Large-Scale Multi-Center CT and MRI Segmentation of Pancreas with Deep Learning

Authors: Zhang, Zheyuan, Keles, Elif, Durak, Gorkem, Taktak, Yavuz, Susladkar, Onkar, Gorade, Vandan, Jha, Debesh, Ormeci, Asli C., Medetalibeyoglu, Alpay, Yao, Lanhong, Wang, Bin, Isler, Ilkin Sevgi, Peng, Linkai, Pan, Hongyi, Vendrami, Camila Lopes, Bourhani, Amir, Velichko, Yury, Gong, Boqing, Spampinato, Concetto, Pyrros, Ayis, Tiwari, Pallavi, Klatte, Derk C. F., Engels, Megan, Hoogenboom, Sanne, Bolan, Candice W., Agarunov, Emil, Harfouch, Nassier, Huang, Chenchan, Bruno, Marco J., Schoots, Ivo, Keswani, Rajesh N., Miller, Frank H., Gonda, Tamas, Yazici, Cemal, Tirkes, Temel, Turkbey, Baris, Wallace, Michael B., Bagci, Ulas

Subject Terms: Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition

Access URL: http://arxiv.org/abs/2405.12367

A Critical Appraisal of Data Augmentation Methods for Imaging-Based Medical Diagnosis Applications

Authors: Pattilachan, Tara M., Demir, Ugur, Keles, Elif, Jha, Debesh, Klatte, Derk, Engels, Megan, Hoogenboom, Sanne, Bolan, Candice, Wallace, Michael, Bagci, Ulas

Subject Terms: Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition

Access URL: http://arxiv.org/abs/2301.02181

Neural Transformers for Intraductal Papillary Mucosal Neoplasms (IPMN) Classification in MRI images

Authors: Salanitri, Federica Proietto, Bellitto, Giovanni, Palazzo, Simone, Irmakci, Ismail, Wallace, Michael B., Bolan, Candice W., Engels, Megan, Hoogenboom, Sanne, Aldinucci, Marco, Bagci, Ulas, Giordano, Daniela, Spampinato, Concetto

Subject Terms: Computer Science - Computer Vision and Pattern Recognition, Computer Science - Artificial Intelligence

Access URL: http://arxiv.org/abs/2206.10531

Large-scale multi-center CT and MRI segmentation of pancreas with deep learning

Authors: Zhang, Zheyuan, Keles, Elif, Durak, Gorkem, Taktak, Yavuz, Susladkar, Onkar, Gorade, Vandan, Jha, Debesh, Ormeci, Asli C., Medetalibeyoglu, Alpay, Yao, Lanhong, Wang, Bin, Isler, Ilkin Sevgi, Peng, Linkai, Pan, Hongyi, Vendrami, Camila Lopes, Bourhani, Amir, Velichko, Yury, Gong, Boqing, Spampinato, Concetto, Pyrros, Ayis, Tiwari, Pallavi, Klatte, Derk C.F., Engels, Megan, Hoogenboom, Sanne, Bolan, Candice W., Agarunov, Emil, Harfouch, Nassier, Huang, Chenchan, Bruno, Marco J., Schoots, Ivo, Keswani, Rajesh N., Miller, Frank H., Gonda, Tamas, Yazici, Cemal, Tirkes, Temel, Turkbey, Baris, Wallace, Michael B., Bagci, Ulas

Source: In Medical Image Analysis January 2025 99

Temporal Trends in Body Composition and Metabolic Markers Prior to Diagnosis of Pancreatic Ductal Adenocarcinoma

Authors: Klatte, Derk C.F., Weston, Alexander, Ma, Yaohua, Sledge, Hanna, Bali, Aman, Bolan, Candice, Engels, Megan, van Hooft, Jeanin E., van Leerdam, Monique E., Ouni, Ahmed, Wallace, Michael B., Bi, Yan

Source: In Clinical Gastroenterology and Hepatology September 2024 22(9):1830-1838

Multimodal Pancreatic Cancer Detection Using Methylated DNA Biomarkers in Pancreatic Juice and Plasma CA 19-9: A Prospective Multicenter Study

