HLA-DP on Epithelial Cells Enables Tissue Damage by NKp44+ Natural Killer Cells in Ulcerative Colitis

Authors: Akar, Alaa, Flemming, Cornelius, Felix, Flomm, Flosbach, Markus, Jäger, Julia, Jeromin, Niklas, Jung, Johannes, Ohms, Mareike, Reinshagen, Konrad, Rische, Johann, Sagebiel, Adrian, Sandfort, Deborah, Steinert, Fenja, Tomuschat, Christian, Wesche, Jasmin, Shifteh Abedian, Abraham, Clara, Achkar, Jean-Paul, Ahmad, Tariq, Alberts, Rudi, Alizadeh, Behrooz, Amininejad, Leila, Ananthakrishnan, Ashwin N., Andersen, Vibeke, Anderson, Carl A., Andrews, Jane M., Annese, Vito, Aumais, Guy, Baidoo, Leonard, Baldassano, Robert N., Bampton, Peter A., Barclay, Murray, Barrett, Jeffrey C., Bethge, Johannes, Bewshea, Claire, Bis, Joshua C., Bitton, Alain, BK, Thelma, Boucher, Gabrielle, Brain, Oliver, Brand, Stephan, Brant, Steven R., Cheon, Jae Hee, Chew, Angela, Cho, Judy H., Cleynen, Isabelle, Cohain, Ariella, Cooney, Rachel, Croft, Anthony, Daly, Mark J., D'Amato, Mauro, Danese, Silvio, Daryani, Naser Ebrahim, Datta, Lisa Wu, Degenhardt, Frauke, Denapiene, Goda, Denson, Lee A., Devaney, Kathy L., Dewit, Olivier, D'Inca, Renata, Drummond, Hazel E., Dubinsky, Marla, Duerr, Richard H., Edwards, Cathryn, Ellinghaus, David, Ellul, Pierre, Esaki, Motohiro, Essers, Jonah, Ferguson, Lynnette R., Festen, Eleonora A., Fleshner, Philip, Florin, Tim, Franchimont, Denis, Franke, Andre, Fuyuno, Yuta, Gearry, Richard, Georges, Michel, Gieger, Christian, Glas, Jürgen, Goyette, Philippe, Green, Todd, Griffiths, Anne M., Guthery, Stephen L., Hakonarson, Hakon, Halfvarson, Jonas, Hanigan, Katherine, Haritunians, Talin, Hart, Ailsa, Hawkey, Chris, Hayward, Nicholas K., Hedl, Matija, Henderson, Paul, Hold, Georgina L., Hong, Myhunghee, Hu, Xinli, Huang, Hailiang, Hugot, Jean-Pierre, Hui, Ken Y., Imielinski, Marcin, Jazayeri, Omid, Jonaitis, Laimas, Jostins, Luke, Juyal, Garima, Chandra Juyal, Ramesh, Kalla, Rahul, Karlsen, Tom H., Kennedy, Nicholas A., Khan, Mohammed Azam, Kim, Won Ho, Kitazono, Takanari, Kiudelis, Gediminas, Kubo, Michiaki, Kugathasan, Subra, Kupcinskas, Limas, Lamb, Christopher A., de Lange, Katrina M., Latiano, Anna, Laukens, Debby, Lawrance, Ian C., Lee, James C., Lees, Charlie W., Leja, Marcis, Lewis, Nina, Van Limbergen, Johan, Lionetti, Paolo, Liu, Jimmy Z., Louis, Edouard, Luo, Yang, Mahy, Gillian, Malekzadeh, Masoud Mohammad, Malekzadeh, Reza, Mansfield, John, Marriott, Suzie, Massey, Dunecan, Mathew, Christopher G., Matsui, Toshiyuki, McGovern, Dermot P.B., van der Meulen, Andrea, Midha, Vandana, Milgrom, Raquel, Mirzaei, Samaneh, Mitrovic, Mitja, Montgomery, Grant W., Mowat, Craig, Müller, Christoph, Newman, William G., Ng, Aylwin, Ng, Siew C., Evelyn Ng, Sok Meng, Nikolaus, Susanna, Ning, Kaida, Nöthen, Markus, Oikonomou, Ioannis, Okou, David, Orchard, Timothy R., Palmieri, Orazio, Parkes, Miles, Phillips, Anne, Ponsioen, Cyriel Y., Potocnik, Urõs, Poustchi, Hossein, Prescott, Natalie J., Proctor, Deborah D., Radford-Smith, Graham, Rahier, Jean- Francois, Regueiro, Miguel, Reinisch, Walter, Rieder, Florian, Rioux, John D., Roberts, Rebecca, Rogler, Gerhard, Russell, Richard K., Sanderson, Jeremy D., Sans, Miquel, Satsangi, Jack, Schadt, Eric E., Scharl, Michael, Schembri, John, Schreiber, Stefan, Schumm, L. Philip, Scott, Regan, Seielstad, Mark, Shah, Tejas, Sharma, Yashoda, Silverberg, Mark S., Simmons, Alison, Simms, Lisa A., Singh, Abhey, Skieceviciene, Jurgita, van Sommeren, Suzanne, Song, Kyuyoung, Sood, Ajit, Spain, Sarah L., Steinhart, A. Hillary, Stempak, Joanne M., Stronati, Laura, Sung, Joseph J.Y., Targan, Stephan R., Taylor, Kirstin M., Theatre, Emilie, Torkvist, Leif, Torres, Esther A., Tremelling, Mark, Uhlig, Holm H., Umeno, Junji, Vahedi, Homayon, Vasiliauskas, Eric, Velde, Anje ter, Ventham, Nicholas T., Vermeire, Severine, Verspaget, Hein W., De Vos, Martine, Walters, Thomas, Wang, Kai, Wang, Ming-Hsi, Weersma, Rinse K., Wei, Zhi, Whiteman, David, Wijmenga, Cisca, Wilson, David C., Winkelmann, Juliane, Wong, Sunny H., Xavier, Ramnik J., Yamazaki, Keiko, Yang, Suk-Kyun, Ye, Byong Duk, Zeissig, Sebastian, Zhang, Bin, Zhang, Clarence K., Zhang, Hu, Zhang, Wei, Zhao, Hongyu, Zhao, Zhen Z., Baumdick, Martin E., Niehrs, Annika, Schwerk, Maria, Hinrichs, Ole, Jordan-Paiz, Ana, Padoan, Benedetta, Wegner, Lucy H.M., Schloer, Sebastian, Zecher, Britta F., Malsy, Jakob, Joshi, Vinita R., Illig, Christin, Schröder-Schwarz, Jennifer, Möller, Kimberly J., Martin, Maureen P., Yuki, Yuko, Ozawa, Mikki, Sauter, Jürgen, Schmidt, Alexander H., Perez, Daniel, Giannou, Anastasios D., Carrington, Mary, Davis, Randall S., Schumacher, Udo, Sauter, Guido, Huber, Samuel, Puelles, Victor G., Melling, Nathaniel, Altfeld, Marcus, Bunders, Madeleine J.

