Protection of stromal cell-derived factor-1 SDF-1/CXCL12 against proteases yields improved skin wound healing

Authors: Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Estefania Ugarte-Berzal, Jennifer Vandooren, Erik Martens, Mieke Gouwy, Eva Ganseman, Jo Van Damme, Patrick Matthys, Jan Jeroen Vranckx, Paul Proost, Ghislain Opdenakker

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: SDF-1, CXCL12, proteolysis, chemokine, COAM, wound healing, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1359497/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a3beb009fdca434c94d95233677ef312

Physiological fibrin hydrogel modulates immune cells and molecules and accelerates mouse skin wound healing

Authors: Rafaela Vaz Sousa Pereira, Mostafa EzEldeen, Estefania Ugarte-Berzal, Erik Martens, Bert Malengier-Devlies, Jennifer Vandooren, Jan Jeroen Vranckx, Patrick Matthys, Ghislain Opdenakker

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: wound healing, fibrin, leukocytes, macrophages, inflammation, hydrogel, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1170153/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9a6150249c7b408392914a097751c5d7

Proteoform Analysis of Matrix Metalloproteinase-9/Gelatinase B and Discovery of Its Citrullination in Rheumatoid Arthritis Synovial Fluids

Authors: Bernard Grillet, Karen Yu, Estefania Ugarte-Berzal, Rik Janssens, Rafaela Vaz Sousa Pereira, Lise Boon, Erik Martens, Nele Berghmans, Isabelle Ronsse, Ilse Van Aelst, Pierre Fiten, René Conings, Jennifer Vandooren, Patrick Verschueren, Jo Van Damme, Paul Proost, Ghislain Opdenakker

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: matrix metalloproteinase, arthritis, proteoform, proteolysis, citrullination, synovial fluid, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.763832/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/fcdb7e2221a94516bc4d928080b5e8a7

Internal Disulfide Bonding and Glycosylation of Interleukin-7 Protect Against Proteolytic Inactivation by Neutrophil Metalloproteinases and Serine Proteases

Authors: Jennifer Vandooren, Rafaela Vaz Sousa Pereira, Estefania Ugarte-Berzal, Vasily Rybakin, Sam Noppen, Melissa R. Stas, Eline Bernaerts, Eva Ganseman, Mieke Metzemaekers, Dominique Schols, Paul Proost, Ghislain Opdenakker

Source: Frontiers in Immunology, Vol 12 (2021)

Subject Terms: IL-7, matrix metalloproteinase-9, proteolysis, signal transduction, proliferation, neutrophils, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2021.701739/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/caa802cfe35d4da393ab5bd67065bfda

Bivalent Inhibitor with Selectivity for Trimeric MMP-9 Amplifies Neutrophil Chemotaxis and Enables Functional Studies on MMP-9 Proteoforms

Authors: Elisa Nuti, Armando Rossello, Doretta Cuffaro, Caterina Camodeca, Jens Van Bael, Dries van der Maat, Erik Martens, Pierre Fiten, Rafaela Vaz Sousa Pereira, Estefania Ugarte-Berzal, Mieke Gouwy, Ghislain Opdenakker, Jennifer Vandooren

Source: Cells, Vol 9, Iss 7, p 1634 (2020)

Subject Terms: MMP-9, inflammation, endotoxemia, leukocytosis, chemotaxis, sepsis, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/9/7/1634; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/598faee1983745e0a58f6bed59c8b4c2

MMP-9/Gelatinase B Degrades Immune Complexes in Systemic Lupus Erythematosus

Authors: Estefania Ugarte-Berzal, Lise Boon, Erik Martens, Vasily Rybakin, Daniel Blockmans, Jennifer Vandooren, Paul Proost, Ghislain Opdenakker

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: matrix metalloproteinase-9, immune complexes, immunoglobulins, systemic lupus erythematosus, drug-induced lupus erythematosus, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00538/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a4b9062768884583a438c8f22cad5c83

Recombinant Protein-Based Nanoparticles: Elucidating Their Inflammatory Effects In Vivo and Their Potential as a New Therapeutic Format

