Hazard assessment of nanomaterials: how to meet the requirements for (next generation) risk assessment

Authors: Eleonora Marta Longhin, Ivan Rios-Mondragon, Espen Mariussen, Congying Zheng, Martí Busquets, Agnieszka Gajewicz-Skretna, Ole-Bendik Hofshagen, Neus Gómez Bastus, Victor Franco Puntes, Mihaela Roxana Cimpan, Sergey Shaposhnikov, Maria Dusinska, Elise Rundén-Pran

Source: Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-31 (2024)

Subject Terms: Hazard assessment, Next generation risk assessment, Nanomaterials, New approach methodologies, Safe and sustainable by design, Toxicology. Poisons, RA1190-1270, Industrial hygiene. Industrial welfare, HD7260-7780.8

File Description: electronic resource

Relation: https://doaj.org/toc/1743-8977

Access URL: https://doaj.org/article/9a10290c447748f5a48e4cd3331833ba

Population pharmacokinetic modeling of CSF to blood clearance: prospective tracer study of 161 patients under work-up for CSF disorders

Authors: Markus Herberg Hovd, Espen Mariussen, Hilde Uggerud, Aslan Lashkarivand, Hege Christensen, Geir Ringstad, Per Kristian Eide

Source: Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-14 (2022)

Subject Terms: Cerebrospinal fluid, Clearance, Gadobutrol, Brain metabolites, Intrathecal administration, Intrathecal drugs, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2045-8118

Access URL: https://doaj.org/article/b92176d348f54b60bf6d79f4bb783667

Glioblastoma microenvironment contains multiple hormonal and non-hormonal growth-stimulating factors

Authors: Daniel Dahlberg, Jutta Rummel, Sonia Distante, Gustavo Antonio De Souza, Maria Ekman Stensland, Espen Mariussen, Helge Rootwelt, Øyvind Voie, Bjørnar Hassel

Source: Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-11 (2022)

Subject Terms: Glioblastoma, Cyst fluid, Growth factors, Erythropoietin, Insulin-like growth factor, Testosterone, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2045-8118

Access URL: https://doaj.org/article/e69371f043db4d08bc1725606ce160bb

The colony forming efficiency assay for toxicity testing of nanomaterials—Modifications for higher-throughput

Authors: Elise Rundén-Pran, Espen Mariussen, Naouale El Yamani, Elisabeth Elje, Eleonora Marta Longhin, Maria Dusinska

Source: Frontiers in Toxicology, Vol 4 (2022)

Subject Terms: nanomaterials, cytotoxicity, cell viability, colony formation, CFE, 12-well format, Toxicology. Poisons, RA1190-1270

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/ftox.2022.983316/full; https://doaj.org/toc/2673-3080

Access URL: https://doaj.org/article/323d16bd0a264659a179d9d682a3f63d

Different Sensitivity of Advanced Bronchial and Alveolar Mono- and Coculture Models for Hazard Assessment of Nanomaterials

Authors: Elisabeth Elje, Espen Mariussen, Erin McFadden, Maria Dusinska, Elise Rundén-Pran

Source: Nanomaterials, Vol 13, Iss 3, p 407 (2023)

Subject Terms: NAMs—new approach methodologies, ALI—air–liquid interface, genotoxicity, BEAS-2B, A549, NM-300K, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2079-4991/13/3/407; https://doaj.org/toc/2079-4991

Access URL: https://doaj.org/article/0416e4f50b98495fbc67f5447fba364e

NanoSolveIT Project: Driving nanoinformatics research to develop innovative and integrated tools for in silico nanosafety assessment

Authors: Antreas Afantitis, Georgia Melagraki, Panagiotis Isigonis, Andreas Tsoumanis, Dimitra Danai Varsou, Eugenia Valsami-Jones, Anastasios Papadiamantis, Laura-Jayne A. Ellis, Haralambos Sarimveis, Philip Doganis, Pantelis Karatzas, Periklis Tsiros, Irene Liampa, Vladimir Lobaskin, Dario Greco, Angela Serra, Pia Anneli Sofia Kinaret, Laura Aliisa Saarimäki, Roland Grafström, Pekka Kohonen, Penny Nymark, Egon Willighagen, Tomasz Puzyn, Anna Rybinska-Fryca, Alexander Lyubartsev, Keld Alstrup Jensen, Jan Gerit Brandenburg, Stephen Lofts, Claus Svendsen, Samuel Harrison, Dieter Maier, Kaido Tamm, Jaak Jänes, Lauri Sikk, Maria Dusinska, Eleonora Longhin, Elise Rundén-Pran, Espen Mariussen, Naouale El Yamani, Wolfgang Unger, Jörg Radnik, Alexander Tropsha, Yoram Cohen, Jerzy Leszczynski, Christine Ogilvie Hendren, Mark Wiesner, David Winkler, Noriyuki Suzuki, Tae Hyun Yoon, Jang-Sik Choi, Natasha Sanabria, Mary Gulumian, Iseult Lynch