Source: In Gastroenterology October 2023 165(4):946-962

Increased Effectiveness of Early Therapy With Anti-Tumor Necrosis Factor-α vs an Immunomodulator in Children With Crohn's Disease

Authors: Walters, Thomas D., Kim, Mi-Ok, Denson, Lee A., Griffiths, Anne M., Dubinsky, Marla, Markowitz, James, Baldassano, Robert, Crandall, Wallace, Rosh, Joel, Pfefferkorn, Marian, Otley, Anthony, Heyman, Melvin B., LeLeiko, Neal, Baker, Susan, Guthery, Stephen L., Evans, Jonathan, Ziring, David, Kellermayer, Richard, Stephens, Michael, Mack, David, Oliva-Hemker, Maria, Patel, Ashish S., Kirschner, Barbara, Moulton, Dedrick, Cohen, Stanley, Kim, Sandra, Liu, Chunyan, Essers, Jonah, Kugathasan, Subra, Hyams, Jeffrey S.

Source: In Gastroenterology February 2014 146(2):383-391

Association of Linear Growth Impairment in Pediatric Crohn's Disease and a Known Height Locus: A Pilot Study.

Authors: Lee, Jessica J.¹ Jessica.lee@childrens.harvard.edu, Essers, Jonah B.^1,2, Kugathasan, Subra³, Escher, Johanna C.⁴, Lettre, Guillaume⁵, Butler, Johannah L.⁶, Stephens, Michael C.⁷, Ramoni, Marco F.^8,9, Grand, Richard J.^1,10, Hirschhorn, Joel^2,6

Source: Annals of Human Genetics. Nov2010, Vol. 74 Issue 6, p489-497. 9p. 3 Charts.