Authors: Laia Gifre-Renom, Estefania Ugarte-Berzal, Erik Martens, Lise Boon, Olivia Cano-Garrido, Esther Martínez-Núñez, Teresa Luque, Ramon Roca-Pinilla, Òscar Conchillo-Solé, Neus Ferrer-Miralles, Antonio Villaverde, Ghislain Opdenakker, Elena Garcia-Fruitós, Anna Arís

Source: Pharmaceutics, Vol 12, Iss 5, p 450 (2020)

Subject Terms: inclusion body, matrix metalloproteinase-9, mmp9 knock-out mice, functional nanoparticle, immunogenicity, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/12/5/450; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/a623558307664d1fa5364f9e6b825c6f

Neutrophils and Activated Macrophages Control Mucosal Immunity by Proteolytic Cleavage of Antileukoproteinase

Authors: Jennifer Vandooren, Pieter Goeminne, Lise Boon, Estefania Ugarte-Berzal, Vasily Rybakin, Paul Proost, Ahmed M. Abu El-Asrar, Ghislain Opdenakker

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: matrix metalloproteinases, proteases, antileukoproteinase, secretory leukocyte peptidase inhibitor, matrix metalloproteinase-9, neutrophils, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.01154/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/50547c8d1fc44a569362d95d58659c67

Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis.

Authors: Estefania Ugarte-Berzal, Nele Berghmans, Lise Boon, Erik Martens, Jennifer Vandooren, Bénédicte Cauwe, Greet Thijs, Paul Proost, Jo Van Damme, Ghislain Opdenakker

Source: PLoS ONE, Vol 13, Iss 10, p e0197944 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC6166937?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/d0933f0f7fe743618d1d0832dff91c1f

Endotoxemia shifts neutrophils with TIMP-free gelatinase B/MMP-9 from bone marrow to the periphery and induces systematic upregulation of TIMP-1

Authors: Jennifer Vandooren, Wannes Swinnen, Estefania Ugarte-Berzal, Lise Boon, Daphne Dorst, Erik Martens, Ghislain Opdenakker

Source: Haematologica, Vol 102, Iss 10 (2017)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/8215; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/713c7fe08f8c4f7aa15edb6e98863899

The Biological Potential Hidden in Inclusion Bodies

Authors: Laia Gifre-Renom, Joaquin Seras-Franzoso, Diana Rafael, Fernanda Andrade, Olivia Cano-Garrido, Francesc Martinez-Trucharte, Estefania Ugarte-Berzal, Erik Martens, Lise Boon, Antonio Villaverde, Ghislain Opdenakker, Simó Schwartz, Anna Arís, Elena Garcia-Fruitós

Source: Pharmaceutics, Vol 12, Iss 2, p 157 (2020)

Subject Terms: inclusion body, polymeric micelle, stability, matrix metalloproteinase-9, in vitro, in vivo, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/12/2/157; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/24defb96d43a4bfa8cbcff300c34d9ed

α4β1 integrin associates with VEGFR2 in CLL cells and contributes to VEGF binding and intracellular signaling

Authors: Alejandra Gutiérrez-González, Noemí Aguilera-Montilla, Estefanía Ugarte-Berzal, Elvira Bailón, Isabel Cerro-Pardo, Clara Sánchez-Maroto, Lara García-Campillo, José A. García-Marco, Angeles García-Pardo

Source: Blood Advances, Vol 3, Iss 14, Pp 2144-2148 (2019)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2473952920306479; https://doaj.org/toc/2473-9529

Access URL: https://doaj.org/article/746904a9a0ee4fd6bb4630545a015d9a

Matrix metalloproteinase-9 is involved in chronic lymphocytic leukemia cell response to fludarabine and arsenic trioxide.

Authors: Irene Amigo-Jiménez, Elvira Bailón, Estefanía Ugarte-Berzal, Noemí Aguilera-Montilla, José A García-Marco, Angeles García-Pardo

Source: PLoS ONE, Vol 9, Iss 6, p e99993 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24956101/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/2cebfa6706cf4c8e9f6b47ea8fab24e6