Childhood Langerhans cell histiocytosis hematological involvement: severity associated with BRAFV600E loads

Authors: Devoldere, Catherine, Gourmel, Antoine, Lutun, Anne, Leglise, Sophie, Pellier, Isabelle, Proust, Stéphanie, Cheikh, Nathalie, Klein, Sébastien, Simon, Pauline, Verite, Cécile, Miaz, Leila, Bodet, Damien, Deparis, Marianna, Gaudichon, Jérémie, Dore, Eric, Kanold, Justyna, Briandet, Claire, Desplantes, Claire, Neuman, Florent, Adjaoud, Dalila, Armari-Alla, Corinne, Plantaz, Dominique, Perret, Cécile, Bruno, Bénedicte, Nelken, Brigitte, Piguet, Christophe, Bertrand, Yves, Garnier, Nathalie, Kebaili, Kamila, Ouachee, Marie, Coze, Carole, Curtillet, Catherine, Gentet, Jean-Claude, Michel, Gérard, Galambrun, Claire, Chastagner, Pascal, Boutroux, Hélène, Landman-Parker, Judith, Bodak, Nathalie, Leverger, Guy, Petit, Arnaud, Simonin, Mathieu, Tabone, Marie-Dominique, Bader-Meunier, Brigitte, Blanche, Stéphane, Castelle, Martin, Neven, Bénédicte, Bodemer, Christine, Perrin, Olivia Boccara, Aerts, Isabelle, Orbach, Daniel, Bourdeaut, Franck, Brugieres, Laurence, Dufour, Christelle, Minard, Véronique, Valteau-Couanet, Dominique, Blanc, Laurence, Millot, Frédéric, Guimard, Grégory, Pluchart, Claire, Bonneau, Jacinthe, Chappe, Céline, Taque, Sophie, Pertuisel, Sophie, Gandemer, Virginie, Probert, Jamie, Puiseux, Chloé, Buchbinder, Nimrod, Dumesnil, Cécile, Filhon, Bruno, Marie-Cardine, Aude, Schneider, Pascale, Berger, Claire, Thouvenin-Doulet, Sandrine, Entz-Werle, Natacha, Paillard, Catherine, Spiegel, Alexandra, Plat, Geneviève, Blouin, Pascale, Jourdain, Anne, Yvert-Guillebert, Marion, Jehanne, Mathilde, Benadiba, Joy, Soler, Christine, Poiree, Maryline, Haouy, Stéphanie, Sirvent, Nicolas, Saumet, Laure, Thalhammer, Julian ^{1, 2}, Jeziorski, Eric ³, Marec-Bérard, Perrine ¹, Barkaoui, Mohamed Aziz ⁴, Pagnier, Anne ⁵, Rohrlich, Pierre-Simon ⁶, Chevallier, Aurore ⁴, Carausu, Liana ⁷, Aladjidi, Nathalie ⁸, Rigaud, Charlotte ⁹, Leruste, Amaury ¹⁰, Azarnoush, Saba ¹¹, Lauvray, Thomas ¹², Le Louet, Solenne ⁴, Treguier, Pauline ¹⁴, Mansuy, Ludovic ¹⁵, Pasquet, Marlene ¹⁶, Olivier, Laura ¹⁶, Rome, Angélique ¹⁷, Saultier, Paul ¹⁷, Isfan, Fiorentina ¹⁸, Renard, Cécile ¹, Li Thiao Te, Valerie ¹⁹, Salmon, Alexandra ²⁰, Abou Chahla, Wadih ², Lambilliotte, Anne ², Stephan, Jean-Louis ²², Geissmann, Frederic ²³, Lejeune, Julien ²⁴, Mallebranche, Coralie ²⁵, Reguerre, Yves ²⁶, Grain, Audrey ²⁷, Thomas, Caroline ²⁷, Hélias-Rodzewicz, Zofia ²⁸, Moshous, Despina ²⁹, Fenneteau, Odile ³⁰, Coulomb-L’Hermine, Aurore ³¹, Lapillonne, Hélène ³², de Saint-Basile, Geneviève ³³, Emile, Jean-François ²⁸, Héritier, Sébastien ⁴, Donadieu, Jean ^{4, ∗}

