Interferon Gamma Release Assay and Tuberculin Skin Test Performance in Pregnant Women Living With and Without HIV

Authors: Kaplan, Samantha R., Escudero, Jaclyn N., Mecha, Jerphason, Richardson, Barbra A., Maleche-Obimbo, Elizabeth, Matemo, Daniel, Kinuthia, John, John-Stewart, Grace C., LaCourse, Sylvia M.

Source: Journal of acquired immune deficiency syndromes. 89(1):98-107

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157703358.0x000001&indx=1&recIds=ETOCvdc_100157703358.0x000001

Key influences on the decision to initiate PrEP among adolescent girls and young women within routine maternal child health and family planning clinics in Western Kenya

Authors: Rogers, Zoe, Pintye, Jillian, Kinuthia, John, O'Malley, Gabrielle, Abuna, Felix, Escudero, Jaclyn, Mugambi, Melissa, Awuor, Mercy, Dollah, Annabell, Dettinger, Julia C., Kohler, Pamela, John-Stewart, Grace, Beima-Sofie, Kristin

Source: AIDS care. 34(3):363-370

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100145253487.0x000001&indx=1&recIds=ETOCvdc_100145253487.0x000001

CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study

Authors: Huang, Zhen, LaCourse, Sylvia M, Kay, Alexander W, Stern, Joshua, Escudero, Jaclyn N, Youngquist, Brady M, Zheng, Wenshu, Vambe, Debrah, Dlamini, Muyalo, Mtetwa, Godwin, Cranmer, Lisa M, Njuguna, Irene, Wamalwa, Dalton C, Maleche-Obimbo, Elizabeth, Catanzaro, Donald G, Lyon, Christopher J, John-Stewart, Grace, DiNardo, Andrew, Mandalakas, Anna M, Ning, Bo, Hu, Tony Y ^*

Source: In The Lancet Microbe July 2022 3(7):e482-e492

Diminished Mycobacterium tuberculosis–specific T-cell Responses During Pregnancy in Women With HIV and Receiving Isoniazid Preventive Therapy.

Authors: Saha, Aparajita^1,2,3 (AUTHOR), Escudero, Jaclyn N³ (AUTHOR), Layouni, Troy⁴ (AUTHOR), Mecha, Jerphason⁵ (AUTHOR), Maleche-Obimbo, Elizabeth^3,6 (AUTHOR), Matemo, Daniel⁵ (AUTHOR), Kinuthia, John^3,7,8 (AUTHOR), John-Stewart, Grace^1,3,9,10 (AUTHOR), Richardson, Barbra A^3,11 (AUTHOR), LaCourse, Sylvia M^1,3,9 (AUTHOR), Shah, Javeed A^1,2,4 (AUTHOR)

Source: Open Forum Infectious Diseases. Feb2025, Vol. 12 Issue 2, p1-11. 11p.

Subject Terms: *INTERFERON gamma release tests, *PREGNANT women, *MYCOBACTERIUM tuberculosis, *T cells, *CD4 antigen

Influences on Early Discontinuation and Persistence of Daily Oral PrEP Use Among Kenyan Adolescent Girls and Young Women: A Qualitative Evaluation From a PrEP Implementation Program

Authors: Pintye, Jillian, O'Malley, Gabrielle, Kinuthia, John, Abuna, Felix, Escudero, Jaclyn N., Mugambi, Melissa, Awuor, Mercy, Dollah, Annabell, Dettinger, Julia C., Kohler, Pamela, John-Stewart, Grace, Beima-Sofie, Kristin

Source: Journal of acquired immune deficiency syndromes. 86(4):e83-e89

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182528328.0x000001&indx=1&recIds=ETOCvdc_100182528328.0x000001

Isoniazid preventive therapy during infancy does not adversely affect growth among HIV-exposed uninfected children: Secondary analysis of data from a randomized controlled trial.

