Capsaicin ameliorate pulmonary fibrosis via antioxidant Nrf-2/ PPAR- γ pathway activation and inflammatory TGF-β1/ NF-κB/COX II pathway inhibition

Authors: Wesam H. Abdulaal, Hani Z. Asfour, Nawal Helmi, Hadeel Al Sadoun, Basmah Eldakhakhny, Nabil A. Alhakamy, Hani Mohammed Alqarni, Saeed Ali Mohammed Alzahrani, Mohamed A. El-Moselhy, Sara S. Sharkawi, Esam Mohamed Aboubakr

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: Capsaicin, bleomycin, Pirfenidone, pulmonary fibrosis, TGF-β1, PPAR-γ, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1333715/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/56e11dd5012f4fab9a7e4368e5bbdcde