Emerging therapeutics: The imidazo[1,2-b]pyridazine scaffold as a novel drug candidate for eumycetoma, a neglected tropical disease

Authors: Elkheir, Lamis Yahia Mohamed ^{a, b, c}, Delaye, Pierre-Olivier ^c, Penichon, Mélanie ^c, Eadie, Kimberly ^d, Mohamed, Magdi Awadalla ^e, Besson, Pierre ^f, Chesnay, Adélaïde ^g, Desoubeaux, Guillaume ^g, Roger, Sébastien ^f, van de Sande, Wendy Wilhelmina Johanna ^d, Fahal, Ahmed Hassan ^a, Enguehard-Gueiffier, Cécile ^{c, ⁎}

Source: In European Journal of Medicinal Chemistry 5 November 2024 277

Cassia sieberiana root bark used in traditional medicine in Togo: Anthelmintic property against Haemonchus contortus and tannins composition

Authors: Kpabi, Iwaba, Munsch, Thibaut, Agban, Amégninou, Théry-Koné, Isabelle, Dorat, Joelle, Boudesocque-Delaye, Leslie, Delaye, Pierre-Olivier, Neveu, Cédric, Lanoue, Arnaud, Enguehard-Gueiffier, Cécile

Source: In South African Journal of Botany December 2022 151 Part B:549-558

Imidazo[1,2-b]pyridazine as privileged scaffold in medicinal chemistry: An extensive review

Authors: Garrido, Amanda, Vera, Gonzalo, Delaye, Pierre-Olivier, Enguehard-Gueiffier, Cécile

Source: In European Journal of Medicinal Chemistry 15 December 2021 226

Bioinspired imidazo[1,2-a:4,5-c’]dipyridines with dual antiproliferative and anti-migrative properties in human cancer cells: The SAR investigation

Authors: Alzain, Abdulrahim A., Brisson, Lucie, Delaye, Pierre-Olivier, Pénichon, Mélanie, Chadet, Stéphanie, Besson, Pierre, Chevalier, Stéphan, Allouchi, Hassan, Mohamed, Magdi A., Roger, Sébastien, Enguehard-Gueiffier, Cécile

Source: In European Journal of Medicinal Chemistry 5 June 2021 218

Natural deep eutectic solvent formulations for spirulina: Preparation, intensification, and skin impact

Authors: Wils, Laura, Leman-Loubière, Charlotte, Bellin, Nicolas, Clément-Larosière, Barbara, Pinault, Michelle, Chevalier, Stéphan, Enguehard-Gueiffier, Cécile, Bodet, Charles, Boudesocque-Delaye, Leslie

Source: In Algal Research June 2021 56

ATR-IR spectroscopy for rapid quantification of water content in deep eutectic solvents

Authors: Elderderi, Suha, Leman-Loubière, Charlotte, Wils, Laura, Henry, Sandra, Bertrand, Dominique, Byrne, Hugh J., Chourpa, Igor, Enguehard-Gueiffier, Cécile, Munnier, Emilie, Elbashir, Abdalla A., Boudesocque-Delaye, Leslie, Bonnier, Franck

Source: In Journal of Molecular Liquids 1 August 2020 311

Imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1 decrease the parasite burden in mice with acute toxoplasmosis

Authors: Moine, Espérance, Moiré, Nathalie, Dimier-Poisson, Isabelle, Brunet, Kévin, Couet, William, Colas, Cyril, Van Langendonck, Nathalie, Enguehard-Gueiffier, Cécile, Gueiffier, Alain, Héraut, Bruno, Denevault-Sabourin, Caroline, Debierre-Grockiego, Françoise

Source: In International Journal for Parasitology June 2018 48(7):561-568

Quality control of commercial cranberry products: HPTLC-densitometry a new deal

Authors: Boudesocque-Delaye, Leslie, Lanoue, Arnaud, Dorat, Joëlle, Bruyère, Frank, Gueiffier, Alain, Enguehard-Gueiffier, Cécile

Source: In Food Control April 2018 86:214-223

Discovery of imidazo[1,2-a]pyridine-based anthelmintic targeting cholinergic receptors of Haemonchus contortus

Authors: N'Guessan, Jean-Paul Déto Ursul, Delaye, Pierre-Olivier, Pénichon, Mélanie, Charvet, Claude L., Neveu, Cédric, Ouattara, Mahama, Enguehard-Gueiffier, Cécile, Gueiffier, Alain, Allouchi, Hassan

Source: In Bioorganic & Medicinal Chemistry 15 December 2017 25(24):6695-6706

Imidazo[1, 2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1 decrease the parasite burden in mice with acute toxoplasmosis

Authors: Moine, Espérance, Moiré, Nathalie, Dimier-Poisson, Isabelle, Brunet, Kévin, Couet, William, Colas, Cyril, Van Langendonck, Nathalie, Enguehard-Gueiffier, Cécile, Gueiffier, Alain, Héraut, Bruno, Denevault-Sabourin, Caroline, Debierre-Grockiego, Françoise