Authors: Cherkos, Ashenafi Shumey, LaCourse, Sylvia M., Enquobahrie, Daniel A., Escudero, Jaclyn N., Mecha, Jerphason, Matemo, Daniel, Kinuthia, John, Iribarren, Sarah J., John-Stewart, Grace

Source: PLoS ONE; 8/16/2024, Vol. 19 Issue 8, p1-13, 13p

Subject Terms: INFECTION prevention, RANDOMIZED controlled trials, ISONIAZID, INFANTS, LINEAR statistical models

Hybrid Immunity to SARS-CoV-2 During Pregnancy Provides More Durable Infant Antibody Responses Compared to Natural Infection Alone.

Authors: LaCourse, Sylvia M, Wetzler, Erica A, Aurelio, Morgan C, Escudero, Jaclyn N, Selke, Stacy S, Greninger, Alexander L, Goecker, Erin A, Barnes, Sarina R, Arnould, Isabel S, Pérez-Osorio, Ailyn C, Richardson, Barbra A, Kachikis, Alisa, Englund, Janet A, Drake, Alison L

Source: Journal of Infectious Diseases; 6/15/2024, Vol. 229 Issue 6, p1728-1739, 12p

Subject Terms: ANTIBODY formation, PREGNANT women, SARS-CoV-2, PREGNANCY, INFANTS

Maternal breastfeeding and education impact infant growth and development more than in-utero HIV/antiretroviral therapy exposure in context of universal antiretroviral therapy.

Authors: Cherkos, Ashenafi S., LaCourse, Sylvia M., Kinuthia, John, Mecha, Jerphason, Enquobahrie, Daniel A., Escudero, Jaclyn N., John-Stewart, Grace

Source: AIDS (02699370); Mar2024, Vol. 38 Issue 4, p537-546, 10p

Hybrid Immunity to Severe Acute Respiratory Syndrome Coronavirus 2 During Pregnancy Provides More Durable Infant Antibody Responses Compared to Natural Infection or Vaccination Alone.

Authors: LaCourse, Sylvia M, Wetzler, Erica A, Aurelio, Morgan C, Escudero, Jaclyn N, Selke, Stacy S, Greninger, Alexander L, Goecker, Erin A, Barnes, Sarina R, Arnould, Isabel S, Pérez-Osorio, Ailyn C, Richardson, Barbra A, Kachikis, Alisa, Englund, Janet A, Drake, Alison L

Source: Journal of Infectious Diseases; 4/15/2024, Vol. 229 Issue 4, p1241-1243, 3p

Subject Terms: SARS-CoV-2, ANTIBODY formation

Impact of Human Immunodeficiency Virus and Peripartum Period on Mycobacterium tuberculosis Infection Detection.

Authors: Escudero, Jaclyn N¹ (AUTHOR), Mecha, Jerphason² (AUTHOR), Richardson, Barbra A^1,3 (AUTHOR), Maleche-Obimbo, Elizabeth^1,4 (AUTHOR), Matemo, Daniel⁵ (AUTHOR), Kinuthia, John^1,5,6 (AUTHOR), John-Stewart, Grace^1,7,8,9 (AUTHOR) gjohn@uw.edu, LaCourse, Sylvia M^1,7,8 (AUTHOR) sylvial2@uw.edu

Source: Journal of Infectious Diseases. Dec2023, Vol. 228 Issue 12, p1709-1719. 11p.

Subject Terms: *PERINATAL period, *HIV, *MYCOBACTERIUM tuberculosis, *MYCOBACTERIAL diseases, *TUBERCULIN test

Geographic Terms: KENYA

Sensitive Blood-Based Detection of HIV-1 and Mycobacterium tuberculosis Peptides for Disease Diagnosis by Immuno-Affinity Liquid Chromatography-Tandem Mass Spectrometry: A Method Development and Proof-of-Concept Study.

