Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target

Authors: Li, Yedda, Xu, Yue, Benitez, Bruno A., Nagree, Murtaza S., Dearborn, Joshua T., Jiang, Xuntian, Guzman, Miguel A., Woloszynek, Josh C., Giaramita, Alex, Yip, Bryan K., Elsbernd, Joseph, Babcock, Michael C., Lo, Melanie, Fowler, Stephen C., Wozniak, David F., Vogler, Carole A., Medin, Jeffrey A., Crawford, Brett E., Sands, Mark S.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Oct 01. 116(40), 20097-20103.

Access URL: https://www.jstor.org/stable/26857092

Genetic ablation of acid ceramidase in Krabbe disease confirms the psychosine hypothesis and identifies a new therapeutic target.

Authors: Yedda Li, Yue Xu, Benitez, Bruno A., Nagree, Murtaza S., Dearborn, Joshua T., Xuntian Jiang, Guzman, Miguel A., Woloszynek, Josh C., Giaramita, Alex, Yip, Bryan K., Elsbernd, Joseph, Babcock, Michael C., Lo, Melanie, Fowler, Stephen C., Wozniak, David F., Vogler, Carole A., Medin, Jeffrey A., Crawford, Brett E., Sands, Mark S.

Source: Proceedings of the National Academy of Sciences of the United States of America; Oct2019, Vol. 116 Issue 40, p20097-20103, 7p

Subject Terms: ENZYME deficiency, LIFE spans, HYPOTHESIS, DEACYLATION, DISEASES