Source: International journal for parasitology. 48(7):561-568

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083354436.0x000001&indx=1&recIds=ETOCvdc_100083354436.0x000001

One-step preparative isolation of aristolochic acids by strong ion-exchange centrifugal partition chromatography

Authors: Abdelgadir, Abdelgadir A., Boudesocque-Delaye, Leslie, Thery-Koné, Isabelle, Gueiffier, Alain, Ahmed, Elhadi M., Enguehard-Gueiffier, Cécile

Source: In Separation and Purification Technology 17 December 2015 156 Part 2:444-449

Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1

Authors: Moine, Espérance, Dimier-Poisson, Isabelle, Enguehard-Gueiffier, Cécile, Logé, Cédric, Pénichon, Mélanie, Moiré, Nathalie, Delehouzé, Claire, Foll-Josselin, Béatrice, Ruchaud, Sandrine, Bach, Stéphane, Gueiffier, Alain, Debierre-Grockiego, Françoise, Denevault-Sabourin, Caroline

Source: In European Journal of Medicinal Chemistry 13 November 2015 105:80-105

Imidazo[1, 2-b]pyridazine as privileged scaffold in medicinal chemistry: An extensive review

Authors: Garrido, Amanda, Vera, Gonzalo, Delaye, Pierre-Olivier, Enguehard-Gueiffier, Cécile

Source: European journal of medicinal chemistry. 226

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Discovery of imidazo[1, 2-a]pyridine-based anthelmintic targeting cholinergic receptors of Haemonchus contortus

Authors: N'Guessan, Jean-Paul Déto Ursul, Delaye, Pierre-Olivier, Pénichon, Mélanie, Charvet, Claude L., Neveu, Cédric, Ouattara, Mahama, Enguehard-Gueiffier, Cécile, Gueiffier, Alain, Allouchi, Hassan

Source: Bioorganic & medicinal chemistry. 25(24):6695-6706

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100096895523.0x000001&indx=1&recIds=ETOCvdc_100096895523.0x000001

Anti-inflammatory activity of Crateva adansonii DC on keratinocytes infected by Staphylococcus aureus: From traditional practice to scientific approach using HPTLC-densitometry

Authors: Ahama-Esseh, Kplolali, Bodet, Charles, Quashie-Mensah-Attoh, Akossiwa, Garcia, Magali, Théry-Koné, Isabelle, Dorat, Joelle, De Souza, Comlan, Enguehard-Gueiffier, Cécile, Boudesocque-Delaye, Leslie

Source: Journal of ethnopharmacology. 204:26-35

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100060686169.0x000001&indx=1&recIds=ETOCvdc_100060686169.0x000001

A small-molecule cell-based screen led to the identification of biphenylimidazoazines with highly potent and broad-spectrum anti-apicomplexan activity

Authors: Moine, Espérance, Denevault-Sabourin, Caroline, Debierre-Grockiego, Françoise, Silpa, Laurence, Gorgette, Olivier, Barale, Jean-Christophe, Jacquiet, Philippe, Brossier, Fabien, Gueiffier, Alain, Dimier-Poisson, Isabelle, Enguehard-Gueiffier, Cécile

Source: In European Journal of Medicinal Chemistry 7 January 2015 89:386-400

3-Biphenylimidazo[1,2-a]pyridines or [1,2-b]pyridazines and analogues, novel Flaviviridae inhibitors

Authors: Enguehard-Gueiffier, Cécile, Musiu, Simone, Henry, Nicolas, Véron, Jean-Baptiste, Mavel, Sylvie, Neyts, Johan, Leyssen, Pieter, Paeshuyse, Jan, Gueiffier, Alain

Source: In European Journal of Medicinal Chemistry June 2013 64:448-463

Domino 6-endo-dig Cyclization/Halogenation Reactions: Three-Component Synthesis of 1, 3-Disubstituted 4-Haloimidazo[1, 2-a:4, 5-c′]dipyridines

Authors: Enguehard-Gueiffier, Cécile, Delaye, Pierre-Olivier, Pénichon, Mélanie, Denevault-Sabourin, Caroline, Allouchi, Hassan, Gueiffier, Alain

Source: Synthesis. 47(24):3983-3989

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Grignard reagent-promoted 6- endo-dig cyclization: instantaneous synthesis of original dipyrido[1,2- a:3′,4′- d]imidazole

Authors: Oudot, Romain, Costes, Philippe, Allouchi, Hassan, Pouvreau, Mélanie, Abarbri, Mohamed, Gueiffier, Alain, Enguehard-Gueiffier, Cécile

Source: In Tetrahedron 2011 67(49):9576-9581

New flavonoids C-glycosides from Rhabdophyllum arnoldianum

Authors: Ngo Mbing, Joséphine, Missi, Marius Balemaken, Ndongo, Joseph Thierry, ba Njock, Gaetan Bayiha, Atchade, Alex de Théodore, Pegnyemb, Dieudonné Emmanuel, Gueiffier, Alain, Enguehard-Gueiffier, Cécile

Source: Natural product research. 28(8):539-544

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100033085431.0x000001&indx=1&recIds=ETOCvdc_100033085431.0x000001