Clinician variability in the diagnosis and treatment of aspergillus fumigatus-related conditions in cystic fibrosis: An international survey

Authors: Hong, Gina, Desai, Sameer, Moss, Richard B., Eschenhagen, Patience, Quon, Bradley S., Schwarz, Carsten

Source: In Journal of Cystic Fibrosis January 2022 21(1):136-142

Clinical impact of levofloxacin inhalation solution in cystic fibrosis patients in a real-world setting

Authors: Schwarz, Carsten, Grehn, Claudia, Temming, Svenja, Holz, Frederik, Eschenhagen, Patience Ndidi

Source: In Journal of Cystic Fibrosis November 2021 20(6):1035-1039

Human Anti-fungal Th17 Immunity and Pathology Rely on Cross-Reactivity against Candida albicans

Authors: Bacher, Petra, Hohnstein, Thordis, Beerbaum, Eva, Röcker, Marie, Blango, Matthew G., Kaufmann, Svenja, Röhmel, Jobst, Eschenhagen, Patience, Grehn, Claudia, Seidel, Kathrin, Rickerts, Volker, Lozza, Laura, Stervbo, Ulrik, Nienen, Mikalai, Babel, Nina, Milleck, Julia, Assenmacher, Mario, Cornely, Oliver A., Ziegler, Maren, Wisplinghoff, Hilmar, Heine, Guido, Worm, Margitta, Siegmund, Britta, Maul, Jochen, Creutz, Petra, Tabeling, Christoph, Ruwwe-Glösenkamp, Christoph, Sander, Leif E., Knosalla, Christoph, Brunke, Sascha, Hube, Bernhard, Kniemeyer, Olaf, Brakhage, Axel A., Schwarz, Carsten, Scheffold, Alexander

Source: In Cell 7 March 2019 176(6):1340-1355

S3-Leitlinie: Lungenerkrankung bei Mukoviszidose – Pseudomonas aeruginosa. (German)

Alternate Title: CF Lung Disease – a German S3 Guideline: Pseudomonas aeruginosa. (English)

Authors: Schwarz, Carsten, Bend, Jutta, Hebestreit, Helge, Hogardt, Michael, Hügel, Christian, Illing, Stephan, Mainz, Jochen G., Rietschel, Ernst, Schmidt, Sebastian, Schulte-Hubbert, Bernhard, Sitter, Helmut, Wielpütz, Marc Oliver, Hammermann, Jutta, Baumann, Ingo, Brunsmann, Frank, Dieninghoff, Doris, Eber, Ernst, Ellemunter, Helmut, Eschenhagen, Patience, Evers, Caroline

Source: Pneumologie; Jun2024, Vol. 78 Issue 6, p367-399, 33p

Dynamics of abdominal symptoms during the start of a new therapy with elexacaftor/ tezacaftor/ivacaftor using the novel CFAbd-day2day questionnaire.

Authors: Mainz, Jochen G., Barucha, Anton, Pu Huang, Bechinger, Lilith, Duckstein, Franziska, Polte, Louise, Sadrieh, Pauline, Nährlich, Lutz, Eickmeier, Olaf, Van Dullemen, Suzanne, Eschenhagen, Patience, Schwarz, Carsten, Lüth, Stefan, Zagoya, Carlos, Graepler-Mainka, Ute

Source: Frontiers in Pharmacology; 2023, p1-12, 12p

Subject Terms: ABDOMEN, CYSTIC fibrosis, SYMPTOMS, CYSTIC fibrosis transmembrane conductance regulator, PATIENT monitoring

Company/Entity: UNITED States. Food & Drug Administration

Proliferative activity of antigen-specific CD154+ T cells against bacterial and fungal respiratory pathogens in cystic fibrosis decreases after initiation of highly effective CFTR modulator therapy.

Authors: Eschenhagen, Patience N., Bacher, Petra, Grehn, Claudia, Mainz, Jochen G., Scheffold, Alexander, Schwarz, Carsten

Source: Frontiers in Pharmacology; 2023, p1-8, 8p

Subject Terms: MUCOCILIARY system, T cells, CYSTIC fibrosis transmembrane conductance regulator, BACTERIAL cells, CYSTIC fibrosis, B cell receptors

Antibiotic Therapy for Pulmonary Exacerbations in Cystic Fibrosis—A Single-Centre Prospective Observational Study.

Authors: Schwarz, Carsten, Wimmer, Eliana, Holz, Frederik, Grehn, Claudia, Staab, Doris, Eschenhagen, Patience Ndidi

Source: Antibiotics (2079-6382); Apr2023, Vol. 12 Issue 4, p734, 16p

Subject Terms: CYSTIC fibrosis, C-reactive protein, LONGITUDINAL method, SCIENTIFIC observation, DISEASE exacerbation

Antigen specificity and cross-reactivity drive functionally diverse anti-Aspergillus fumigatus T cell responses in cystic fibrosis.

Authors: Schwarz, Carsten¹, Eschenhagen, Patience¹, Schmidt, Henrijette^2,3, Hohnstein, Thordis⁴, Iwert, Christina⁵, Grehn, Claudia⁶, Roehme, Jobst^1,7, Steinke, Eva^6,7,8, Stahl, Mirjam^6,7,8, Lozza, Laura⁹, Tikhonova, Ekaterina^2,3, Rosati, Elisa^2,3, Stervbo, Ulrik¹⁰, Babel, Nina^6,10, Mainz, Jochen G.¹¹, Wisplinghoff, Hilmar^12,13, Ebe, Frank^1,14, Lei-Jie Jia¹⁵, Blango, Matthew G.¹⁵, Hortschansky, Peter¹⁵

Source: Journal of Clinical Investigation. Mar2023, Vol. 133 Issue 5, p1-16. 16p.

