The Czech National MS Registry (ReMuS): Data trends in multiple sclerosis patients whose first disease-modifying therapies were initiated from 2013 to 2021

Authors: Dominika Stastna, Jiri Drahota, Michal Lauer, Aneta Mazouchova, Ingrid Menkyova, Jana Adamkova, Radek Ampapa, Michal Dufek, Marketa Grunermelova, Pavel Hradilek, Eva Kubala Havrdova, Jan Mares, Alena Martinkova, Zbysek Pavelek, Marek Peterka, Eva Recmanova, Petra Rockova, Ivana Stetkarova, Pavel Stourac, Marta Vachova, Dana Horakova

Source: Biomedical Papers, Vol 168, Iss 3, Pp 262-270 (2024)

Subject Terms: multiple sclerosis, disease-modifying therapy, high-efficacy therapy, platform therapy, treatment initiation, real-world data, registry, epidemiology, Medicine

File Description: electronic resource

Relation: https://biomed.papers.upol.cz/artkey/bio-202403-0011_the-czech-national-ms-registry-remus-data-trends-in-multiple-sclerosis-patients-whose-first-disease-modifyin.php; https://doaj.org/toc/1213-8118; https://doaj.org/toc/1804-7521

Access URL: https://doaj.org/article/031942c91d96488a818590beaafcebd7

Lysate of Parabacteroides distasonis prevents severe forms of experimental autoimmune encephalomyelitis by modulating the priming of T cell response

Authors: Zuzana Jiraskova Zakostelska, Michal Kraus, Stepan Coufal, Petra Prochazkova, Zaneta Slavickova, Tomas Thon, Tomas Hrncir, Jakub Kreisinger, Klara Kostovcikova, Pavlina Kleinova, Jana Lizrova Preiningerova, Miluse Pavelcova, Veronika Ticha, Ivana Kovarova, Eva Kubala Havrdova, Helena Tlaskalova-Hogenova, Miloslav Kverka

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: multiple sclerosis, experimental autoimmune encephalomyelitis, inflammation, Parabacteroides distasonis, microbiota, regulatory T cells, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1475126/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/97ff8d58fcf64dfeb21157fb3d391849

Real-world effectiveness of cladribine as an escalation strategy for MS: Insights from the Czech nationwide ReMuS registry

Authors: Pavel Potuznik, Jiri Drahota, Dana Horakova, Marek Peterka, Aneta Mazouchova, David Matyas, Zbysek Pavelek, Marta Vachova, Eva Recmanova, Ivana Stetkarova, Jana Libertinova, Jan Mares, Pavel Stourac, Marketa Grunermelova, Alena Martinkova, Jana Adamkova, Pavel Hradilek, Radek Ampapa, Michal Dufek, Eva Kubala Havrdova, Dominika Stastna

Source: Journal of Central Nervous System Disease, Vol 16 (2024)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1179-5735

Access URL: https://doaj.org/article/184f4c6999bb4bada8b072f3e0cb99d2

Long-term clinical outcomes in patients with multiple sclerosis who are initiating disease-modifying therapy with natalizumab compared with BRACETD first-line therapies

Authors: Helmut Butzkueven, Tomas Kalincik, Francesco Patti, Mark Slee, Bianca Weinstock-Guttman, Katherine Buzzard, Olga Skibina, Raed Alroughani, Alexandre Prat, Marc Girard, Dana Horakova, Eva Kubala Havrdova, Anneke Van der Walt, Sara Eichau, Robert Hyde, Nolan Campbell, Karthik Bodhinathan, Tim Spelman

Source: Therapeutic Advances in Neurological Disorders, Vol 17 (2024)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1756-2864

Access URL: https://doaj.org/article/5f44ff79362846b78e7b847750fa6b7f

Natalizumab promotes anti-inflammatory and repair effects in multiple sclerosis.

Authors: Ragnhild Reehorst Lereim, Petra Nytrova, Astrid Guldbrandsen, Eva Kubala Havrdova, Kjell-Morten Myhr, Harald Barsnes, Frode S Berven

Source: PLoS ONE, Vol 19, Iss 3, p e0300914 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0300914&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6f42bd6b46a240189c2680da823bc02c

Brainstem lesions are associated with diffuse spinal cord involvement in early multiple sclerosis

Authors: Michaela Andelova, Karolina Vodehnalova, Jan Krasensky, Eliska Hardubejova, Tereza Hrnciarova, Barbora Srpova, Tomas Uher, Ingrid Menkyova, Dominika Stastna, Lucie Friedova, Jiri Motyl, Jana Lizrova Preiningerova, Eva Kubala Havrdova, Bénédicte Maréchal, Mário João Fartaria, Tobias Kober, Dana Horakova, Manuela Vaneckova