Source: In Blood 6 March 2025 145(10):1061-1073

Hypoxia-driven heterogeneous expression of α5 integrin in glioblastoma stem cells is linked to HIF-2α

Authors: Messé, Mélissa, Bernhard, Chloé, Foppolo, Sophie, Thomas, Lionel, Marchand, Patrice, Herold-Mende, Christel, Idbaih, Ahmed, Kessler, Horst, Etienne-Selloum, Nelly, Ochoa, Charles, Tambar, Uttam K., Elati, Mohamed, Laquerriere, Patrice, Entz-Werle, Natacha, Martin, Sophie, Reita, Damien, Dontenwill, Monique

Source: In BBA - Molecular Basis of Disease December 2024 1870(8)

Overcoming the limits of pediatric brain tumor radiotherapy: The use of preclinical 3D models

Alternate Title: Repousser les limites de la radiothérapie des tumeurs cérébrales pédiatriques : utilisation des modèles précliniques tridimensionnels (French)

Authors: Czuba, Élodie, Deschuyter, Marlène, Entz-Werlé, Natacha, Noël, Georges, Burckel, Hélène

Source: In Cancer / Radiothérapie October 2024 28(5):424-434

Chemo-immunotherapy with dinutuximab beta in patients with relapsed/progressive high-risk neuroblastoma: does chemotherapy backbone matter?

Authors: Raiser, Patricia, Schleiermacher, Gudrun, Gambart, Marion, Dumont, Benoit, Defachelles, Anne-Sophie, Thebaud, Estelle, Tandonnet, Julie, Pasqualini, Claudia, Proust, Stéphanie, Entz-Werle, Natacha, Aerts, Isabelle, Ndounga-Diakou, Lee A., Petit, Arnaud, Puiseux, Chloe, Khanfar, Camille, Rouger, Jeremie, Mansuy, Ludovic, Benadiba, Joy, Millot, Frédéric, Pluchart, Claire, Laghouati, Salim, Geoerger, Birgit, Vassal, Gilles, Valteau-Couanet, Dominique, Berlanga, Pablo

Source: In European Journal of Cancer May 2024 202

Clinical trial inclusion in patients with relapsed/refractory neuroblastoma following the European Precision Cancer Medicine trial MAPPYACTS

Authors: Chaix, Jordane, Schleiermacher, Gudrun, Corradini, Nadège, André, Nicolas, Thebaud, Estelle, Gambart, Marion, Defachelles, Anne-Sophie, Entz-Werle, Natacha, Chastagner, Pascal, De Carli, Émilie, Ducassou, Stéphane, Landman-Parker, Judith, Adam-de-Beaumais, Tiphaine, Larive, Alicia, Michiels, Stefan, Vassal, Gilles, Valteau-Couanet, Dominique, Geoerger, Birgit, Berlanga, Pablo

Source: In European Journal of Cancer April 2024 201

Pediatric Tumors and Developmental Anomalies: A French Nationwide Cohort Study

Authors: Semeraro, Michaela, Fouquet, Cyrielle, Vial, Yoann, Amiel, Jeanne, Galmiche, Louise, Cretolle, Célia, Blanc, Thomas, Jolaine, Valérie, Garcelon, Nicolas, Entz-Werle, Natacha, Pellier, Isabelle, Vérité, Cécile, Sophie Taque, Coulomb, Aurore, Petit, Arnaud, Corradini, Nadège, Bouazza, Naim, Lacour, Brigitte, Clavel, Jacqueline, Brugières, Laurence, Bourdeaut, Franck, Sarnacki, Sabine