Authors: Lin Li, Lyon, Christopher J., LaCourse, Sylvia M., Wenshu Zheng, Stern, Joshua, Escudero, Jaclyn N., Murithi, Wilfred Bundi, Njagi, Lilian, John-Stewart, Grace, Hawn, Thomas R., Nduba, Videlis, Abdelgaliel, Wael, Tombler, Thomas, Horne, David, Li Jiang, Hu, Tony Y.

Source: Clinical Chemistry; Dec2023, Vol. 69 Issue 12, p1409-1419, 11p

Maternal HIV Status and Risk of Infant Mycobacterium tuberculosisInfection as Measured by Tuberculin Skin Test

Authors: Mecha, Jerphason, Escudero, Jaclyn N., Richardson, Barbra A., Maleche-Obimbo, Elizabeth, Matemo, Daniel, Kinuthia, John, John-Stewart, Grace, LaCourse, Sylvia M.

Source: The Pediatric Infectious Disease Journal; March 2024, Vol. 43 Issue: 3 p250-256, 7p

Severe acute respiratory syndrome coronavirus 2 seroprevalence and longitudinal antibody response following natural infection in pregnancy: A prospective cohort study.

Authors: Drake, Alison L, Escudero, Jaclyn N, Aurelio, Morgan C, Wetzler, Erica A, Ellington, Sascha R, Zapata, Lauren B, Galang, Romeo R, Snead, Margaret C, Yamamoto, Krissy, Salerno, Carol C, Richardson, Barbra A, Greninger, Alexander L, Kachikis, Alisa B, Englund, Janet A, LaCourse, Sylvia M

Source: Women's Health (17455057); 8/24/2023, p1-11, 11p

Subject Terms: RESEARCH, SEROPREVALENCE, ANTIGEN-antibody reactions, COVID-19, IMMUNIZATION, COVID-19 vaccines, CROSS-sectional method, DESCRIPTIVE statistics, RESEARCH funding, LONGITUDINAL method, PREGNANCY

Demand creation for HIV testing services: A systematic review and meta-analysis.

Authors: Wagner, Anjuli D., Njuguna, Irene N., Neary, Jillian, Lawley, Kendall A., Louden, Diana K. N., Tiwari, Ruchi, Jiang, Wenwen, Kalu, Ngozi, Burke, Rachael M., Mangale, Dorothy, Obermeyer, Chris, Escudero, Jaclyn N., Bulterys, Michelle A., Waters, Chloe, Mollo, Bastien, Han, Hannah, Barr-DiChiara, Magdalena, Baggaley, Rachel, Jamil, Muhammad S., Shah, Purvi

Source: PLoS Medicine; 3/21/2023, Vol. 19 Issue 3, p1-41, 41p, 1 Color Photograph, 2 Diagrams, 2 Charts, 2 Graphs

Subject Terms: DIAGNOSIS of HIV infections, LABOR demand, OBJECTIVITY in journalism, INCENTIVE (Psychology), RANDOMIZED controlled trials

Company/Entity: WORLD Health Organization

Cumulative Mycobacterium tuberculosis Infection Incidence (Measured Primarily by Tuberculin Skin Test) Among Infants With Human Immunodeficiency Virus Exposure: Observational Follow-up of an Isoniazid Prophylaxis Trial.

Authors: LaCourse, Sylvia M^1,2 sylvial2@uw.edu, Escudero, Jaclyn N², Mecha, Jerphason³, Warr, A J⁴, Richardson, Barbra A^2,5, Carimo, Naziat², Cranmer, Lisa M^6,7, Maleche-Obimbo, Elizabeth^2,8, Matemo, Daniel³, Kinuthia, John^2,3,9, Hawn, Thomas R¹, John-Stewart, Grace^1,2,10,11

Source: Clinical Infectious Diseases. 12/15/2022, Vol. 75 Issue 12, p2253-2256. 4p.

Subject Terms: *SCIENTIFIC observation, *CONFIDENCE intervals, *ISONIAZID, *RANDOMIZED controlled trials, *MYCOBACTERIUM tuberculosis, *TUBERCULIN test, *STATISTICAL sampling, *HIV

Diagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples.

