Candidate genes associated with fatty acid compositions in north American Atlantic salmon (Salmo salar)

Authors: Barbara L. Langille, Manuel Juárez, Nuria Prieto, Solomon Boison, Panya Sae Lim, Bruce D. Swift, Amber F. Garber

Source: BMC Genomics, Vol 25, Iss 1, Pp 1-13 (2024)

Subject Terms: Fatty acid, Omega, Selective breeding, fads2, Biotechnology, TP248.13-248.65, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2164

Access URL: https://doaj.org/article/703a6849f5144664a0d0bc9714a17428

Fatty acid desaturase 2 (FADS2) affects the pluripotency of hESCs by regulating energy metabolism

Authors: Li, Zihong ¹, Li, Wei ¹, Zhang, Chenchen, Wang, Jing, Geng, Xiaoxiong, Qu, Burong, Yue, Yongli, Li, Xueling ^⁎

Source: In International Journal of Biological Macromolecules March 2025 295

Genome-wide identification and functional characterization of fatty acyl desaturase (fads2) gene in Chinese sturgeon (Acipenser sinensis)

Authors: Haoze Ding, Yacheng Hu, Pei Chen, Xin Zhu, Binzhong Wang, Chao Cheng, Tian Tian, Dezhi Zhang, Shuqi Wang, Yang Li

Source: Aquaculture Reports, Vol 38, Iss , Pp 102338- (2024)

Subject Terms: fads2, Functional characterization, LC-PUFAs biosynthesis, Chinese sturgeon (Acipenser sinensis), Chondrichthyans, Aquaculture. Fisheries. Angling, SH1-691

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352513424004265; https://doaj.org/toc/2352-5134

Access URL: https://doaj.org/article/31687ba7ea204c7d85a0daa91257ecfd

Fads2 knockout mice reveal that ALA prevention of hepatic steatosis is dependent on delta-6 desaturase activity

Authors: Blair MacLeod, Chenxuan Wang, Liam H. Brown, Emma Borkowski, Manabu T. Nakamura, Kyle RD. Wells, Keith R. Brunt, Ewa Harasim-Symbor, Adrian Chabowski, David M. Mutch

Source: Journal of Lipid Research, Vol 65, Iss 10, Pp 100642- (2024)

Subject Terms: delta-6 desaturase, gene expression, glyceroneogenesis, Fads2, fish oil, lipogenesis, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227524001470; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/7d06e0fec0d945ba98cf666b178b776f

Mitochondrial metabolism-related features guiding precision subtyping and prognosis in breast cancer, revealing FADS2 as a novel therapeutic target

Authors: Kang, Yakun ^{a, c, 1}, Meng, You ^{b, 1}, Jin, Jiangdong ^{a, 1}, Dai, Yuhan ^{a, 1}, Li, Fei ^d, Chen, Nuo ^d, Xie, Hui ^{a, ⁎}, Cui, Yangyang ^{a, ⁎}

Source: In Translational Oncology April 2025 54

FADS2 confers SCD1 inhibition resistance to cancer cells by modulating the ER stress response

Authors: Toshikatsu Ikeda, Yuki Katoh, Hirotsugu Hino, Daichi Seta, Tadashi Ogawa, Takashi Iwata, Hiroshi Nishio, Masaki Sugawara, Shuichi Hirai

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)

Subject Terms: Stearoyl-CoA desaturase 1 (SCD1), Fatty acid desaturase 2 (FADS2), Endoplasmic reticulum (ER) stress, Palmitic acid, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/f3aa575b4baa416fbc0f3b6f8f9c264e

Association of fatty acid desaturase 2 gene polymorphism (rs28456) with susceptibility to bipolar disorder in the Turkish population: A case-control study

Authors: Pirim Dilek, Gümüş Ceren, Boztepe Esra, Akdağ Emine Merve, Şirin Hande

Source: Archives of Biological Sciences, Vol 76, Iss 4, Pp 387-397 (2024)

Subject Terms: fatty acid desaturase 2 (fads2), bipolar disorder, rs28456, polyunsaturated fatty acids, pufa, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/0354-4664; https://doaj.org/toc/1821-4339

Access URL: https://doaj.org/article/5c873ab5ddd2439a8931b5fafae6b96c

Emerging roles of polyunsaturated fatty acid synthesis pathway in colorectal cancer

