Production of large, defined genome modifications in rats by targeting rat embryonic stem cells

Authors: Jeffrey Lee, Jingjing Wang, Roxanne Ally, Sean Trzaska, Joseph Hickey, Alejo Mujica, Lawrence Miloscio, Jason Mastaitis, Brian Morse, Janell Smith, Amanda Atanasio, Eric Chiao, Henry Chen, Adrianna Latuszek, Ying Hu, David Valenzuela, Carmelo Romano, Brian Zambrowicz, Wojtek Auerbach

Source: Stem Cell Reports, Vol 18, Iss 1, Pp 394-409 (2023)

Subject Terms: rat, embryonic stem cells, genetic modification, germline transmission, disease models, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671122005458; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/88b937e03131464dbeca15f69d7100e2

Tissue-specific activation of gene expression by the Synergistic Activation Mediator (SAM) CRISPRa system in mice

Authors: Charleen Hunt, Suzanne A. Hartford, Derek White, Evangelos Pefanis, Timothy Hanna, Clarissa Herman, Jarrell Wiley, Heather Brown, Qi Su, Yurong Xin, Dennis Voronin, Hien Nguyen, Judith Altarejos, Keith Crosby, Jeffery Haines, Sarah Cancelarich, Meghan Drummond, Sven Moller-Tank, Ryan Malpass, Jacqueline Buckley, Maria del Pilar Molina-Portela, Gustavo Droguett, David Frendewey, Eric Chiao, Brian Zambrowicz, Guochun Gong

Source: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/17fb14b41cbb4fa7890fbff2faf8ff19

Assessment of the role of afucosylated glycoforms on the in vitro antibody-dependent phagocytosis activity of an antibody to Aβ aggregates

Authors: Allyson Kwiatkowski, Carl Co, Sei Kameoka, An Zhang, John Coughlin, Tom Cameron, Eric Chiao, Svetlana Bergelson, Cullen Schmid Mason

Source: mAbs, Vol 12, Iss 1 (2020)

Subject Terms: Antibody, IgG1, antibody-dependent cell-mediated phagocytosis, ADCP, phagocytosis, Fc effector function, Therapeutics. Pharmacology, RM1-950, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1942-0862; https://doaj.org/toc/1942-0870

Access URL: https://doaj.org/article/de7297e0eace436aacfb3a8b6386340a