Inflammatory signature in amyotrophic lateral sclerosis predicting disease progression

Authors: Cinzia Femiano, Antonio Bruno, Luana Gilio, Fabio Buttari, Ettore Dolcetti, Giovanni Galifi, Federica Azzolini, Angela Borrelli, Roberto Furlan, Annamaria Finardi, Alessandra Musella, Georgia Mandolesi, Marianna Storto, Diego Centonze, Mario Stampanoni Bassi

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Amyotrophic lateral sclerosis (ALS), Neuroinflammation, Disease progression, Cerebrospinal fluid (CSF), Cytokines, Neutrophil-to-lymphocytes ratio (NLR), Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/1f57bd670cb64b908210235a78a09890

Interleukin-9 protects from microglia- and TNF-mediated synaptotoxicity in experimental multiple sclerosis

Authors: Livia Guadalupi, Valentina Vanni, Sara Balletta, Silvia Caioli, Francesca De Vito, Diego Fresegna, Krizia Sanna, Monica Nencini, Gloria Donninelli, Elisabetta Volpe, Fabrizio Mariani, Luca Battistini, Mario Stampanoni Bassi, Luana Gilio, Antonio Bruno, Ettore Dolcetti, Fabio Buttari, Georgia Mandolesi, Diego Centonze, Alessandra Musella

Source: Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)

Subject Terms: Experimental multiple sclerosis, Neuroinflammation, Synaptopathy, Microglia activation, Inflammatory cytokines, Glutamate transmission, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1742-2094

Access URL: https://doaj.org/article/26b7e6dea36f445e8ff5a21fed98ca24

Interleukin-10 contrasts inflammatory synaptopathy and central neurodegenerative damage in multiple sclerosis

Authors: Luana Gilio, Diego Fresegna, Mario Stampanoni Bassi, Alessandra Musella, Francesca De Vito, Sara Balletta, Krizia Sanna, Silvia Caioli, Luigi Pavone, Giovanni Galifi, Ilaria Simonelli, Livia Guadalupi, Valentina Vanni, Fabio Buttari, Ettore Dolcetti, Antonio Bruno, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Annamaria Finardi, Roberto Furlan, Diego Centonze, Georgia Mandolesi

Source: Frontiers in Molecular Neuroscience, Vol 17 (2024)

Subject Terms: multiple sclerosis, interleukin-10, interleukin-1β, experimental autoimmune encephalomyelitis (EAE), GABA transmission, glutamate transmission, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2024.1430080/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/ed68c14e647544c18a236063464bd095

Physical exercise and synaptic protection in human and pre-clinical models of multiple sclerosis

Authors: Federica Azzolini, Ettore Dolcetti, Antonio Bruno, Valentina Rovella, Diego Centonze, Fabio Buttari

Source: Neural Regeneration Research, Vol 19, Iss 8, Pp 1768-1771 (2024)

Subject Terms: disease-modifying behaviour, endocannabinoid system, long-term potentiation, multiple sclerosis, neuroplasticity, neuroprotection, physical exercise, synaptopathy, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://www.nrronline.org/article.asp?issn=1673-5374;year=2024;volume=19;issue=8;spage=1768;epage=1771;aulast=; https://doaj.org/toc/1673-5374

Access URL: https://doaj.org/article/d8ba31cd8c6341baa52b495f4e689a94

Re-emergence of T lymphocyte-mediated synaptopathy in progressive multiple sclerosis

Authors: Krizia Sanna, Antonio Bruno, Sara Balletta, Silvia Caioli, Monica Nencini, Diego Fresegna, Livia Guadalupi, Ettore Dolcetti, Federica Azzolini, Fabio Buttari, Roberta Fantozzi, Angela Borrelli, Mario Stampanoni Bassi, Luana Gilio, Gianluca Lauritano, Valentina Vanni, Francesca De Vito, Alice Tartacca, Fabrizio Mariani, Valentina Rovella, Alessandra Musella, Diego Centonze, Georgia Mandolesi