Authors: Zheng, Wenshu, LaCourse, Sylvia M., Song, Bofan, Singh, Dhiraj Kumar, Khanna, Mayank, Olivo, Juan, Stern, Joshua, Escudero, Jaclyn N., Vergara, Carlos, Zhang, Fangfang, Li, Shaobai, Wang, Shu, Cranmer, Lisa M., Huang, Zhen, Bojanowski, Christine M., Bao, Duran, Njuguna, Irene, Xiao, Yating, Wamalwa, Dalton C., Nguyen, Duc T.

Source: Nature Biomedical Engineering; Aug2022, Vol. 6 Issue 8, p979-991, 13p

A Randomized Controlled Trial of Isoniazid to Prevent Mycobacterium tuberculosis Infection in Kenyan Human Immunodeficiency Virus–Exposed Uninfected Infants.

Authors: LaCourse, Sylvia M, Richardson, Barbra A, Kinuthia, John, Warr, A J, Maleche-Obimbo, Elizabeth, Matemo, Daniel, Cranmer, Lisa M, Mecha, Jerphason, Escudero, Jaclyn N, Hawn, Thomas R, John-Stewart, Grace

Source: Clinical Infectious Diseases; Jul2021, Vol. 73 Issue 2, pe337-e344, 8p

Subject Terms: TUBERCULOSIS epidemiology, TUBERCULOSIS prevention, TUBERCULOSIS risk factors, MATERNAL exposure, INTERFERON gamma release tests, RELATIVE medical risk, CONFIDENCE intervals, ISONIAZID, TREATMENT effectiveness, RANDOMIZED controlled trials, TUBERCULIN test, DESCRIPTIVE statistics, DISEASE prevalence, MYCOBACTERIUM tuberculosis, STATISTICAL sampling, ADVERSE health care events, VERTICAL transmission (Communicable diseases), HIV, CHILDREN

Geographic Terms: KENYA

Community Perceptions About Use of Pre-exposure Prophylaxis Among Adolescent Girls and Young Women in Kenya.

Authors: Escudero, Jaclyn N., Dettinger, Julia C., Pintye, Jillian, Kinuthia, John, Lagat, Harison, Abuna, Felix, Kohler, Pamela, Baeten, Jared M., O'Malley, Gabrielle, John-Stewart, Grace C., Beima-Sofie, Kristin M.

Source: JANAC: Journal of the Association of Nurses in AIDS Care; Nov/Dec2020, Vol. 31 Issue 6, p669-677, 9p

High pre-exposure prophylaxis awareness and willingness to pay for pre-exposure prophylaxis among young adults in Western Kenya: results from a population-based survey.

Authors: Begnel, Emily R, Escudero, Jaclyn, Mugambi, Melissa, Mugwanya, Kenneth, Kinuthia, John, Beima-Sofie, Kristin, Dettinger, Julia C, Baeten, Jared M, John-Stewart, Grace, Pintye, Jillian

Source: International Journal of STD & AIDS; Apr2020, Vol. 31 Issue 5, p454-459, 6p, 1 Chart, 1 Graph

Subject Terms: PRE-exposure prophylaxis, WILLINGNESS to pay, YOUNG adults, AWARENESS

Geographic Terms: KENYA, NAIROBI (Kenya)

Infant TB Infection Prevention Study (iTIPS): a randomised trial protocol evaluating isoniazid to prevent M. tuberculosis infection in HIV-exposed uninfected children.

Authors: LaCourse, Sylvia M., Richardson, Barbra A., Kinuthia, John, Warr, A. J., Maleche-Obimbo, Elizabeth, Matemo, Daniel, Cranmer, Lisa M., Escudero, Jaclyn N., Hawn, Thomas R., John-Stewart, Grace C.

Source: BMJ Open; Jan2020, Vol. 10 Issue 1, p1-9, 9p