Addressing the pathophysiology of venous thrombosis and chronic kidney disease in sickle cell trait using a mouse model

Authors: Trebak, Fatima ¹, Sako, Mohammad O. ², Grover, Steven P. ¹, Seanoon, Karnsasin ¹, Pawlinski, Izabela ¹, Moonla, Chatphatai ¹, Henderson, Michael W. ¹, Derebail, Vimal K. ³, Monroe, Dougald M. ¹, Ellsworth, Patrick ¹, Pawlinski, Rafal ¹, Kasztan, Malgorzata ^{2, ∗}, Key, Nigel S. ^{1, ∗∗}

Source: In Blood Advances February 2025

Real-world impact of emicizumab and immunosuppression on acquired hemophilia A: a multicenter US cohort

Authors: Poston, Jacqueline N., Bryan, Cassandra, von Drygalski, Annette, Al Banaa, Kadhim, Zhou, Jenny Y., Parnes, Aric, Chen, Evan C., Khan, Osman, Ellsworth, Patrick, Cafuir, Lorraine, Walsh, Christopher, Escobar, Miguel A., Wu, James F., Malec, Lynn M., Kessler, Craig M., Janbain, Maissaa, Kruse-Jarres, Rebecca

Source: In Blood Advances 26 November 2024 8(22):5896-5905

Emicizumab promotes factor Xa generation on endothelial cells

Authors: Fager, Ammon M., Ellsworth, Patrick, Key, Nigel S., Monroe, Dougald M., Hoffman, Maureane

Source: In Journal of Thrombosis and Haemostasis June 2024 22(6):1605-1615

Leaf cell wall properties and stomatal density influence oxygen isotope enrichment of leaf water

Authors: Ellsworth, Patrick Z., Ellsworth, Patrícia V., Mertz, Rachel A., Koteyeva, Nuria K., Cousins, Asaph B.

Source: Plant, cell and environment. 46(9):2694-2710

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100189989487.0x000001&indx=1&recIds=ETOCvdc_100189989487.0x000001

Indicators of water use efficiency across diverse agroecosystems and spatiotemporal scales

Authors: Hoover, David L., Abendroth, Lori J., Browning, Dawn M., Saha, Amartya, Snyder, Keirith, Wagle, Pradeep, Witthaus, Lindsey, Baffaut, Claire, Biederman, Joel A., Bosch, David D., Bracho, Rosvel, Busch, Dennis, Clark, Patrick, Ellsworth, Patrick, Fay, Philip A., Flerchinger, Gerald, Kearney, Sean, Levers, Lucia, Saliendra, Nicanor, Schmer, Marty, Schomberg, Harry, Scott, Russell L.

Source: In Science of the Total Environment 15 March 2023 864

Pan-cancer prediction of radiotherapy benefit using genomic-adjusted radiation dose (GARD): a cohort-based pooled analysis

Authors: Scott, Jacob G, Sedor, Geoffrey, Ellsworth, Patrick, Scarborough, Jessica A, Ahmed, Kamran A, Oliver, Daniel E, Eschrich, Steven A, Kattan, Michael W, Torres-Roca, Javier F ^*

Source: In The Lancet Oncology September 2021 22(9):1221-1229

Acquired hemophilia A: a narrative review and management approach in the emicizumab era

Authors: Ellsworth, Patrick, Chen, Sheh-Li, Jones, Lee Ann, Ma, Alice D., Key, Nigel S.

Source: Journal of Thrombosis and Haemostasis; March 2025, Vol. 23 Issue: 3 p824-835, 12p

Emicizumab reduces re‐hospitalization for bleeding in acquired haemophilia A

Authors: Chen, Sheh‐Li, Ellsworth, Patrick, Kasthuri, Raj S., Moll, Stephan, Ma, Alice D., Key, Nigel S.

Source: Haemophilia. 27(4):e585-e588

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128326088.0x000001&indx=1&recIds=ETOCvdc_100128326088.0x000001

Recombinant porcine factor VIII use in bleed treatment in non‐severe haemophilia A inhibitor patients: Dosing strategies and efficacy

Authors: Ellsworth, Patrick, Chen, Sheh‐Li, Key, Nigel, Abajas, Yasmina, Ma, Alice

Source: Haemophilia. 27(1):e147-e150

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121161917.0x000001&indx=1&recIds=ETOCvdc_100121161917.0x000001

A comprehensive epidemiological review of spinal astrocytomas in the United States

Authors: Shao, Jianning, Jones, Jaes, Ellsworth, Patrick, Habboub, Ghaith, Cioffi, Gino, Patil, Nirav, Ostrom, Quinn T., Kruchko, Carol, Barnholtz-Sloan, Jill S., Kshettry, Varun R.

Source: Journal of neurosurgery.Spine. 34(2):303-309

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625512917&indx=1&recIds=ETOCRN625512917

Carbon Isotopic Composition Reflects Intrinsic Water Use Efficiency But Not its Component Traits in Sugarcane.