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: secondary progressive multiple sclerosis, neurodegeneration, sphingosine receptor modulators, lymphocyte-mediated synaptopathy, neuroinflammation, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1416133/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/8487908276e1450781995b35527d24c5

Low-contrast visual acuity test is associated with central inflammation and predicts disability development in newly diagnosed multiple sclerosis patients

Authors: Ettore Dolcetti, Fabio Buttari, Antonio Bruno, Federica Azzolini, Luana Gilio, Veronica Di Caprio, Gianluca Lauritano, Angela Borrelli, Giovanni Galifi, Roberto Furlan, Annamaria Finardi, Alessandra Musella, Livia Guadalupi, Georgia Mandolesi, Valentina Rovella, Diego Centonze, Mario Stampanoni Bassi

Source: Frontiers in Neurology, Vol 15 (2024)

Subject Terms: LCVA, multiple sclerosis, IL-10, EDSS, MSSS, disability, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2024.1326506/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/36a2df04bbfa4ba8b990b495f611ada3

Tumor necrosis factor superfamily in multiple sclerosis: from pathology to therapeutic implications

Authors: Federica Azzolini, Antonio Bruno, Ettore Dolcetti, Diego Centonze, Fabio Buttari

Source: Bleeding, Thrombosis and Vascular Biology, Vol 2, Iss 2 (2023)

Subject Terms: TNF, multiple sclerosis, synaptopathy, TNFR1, TNFR2, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://btvb.org/btvb/article/view/66; https://doaj.org/toc/2785-5309

Access URL: https://doaj.org/article/4529d5522076494b877a235e7879a3f6

Preventive exercise attenuates IL-2-driven mood disorders in multiple sclerosis

Authors: Luana Gilio, Diego Fresegna, Antonietta Gentile, Livia Guadalupi, Krizia Sanna, Francesca De Vito, Sara Balletta, Silvia Caioli, Francesca Romana Rizzo, Alessandra Musella, Ennio Iezzi, Alessandro Moscatelli, Giovanni Galifi, Roberta Fantozzi, Paolo Bellantonio, Roberto Furlan, Annamaria Finardi, Valentina Vanni, Ettore Dolcetti, Antonio Bruno, Fabio Buttari, Georgia Mandolesi, Diego Centonze, Mario Stampanoni Bassi

Source: Neurobiology of Disease, Vol 172, Iss , Pp 105817- (2022)

Subject Terms: Multiple sclerosis, Exercise, Inflammation, Depression, Anxiety, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996122002091; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/ac52ca22b5d7497d80e10f72fbf424a7

Is transient ischemic attack a minor stroke?

Authors: Ettore Dolcetti, Antonio Bruno, Diego Centonze

Source: Bleeding, Thrombosis and Vascular Biology, Vol 1, Iss 1 (2022)

Subject Terms: TIA, Minor Stroke, Neurovascular Medicine, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://btvb.org/btvb/article/view/31; https://doaj.org/toc/2785-5309

Access URL: https://doaj.org/article/5156e88c181e41b89df370ec207e7901

Theoretical and Therapeutic Implications of the Spasticity-Plus Syndrome Model in Multiple Sclerosis

Authors: Antonio Bruno, Ettore Dolcetti, Diego Centonze

Source: Frontiers in Neurology, Vol 12 (2022)

Subject Terms: multiple sclerosis, spasticity, cannabinoid, symptoms therapy, axonal transmission, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fneur.2021.802918/full; https://doaj.org/toc/1664-2295

Access URL: https://doaj.org/article/ef24e9db80494ef3b6945b0f9ea7c2f3

Osteopontin Is Associated with Multiple Sclerosis Relapses

Authors: Mario Stampanoni Bassi, Fabio Buttari, Luana Gilio, Ennio Iezzi, Giovanni Galifi, Fortunata Carbone, Teresa Micillo, Ettore Dolcetti, Federica Azzolini, Antonio Bruno, Angela Borrelli, Georgia Mandolesi, Valentina Rovella, Marianna Storto, Annamaria Finardi, Roberto Furlan, Diego Centonze, Giuseppe Matarese

