German Medical Informatics Initiative: Unlocking Data for Research and Health Care

Authors: Gehring, Stefanie, Eulenfeld, René

Source: Methods of information in medicine. 57:e46-e49

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185583317.0x000001&indx=1&recIds=ETOCvdc_100185583317.0x000001

MAPK-induced Gab1 translocation to the plasma membrane depends on a regulated intramolecular switch

Authors: Wolf, Alexandra, Eulenfeld, René, Bongartz, Hannes, Hessenkemper, Wiebke, Simister, Philip C., Lievens, Sam, Tavernier, Jan, Feller, Stephan M., Schaper, Fred

Source: In Cellular Signalling February 2015 27(2):340-352

Interleukin-6 signalling: More than Jaks and STATs

Authors: Eulenfeld, René, Dittrich, Anna, Khouri, Christina, Müller, Pia J., Mütze, Barbara, Wolf, Alexandra, Schaper, Fred

Source: In European Journal of Cell Biology June-July 2012 91(6-7):486-495

The oncogenic FIP1L1-PDGFRα fusion protein displays skewed signaling properties compared to its wild-type PDGFRα counterpart

Authors: Haan, Serge, Bahlawane, Christelle, Wang, Jiali, Nazarov, Petr V, Muller, Arnaud, Eulenfeld, René, Haan, Claude, Rolvering, Catherine, Vallar, Laurent, Satagopam, Venkata P, Sauter, Thomas, Wiesinger, Monique Yvonne

Source: JAK-STAT. 4(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100051740781.0x000001&indx=1&recIds=ETOCvdc_100051740781.0x000001

Constitutive activation of oncogenic PDGFRα-mutant proteins occurring in GIST patients induces receptor mislocalisation and alters PDGFRa signalling characteristics.

Authors: Bahlawane, Christelle¹, Eulenfeld, René², Wiesinger, Monique Y.³, Jiali Wang¹, Muller, Arnaud⁴, Girod, Andreas⁵, Nazarov, Petr V.⁴, Felsch, Kathrin⁶, Vallar, Laurent⁴, Sauter, Thomas³, Satagopam, Venkata P.⁷, Haan, Serge^1,2,6 serge.haan@uni.lu

Source: Cell Communication & Signaling. 2015, Vol. 13 Issue 1, p1-21. 21p.

Subject Terms: *ONCOGENIC proteins, *GASTROINTESTINAL stromal tumors, *PROTEIN-tyrosine kinases, *EPIDERMAL growth factor receptors, *ENDOPLASMIC reticulum

JAK2-V617F-induced MAPK activity is regulated by PI3K and acts synergistically with PI3K on the proliferation of JAK2-V617F-positive cells

Authors: Wolf, Alexandra, Eulenfeld, René, Gäbler, Karoline, Rolvering, Catherine, Haan, Serge, Behrmann, Iris, Denecke, Bernd, Haan, Claude, Schaper, Fred

Source: JAK-STAT. 2(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100051739435.0x000001&indx=1&recIds=ETOCvdc_100051739435.0x000001

ID: 58

Authors: Hessenkemper, Wiebke, Bongartz, Hannes, Fritsch, Johannes, Wolf, Alexandra, Eulenfeld, René, Simister, Philip C., Feller, Stephan M., Schaper, Fred

Source: Cytokine. 76(1):75-75

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100029286676.0x000001&indx=1&recIds=ETOCvdc_100029286676.0x000001

ID: 79

Authors: Bongartz, Hannes, Hessenkemper, Wiebke, Wolf, Alexandra, Eulenfeld, René, Simister, Philip C., Behrmann, Iris, Tavernier, Jan, Feller, Stephan M., Haan, Claude, Schaper, Fred

Source: Cytokine. 76(1):80-80

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100029272101.0x000001&indx=1&recIds=ETOCvdc_100029272101.0x000001

ID: 79: Constitutive membrane binding of the multi-site docking protein Gab1 in JAK2-V617F expressing cells

Authors: Bongartz, Hannes, Hessenkemper, Wiebke, Wolf, Alexandra, Eulenfeld, René, Simister, Philip C., Behrmann, Iris, Tavernier, Jan, Feller, Stephan M., Haan, Claude, Schaper, Fred

Source: In Cytokine November 2015 76(1):80-80

ID: 58: Involvement of MAPK- and PI3K-pathway in Gab1 translocation and phosphorylation

Authors: Hessenkemper, Wiebke, Bongartz, Hannes, Fritsch, Johannes, Wolf, Alexandra, Eulenfeld, René, Simister, Philip C., Feller, Stephan M., Schaper, Fred

Source: In Cytokine November 2015 76(1):75-75

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Cooperative effects of Janus and Aurora kinase inhibition by CEP701 in cells expressing Jak2V617F.

Authors: Gäbler, Karoline, Rolvering, Catherine, Kaczor, Jakub, Eulenfeld, René, Méndez, Sergio Álvarez, Berchem, Guy, Palissot, Valérie, Behrmann, Iris, Haan, Claude

Source: Journal of Cellular & Molecular Medicine; Feb2013, Vol. 17 Issue 2, p265-276, 12p, 1 Chart, 5 Graphs

Subject Terms: AURORA kinases, GENE expression, MYELOPROLIFERATIVE neoplasms, IMMUNE response, KINASE inhibitors, GENETIC mutation, CANCER cells

Interleukin-6 induces translocation of the adapter protein GAB1 by MAPK-dependent phosphorylation of GAB1 on serine 552

Authors: Wolf, Alexandra, Eulenfeld, René, Feller, Stephan M., Schaper, Fred

Source: In Cytokine October-November 2009 48(1-2):37-37

359 A novel mechanism for the regulation of GAB1 recruitment to the plasma membrane

Authors: Eulenfeld, René, Schaper, Fred

Source: In Cytokine September 2008 43(3):328-329

˜Dasœ Adapterprotein Gab1 in der Regulation der IL-6 Signaltransduktion

Contributors: Eulenfeld, René

Availability: http://data.europeana.eu/aggregation/europeana/2048441/item_SEHOQ4L7BTLVJFX4TAFZ6YTTZOZWT6OX

The oncogenic FIP1L1-PDGFR α fusion protein displays skewed signaling properties compared to its wild-type PDGFR α counterpart.

Authors: Haan, Serge, Bahlawane, Christelle, Jiali Wang, Nazarov, Petr V., Muller, Arnaud, Eulenfeld, René, Haan, Claude, Rolvering, Catherine, Vallar, Laurent, Satagopam, Venkata P., Sauter, Thomas, Wiesinger, Monique Yvonne

Source: JAK-STAT; 2015, Vol. 4 Issue 1, pN.PAG-N.PAG, 0p, 1 Color Photograph, 4 Black and White Photographs, 2 Diagrams, 2 Graphs

Subject Terms: ONCOGENIC proteins, CHIMERIC proteins, PLATELET-derived growth factor receptors, STAT proteins, CELLULAR signal transduction, MITOGEN-activated protein kinases, JANUS kinases