Authors: Ellsworth, Patrick Z., White Jr., Paul M.

Source: Tropical Plant Biology; Dec2024, Vol. 17 Issue 4, p306-315, 10p

Hypertonicity and/or acidosis induce marked rheological changes under hypoxic conditions in sickle trait red blood cells.

Authors: Ellsworth, Patrick^1,2 (AUTHOR), Pawlinski, Izabela J.¹ (AUTHOR), Sielaty, Rachel¹ (AUTHOR), Ilich, Anton¹ (AUTHOR), Prokopenko, Yuriy¹ (AUTHOR), Moonla, Chatphatai^1,3 (AUTHOR), Monroe, Dougald M.^1,2 (AUTHOR), Pawlinski, Rafal^1,2 (AUTHOR), Key, Nigel S.^1,2 (AUTHOR) nigel_key@med.unc.edu

Source: British Journal of Haematology. Oct2024, Vol. 205 Issue 4, p1565-1569. 5p.

Subject Terms: *SICKLE cell trait, *ERYTHROCYTES, *ACIDOSIS, *RHEOLOGY, *OSMOLALITY

Recombinant porcine FVIII for bleed treatment in acquired hemophilia A: findings from a single-center, 18-patient cohort

Authors: Ellsworth, Patrick, Chen, Sheh-Li, Kasthuri, Raj S., Key, Nigel S., Mooberry, Micah J., Ma, Alice D.

Source: In Blood Advances 22 December 2020 4(24):6240-6249

Raise the roof, build the floor

Authors: Pecker, Lydia H., Ellsworth, Patrick

Source: Blood. 140(13):1453-1455

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183254680.0x000001&indx=1&recIds=ETOCvdc_100183254680.0x000001

Linking soil nutrient availability, fine root production and turnover, and species composition in a seasonally dry plant community

Authors: Ellsworth, Patrick Z., Sternberg, Leonel S. L.

Source: Plant and Soil, 2019 Sep 01. 442(1/2), 49-63.

Access URL: https://www.jstor.org/stable/48704009

Research Letter: Patient Attitudes Towards Haemophilia Gene Therapy at a US Haemophilia Treatment Center.

Authors: Berkowitz, Callie, Lee, Kristy, Kirkland, Kristi, Nielsen, Brenda, Ellsworth, Patrick, Ma, Alice, Key, Nigel S.

Source: Haemophilia; Jan2025, Vol. 31 Issue 1, p166-168, 3p

Subject Terms: HEMOPHILIA, GENE therapy, HEALTH facilities, COST, PATIENTS' attitudes, TREATMENT effectiveness, DRUG side effects, QUESTIONNAIRES

Geographic Terms: UNITED States

Red blood cell microvesicles activate the contact system, leading to factor IX activation via 2 independent pathways

Authors: Noubouossie, Denis F. ^{1, 2}, Henderson, Michael W. ^{2, 3}, Mooberry, Micah ^{1, 2}, Ilich, Anton ^{1, 2}, Ellsworth, Patrick ^{1, 3}, Piegore, Mark ^{1, 2}, Skinner, Sarah C. ^{1, 2, 3}, Pawlinski, Rafal ^{1, 2}, Welsby, Ian ⁴, Renné, Thomas ⁵, Hoffman, Maureane ⁶, Monroe, Dougald M. ^{1, 2}, Key, Nigel S. ^{1, 1, 2, 3}

Source: In Blood 5 March 2020 135(10):755-765

Development and application of global assays of hyper‐ and hypofibrinolysis

Authors: Ilich, Anton, Noubouossie, Denis F., Henderson, Michael, Ellsworth, Patrick, Molitor, Kathleen F., Campello, Elena, Meeks, Shannon, Dunn, Amy, Park, Myung S., Pawlinski, Rafal, Simioni, Paolo, Shapiro, Amy, Key, Nigel S. ^*

Source: In Research and Practice in Thrombosis and Haemostasis January 2020 4(1):46-53

Red blood cells modulate structure and dynamics of venous clot formation in sickle cell disease

Authors: Faes, Camille, Ilich, Anton, Sotiaux, Amandine, Sparkenbaugh, Erica M., Henderson, Michael W., Buczek, Laura, Beckman, Joan D., Ellsworth, Patrick, Noubouossie, Denis F., Bhoopat, Lantarima, Piegore, Mark, Renoux, Céline, Bergmeier, Wolfgang, Park, Yara, Ataga, Kenneth I., Cooley, Brian, Wolberg, Alisa S., Key, Nigel S., Pawlinski, Rafal ^*

Source: In Blood 6 June 2019 133(23):2529-2541

Pregnancy in sickle cell trait: what we do and don't know

Authors: Wilson, Samuel, Ellsworth, Patrick, Key, Nigel S.

Source: British journal of haematology. 190(3):328-335

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122574158.0x000001&indx=1&recIds=ETOCvdc_100122574158.0x000001