Source: In The Journal of Pediatrics August 2023 259

Challenges in glioblastoma research: focus on the tumor microenvironment

Authors: Bikfalvi, Andreas, da Costa, Cristine Alves, Avril, Tony, Barnier, Jean-Vianney, Bauchet, Luc, Brisson, Lucie, Cartron, Pierre Francois, Castel, Hélène, Chevet, Eric, Chneiweiss, Hervé, Clavreul, Anne, Constantin, Bruno, Coronas, Valérie, Daubon, Thomas, Dontenwill, Monique, Ducray, Francois, Entz-Werlé, Natacha, Figarella-Branger, Dominique, Fournier, Isabelle, Frenel, Jean-Sébastien, Gabut, Mathieu, Galli, Thierry, Gavard, Julie, Huberfeld, Gilles, Hugnot, Jean-Philippe, Idbaih, Ahmed, Junier, Marie-Pierre, Mathivet, Thomas, Menei, Philippe, Meyronet, David, Mirjolet, Céline, Morin, Fabrice, Mosser, Jean, Moyal, Elisabeth Cohen-Jonathan, Rousseau, Véronique, Salzet, Michel, Sanson, Marc, Seano, Giorgio, Tabouret, Emeline, Tchoghandjian, Aurélie, Turchi, Laurent, Vallette, Francois M., Vats, Somya, Verreault, Maité, Virolle, Thierry

Source: In Trends in Cancer January 2023 9(1):9-27

Pharmacokinetics of oral vinorelbine in French children with recurrent or progressive primary low‐grade glioma

Authors: Hamimed, Mourad, Gattacceca, Florence, André, Nicolas, Tresch‐Bruneel, Emmanuelle, Probst, Alicia, Chastagner, Pascal, Pagnier, Anne, De Carli, Emilie, Entz‐Werlé, Natacha, Grill, Jacques, Aerts, Isabelle, Frappaz, Didier, Bertozzi‐Salamon, Anne‐Isabelle, Solas, Caroline, Leblond, Pierre

Source: British journal of clinical pharmacology. 88(5):2096-2117

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100146672555.0x000001&indx=1&recIds=ETOCvdc_100146672555.0x000001

An appraisal of the frequency and severity of noninfectious manifestations in primary immunodeficiencies: A study of a national retrospective cohort of 1375 patients over 10 years

