachani, Yasuteru Sano, Fumitaka Shimizu, Takashi Kanda, Caroline Mysiorek, Maciej Piotr Mazurek, Anna Rosell, Fabien Gosselet

Source: Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-23 (2021)

Subject Terms: Endothelial progenitor cells, Secretome, Blood–brain barrier, Stroke, Angiogenesis, Cell therapy, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/ea8069f07ba549acada77b41d8b7f5b0

Correction to: Differential neurovirulence of Usutu viruslineages in mice and neuronal cells

Authors: Marion Clé, Orianne Constant, Jonathan Barthelemy, Caroline Desmetz, Marie France Martin, Lina Lapeyre, Daniel Cadar, Giovanni Savini, Liana Teodori, Federica Monaco, Jonas Schmidt-Chanasit, Juan-Carlos Saiz, Gaëlle Gonzales, Sylvie Lecollinet, Cécile Beck, Fabien Gosselet, Philippe Van de Perre, Vincent Foulongne, Sara Salinas, Yannick Simonin

Source: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-4 (2021)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/c056e29878084cd79b0a00cbb45e2836

Differential neurovirulence of Usutu virus lineages in mice and neuronal cells

Authors: Marion Clé, Orianne Constant, Jonathan Barthelemy, Caroline Desmetz, Marie France Martin, Lina Lapeyre, Daniel Cadar, Giovanni Savini, Liana Teodori, Federica Monaco, Jonas Schmidt-Chanasit, Juan-Carlos Saiz, Gaëlle Gonzales, Sylvie Lecollinet, Cécile Beck, Fabien Gosselet, Philippe Van de Perre, Vincent Foulongne, Sara Salinas, Yannick Simonin

Source: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-22 (2021)

Subject Terms: Usutu virus, Arbovirus, Flavivirus, Neurotropism, Central nervous system, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/d7cdfbaeec5a41758f443179c4b5fcf6

Caspase-1 has a critical role in blood-brain barrier injury and its inhibition contributes to multifaceted repair

Authors: Hila Israelov, Orly Ravid, Dana Atrakchi, Daniel Rand, Shirin Elhaik, Yael Bresler, Rachel Twitto-Greenberg, Liora Omesi, Sigal Liraz-Zaltsman, Fabien Gosselet, Michal Schnaider Beeri, Itzik Cooper

Source: Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-19 (2020)

Subject Terms: Caspase-1, Inflammasome, Blood-brain barrier, Paraoxon, Permeability, Adhesion, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12974-020-01927-w; https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/0fb820df750949eeb24a86b3cdf76c1e

Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells

Authors: Marjolein Heymans, Ricardo Figueiredo, Lucie Dehouck, David Francisco, Yasuteru Sano, Fumitaka Shimizu, Takashi Kanda, Rémy Bruggmann, Britta Engelhardt, Peter Winter, Fabien Gosselet, Maxime Culot

Source: Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-28 (2020)

Subject Terms: Blood–brain barrier1, Transcriptome2, BBB formation3, In vitro4, Central nervous system5, Brain endothelial cells6, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12987-020-00208-1; https://doaj.org/toc/2045-8118

Access URL: https://doaj.org/article/55e1fbd5ebc84630ac0ce3c232be8cdb

Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance

Authors: Clémence Deligne, Johan Hachani, Sophie Duban-Deweer, Samuel Meignan, Pierre Leblond, Angel M. Carcaboso, Yasuteru Sano, Fumitaka Shimizu, Takashi Kanda, Fabien Gosselet, Marie-Pierre Dehouck, Caroline Mysiorek

Source: Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-15 (2020)

Subject Terms: Blood–brain barrier, Blood–brain tumor barrier, Diffuse intrinsic pontine glioma, Chemoresistance, Pediatric brain cancer, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12987-020-00198-0; https://doaj.org/toc/2045-8118

Access URL: https://doaj.org/article/498ffa16ab464982bbfc8abfc1891de8

Serum-derived factors of breast cancer patients with brain metastases alter permeability of a human blood–brain barrier model

Authors: Carolin J. Curtaz, Constanze Schmitt, Saskia-Laureen Herbert, Jonas Feldheim, Nicolas Schlegel, Fabien Gosselet, Carsten Hagemann, Norbert Roewer, Patrick Meybohm, Achim Wöckel, Malgorzata Burek

Source: Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-12 (2020)

Subject Terms: Metastatic breast cancer, Blood–brain barrier, In vitro models, CX3CL1, CXCL13, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12987-020-00192-6; https://doaj.org/toc/2045-8118

Access URL: https://doaj.org/article/f2affebe284d4521b882a8184eaa782c