Authors: Engels, Megan M.L., Berger, Calise K., Mahoney, Douglas W., Hoogenboom, Sanne A., Sarwal, Dhruv, Klatte, Derk C.F., De La Fuente, Jaime, Gandhi, Sonal, Taylor, William R., Foote, Patrick H., Doering, Karen A., Delgado, Adriana M., Burger, Kelli N., Abu Dayyeh, Barham K., Bofill-Garcia, Aliana, Brahmbhatt, Bhaumik, Chandrasekhara, Vinay, Gleeson, Ferga C., Gomez, Victoria, Kumbhari, Vivek, Law, Ryan J., Lukens, Frank J., Raimondo, Massimo, Rajan, Elizabeth, Storm, Andrew C., Vargas Valls, Eric J., van Hooft, Jeanin E., Wallace, Michael B., Kisiel, John B., Majumder, Shounak

Source: In Clinical Gastroenterology and Hepatology

Prospective, Multi-Institutional, Real-Time Next-Generation Sequencing of Pancreatic Cyst Fluid Reveals Diverse Genomic Alterations That Improve the Clinical Management of Pancreatic Cysts

Authors: Paniccia, Alessandro, Polanco, Patricio M., Boone, Brian A., Wald, Abigail I., McGrath, Kevin, Brand, Randall E., Khalid, Asif, Kubiliun, Nisa, O'Broin-Lennon, Anne Marie, Park, Walter G., Klapman, Jason, Tharian, Benjamin, Inamdar, Sumant, Fasanella, Kenneth, Nasr, John, Chennat, Jennifer, Das, Rohit, DeWitt, John, Easler, Jeffrey J., Bick, Benjamin, Singh, Harkirat, Fairley, Kimberly J., Sarkaria, Savreet, Sawas, Tarek, Skef, Wasseem, Slivka, Adam, Tavakkoli, Anna, Thakkar, Shyam, Kim, Victoria, Vanderveldt, Hendrikus Dutch, Richardson, Allyson, Wallace, Michael B., Brahmbhatt, Bhaumik, Engels, Megan, Gabbert, Charles, Dugum, Mohannad, El-Dika, Samer, Bhat, Yasser, Ramrakhiani, Sanjay, Bakis, Gennadiy, Rolshud, Daniil, Millspaugh, Gordon, Tielleman, Thomas, Schmidt, Carl, Mansour, John, Marsh, Wallis, Ongchin, Melanie, Centeno, Barbara, Monaco, Sara E., Ohori, N. Paul, Lajara, Sigfred, Thompson, Elizabeth D., Hruban, Ralph H., Bell, Phoenix D., Smith, Katelyn, Permuth, Jennifer B., Vandenbussche, Christopher, Ernst, Wayne, Grupillo, Maria, Kaya, Cihan, Hogg, Melissa, He, Jin, Wolfgang, Christopher L., Lee, Kenneth K., Zeh, Herbert, Zureikat, Amer, Nikiforova, Marina N., Singhi, Aatur D.

Source: In Gastroenterology January 2023 164(1):117-133

Multimodal Pancreatic Cancer Detection Using Methylated DNA Biomarkers in Pancreatic Juice and Plasma CA 19-9: A Prospective Multicenter Study.

Authors: Engels, Megan M.L., Berger, Calise K., Mahoney, Douglas W., Hoogenboom, Sanne A., Sarwal, Dhruv, Klatte, Derk C.F., De La Fuente, Jaime, Gandhi, Sonal, Taylor, William R., Foote, Patrick H., Doering, Karen A., Delgado, Adriana M., Burger, Kelli N., Abu Dayyeh, Barham K., Bofill-Garcia, Aliana, Brahmbhatt, Bhaumik, Chandrasekhara, Vinay, Gleeson, Ferga C., Gomez, Victoria, Kumbhari, Vivek

Source: Clinical Gastroenterology & Hepatology; Apr2025, Vol. 23 Issue 5, p766-775, 10p

Thrombophlebitis of the Umbilical Vein: A Rare Complication of Acute Pancreatitis.