Authors: Abou-Chahla, Wadih, Adoue, Daniel, Aladjidi, Nathalie, Armari-Alla, Corinne, Barlogis, Vincent, Bayart, Sophie, Bertrand, Yves, Blanche, Stéphane, Bodet, Damien, Bonnotte, Bernard, Borie, Raphaël, Boutard, Patrick, Boutboul, David, Briandet, Claire, Brion, Jean-Paul, Brouard, Jacques, Carausu, Liana, Castelle, Martin, Cathebras, Pascal, Catherinot, Emilie, Cheikh, Nathalie, Cheminant, Morgane, Cohen-Beaussant, Sarah, Comont, Thibault, Couderc, Louis-Jean, Cougoul, Pierre, Couillault, Gérard, Crevon, Lionel, Demonchy, Elisa, Deville, Anne, Devoldere, Catherine, Dore, Eric, Dulieu, Fabienne, Durieu, Isabelle, Entz-Werle, Natacha, Fieschi, Claire, Fouyssac, Fanny, Frange, Pierre, Gajdos, Vincent, Galicier, Lionel, Gandemer, Virginie, Gardembas, Martine, Gaud, Catherine, Grosbois, Bernard, Guffroy, Aurélien, Guitton, Corinne, Guillerm, Gaëlle, Hachulla, Eric, Hamidou, Mohamed, Haro, Sophie, Hatchuel, Yves, Hermine, Olivier, Hoarau, Cyrille, Hot, Arnaud, Humbert, Sébastien, Jaccard, Arnaud, Jais, Jean-Philippe, Jannier, Sarah, Jacquot, Serge, Jaussaud, Roland, Jeandel, Pierre-Yves, Jeziorski, Eric, Kebaili, Kamila, Korganow, Anne-Sophie, Lambotte, Olivier, Lanternier, Fanny, Larroche, Claire, Launay, David, Le Moigne, Emmanuelle, Le Quellec, Alain, Le Moing, Vincent, Lebranchu, Yvon, Lecuit, Marc, Lefèvre, Guillaume, Lelièvre, Jean-Daniel, Lemal, Richard, Li-Thiao-Te, Valérie, Lortholary, Olivier, Luca, Luminita, Mallebranche, Coralie, Malphettes, Marion, Marie-Cardine, Aude, Martin-Silva, Nicolas, Masseau, Agathe, Mazingue, Françoise, Merlin, Etienne, Michel, Gérard, Millot, Frédéric, Miot, Charline, Monlibert, Béatrice, Monpoux, Fabrice, Moshous, Despina, Mouthon, Luc, Münzer, Martine, Navarro, Robert, Neven, Bénédicte, Nouar, Dalila, Nove-Josserand, Raphaële, Oksenhendler, Eric, Ouachée-Chardin, Marie, Pagnier, Anne, Pasquet, Marlène, Pellier, Isabelle, Perel, Yves, Perlat, Antoinette, Piguet, Christophe, Plantaz, Dominique, Rivière, Sophie, Roblot, Pascal, Rohrlich, Pierre-Simon, Royer, Bruno, Salle, Valéry, Sarrot-Reynauld, Françoise, Servettaz, Amélie, Stephan, Jean-Louis, Schleinitz, Nicolas, Sokol, Harry, Suarez, Felipe, Swiader, Laure, Taque, Sophie, Thomas, Caroline, Tournilhac, Olivier, Thumerelle, Caroline, Vannier, Jean-Pierre, Viallard, Jean-François, Alligon, Mickaël, Mahlaoui, Nizar, Courteille, Virginie, Costes, Laurence, Afonso, Veronica, Randrianomenjanahary, Philippe, de Vergnes, Nathalie, Ranohavimparany, Anja, Vo, Duy, Hafsa, Inès, Bach, Perrine, Benoit, Vincent, Garcelon, Nicolas, Fischer, Alain

Source: In The Journal of Allergy and Clinical Immunology June 2022 149(6):2116-2125

Hematopoietic cell transplantation in severe combined immunodeficiency: The SCETIDE 2006-2014 European cohort

Authors: Lankester, Arjan C., Neven, Benedicte, Mahlaoui, Nizar, von Asmuth, Erik G.J., Courteille, Virginie, Alligon, Mikael, Albert, Michael H., Serra, Isabelle Badell, Bader, Peter, Balashov, Dmitry, Beier, Rita, Bertrand, Yves, Blanche, Stephane, Bordon, Victoria, Bredius, Robbert G., Cant, Andrew, Cavazzana, Marina, Diaz-de-Heredia, Cristina, Dogu, Figen, Ehlert, Karoline, Entz-Werle, Natacha, Fasth, Anders, Ferrua, Francesca, Ferster, Alina, Formankova, Renata, Friedrich, Wilhelm, Gonzalez-Vicent, Marta, Gozdzik, Jolanta, Güngör, Tayfun, Hoenig, Manfred, Ikinciogullari, Aydan, Kalwak, Krzysztof, Kansoy, Savas, Kupesiz, Alphan, Lanfranchi, Arnalda, Lindemans, Caroline A., Meisel, Roland, Michel, Gerard, Miranda, Nuno A.A., Moraleda, Jose, Moshous, Despina, Pichler, Herbert, Rao, Kanchan, Sedlacek, Petr, Slatter, Mary, Soncini, Elena, Speckmann, Carsten, Sundin, Mikael, Toren, Amos, Vettenranta, Kim, Worth, Austen, Yeşilipek, Mehmet A., Zecca, Marco, Porta, Fulvio, Schulz, Ansgar, Veys, Paul, Fischer, Alain, Gennery, Andrew R.

