Genomic and epidemiologic surveillance of SARS-CoV-2 in Southern Brazil and identification of a new Omicron-L452R sublineage

Authors: Mariana Soares da Silva, Juliana Schons Gularte, Micheli Filippi, Meriane Demoliner, Viviane Girardi, Ana Cristina Sbaraini Mosena, Vyctoria Malayhka de Abreu Góes Pereira, Alana Witt Hansen, Matheus Nunes Weber, Paula Rodrigues de Almeida, Juliane Deise Fleck, Andrea Gurgel Batista Leite Dal Bó, Marcus Herbert Jones, Frederico Friedrich, Luiz Amorim Filho, Fábio Klamt, Fernando Rosado Spilki

Source: Virus Research, Vol 321, Iss , Pp 198907- (2022)

Subject Terms: SARS-CoV-2, S:L452R, Mutational scanning, VOC, Microbiology, QR1-502, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0168170222002350; https://doaj.org/toc/1872-7492

Access URL: https://doaj.org/article/3bf036e81feb44b0a990f54d0ceb6728

Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

Authors: José Ignácio Gonzalez Solari, Eduardo Filippi-Chiela, Emily Salles Pilar, Vitória Nunes, Esteban Alberto Gonzalez, Fabrício Figueiró, Cristiano Feijó Andrade, Fábio Klamt

Source: BMC Cancer, Vol 20, Iss 1, Pp 1-14 (2020)

Subject Terms: Non-small cell lung carcinoma (NSCLC), Damage-associated molecular patterns (DAMPs), Immunogenic cell death (ICD), Autophagy, Cisplatin, Etoposide, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-020-06964-5; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/61d0021fae444f61bc9d2c933a67480d

Integrated transcriptomics reveals master regulators of lung adenocarcinoma and novel repositioning of drug candidates

Authors: Marco Antônio De Bastiani, Fábio Klamt

Source: Cancer Medicine, Vol 8, Iss 15, Pp 6717-6729 (2019)

Subject Terms: computational drug repositioning, connectivity map, lung cancer, master regulator, transcriptomic, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/71fd1fa5f8f94584af865b13afafcd88

EGR3 Immediate Early Gene and the Brain-Derived Neurotrophic Factor in Bipolar Disorder

Authors: Bianca Pfaffenseller, Flavio Kapczinski, Amelia L. Gallitano, Fábio Klamt

Source: Frontiers in Behavioral Neuroscience, Vol 12 (2018)

Subject Terms: immediate early genes, early growth response gene 3 (EGR3), brain-derived neurotrophic factor (BDNF), bipolar disorder, neuroplasticity, regulatory network, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://journal.frontiersin.org/article/10.3389/fnbeh.2018.00015/full; https://doaj.org/toc/1662-5153

Access URL: https://doaj.org/article/19837d5fbe1c4ca48c889318483783a4

Increased oxidative damage in carriers of the germline TP53 p.R337H mutation.

Authors: Gabriel S Macedo, Leonardo Lisbôa da Motta, Juliana Giacomazzi, Cristina B O Netto, Vanusa Manfredini, Camila S Vanzin, Carmen Regla Vargas, Pierre Hainaut, Fábio Klamt, Patricia Ashton-Prolla

Source: PLoS ONE, Vol 7, Iss 10, p e47010 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3467233?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/2bd510bbc68a40c0a63d3e448cb1aeba

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Can electrons travel through actin microfilaments and generate oxidative stress in retinol treated Sertoli cell?

Authors: Ramatis de Oliveira, Matheus de Bittencourt Pasquali, Alfeu Filho, Rodrigo Dalmolin, Daniel Gelain, Carmem Gottfried, José Rodrigues, Fábio Klamt, José Moreira

Source: Molecular & Cellular Biochemistry; Jul2007, Vol. 301 Issue 1/2, p33-45, 13p

Morphological and oxidative alterations on Sertoli cells cytoskeleton due to retinol-induced reactive oxygen species.

Authors: Ramatis Birnfeld de Oliveira, Fábio Klamt, Mauro A. A. Castro, Manuela Polydoro, Alfeu Zanotto Filho, Daniel Pens Gelain, Felipe Dal-Pizzol1, José Cláudio Fonseca Moreira1

Source: Molecular & Cellular Biochemistry; Mar2005, Vol. 271 Issue 1/2, p189-196, 8p

Enhanced UV-mediated free radical generation; DNA and mitochondrial damage caused by retinol supplementation.

Authors: Fábio Klamt, Felipe Dal-Pizzol, Elena Aida Bernard, José Cláudio Fonseca Moreira

Source: Photochemical & Photobiological Sciences; Aug2003, Vol. 2 Issue 8, p856-860, 5p

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Master Regulators Connectivity Map: A Transcription Factors-Centered Approach to Drug Repositioning

Authors: Marco A. De Bastiani, Bianca Pfaffenseller, Fabio Klamt

Source: Frontiers in Pharmacology, Vol 9 (2018)

Subject Terms: connectivity map, computational drug repositioning, master regulators, transcription factors, reverse engineering, systems pharmacology, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2018.00697/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/6f2018cec66c4b1ebba09acba6875dd9

Modulation of oxidative stress in response to gamma-radiation in human glioma cell lines.

Authors: Felipe Dal-Pizzol, Cristiane Ritter, Fábio Klamt, Michael Andrades

Source: Journal of Neuro-Oncology; May2003, Vol. 62 Issue 3, p361-361, 1p