Isoxazole-based molecules restore NK cell immune surveillance in hepatocarcinogenesis by targeting TM4SF5 and SLAMF7 linkage

Authors: Ji Eon Kim, Hyun Su Kim, Wonsik Kim, Eun Hae Lee, Soyeon Kim, Taewoo Kim, Eun-Ae Shin, Kyung-hee Pyo, Haesong Lee, Seo Hee Jin, Jae-Ho Lee, Soo-Min Byeon, Dong Joo Kim, Jinwook Jeong, Jeongwon Lee, Minjae Ohn, Hyojung Lee, Su Jong Yu, Dongyun Shin, Semi Kim, Jun Yeob Yoo, Seung-Chul Lee, Young-Ger Suh, Jung Weon Lee

Source: Signal Transduction and Targeted Therapy, Vol 10, Iss 1, Pp 1-18 (2025)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/addb895ff9814918984b6f498b379722

Glucose‐mediated mitochondrial reprogramming by cholesterol export at TM4SF5‐enriched mitochondria‐lysosome contact sites

Authors: Ji Eon Kim, So‐Young Park, Chulhwan Kwak, Yoonji Lee, Dae‐Geun Song, Jae Woo Jung, Haesong Lee, Eun‐Ae Shin, Yangie Pinanga, Kyung‐hee Pyo, Eun Hae Lee, Wonsik Kim, Soyeon Kim, Chang‐Duck Jun, Jeanho Yun, Sun Choi, Hyun‐Woo Rhee, Kwang‐Hyeon Liu, Jung Weon Lee

Source: Cancer Communications, Vol 44, Iss 1, Pp 47-75 (2024)

Subject Terms: cholesterol, fluorescent imaging, glucose catabolism, hepatocellular carcinogenesis, membrane contact sites, mitochondria function, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2523-3548

Access URL: https://doaj.org/article/46fc9bb08a664adcac5b903aa7d00a58

TM4SF5-mediated abnormal food-intake behavior and apelin expression facilitate non-alcoholic fatty liver disease features

Authors: Yangie Dwi Pinanga, Han Ah Lee, Eun-Ae Shin, Haesong Lee, Kyung-hee Pyo, Ji Eon Kim, Eun Hae Lee, Wonsik Kim, Soyeon Kim, Hwi Young Kim, Jung Weon Lee

Source: iScience, Vol 26, Iss 9, Pp 107625- (2023)

Subject Terms: Biological sciences, Cell biology, Molecular biology, Physiology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223017029; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/b5ded654f1644a37a4b5f1cff57abe43

Therapeutic effects of TM4SF5-targeting chimeric and humanized monoclonal antibodies in hepatocellular and colon cancer models

Authors: Dongjoon Ko, Eunmi Kim, Eun-Ae Shin, Seo Hee Nam, Junghwa Yoon, Jin-Sook Lee, Yunhee Lee, Sora Park, Kyungsoo Ha, So-Young Choi, Jung Weon Lee, Semi Kim

Source: Molecular Therapy: Oncolytics, Vol 24, Iss , Pp 452-466 (2022)

Subject Terms: TM4SF5, antibody, therapeutics, liver cancer, colon cancer, humanization, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770522000109; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/6a71f920fd7c41e5801990df6d3021f2

Liver‐originated small extracellular vesicles with TM4SF5 target brown adipose tissue for homeostatic glucose clearance

Authors: Jae Woo Jung, Ji Eon Kim, Eunmi Kim, Hyejin Lee, Haesong Lee, Eun‐Ae Shin, Jung Weon Lee

Source: Journal of Extracellular Vesicles, Vol 11, Iss 9, Pp n/a-n/a (2022)

Subject Terms: brown adipose tissue, glucose transporter, hepatic sEVs, protein–protein interaction, tetraspanin, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2001-3078

Access URL: https://doaj.org/article/c6bea7b250484a6a8bd103962779a5ea

Crosstalk between TM4SF5 and GLUT8 regulates fructose metabolism in hepatic steatosis

Authors: Hyejin Lee, Eunmi Kim, Eun-Ae Shin, Jong Cheol Shon, Hyunseung Sun, Ji Eon Kim, Jae Woo Jung, Haesong Lee, Yangie Pinanga, Dae-Geun Song, Kwang-Hyeon Liu, Jung Weon Lee

Source: Molecular Metabolism, Vol 58, Iss , Pp 101451- (2022)

Subject Terms: Fructose metabolism, Steatosis, Triacylglycerol, GLUT8, Tetraspanin, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877822000205; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/d0ea7ae201134157a2dc84c96ee86c4f

TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment

Authors: Eunmi Kim, Hyejin Um, Jinsoo Park, Jae Woo Jung, Ji Eon Kim, Haesong Lee, Eun-Ae Shin, Yangie Pinanga, Hyejin Lee, Seo Hee Nam, Jung Weon Lee

Source: Cell Reports, Vol 37, Iss 7, Pp 110018- (2021)

Subject Terms: cytokines/chemokines, diet animal model, fibrosis, glycolysis, hepatocytes, inflammation, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S221112472101500X; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/30bc3a81cc954bfe861f776a7c275d30

Exploring vitamin D metabolism and function in cancer

Authors: Sang-Min Jeon, Eun-Ae Shin

Source: Experimental and Molecular Medicine, Vol 50, Iss 4, Pp 1-14 (2018)

Subject Terms: Medicine, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2092-6413

Access URL: https://doaj.org/article/cb271445325747139010a0ecc37ba602