Authors: Engels, Megan M. L.^1,2 m.m.l.engels@lumc.nl, Spilt, Aart³, Kuijvenhoven, Johan P.¹

Source: Journal of Gastrointestinal & Liver Diseases. Mar2025, Vol. 34 Issue 1, p1-1. 1p.

The additive value of CA19.9 monitoring in a pancreatic cyst surveillance program

Authors: Levink, Iris J. M., Jaarsma, Sanne C., Koopmann, Brechtje D. M., Riet, Priscilla A., Overbeek, Kasper A., Meziani, Jihane, Sprij, Marloes L. J. A., Casadei, Riccardo, Ingaldi, Carlo, Polkowski, Marcin, Engels, Megan M. L., Waaij, Laurens A., Carrara, Silvia, Pando, Elizabeth, Vornhülz, Marlies, Honkoop, Pieter, Schoon, Erik J., Laukkarinen, Johanna, Bergmann, Jilling F., Rossi, Gemma, Vilsteren, Frederike G. I., Berkel, Anne‐Marie, Tabone, Trevor, Schwartz, Matthijs P., Tan, Adriaan C. I. T. L., Hooft, Jeanin E., Quispel, Rutger, Soest, Ellert, Czacko, Laszlo, Bruno, Marco J., Cahen, Djuna L.

Source: United European Gastroenterology Journal; September 2023, Vol. 11 Issue: 7 p601-611, 11p

Prevalence, features, and explanations of missed and misinterpreted pancreatic cancer on imaging: a matched case–control study.

Authors: Hoogenboom, Sanne A.^1,2 s.a.hoogenboom@amsterdamumc.nl, Engels, Megan M. L.^1,3, Chuprin, Anthony V.⁴, van Hooft, Jeanin E.³, LeGout, Jordan D.⁴, Wallace, Michael B.^1,5,6, Bolan, Candice W.⁴

Source: Abdominal Radiology. Dec2022, Vol. 47 Issue 12, p4160-4172. 13p.

Subject Terms: *DISEASE prevalence, *PANCREATIC cancer, *COMPUTED tomography, *MAGNETIC resonance imaging, *ATROPHY

Longitudinal changes in body composition and metabolic markers prior to diagnosis of pancreatic ductal adenocarcinoma

Authors: Klatte, Derk, Weston, Alexander, Engels, Megan, Ouni, Ahmed, Bali, Aman, Ma, Yaohua, van Hooft, Jeanin, van Leerdam, Monique, Ji, Baoan, Carter, Rickey, Bolan, Candice, Wallace, Michael, Bi, Yan

Source: In Pancreatology 5 November 2023 23 Supplement 1:e119-e119

ERCP DISCHARGE TOOL COMBINED WITH RAPID TRYPSINOGEN-2 TEST TO PREDICT SAME-DAY DISCHARGE – A PROSPECTIVE COHORT STUDY

Authors: Sperna Weiland, Christa J., Engels, Megan, Scheffer, Bob, Van Balkom, Bas, van Hee, Koen, Haarhuis, Bertram, Van Hooft, Jeanin, Drenth, Joost, Siersema, Peter, Van Geenen, Erwin-Jan

Source: In Gastrointestinal Endoscopy June 2023 97(6) Supplement:AB669-AB670

Tu1986 A FULLY AUTOMATIC AI SYSTEM FOR PANCREAS SEGMENTATION FROM MULTICENTER MRI SCANS

Authors: Zhang, Zheyuan, Bagci, Ulas, KELES, Elif, Vendrami, Camila Lopes, Jambawalikar, Sachin, Klatte, Derk C., Engels, Megan M., Bolan, Candice W., Agarunov, Emil, Gonda, Tamas A., Keswani, Rajesh N., Miller, Frank, Yazici, Cemal, Wallace, Michael B., Schoots, Ivo, Bruno, Marco J., Tirkes, Temel

Source: In Gastroenterology May 2023 164(6) Supplement:S

1269 PANCREATIC CANCER DETECTION USING METHYLATED DNA MARKERS IN PANCREATIC JUICE: A PROSPECTIVE MULTICENTER VALIDATION STUDY