Source: BMC Neurology, Vol 22, Iss 1, Pp 1-11 (2022)

Subject Terms: Multiple sclerosis, Infratentorial lesions, Spinal cord, Focal and diffuse lesions, thalamus, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2377

Access URL: https://doaj.org/article/4e0b4523cfb94fc49b3da5a0513014e1

Quality of Life Improves with Alemtuzumab Over 6 Years in Relapsing-Remitting Multiple Sclerosis Patients with or without Autoimmune Thyroid Adverse Events: Post Hoc Analysis of the CARE-MS Studies

Authors: Antonio Bertolotto, Rafael Arroyo, Elisabeth G. Celius, Giancarlo Comi, Eva Kubala Havrdova, William David Honeycutt, Samuel F. Hunter, Guillermo Izquierdo, Barbara Kornek, Tamara Miller, Dimos D. Mitsikostas, Barry A. Singer, Tjalf Ziemssen, Luke Chung, Nadia Daizadeh, Salman Afsar, Lobat Hashemi, Peter Senior

Source: Neurology and Therapy, Vol 9, Iss 2, Pp 443-457 (2020)

Subject Terms: Alemtuzumab, Health-related quality of life, Thyroid adverse events, Relapsing-remitting multiple sclerosis, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2193-8253; https://doaj.org/toc/2193-6536

Access URL: https://doaj.org/article/3bcc37fc46e84de69be4eb2c49df7148

Steroid Sulfation in Neurodegenerative Diseases

Authors: Jana Vitku, Martin Hill, Lucie Kolatorova, Eva Kubala Havrdova, Radmila Kancheva

Source: Frontiers in Molecular Biosciences, Vol 9 (2022)

Subject Terms: steroid sulfotransferases, steroid sulfatase, neuroactive steroids, neurosteroids, brain, Alzheimer’s disease, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2022.839887/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/8d29f4fae5f44884826e5fc1cf9cd5f1

Periventricular gradient of T1 tissue alterations in multiple sclerosis

Authors: Manuela Vaneckova, Gian Franco Piredda, Michaela Andelova, Jan Krasensky, Tomas Uher, Barbora Srpova, Eva Kubala Havrdova, Karolina Vodehnalova, Dana Horakova, Tom Hilbert, Bénédicte Maréchal, Mário João Fartaria, Veronica Ravano, Tobias Kober

Source: NeuroImage: Clinical, Vol 34, Iss , Pp 103009- (2022)

Subject Terms: Multiple sclerosis, Gradient of tissue damage, T1-relaxometry, MP2RAGE, Atlas-based assessment, Computer applications to medicine. Medical informatics, R858-859.7, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213158222000742; https://doaj.org/toc/2213-1582

Access URL: https://doaj.org/article/1506ff374cea4f969247281418142c5b

Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium.

Authors: Signe Hässler, Delphine Bachelet, Julianne Duhaze, Natacha Szely, Aude Gleizes, Salima Hacein-Bey Abina, Orhan Aktas, Michael Auer, Jerôme Avouac, Mary Birchler, Yoram Bouhnik, Olivier Brocq, Dorothea Buck-Martin, Guillaume Cadiot, Franck Carbonnel, Yehuda Chowers, Manuel Comabella, Tobias Derfuss, Niek De Vries, Naoimh Donnellan, Abiba Doukani, Michael Guger, Hans-Peter Hartung, Eva Kubala Havrdova, Bernhard Hemmer, Tom Huizinga, Kathleen Ingenhoven, Poul Erik Hyldgaard-Jensen, Elizabeth C Jury, Michael Khalil, Bernd Kieseier, Anna Laurén, Raija Lindberg, Amy Loercher, Enrico Maggi, Jessica Manson, Claudia Mauri, Badreddine Mohand Oumoussa, Xavier Montalban, Maria Nachury, Petra Nytrova, Christophe Richez, Malin Ryner, Finn Sellebjerg, Claudia Sievers, Dan Sikkema, Martin Soubrier, Sophie Tourdot, Caroline Trang, Alessandra Vultaggio, Clemens Warnke, Sebastian Spindeldreher, Pierre Dönnes, Timothy P Hickling, Agnès Hincelin Mery, Matthieu Allez, Florian Deisenhammer, Anna Fogdell-Hahn, Xavier Mariette, Marc Pallardy, Philippe Broët, ABIRISK consortium

Source: PLoS Medicine, Vol 17, Iss 10, p e1003348 (2020)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/4a837373673e4bce970064eeadc29077