Source: Biomedicines, Vol 11, Iss 1, p 178 (2023)

Subject Terms: osteopontin, multiple sclerosis, cytokines, inflammation, IL-6, relapses, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/11/1/178; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/fe9e75357b304c719668b008e4ebe7e6

Fatigue in Multiple Sclerosis Is Associated with Reduced Expression of Interleukin-10 and Worse Prospective Disease Activity

Authors: Luana Gilio, Fabio Buttari, Luigi Pavone, Ennio Iezzi, Giovanni Galifi, Ettore Dolcetti, Federica Azzolini, Antonio Bruno, Angela Borrelli, Marianna Storto, Roberto Furlan, Annamaria Finardi, Tatjana Pekmezovic, Jelena Drulovic, Georgia Mandolesi, Diego Fresegna, Valentina Vanni, Diego Centonze, Mario Stampanoni Bassi

Source: Biomedicines, Vol 10, Iss 9, p 2058 (2022)

Subject Terms: relapsing-remitting multiple sclerosis (RR-MS), fatigue, inflammation, IL-10, NEDA-3, T2 lesion load, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/9/2058; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/4368af12dd0a45429e0b74433b908eef

Corrigendum: Inflammation-Associated Synaptic Alterations as Shared Threads in Depression and Multiple Sclerosis

Authors: Antonio Bruno, Ettore Dolcetti, Francesca Romana Rizzo, Diego Fresegna, Alessandra Musella, Antonietta Gentile, Francesca De Vito, Silvia Caioli, Livia Guadalupi, Silvia Bullitta, Valentina Vanni, Sara Balletta, Krizia Sanna, Fabio Buttari, Mario Stampanoni Bassi, Diego Centonze, Georgia Mandolesi

Source: Frontiers in Cellular Neuroscience, Vol 14 (2021)

Subject Terms: multiple sclerosis, major depressive disorder, excitotoxicity, antidepressant drugs, cytokines, synaptopathy, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fncel.2020.647259/full; https://doaj.org/toc/1662-5102

Access URL: https://doaj.org/article/af96bbb2ff274d0ebe8e742f1d6fe33c

Inflammation-Associated Synaptic Alterations as Shared Threads in Depression and Multiple Sclerosis

Authors: Antonio Bruno, Ettore Dolcetti, Francesca Romana Rizzo, Diego Fresegna, Alessandra Musella, Antonietta Gentile, Francesca De Vito, Silvia Caioli, Livia Guadalupi, Silvia Bullitta, Valentina Vanni, Sara Balletta, Krizia Sanna, Fabio Buttari, Mario Stampanoni Bassi, Diego Centonze, Georgia Mandolesi

Source: Frontiers in Cellular Neuroscience, Vol 14 (2020)

Subject Terms: multiple sclerosis, major depressive disorder, excitotoxicity, antidepressant drugs, cytokines, synaptopathy, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fncel.2020.00169/full; https://doaj.org/toc/1662-5102

Access URL: https://doaj.org/article/5c566a4156b3407b9f6e36f268aee17f

Neuroinflammation Is Associated with GFAP and sTREM2 Levels in Multiple Sclerosis

Authors: Federica Azzolini, Luana Gilio, Luigi Pavone, Ennio Iezzi, Ettore Dolcetti, Antonio Bruno, Fabio Buttari, Alessandra Musella, Georgia Mandolesi, Livia Guadalupi, Roberto Furlan, Annamaria Finardi, Teresa Micillo, Fortunata Carbone, Giuseppe Matarese, Diego Centonze, Mario Stampanoni Bassi

Source: Biomolecules, Vol 12, Iss 2, p 222 (2022)

Subject Terms: multiple sclerosis (MS), neuroinflammation, neurodegeneration, microglia, astroglia, soluble triggering receptor expressed on myeloid cells-2 (sTREM-2), Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/12/2/222; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/2db5546a609f491d87bf82b8ef3ce066

Interferon-γ causes mood abnormalities by altering cannabinoid CB1 receptor function in the mouse striatum