Authors: Young-Ah Moon

Source: Animal Cells and Systems, Vol 27, Iss 1, Pp 61-71 (2023)

Subject Terms: colorectal cancer, polyunsaturated fatty acid, ELOVL5, FADS2, arachidonic acid, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1976-8354; https://doaj.org/toc/2151-2485

Access URL: https://doaj.org/article/89efc3c2dc2040f2a3aae516b75ef9f6

Interaction among dietary n‐3 and n‐6 polyunsaturated fatty acid intake, fatty acid desaturase 2 genetic variants, and low‐density lipoprotein cholesterol levels in type 2 diabetes patients

Authors: Pei‐Chi Huang, Hsuan Cheng, Yu‐Ting Su, Meng‐Chuan Huang, Chih‐Cheng Hsu, Shang‐Jyh Hwang, Shyi‐Jang Shin, Wen‐Tsan Chang

Source: Journal of Diabetes Investigation, Vol 14, Iss 2, Pp 297-308 (2023)

Subject Terms: Diabetes, FADS1, FADS2, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://doaj.org/toc/2040-1116; https://doaj.org/toc/2040-1124

Access URL: https://doaj.org/article/1c5aa1cd80ab45a9a8ded8be325824d7

The role of fatty acid desaturase 2 in multiple tumor types revealed by bulk and single-cell transcriptomes

Authors: Enli Chen, Cong Wang, Hongwei Lv, Jing Yu

Source: Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-17 (2023)

Subject Terms: FADS2, Pan-cancer analysis, Biomarker, Prognosis, Immunotherapy, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://doaj.org/toc/1476-511X

Access URL: https://doaj.org/article/6eb795c01e7c4794ab5dcc78404da9f2

Delta-6 desaturase (Fads2) deficiency alters triacylglycerol/fatty acid cycling in murine white adipose tissue

Authors: Chenxuan Wang, Barbora Hucik, Ousseynou Sarr, Liam H. Brown, Kyle R.D. Wells, Keith R. Brunt, Manabu T. Nakamura, Ewa Harasim-Symbor, Adrian Chabowski, David M. Mutch

Source: Journal of Lipid Research, Vol 64, Iss 6, Pp 100376- (2023)

Subject Terms: delta-6 desaturase, Fads2, triacylglycerol, lipolysis, lipogenesis, omega-3 fatty acids, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227523000494; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/03285ef0270040c3b186ceb9e6e46e07

GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide

Authors: Sweta Parik, Juan Fernández-García, Francesca Lodi, Karen De Vlaminck, Marleen Derweduwe, Steven De Vleeschouwer, Raf Sciot, Wietse Geens, Linqian Weng, Francesca Maria Bosisio, Gabriele Bergers, Johnny Duerinck, Frederick De Smet, Diether Lambrechts, Jo A. Van Ginderachter, Sarah-Maria Fendt

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: glioblastoma, fatty acid metabolism, lipotoxicity, SCD1, FADS2, tumor heterogeneity, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.988872/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/9b367757c6e54473af57787cad0920a8

Stearoyl-CoA desaturase (scd1a) is epigenetically regulated by broodstock nutrition in gilthead sea bream (Sparus aurata)

Authors: Erick Perera, Serhat Turkmen, Paula Simó-Mirabet, Maria J. Zamorano, Hanlin Xu, Fernando Naya-Català, Marisol Izquierdo, Jaume Pérez-Sánchez

Source: Epigenetics, Vol 15, Iss 5, Pp 536-553 (2020)

Subject Terms: broodstock feeding, dna methylation, fads2, linolenic acid, nutritional programing, scd1, sparus aurata, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1559-2294; https://doaj.org/toc/1559-2308

Access URL: https://doaj.org/article/1f57182b24d54ec09711ab4485375c8d

Elevation of fatty acid desaturase 2 in esophageal adenocarcinoma increases polyunsaturated lipids and may exacerbate bile acid‐induced DNA damage

Authors: Jeffrey Molendijk, Cathryn M. Kolka, Henry Cairns, Sandra Brosda, Ahmed Mohamed, Alok K. Shah, Ian Brown, Mark P. Hodson, Thomas Hennessy, Guanghao Liu, Thomas Stoll, Renee S. Richards, Michael Gartside, Kalpana Patel, Nicholas J. Clemons, Wayne A. Phillips, Andrew Barbour, Johan A. Westerhuis, Michelle M. Hill