Source: Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 583-602 (2020)

Subject Terms: Nanoinformatics, Computational toxicology, Hazard assessment, Engineered nanomaterials, (quantitative) Structure–activity relationships, Integrated approach for testing and assessment, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2001037019305112; https://doaj.org/toc/2001-0370

Access URL: https://doaj.org/article/81b6870ad37945198bc7dfd358f34de2

Clinical application of intrathecal gadobutrol for assessment of cerebrospinal fluid tracer clearance to blood

Authors: Per K. Eide, Espen Mariussen, Hilde Uggerud, Are H. Pripp, Aslan Lashkarivand, Bjørnar Hassel, Hege Christensen, Markus Herberg Hovd, Geir Ringstad

Source: JCI Insight, Vol 6, Iss 9 (2021)

Subject Terms: Neuroscience, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/57f10cd73b99400c8023365d570d6f46

Advanced Respiratory Models for Hazard Assessment of Nanomaterials—Performance of Mono-, Co- and Tricultures

Authors: Laura Maria Azzurra Camassa, Elisabeth Elje, Espen Mariussen, Eleonora Marta Longhin, Maria Dusinska, Shan Zienolddiny-Narui, Elise Rundén-Pran

Source: Nanomaterials, Vol 12, Iss 15, p 2609 (2022)

Subject Terms: 3D lung model, air–liquid interface, nanotoxicology, NM-300K, tricultures, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2079-4991/12/15/2609; https://doaj.org/toc/2079-4991

Access URL: https://doaj.org/article/f09e6511810e4e42896208b95697c973

Sea Bass Primary Cultures versus RTgill-W1 Cell Line: Influence of Cell Model on the Sensitivity to Nanoparticles

Authors: Alba Jimeno-Romero, Frederik Gwinner, Michelle Müller, Espen Mariussen, Manu Soto, Yvonne Kohl

Source: Nanomaterials, Vol 11, Iss 11, p 3136 (2021)

Subject Terms: nanoparticles, gills, titanium dioxide, silver, polystyrene, protein corona, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2079-4991/11/11/3136; https://doaj.org/toc/2079-4991

Access URL: https://doaj.org/article/4a6afb86cc2840b3baa70b3368ba2312

Genotoxicity of Nanomaterials: Advanced In Vitro Models and High Throughput Methods for Human Hazard Assessment—A Review

Authors: Yvonne Kohl, Elise Rundén-Pran, Espen Mariussen, Michelle Hesler, Naouale El Yamani, Eleonora Marta Longhin, Maria Dusinska

Source: Nanomaterials, Vol 10, Iss 10, p 1911 (2020)

Subject Terms: nanomaterials, genotoxicity, in vitro 3D models, high throughput methods, miniaturization, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2079-4991/10/10/1911; https://doaj.org/toc/2079-4991

Access URL: https://doaj.org/article/8cc53abe0f394ff7b215d8563aa07897

Hepato(Geno)Toxicity Assessment of Nanoparticles in a HepG2 Liver Spheroid Model

Authors: Elisabeth Elje, Espen Mariussen, Oscar H. Moriones, Neus G. Bastús, Victor Puntes, Yvonne Kohl, Maria Dusinska, Elise Rundén-Pran

Source: Nanomaterials, Vol 10, Iss 3, p 545 (2020)

Subject Terms: advanced in vitro model, comet assay, genotoxicity, hepatotoxicity, liver spheroids, nanoparticles, 3d culture, hepg2, Chemistry, QD1-999

File Description: electronic resource

Relation: https://www.mdpi.com/2079-4991/10/3/545; https://doaj.org/toc/2079-4991

Access URL: https://doaj.org/article/297e06d56ac8496a933e88c168644dda

Episodic discharge of lead, copper and antimony from a Norwegian small arm shooting range.

Authors: Arnljot Einride Strømseng, Marita Ljønes, Loella Bakka, Espen Mariussen

Source: Journal of Environmental Monitoring; Jun2009, Vol. 11 Issue 6, p1259-1267, 9p

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In Vitro Toxicity of Tetrabromobisphenol-A on Cerebellar Granule Cells: Cell Death, Free Radical Formation, Calcium Influx and Extracellular Glutamate.

Authors: Trine Reistad¹, Espen Mariussen², Avi Ring¹, Frode Fonnum³

Source: Toxicological Sciences. Apr2007, Vol. 96 Issue 2, p268-278. 11p.

Subject Terms: *GLUTAMIC acid, *FREE radical reactions, *CELL death, *REACTIVE oxygen species