Comparing research attitudes in Down syndrome and non‐Down syndrome research decision‐makers

Authors: Thuy V. Lu, Paola Campos, Sean Leader, Xavier Lee, Helena Xu, Eric Doran, Joshua D Grill, Ira T. Lott

Source: Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 3, Pp n/a-n/a (2024)

Subject Terms: clinical trials, Down syndrome, research attitudes, Research Attitudes Questionnaire, research registry, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8737

Access URL: https://doaj.org/article/5b729d016b114fc7a22e7bf67df263cc

Neurofilament light chain concentration mediates the association between regional medial temporal lobe structure and memory in adults with Down syndrome

Authors: Natalie DiProspero, Mithra Sathishkumar, John Janecek, Anna Smith, Liv McMillan, Melissa Petersen, Nicholas Tustison, David B. Keator, Eric Doran, Christy L. Hom, Dana Nguyen, Howard Andrews, Sharon Krinsky‐McHale, Adam M. Brickman, H. Diana Rosas, Florence Lai, Elizabeth Head, Mark Mapstone, Wayne Silverman, Ira T. Lott, Sid O'Bryant, Michael A. Yassa

Source: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 16, Iss 1, Pp n/a-n/a (2024)

Subject Terms: Alzheimer's disease, anterolateral entorhinal cortex, cognitive decline, dementia, Down syndrome, episodic memory, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8729

Access URL: https://doaj.org/article/7422d877af6a4072bb0972d4b84616f7

Increased plasma DYRK1A with aging may protect against neurodegenerative diseases

Authors: Jean M. Delabar, Julien Lagarde, Marta Fructuoso, Ammara Mohammad, Michel Bottlaender, Eric Doran, Ira Lott, Isabelle Rivals, Frederic A. Schmitt, Elizabeth Head, Marie Sarazin, Marie-Claude Potier

Source: Translational Psychiatry, Vol 13, Iss 1, Pp 1-8 (2023)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/2158-3188

Access URL: https://doaj.org/article/5d6a3bb197104b249fcbd404915e0cfc

Research attitudes in families of individuals with Down syndrome: importance for clinical trials

Authors: Ira T. Lott, Katharine A. Kirby, Eric Doran, Joshua D. Grill

Source: Alzheimer’s Research & Therapy, Vol 14, Iss 1, Pp 1-7 (2022)

Subject Terms: Down syndrome, Alzheimer disease, Trisomy 21, Research attitudes, Clinical trials, Survey, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/1758-9193

Access URL: https://doaj.org/article/b5cf787bc86e4480b1a5d2f9384bdc7a

Cerebrovascular pathology in Down syndrome and Alzheimer disease

Authors: Elizabeth Head, Michael J. Phelan, Eric Doran, Ronald C. Kim, Wayne W. Poon, Frederick A. Schmitt, Ira T. Lott

Source: Acta Neuropathologica Communications, Vol 5, Iss 1, Pp 1-9 (2017)

Subject Terms: Arteriolosclerosis, Atherosclerosis, Cerebral amyloid angiopathy, Trisomy 21, Vascular risk factors, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-017-0499-4; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/a782679066f042b2ae7d8bb0ad0be8f1

Distribution of microglial phenotypes as a function of age and Alzheimer's disease neuropathology in the brains of people with Down syndrome

Authors: Alessandra C. Martini, Alex M. Helman, Katie L. McCarty, Ira T. Lott, Eric Doran, Frederick A. Schmitt, Elizabeth Head

Source: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)

Subject Terms: IBA‐1, microglial morphology, neuroinflammation, posterior cingulate cortex, trisomy 21, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8729

Access URL: https://doaj.org/article/a3b3da3a233c4867a32e58d198bd1a5f

Cerebrospinal fluid biomarkers of Alzheimer's disease in a cohort of adults with Down syndrome

Authors: Rachel L. Henson, Eric Doran, Bradley T. Christian, Benjamin L. Handen, William E. Klunk, Florence Lai, Joseph H. Lee, H. Diana Rosas, Nicole Schupf, Shahid H. Zaman, Ira T. Lott, Anne M. Fagan

Source: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)

Subject Terms: Alzheimer's disease, biomarkers, cerebrospinal fluid, Down syndrome, amyloid, tau, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8729

Access URL: https://doaj.org/article/eefd689289e14cc593bda243f5711e1d

Down syndrome: Distribution of brain amyloid in mild cognitive impairment

Authors: David B. Keator, Michael J. Phelan, Lisa Taylor, Eric Doran, Sharon Krinsky‐McHale, Julie Price, Erin E. Ballard, William C. Kreisl, Christy Hom, Dana Nguyen, Margaret Pulsifer, Florence Lai, Diana H. Rosas, Adam M. Brickman, Nicole Schupf, Michael A. Yassa, Wayne Silverman, Ira T. Lott

Source: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)

Subject Terms: ABC‐DS, ADDS, Alzheimer's disease, amyloid, AV‐45, dementia, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8729

Access URL: https://doaj.org/article/c16ccc9be94a41aca7218ba22d136181

Brain amyloid and the transition to dementia in Down syndrome

Authors: David B. Keator, Eric Doran, Lisa Taylor, Michael J. Phelan, Christy Hom, Katherine Tseung, Theo G. M. vanErp, Steven G. Potkin, Adam M. Brickman, Diana H. Rosas, Michael A. Yassa, Wayne Silverman, Ira T. Lott

Source: Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 12, Iss 1, Pp n/a-n/a (2020)

Subject Terms: Alzheimer's, amyloid, classification, dementia, Down syndrome, positron emission tomography, Neurology. Diseases of the nervous system, RC346-429, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2352-8729

Access URL: https://doaj.org/article/f5b9b881f8e84813ba56f79abdebb6ac

Cognitive and Behavioral Domains That Reliably Differentiate Normal Aging and Dementia in Down Syndrome

Authors: Jordan P. Harp, Lisa M. Koehl, Kathryn L. Van Pelt, Christy L. Hom, Eric Doran, Elizabeth Head, Ira T. Lott, Frederick A. Schmitt

Source: Brain Sciences, Vol 11, Iss 9, p 1128 (2021)

Subject Terms: Down syndrome, dementia, cognition, functional independence, neuropsychological assessment, primary care, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3425/11/9/1128; https://doaj.org/toc/2076-3425

Access URL: https://doaj.org/article/4e4925e365a549edada5158a61980cdc

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