Authors: Engels, Megan M., Berger, Calise K., Hoogenboom, Sanne A., Sarwal, Dhruv, Klatte, Derk C., De La Fuente, Jaime, Gandhi, Sonal, Taylor, William R., Foote, Patrick H., Doering, Karen, Delgado, Adriana, Burger, Kelli N., Mahoney, Douglas, Dayyeh, Barham K. Abu, Bofill-Garcia, Aliana, brahmbhatt, Bhaumik, Chandrasekhara, Vinay, Gleeson, Ferga C., Gomez, Victoria, Kumbhari, Vivek, Law, Ryan, Levy, Michael J., Lukens, Frank, Raimondo, Massimo, Rajan, Elizabeth, Storm, Andrew C., Vargas, Eric J., Wallace, Michael B., Kisiel, John B., Majumder, Shounak

Source: In Gastroenterology May 2023 164(6) Supplement:S

Increased Use of Prophylactic Measures in Preventing Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis.

Authors: Sperna Weiland, Christina J.^1,2 (AUTHOR), Engels, Megan M. L.² (AUTHOR), Poen, Alexander C.³ (AUTHOR), Bhalla, Abha⁴ (AUTHOR), Venneman, Niels G.⁵ (AUTHOR), van Hooft, Jeanin E.⁶ (AUTHOR), Bruno, Marco J.⁷ (AUTHOR), Verdonk, Robert C.⁸ (AUTHOR), Fockens, Paul⁹ (AUTHOR), Drenth, Joost P. H.¹ (AUTHOR), van Geenen, Erwin J. M.¹ (AUTHOR) Erwin.vangeenen@radboudumc.nl

Source: Digestive Diseases & Sciences. Dec2021, Vol. 66 Issue 12, p4457-4466. 10p.

Subject Terms: *PANCREATIC duct, *CHRONIC pancreatitis, *PANCREATITIS, *ANTI-inflammatory agents, *NONSTEROIDAL anti-inflammatory agents, *INJECTIONS

Geographic Terms: NETHERLANDS

Su1661: BODY COMPOSITION DOES NOT DIFFER BETWEEN PRE-DIAGNOSTIC PANCREATIC DUCTAL ADENOCARCINOMA PATIENTS AND MATCHED CONTROLS ON CT AS DETERMINED BY AUTOMATED SEGMENTATION ALGORITHM: A PILOT STUDY

Authors: Engels, Megan M., Hoogenboom, Sanne A., Klatte, Derk, Chuprin, Anthony, Ouni, Ahmed, Klug, Jason, Korfiatis, Panagiotis, Weston, Alexander D., Hooft, Jeanin E. Van, Wallace, Michael B., Bolan, Candice W., Bi, Yan

Source: In Gastroenterology May 2022 162(7) Supplement:S

541: DEEP LEARNING MODELS IN THE CLASSIFICATION OF INTRADUCTAL PAPILLARY MUCINOUS NEOPLASMS WITH VISUAL EXPLANATION METHODS TO HIGHLIGHT AREAS OF INTEREST FOR ALGORITHM DECISION PROCESS

Authors: Engels, Megan M., Hoogenboom, Sanne, Demir, Ugur, Pattilachan, Tara, Hooft, Jeanin E. Van, Bi, Yan, Bolan, Candice W., Wallace, Michael B., Bagci, Ulas

Source: In Gastroenterology May 2022 162(7) Supplement:S

Pancreatic cyst dilemma: a case where genetic sequencing and immunohistochemistry impacted clinical decision making

Authors: Engels, Megan M.L., Ghoz, Hassan M., Lewis, Jason T., Lewis, Michele D., Wallace, Michael B.

Source: In Gastrointestinal Endoscopy October 2021 94(4):865-866

79 MISSED DIAGNOSIS OF PANCREATIC DUCTAL ADENOCARCINOMA DETECTION USING DEEP CONVOLUTIONAL NEURAL NETWORK

Authors: Hoogenboom, Sanne A., Ravi, Kamalakkannan, Engels, Megan M., Irmakci, Ismail, Keles, Elif, Bolan, Candice W., Wallace, Michael B., Bagci, Ulas

Source: In Gastroenterology May 2021 160(6) Supplement:S