Source: In The Journal of Allergy and Clinical Immunology May 2022 149(5):1744-1754

Lenvatinib with etoposide plus ifosfamide in patients with refractory or relapsed osteosarcoma (ITCC-050): a multicentre, open-label, multicohort, phase 1/2 study

Authors: Gaspar, Nathalie ^*, Venkatramani, Rajkumar, Hecker-Nolting, Stefanie, Melcon, Soledad Gallego, Locatelli, Franco, Bautista, Francisco, Longhi, Alessandra, Lervat, Cyril, Entz-Werle, Natacha, Casanova, Michela, Aerts, Isabelle, Strauss, Sandra J, Thebaud, Estelle, Morland, Bruce, Nieto, Adela Cañete, Marec-Berard, Perrine, Gambart, Marion, Rossig, Claudia, Okpara, Chinyere E, He, Cixin, Dutta, Lea, Campbell-Hewson, Quentin

Source: In The Lancet Oncology September 2021 22(9):1312-1321

Chimeric protein EWS::FLI1 drives cell proliferation in Ewing Sarcoma viaaberrant expression of KCNN1/SK1 and dysregulation of calcium signaling

Authors: Dupuy, Maryne, Gueguinou, Maxime, Postec, Anaïs, Brion, Régis, Tesfaye, Robel, Mullard, Mathilde, Regnier, Laura, Amiaud, Jérôme, Hubsch, Clémence, Potier-Cartereau, Marie, Chantôme, Aurélie, Brounais-Le Royer, Bénédicte, Baud’huin, Marc, Georges, Steven, Lamoureux, François, Ory, Benjamin, Entz-Werlé, Natacha, Delattre, Olivier, Rédini, Françoise, Vandier, Christophe, Verrecchia, Franck

Source: Oncogene; January 2025, Vol. 44 Issue: 2 p79-91, 13p

Clinical impact of large genomic explorations at diagnosis in 198 pediatric solid tumors: a monocentric study aiming practical feasibility of precision oncology.

Authors: Simon, Juliette, Reita, Damien, Guerin, Eric, Lhermitte, Benoit, Weingertner, Noelle, Lefebvre, François, Karanian, Marie, Masliah-Planchon, Julien, Lindner, Veronique, Onea, Alina, Jannier, Sarah, Salmon, Alexandra, Bergthold, Guillaume, Vincent, Florence, Deschuyter, Marlène, Barbaza, Marie-Odile, Entz-Werlé, Natacha

Source: BMC Cancer; 10/21/2024, Vol. 24 Issue 1, p1-18, 18p

Cabozantinib in patients with advanced Ewing sarcoma or osteosarcoma (CABONE): a multicentre, single-arm, phase 2 trial

Authors: Italiano, Antoine ^*, Mir, Olivier, Mathoulin-Pelissier, Simone, Penel, Nicolas, Piperno-Neumann, Sophie, Bompas, Emmanuelle, Chevreau, Christine, Duffaud, Florence, Entz-Werlé, Natacha, Saada, Esma, Ray-Coquard, Isabelle, Lervat, Cyril, Gaspar, Nathalie, Marec-Berard, Perrine, Pacquement, Hélène, Wright, John, Toulmonde, Maud, Bessede, Alban, Crombe, Amandine, Kind, Michèle, Bellera, Carine, Blay, Jean-Yves

Source: In The Lancet Oncology March 2020 21(3):446-455

Denosumab for treating aneurysmal bone cysts in children

Authors: Raux, Sébastien, Bouhamama, Amine, Gaspar, Nathalie, Brugières, Laurence, Entz-Werlé, Natacha, Mallet, Cindy, Dijoud, Frédérique, Gouin, François, Marec-Bérard, Perrine

Source: In Orthopaedics & Traumatology: Surgery & Research October 2019 105(6):1181-1185

Intérêt du denosumab dans le traitement des kystes osseux anévrysmatiques de l’enfant

Alternate Title: Denosumab for treating aneurysmal bone cysts in children (English)

Authors: Raux, Sébastien, Bouhamama, Amine, Gaspar, Nathalie, Brugières, Laurence, Entz-werlé, Natacha, Mallet, Cindy, Dijoud, Frédérique, Gouin, François, Marec-Bérard, Perrine

