Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming

Authors: Frédérik Oger, Maeva Moreno, Mehdi Derhourhi, Bryan Thiroux, Lionel Berberian, Cyril Bourouh, Emmanuelle Durand, Souhila Amanzougarene, Alaa Badreddine, Etienne Blanc, Olivier Molendi-Coste, Laurent Pineau, Gianni Pasquetti, Laure Rolland, Charlène Carney, Florine Bornaque, Emilie Courty, Céline Gheeraert, Jérôme Eeckhoute, David Dombrowicz, Julie Kerr-Conte, François Pattou, Bart Staels, Philippe Froguel, Amélie Bonnefond, Jean-Sébastien Annicotte

Source: iScience, Vol 26, Iss 7, Pp 107231- (2023)

Subject Terms: Natural sciences, Biological sciences, Molecular biology, Molecular mechanism of gene regulation, Epigenetics, Endocrinology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004223013081; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/75620a5d73cf44908a7169d2d5030f87

Impaired Glucose Homeostasis in a Tau Knock-In Mouse Model

Authors: Hamza Benderradji, Sarra Kraiem, Emilie Courty, Sabiha Eddarkaoui, Cyril Bourouh, Emilie Faivre, Laure Rolland, Emilie Caron, Mélanie Besegher, Frederik Oger, Theo Boschetti, Kévin Carvalho, Bryan Thiroux, Thibaut Gauvrit, Emilie Nicolas, Victoria Gomez-Murcia, Anna Bogdanova, Antonino Bongiovanni, Anne Muhr-Tailleux, Steve Lancel, Kadiombo Bantubungi, Nicolas Sergeant, Jean-Sebastien Annicotte, Luc Buée, Didier Vieau, David Blum, Valérie Buée-Scherrer

Source: Frontiers in Molecular Neuroscience, Vol 15 (2022)

Subject Terms: tau, glucose homeostasis, energy metabolism, mouse model, high-fat, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnmol.2022.841892/full; https://doaj.org/toc/1662-5099

Access URL: https://doaj.org/article/67b740be6a384290b9ac72a4124826f9

Glucose Regulates m6A Methylation of RNA in Pancreatic Islets

Authors: Florine Bornaque, Clément Philippe Delannoy, Emilie Courty, Nabil Rabhi, Charlène Carney, Laure Rolland, Maeva Moreno, Xavier Gromada, Cyril Bourouh, Pauline Petit, Emmanuelle Durand, François Pattou, Julie Kerr-Conte, Philippe Froguel, Amélie Bonnefond, Frédérik Oger, Jean-Sébastien Annicotte

Source: Cells, Vol 11, Iss 2, p 291 (2022)

Subject Terms: epitranscriptome, insulin secretion, pancreatic beta cell, type 2 diabetes, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/2/291; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/6966ecd7b0ea46b7922fa05d22b50b8e