Subject Terms: *ETIOLOGY of diseases, *CROHN'S disease, *INFLAMMATORY bowel diseases, *GENETIC polymorphisms, *GENE frequency

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Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors: Jostins, Luke, Ripke, Stephan, Weersma, Rinse K., Duerr, Richard H., McGovern, Dermot P., Hui, Ken Y., Lee, James C., Philip Schumm, L., Sharma, Yashoda, Anderson, Carl A., Essers, Jonah, Mitrovic, Mitja, Ning, Kaida, Cleynen, Isabelle, Theatre, Emilie, Spain, Sarah L., Raychaudhuri, Soumya, Goyette, Philippe, Wei, Zhi, Abraham, Clara

Source: Nature. 11/1/2012, Vol. 491 Issue 7422, p119-124. 6p. 1 Chart, 2 Graphs.

Subjects: INFLAMMATORY bowel diseases, CROHN'S disease, ULCERATIVE colitis, PHENOTYPES, AUTOPHAGY, GENETICS

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976 Early Onset Crohn's Disease Exhibit Distinct Allele Architecture Differences and Reveal New IBD Loci

Authors: Kugathasan, Subra, Dubinsky, Marla, Guthery, Stephen L., Okou, David T., Bose, Promita, Zwick, Michael E., Cutler, David J., Waters, Jon P., Hyams, Jeffrey S., Baldassano, Robert, Stephens, Michael C., Heyman, Melvin B., Griffiths, Anne M., Crandall, Wallace, Markowitz, James, Essers, Jonah B., Snapper, Scott B., Walters, Thomas D., Aronow, Bruce J., Denson, Lee

Source: In Gastroenterology May 2013 144(5) Supplement 1:S

829 Early Anti-TNFα Therapy Is Superior to Early Immunomodulator Therapy in Newly Diagnosed Children With Crohn's Disease

Authors: Hyams, Jeffrey S., Kim, Mi-Ok, Denson, Lee, Griffiths, Anne M., Dubinsky, Marla, Markowitz, James, Baldassano, Robert, Crandall, Wallace, Rosh, Joel R., Pfefferkorn, Marian D., Otley, Anthony R., Heyman, Melvin B., Leleiko, Neal S., Baker, Susan S., Guthery, Stephen L., Evans, Jonathan, Ziring, David, Kellermayer, Richard, Stephens, Michael C., Mack, David R., Oliva-Hemker, Maria, Essers, Jonah B., Patel, Ashish S., Kirschner, Barbara S., Moulton, Dedrick E., Cohen, Stanley A., Liu, Chunyan, Kugathasan, Subra, Walters, Thomas D.

Source: In Gastroenterology May 2013 144(5) Supplement 1:S

162 Genetics, Serologies, and Smoking Predict Highly Morbid Crohn's Disease in Erroneously Diagnosed UC Patients

Authors: Essers, Jonah B., Ripke, Stephan, Neale, Bejamin, Xavier, Ramnik J., Vu, Michelle, Dubinsky, Marla, Rotter, Jerome I., Targan, Stephan R., McGovern, Dermot P., Daly, Mark J.

Source: In Gastroenterology May 2012 142(5) Supplement 1:S

138 Effect of Deep Ulceration at Diagnostic Colonoscopy on Initial Therapy and One Year Outcome in Children With Crohn's Disease

Authors: Hyams, Jeffrey S., Kim, Mi-Ok, Denson, Lee, Stephens, Michael C., Markowitz, James, Griffiths, Anne M., Crandall, Wallace, Essers, Jonah B., Baldassano, Robert, Dubinsky, Marla, Rosh, Joel R., Pfefferkorn, Marian D., Kim, Sandra C., Otley, Anthony R., Kellermayer, Richard, Heyman, Melvin B., Leleiko, Neal S., Baker, Susan S., Guthery, Stephen L., Evans, Jonathan, Ziring, David, Kugathasan, Subra, Walters, Thomas D.

Source: In Gastroenterology May 2012 142(5) Supplement 1:S

The Utility of Genetics in Classifying Ulcerative Colitis and Crohn's Disease Patients

Authors: Essers, Jonah B., Cole, Elisabeth B., Dubinsky, Marla, Haritunians, Talin, Korzenik, Joshua R., McGovern, Dermot P., Sands, Bruce E., Targan, Stephan R., Taylor, Kent D., Teleten, Nick, Xavier, Ramnik J., Daly, Mark J., Rotter, Jerome I., Silverberg, Mark S.

Source: In Gastroenterology 2011 140(5) Supplement 1:S

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