Source: In Revue de Chirurgie Orthopedique et Traumatologique October 2019 105(6):769-773

Prognostic relevance of clinical and molecular risk factors in children with high-risk medulloblastoma treated in the phase II trial PNET HR+5

Authors: Dufour, Christelle, Foulon, Stephanie, Geoffray, Anne, Masliah-Planchon, Julien, Figarella-Branger, Dominique, Bernier-Chastagner, Valerie, Padovani, Laetitia, Guerrini-Rousseau, Léa, Faure-Conter, Cecile, Icher, Celine, Bertozzi, Anne-Isabelle, Leblond, Pierre, Akbaraly, Tasnime, Bourdeaut, Franck, André, Nicolas, Chappé, Celine, Schneider, Pascale, De Carli, Emilie, Chastagner, Pascal, Berger, Claire, Lejeune, Julien, Soler, Christine, Entz-Werlé, Natacha, Delisle, Marie-Bernadette

Source: Neuro-oncology. 23(7):1163-1172

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132704632.0x000001&indx=1&recIds=ETOCvdc_100132704632.0x000001

Long‐term follow‐up of children with risk organ‐negative Langerhans cell histiocytosis after 2‐chlorodeoxyadenosine treatment

Authors: Barkaoui, Mohamed‐Aziz, Queheille, Emma, Aladjidi, Nathalie, Plat, Geneviève, Jeziorski, Eric, Moshous, Despina, Lambilliotte, Anne, Kebaili, Kamila, Pacquement, Hélène, Leverger, Guy, Mansuy, Ludovic, Entz‐Werlé, Natacha, Bodet, Damien, Schneider, Pascale, Pagnier, Anne, Lutun, Anne, Gillibert‐Yvert, Marion, Millot, Fréderic, Toutain, Fabienne, Reguerre, Yves, Thomas, Caroline, Tazi, Abdelatif, Emile, Jean‐François, Donadieu, Jean, Héritier, Sébastien

Source: British journal of haematology. 191(5):825-834

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100127373071.0x000001&indx=1&recIds=ETOCvdc_100127373071.0x000001

Results of methotrexate-etoposide-ifosfamide based regimen (M-EI) in osteosarcoma patients included in the French OS2006/sarcome-09 study

Authors: Gaspar, Nathalie, Occean, Bob-Valéry, Pacquement, Hélène, Bompas, Emmanuelle, Bouvier, Corine, Brisse, Hervé J., Castex, Marie-Pierre, Cheurfa, Nadir, Corradini, Nadège, Delaye, Jessy, Entz-Werlé, Natacha, Gentet, Jean-Claude, Italiano, Antoine, Lervat, Cyril, Marec-Berard, Perrine, Mascard, Eric, Redini, Françoise, Saumet, Laure, Schmitt, Claudine, Tabone, Marie-Dominique, Verite-Goulard, Cécile, Le Deley, Marie-Cécile, Piperno-Neumann, Sophie, Brugieres, Laurence

Source: In European Journal of Cancer January 2018 88:57-66

Engineering Novel 3D Models to Recreate High‐Grade Osteosarcoma and its Immune and Extracellular Matrix Microenvironment

Authors: Pierrevelcin, Marina, Flacher, Vincent, Mueller, Christopher G., Vauchelles, Romain, Guerin, Eric, Lhermitte, Benoît, Pencreach, Erwan, Reisch, Andreas, Muller, Quentin, Doumard, Layal, Boufenghour, Wacym, Klymchenko, Andrey S., Foppolo, Sophie, Nazon, Charlotte, Weingertner, Noelle, Martin, Sophie, Briandet, Claire, Laithier, Véronique, Di Marco, Antonio, Bund, Laurent, Obrecht, Adeline, Villa, Pascal, Dontenwill, Monique, Entz‐Werlé, Natacha

Source: Advanced healthcare materials. 11(19)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165221741.0x000001&indx=1&recIds=ETOCvdc_100165221741.0x000001