Using Serum Metabolomics to Predict Development of Anti-drug Antibodies in Multiple Sclerosis Patients Treated With IFNβ

Authors: Kirsty E. Waddington, Artemis Papadaki, Leda Coelewij, Marsilio Adriani, Petra Nytrova, Eva Kubala Havrdova, Anna Fogdell-Hahn, Rachel Farrell, Pierre Dönnes, Inés Pineda-Torra, Elizabeth C. Jury

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: immunogenicity, anti-drug antibodies, multiple sclerosis, metabolomics, cholesterol, machine learning, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.01527/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3f18697f0ea04704bfe363826743d56e

Multiple Sclerosis and Microbiome

Authors: Jana Lizrova Preiningerova, Zuzana Jiraskova Zakostelska, Adhish Srinivasan, Veronika Ticha, Ivana Kovarova, Pavlina Kleinova, Helena Tlaskalova-Hogenova, Eva Kubala Havrdova

Source: Biomolecules, Vol 12, Iss 3, p 433 (2022)

Subject Terms: multiple sclerosis, microbiome, gut-brain axis, disease-modifying drugs, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/12/3/433; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/57674fe666c54524b2ec712b2ae023e6

Establishing pathological cut-offs for lateral ventricular volume expansion rates

Authors: Michael G. Dwyer, Jesper Hagemeier, Niels Bergsland, Dana Horakova, Jonathan R. Korn, Nasreen Khan, Tomas Uher, Jennie Medin, Diego Silva, Manuela Vaneckova, Eva Kubala Havrdova, Robert Zivadinov

Source: NeuroImage: Clinical, Vol 18, Iss , Pp 494-501 (2018)

Subject Terms: Computer applications to medicine. Medical informatics, R858-859.7, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213158218300433; https://doaj.org/toc/2213-1582

Access URL: https://doaj.org/article/043a9280fcbf40a292d1e4263123cb93

Natalizumab Induces Changes of Cerebrospinal Fluid Measures in Multiple Sclerosis

Authors: Ranjani Ganapathy Subramanian, Dana Horakova, Manuela Vaneckova, Balazs Lorincz, Jan Krasensky, Eva Kubala Havrdova, Tomas Uher

Source: Diagnostics, Vol 11, Iss 12, p 2230 (2021)

Subject Terms: natalizumab, cerebrospinal fluid, brain atrophy, oligoclonal bands, MRI, multiple sclerosis, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/11/12/2230; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/0526435ba0ed4afe999b8e05c9d85b05

Additive Effect of Spinal Cord Volume, Diffuse and Focal Cord Pathology on Disability in Multiple Sclerosis

Authors: Michaela Andelova, Tomas Uher, Jan Krasensky, Lukas Sobisek, Eliska Kusova, Barbora Srpova, Karolina Vodehnalova, Lucie Friedova, Jiri Motyl, Jana Lizrova Preiningerova, Eva Kubala Havrdova, Dana Horakova, Manuela Vaneckova

Source: Frontiers in Neurology, Vol 10 (2019)

Subject Terms: magnetic resonance imaging, spinal cord, focal lesions, diffuse abnormalities, spinal cord reserve, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fneur.2019.00820/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/a08176d0fcd54ea38509e2921d17a698

Isolated Cognitive Decline in Neurologically Stable Patients with Multiple Sclerosis

Authors: Jiri Motyl, Lucie Friedova, Manuela Vaneckova, Jan Krasensky, Balazs Lorincz, Jana Blahova Dusankova, Michaela Andelova, Tom A. Fuchs, Eva Kubala Havrdova, Ralph H. B. Benedict, Dana Horakova, Tomas Uher

Source: Diagnostics, Vol 11, Iss 3, p 464 (2021)

Subject Terms: cognitive decline, isolated cognitive decline, cognition, disease activity monitoring, relapse, disability, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/11/3/464; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/adb5c71deca349d59a934d3bc82f014e

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Efficacy and safety of alemtuzumab over 6 years: final results of the 4-year CARE-MS extension trial

Authors: Alasdair J. Coles, Douglas L. Arnold, Ann D. Bass, Aaron L. Boster, D. Alastair S. Compston, Óscar Fernández, Eva Kubala Havrdová, Kunio Nakamura, Anthony Traboulsee, Tjalf Ziemssen, Alan Jacobs, David H. Margolin, Xiaobi Huang, Nadia Daizadeh, Madalina C. Chirieac, Krzysztof W. Selmaj

Source: Therapeutic Advances in Neurological Disorders, Vol 14 (2021)

Subject Terms: Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1756-2864

Access URL: https://doaj.org/article/0fa2ae77784345bda11b4afff0c00fe1