Elexacaftor-Tezacaftor-Ivacaftor Treatment Reduces Abdominal Symptoms in Cystic Fibrosis-Early results Obtained With the CF-Specific CFAbd-Score.

Authors: Mainz, Jochen G., Zagoya, Carlos, Polte, Louise, Naehrlich, Lutz, Sasse, Lenny, Eickmeier, Olaf, Smaczny, Christina, Barucha, Anton, Bechinger, Lilith, Duckstein, Franziska, Kurzidim, Ludwik, Eschenhagen, Patience, Caley, Laura, Peckham, Daniel, Schwarz, Carsten

Source: Frontiers in Pharmacology; 6/3/2022, Vol. 13, p1-11, 11p

Subject Terms: APPETITE disorders, APPETITE, EXOCRINE pancreatic insufficiency, SYMPTOMS

Company/Entity: UNITED States. Food & Drug Administration

Genetic diversification of persistent Mycobacterium abscessus within cystic fibrosis patients.

Authors: Lewin, Astrid, Kamal, Elisabeth, Semmler, Torsten, Winter, Katja, Kaiser, Sandra, Schäfer, Hubert, Mao, Lei, Eschenhagen, Patience, Grehn, Claudia, Bender, Jennifer, Schwarz, Carsten

Source: Virulence; Dec 2021, Vol. 12 Issue 1, p2415-2429, 15p

Subject Terms: CYSTIC fibrosis, OPERONS, MYCOBACTERIUM, MYCOBACTERIAL diseases, GENETIC variation, LUNG infections, GENETIC mutation

Geographic Terms: BERLIN (Germany)

Genetic diversification of persistent Mycobacterium abscessuswithin cystic fibrosis patients

Authors: Lewin, Astrid, Kamal, Elisabeth, Semmler, Torsten, Winter, Katja, Kaiser, Sandra, Schäfer, Hubert, Mao, Lei, Eschenhagen, Patience, Grehn, Claudia, Bender, Jennifer, Schwarz, Carsten

Source: Virulence; December 2021, Vol. 12 Issue: 1 p2415-2429, 15p

Prospective Evaluation of Aspergillus fumigatus -Specific IgG in Patients With Cystic Fibrosis.

Authors: Eschenhagen, Patience, Grehn, Claudia, Schwarz, Carsten

Source: Frontiers in Cellular & Infection Microbiology; 1/22/2021, Vol. 11, pN.PAG-N.PAG, 8p

Subject Terms: CYSTIC fibrosis, ASPERGILLUS fumigatus, PULMONARY aspergillosis, RECEIVER operating characteristic curves, LUNG diseases, BURKHOLDERIA infections, DIAGNOSIS

Geographic Terms: AFRICA

Frequent Pet Contact as Risk Factor for Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis.

Authors: Grehn, Claudia, Eschenhagen, Patience, Temming, Svenja, Düesberg, Uta, Neumann, Konrad, Schwarz, Carsten

Source: Frontiers in Cellular & Infection Microbiology; 1/11/2021, Vol. 11, pN.PAG-N.PAG, 6p

Subject Terms: CYSTIC fibrosis, BURKHOLDERIA infections, PET care, ASPERGILLUS fumigatus, MYCOSES, PETS, CHI-squared test, PULMONARY aspergillosis

Therapie der Mukoviszidose – neue Medikamente geben Hoffnung. (German)

Alternate Title: Therapy of cystic fibrosis – new drugs give hope. (English)

Authors: Eschenhagen, Patience, Schwarz, Carsten

Source: DMW: Deutsche Medizinische Wochenschrift; 2020, Vol. 145 Issue 20, p1486-1489, 4p

Gene–Dose Effect of MEFV Gain-of-Function Mutations Determines ex vivo Neutrophil Activation in Familial Mediterranean Fever.

Authors: Stoler, Iris, Freytag, Judith, Orak, Banu, Unterwalder, Nadine, Henning, Stephan, Heim, Katrin, von Bernuth, Horst, Krüger, Renate, Winkler, Stefan, Eschenhagen, Patience, Seipelt, Eva, Mall, Marcus A., Foell, Dirk, Kessel, Christoph, Wittkowski, Helmut, Kallinich, Tilmann

Source: Frontiers in Immunology; 6/11/2020, p1-11, 11p

Subject Terms: FAMILIAL Mediterranean fever, GAIN-of-function mutations, ADENOSINE triphosphate, NEUTROPHILS, PYODERMA gangrenosum

Erratum: S3-Leitlinie: Lungenerkrankung bei Mukoviszidose – Pseudomonas aeruginosa. (German)

Alternate Title: CF Lung Disease – a German S3 Guideline: Pseudomonas aeruginosa. (English)

Authors: Schwarz, Carsten, Bend, Jutta, Hebestreit, Helge, Hogardt, Michael, Hügel, Christian, Illing, Stephan, Mainz, Jochen G., Rietschel, Ernst, Schmidt, Sebastian, Schulte-Hubbert, Bernhard, Sitter, Helmut, Wielpütz, Marc Oliver, Hammermann, Jutta, Baumann, Ingo, Brunsmann, Frank, Dieninghoff, Doris, Eber, Ernst, Ellemunter, Helmut, Eschenhagen, Patience, Evers, Caroline

Source: Pneumologie; Jun2024, Vol. 78 Issue 6, pe2-e2, 1p

Patienten mit zystischer Fibrose werden erwachsen. (German)

Alternate Title: Patients with cystic fibrosis become adults. (English)

Authors: Eschenhagen, Patience, Schwarz, Carsten

Source: Der Internist; Jan2019, Vol. 60 Issue 1, p98-108, 11p

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