Source: Clinical and Translational Medicine, Vol 12, Iss 5, Pp n/a-n/a (2022)

Subject Terms: Barrett's esophagus, esophageal adenocarcinoma, FADS2, lipid desaturation, lipid metabolism, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/83267b7d1c744d739752ec479435fbf3

Duration of the flaxseed diet promotes deposition of n-3 fatty acids in the meat and skin of Peking ducks

Authors: Muhammad Suhaib Shahid, Yuqin Wu, Zhibin Xiao, Tausif Raza, Xiaoyu Dong, Jianmin Yuan

Source: Food & Nutrition Research, Vol 63, Iss 0, Pp 1-11 (2019)

Subject Terms: flaxseed, lpin-1, fads2, dha, meat, duck, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://foodandnutritionresearch.net/index.php/fnr/article/view/3590/9646; https://doaj.org/toc/1654-661X

Access URL: https://doaj.org/article/55a3755dc3d14aa1a78c53ea2035ff39

Investigation of FADS Gene Cluster Single Nucleotide Polymorphisms in End-Stage Renal Disease Compared With Normal Controls

Authors: Amirhossein Miladipour, Mahdi Gholipour, Kasra Honarmand Tamizkar, Atefe Abak, Vahid Kholghi Oskooei, Mohammad Taheri, Soudeh Ghafouri-Fard

Source: Frontiers in Genetics, Vol 12 (2021)

Subject Terms: FADS1, FADS2, FADS3, polymorphisms, hemodialysis, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2021.716151/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/262282c8277e47bba74c3289086779a3

The g.4290 C>G Polymorphism in the FADS2 Gene Modifies the Fatty Acid Profile of the Pectoralis Superficialis Muscle of Ross 308 Broiler Chickens

Authors: Urszula Kaczor, Sebastian Sawicki, Joanna Nowak, Julia Gabryś, Jakub Jurczyk, Dorota Wojtysiak, Katarzyna Połtowicz

Source: Animals, Vol 12, Iss 15, p 1882 (2022)

Subject Terms: FADS2, FABP4, gene polymorphism, meat quality, fatty acids, broiler chicken, Veterinary medicine, SF600-1100, Zoology, QL1-991

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2615/12/15/1882; https://doaj.org/toc/2076-2615

Access URL: https://doaj.org/article/497267501d034670be292fb5ad35801a

Dietary ω3-and ω6-Polyunsaturated fatty acids reconstitute fertility of Juvenile and adult Fads2-Deficient mice

Authors: Wilhelm Stoffel, Inga Schmidt-Soltau, Erika Binczek, Andreas Thomas, Mario Thevis, Ina Wegner

Source: Molecular Metabolism, Vol 36, Iss , Pp - (2020)

Subject Terms: ω3-and ω6-PUFA deficiency, Auxotrophic fads2−/− mouse, Nutritional rescue of female and male fertility, Remodeling of membrane lipidomes, Reconstitution of junction systems of ovary and testis, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877820300478; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/a4f64f4355164be082ac421508a22c51

Liver DNA methylation of FADS2 associates with FADS2 genotypex

Authors: Paula Walle, Ville Männistö, Vanessa Derenji de Mello, Maija Vaittinen, Alexander Perfilyev, Kati Hanhineva, Charlotte Ling, Jussi Pihlajamäki

Source: Clinical Epigenetics, Vol 11, Iss 1, Pp 1-9 (2019)

Subject Terms: Non-alcoholic fatty liver disease, FADS2, DNA methylation, Epigenetics, mRNA expression, Liver, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13148-019-0609-1; https://doaj.org/toc/1868-7075; https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/81ddad4a975c41e5a7997c50d810dfab

Dietary fish oil and flaxseed for rabbit does: fatty acids distribution and Δ6-desaturase enzyme expression of different tissues

Authors: S. Mattioli, A. Dal Bosco, M. Maranesi, L. Petrucci, P.G. Rebollar, C. Castellini

Source: Animal, Vol 13, Iss 9, Pp 1934-1942 (2019)

Subject Terms: rabbit, n-3 long-chain fatty acids, FADS2, liver, ovary, Animal culture, SF1-1100

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S175173111900020X; https://doaj.org/toc/1751-7311

Access URL: https://doaj.org/article/726237184cd44c4282cbfaf98600d1c7