LSD1+8a is an RNA biomarker of neuroendocrine prostate cancer

Authors: Anbarasu Kumaraswamy, Rahul Mannan, Olivia A. Swaim, Eva Rodansky, Xiao-Ming Wang, Aaron Udager, Rohit Mehra, Hui Li, Colm Morrissey, Eva Corey, Michael C. Haffner, Peter S. Nelson, Arul M. Chinnaiyan, Joel A. Yates, Joshi J. Alumkal

Source: Neoplasia: An International Journal for Oncology Research, Vol 63, Iss , Pp 101151- (2025)

Subject Terms: LSD1+8a, Neuroendocrine Prostate Cancer, RNA Biomarker, RNA In Situ Hybridization, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558625000302; https://doaj.org/toc/1476-5586

Access URL: https://doaj.org/article/c24d23de653d41fb920eb52783bf74be

Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity

Authors: Thomas C. Westbrook, Xiangnan Guan, Eva Rodansky, Diana Flores, Chia Jen Liu, Aaron M. Udager, Radhika A. Patel, Michael C. Haffner, Ya-Mei Hu, Duanchen Sun, Tomasz M. Beer, Adam Foye, Rahul Aggarwal, David A. Quigley, Jack F. Youngren, Charles J. Ryan, Martin Gleave, Yuzhuo Wang, Jiaoti Huang, Ilsa Coleman, Colm Morrissey, Peter S. Nelson, Christopher P. Evans, Primo Lara, Robert E. Reiter, Owen Witte, Matthew Rettig, Christopher K. Wong, Alana S. Weinstein, Vlado Uzunangelov, Josh M. Stuart, George V. Thomas, Felix Y. Feng, Eric J. Small, Joel A. Yates, Zheng Xia, Joshi J. Alumkal

Source: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/84a852fcb0624999ab330bdca23f4d3f

LSD1 promotes prostate cancer reprogramming by repressing TP53 signaling independently of its demethylase function

Authors: Anbarasu Kumaraswamy, Zhi Duan, Diana Flores, Chao Zhang, Archana Sehrawat, Ya-Mei Hu, Olivia A. Swaim, Eva Rodansky, William K. Storck, Joshua A. Kuleape, Karan Bedi, Rahul Mannan, Xiao-Ming Wang, Aaron Udager, Visweswaran Ravikumar, Armand Bankhead III, Ilsa Coleman, John K. Lee, Colm Morrissey, Peter S. Nelson, Arul M. Chinnaiyan, Arvind Rao, Zheng Xia, Joel A. Yates, Joshi J. Alumkal

Source: JCI Insight, Vol 8, Iss 15 (2023)

Subject Terms: Oncology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/e4a07a2910524a9eab732b3ab8ace38b