Dorsal root ganglion inflammation by oxaliplatin toxicity: DPEP1 as possible target for peripheral neuropathy prevention

Authors: Karen Álvarez-Tosco, Rebeca González-Fernández, María Ángeles González-Nicolás, Rita Martín-Ramírez, Manuel Morales, Ricardo Gutiérrez, Lucio Díaz-Flores, María Rosa Arnau, Félix Machín, Julio Ávila, Alberto Lázaro, Pablo Martín-Vasallo

Source: BMC Neuroscience, Vol 25, Iss 1, Pp 1-12 (2024)

Subject Terms: Dorsal root ganglion (DRG), Oxaliplatin, Neurotoxicity, DRG-inflammation, Dehydropeptidase-1 (DPEP1), Allodynia, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurophysiology and neuropsychology, QP351-495

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2202

Access URL: https://doaj.org/article/acf9d791df474243b76dec870eafa21b

Fused oxazepine-naphthoquinones as novel cytotoxic agents with diverse modes of action in yeast

Authors: Laura Anaissi-Afonso, Silvia Santana-Sosa, Isabel Lorenzo-Castrillejo, Grant McNaughton-Smith, Félix Machín

Source: Heliyon, Vol 10, Iss 24, Pp e41105- (2024)

Subject Terms: Benzoxazepine, naphthoquinone, Saccharomyces cerevisiae, Oxidative stress, cell cycle, Nucleolus, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024171368; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/e595300c33444add83339e52649d2904

Msc1 is a nuclear envelope protein that reinforces DNA repair in late mitosis

Authors: Sara Medina-Suárez, Jessel Ayra-Plasencia, Lara Pérez-Martínez, Falk Butter, Félix Machín

Source: iScience, Vol 27, Iss 7, Pp 110250- (2024)

Subject Terms: Biological sciences, Molecular biology, Cell biology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224014755; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/caa75a24e2ff430db9602a22bb5853b5

Topoisomerase II deficiency leads to a postreplicative structural shift in all Saccharomyces cerevisiae chromosomes

Authors: Jessel Ayra-Plasencia, Cristina Ramos-Pérez, Silvia Santana-Sosa, Oliver Quevedo, Sara Medina-Suárez, Emiliano Matos-Perdomo, Marcos Zamora-Dorta, Grant W. Brown, Michael Lisby, Félix Machín

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/7c08ad1d2a4f43afa57021c0e2001c32

DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci

Authors: Jessel Ayra-Plasencia, Félix Machín

Source: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/056a736d2c904c838127babaa2080374

Genome-Scale Genetic Interactions and Cell Imaging Confirm Cytokinesis as Deleterious to Transient Topoisomerase II Deficiency in Saccharomyces cerevisiae

Authors: Cristina Ramos-Pérez, Jessel Ayra-Plasencia, Emiliano Matos-Perdomo, Michael Lisby, Grant W. Brown, Félix Machín

Source: G3: Genes, Genomes, Genetics, Vol 7, Iss 10, Pp 3379-3391 (2017)

Subject Terms: topoisomerase II, top2-4 and top2-5, synthetic genetic array analysis, mitotic exit network, cytokinesis, plasma membrane abscission, anaphase bridges, Cdc14, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/2160-1836

Access URL: https://doaj.org/article/9406f5a7150f4e748fd3e3df211a570b

Yeast cells can partially revert chromosome segregation to repair late DNA double-strand breaks through homologous recombination

Authors: Jessel Ayra-Plasencia, Félix Machín

Source: Molecular & Cellular Oncology, Vol 6, Iss 5 (2019)

Subject Terms: dna double-strand breaks, homologous recombination, chromosome segregation, kinesin, telophase, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2372-3556

Access URL: https://doaj.org/article/31fa9fd73b6c43d2bc944f1ef6c361db

Efficient Multicomponent Synthesis of Diverse Antibacterial Embelin-Privileged Structure Conjugates

Authors: Pedro Martín-Acosta, Rosalyn Peña, Gabriela Feresin, Alejandro Tapia, Isabel Lorenzo-Castrillejo, Félix Machín, Ángel Amesty, Ana Estévez-Braun

Source: Molecules, Vol 25, Iss 14, p 3290 (2020)

Subject Terms: embelin, multicomponent reactions, privileged structure, antimicrobial activity, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/14/3290; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/af48bab38d834f37a2f8b0503e07d072

Publisher Correction: DNA double-strand breaks in telophase lead to coalescence between segregated sister chromatid loci

Authors: Jessel Ayra-Plasencia, Félix Machín

Source: Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/93077bd44fb24381a002a68d446cf8ca

Nucleolar and Ribosomal DNA Structure under Stress: Yeast Lessons for Aging and Cancer

Authors: Emiliano Matos-Perdomo, Félix Machín

Source: Cells, Vol 8, Iss 8, p 779 (2019)

Subject Terms: yeast nucleolus, yeast rDNA, nucleolar stress, TORC1, ribosome biogenesis, sirtuins, nucleolar condensation, aging, cancer, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/8/8/779; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/564d4d87884546618d7031fd408e6272

Yeasts acquire resistance secondary to antifungal drug treatment by adaptive mutagenesis.

Authors: David Quinto-Alemany, Ana Canerina-Amaro, Luís G Hernández-Abad, Félix Machín, Floyd E Romesberg, Cristina Gil-Lamaignere

Source: PLoS ONE, Vol 7, Iss 7, p e42279 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3409178?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/00fe170902ec4f74a5c2ead01b0fbfc2

Nondisjunction of a single chromosome leads to breakage and activation of DNA damage checkpoint in G2.

Authors: Oliver Quevedo, Jonay García-Luis, Emiliano Matos-Perdomo, Luis Aragón, Félix Machín

Source: PLoS Genetics, Vol 8, Iss 2, p e1002509 (2012)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3280967?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/b6b35368c98d499e84cbf4b4a645b9b8

No Role of HomologousRecombination in Dealing withβ-Lapachone Cytotoxicity in Yeast.

Authors: Oliver Quevedo, Jonay García-Luis, Isabel Lorenzo-Castrillejo, Félix Machín

Source: Chemical Research in Toxicology; Dec2011, Vol. 24 Issue 12, p2106-2108, 3p