Authors: Georgia Mandolesi, Silvia Bullitta, Diego Fresegna, Antonietta Gentile, Francesca De Vito, Ettore Dolcetti, Francesca R. Rizzo, Georgios Strimpakos, Diego Centonze, Alessandra Musella

Source: Neurobiology of Disease, Vol 108, Iss , Pp 45-53 (2017)

Subject Terms: Type-1 cannabinoid receptor, Striatum, Interferon-gamma, Anxiety, Depression, Experimental autoimmune encephalomyelitis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996117301717; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/eea5db5be49a424cbb0e5ebca4067f93

The microRNA let-7b-5p Is Negatively Associated with Inflammation and Disease Severity in Multiple Sclerosis

Authors: Georgia Mandolesi, Francesca Romana Rizzo, Sara Balletta, Mario Stampanoni Bassi, Luana Gilio, Livia Guadalupi, Monica Nencini, Alessandro Moscatelli, Colleen Patricia Ryan, Valerio Licursi, Ettore Dolcetti, Alessandra Musella, Antonietta Gentile, Diego Fresegna, Silvia Bullitta, Silvia Caioli, Valentina Vanni, Krizia Sanna, Antonio Bruno, Fabio Buttari, Chiara Castelli, Carlo Presutti, Francesca De Santa, Annamaria Finardi, Roberto Furlan, Diego Centonze, Francesca De Vito

Source: Cells, Vol 10, Iss 2, p 330 (2021)

Subject Terms: multiple sclerosis (MS), miRNAs, let-7, inflammation, Expanded Disability Status Scale (EDSS), progressive multiple sclerosis (PMS), Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/10/2/330; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/e183758a0a9d4541b2246ceed96952d3

Re-Examining the Role of TNF in MS Pathogenesis and Therapy

Authors: Diego Fresegna, Silvia Bullitta, Alessandra Musella, Francesca Romana Rizzo, Francesca De Vito, Livia Guadalupi, Silvia Caioli, Sara Balletta, Krizia Sanna, Ettore Dolcetti, Valentina Vanni, Antonio Bruno, Fabio Buttari, Mario Stampanoni Bassi, Georgia Mandolesi, Diego Centonze, Antonietta Gentile

Source: Cells, Vol 9, Iss 10, p 2290 (2020)

Subject Terms: TNFR1, TNFR2, TNF therapy, demyelination, neurodegeneration, synaptic damage, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/10/2290; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/0156e49395714ee691c533cd27cc2129

Central Modulation of Selective Sphingosine-1-Phosphate Receptor 1 Ameliorates Experimental Multiple Sclerosis

Authors: Alessandra Musella, Antonietta Gentile, Livia Guadalupi, Francesca Romana Rizzo, Francesca De Vito, Diego Fresegna, Antonio Bruno, Ettore Dolcetti, Valentina Vanni, Laura Vitiello, Silvia Bullitta, Krizia Sanna, Silvia Caioli, Sara Balletta, Monica Nencini, Fabio Buttari, Mario Stampanoni Bassi, Diego Centonze, Georgia Mandolesi

Source: Cells, Vol 9, Iss 5, p 1290 (2020)

Subject Terms: sphingosine-1-phosphate receptors, glutamate synaptic dysfunction, microglia, T lymphocytes, experimental autoimmune encephalomyelitis (EAE), pro-inflammatory cytokines, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/5/1290; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/965eeda4259b4004a404f921313c17b7

Exploiting the Multifaceted Effects of Cannabinoids on Mood to Boost Their Therapeutic Use Against Anxiety and Depression

Authors: Mario Stampanoni Bassi, Luana Gilio, Pierpaolo Maffei, Ettore Dolcetti, Antonio Bruno, Fabio Buttari, Diego Centonze, Ennio Iezzi

Source: Frontiers in Molecular Neuroscience, Vol 11 (2018)

Subject Terms: endocannabinoids, reward, stress, depression, anxiety, multiple sclerosis, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fnmol.2018.00424/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/9b86939dab9544db82a5079d7cd14e02