Deep Learning vs Traditional Breast Cancer Risk Models to Support Risk-Based Mammography Screening

Authors: Lehman, Constance D, Mercaldo, Sarah, Lamb, Leslie R, King, Tari A, Ellisen, Leif W, Specht, Michelle, Tamimi, Rulla M

Source: Journal of the National Cancer Institute. 114(10):1355-1363

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Dynamic HER2-low status among patients with triple negative breast cancer (TNBC) and the impact of repeat biopsies.

Authors: Bar, Yael, Fell, Geoffrey, Dedeoglu, Aylin, Moffett, Natalie, Vidula, Neelima, Spring, Laura, Wander, Seth A., Bardia, Aditya, Ko, Naomi, Moy, Beverly, Ellisen, Leif W., Isakoff, Steven J.

Source: NPJ Breast Cancer; 3/11/2025, Vol. 11 Issue 1, p1-8, 8p

Locally Recurrent Secretory Carcinoma of the Breast with NTRK3 Gene Fusion

Authors: Mortensen, Lindsey, Ordulu, Zehra, Dagogo‐Jack, Ibiayi, Bossuyt, Veerle, Winters, Loren, Taghian, Alphonse, Smith, Barbara L., Ellisen, Leif W., Kiedrowski, Lesli A., Lennerz, Jochen K., Bardia, Aditya, Spring, Laura M.

Source: Oncologist. 26(10):818-824

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Novel Agents for Metastatic Triple-Negative Breast Cancer: Finding the Positive in the Negative

Authors: Vidula, Neelima, Ellisen, Leif W., Bardia, Aditya

Source: Journal of the National Comprehensive Cancer Network. 19(1):109-117

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Targeting TAp63 in Breast Cancer

Authors: Ellisen, Leif W.

Source: Oncology. 35(6):368-371

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Loss of p53 and genetic evolution in pancreatic cancer: Ordered chaos after the guardian is gone

Authors: Wu, Bogang, Ellisen, Leif W.

Source: Cancer cell. 40(11):1276-1278

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Exploring the "chemo" in chemoimmunotherapy for triple-negative breast cancer.

Authors: Liu, Ting^1,2 (AUTHOR), Ellisen, Leif W.^1,2,3 (AUTHOR) lellisen@mgh.harvard.edu

Source: Cancer Cell. Mar2025, Vol. 43 Issue 3, p332-334. 3p.

Subject Terms: *TRIPLE-negative breast cancer, *MAST cells, *RNA sequencing, *CELL aggregation, *CANCER cells

Immune activation and evolution through chemotherapy plus checkpoint blockade in triple-negative breast cancer

Authors: Koh, Siang-Boon, Ellisen, Leif W.

Source: Cancer cell. 39(12):1562-1564

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154740834.0x000001&indx=1&recIds=ETOCvdc_100154740834.0x000001

Optimizing Access to Liquid Biopsy in the Present and Future Cancer Landscape.

Authors: Medford, Arielle J.^1,2,3 (AUTHOR), Ellisen, Leif W.^1,2,4 (AUTHOR) lellisen@mgh.harvard.edu

Source: JCO Precision Oncology. 12/1/2024, Vol. 8, p1-3. 3p.

Subject Terms: *BIOPSY, *LIQUIDS, *ONCOLOGY, *MANUSCRIPTS

Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity

Authors: Tata, Purushothama Rao, Chow, Ryan D., Saladi, Srinivas Vinod, Tata, Aleksandra, Konkimalla, Arvind, Bara, Anne, Montoro, Daniel, Hariri, Lida P., Shih, Angela R., Mino-Kenudson, Mari, Mou, Hongmei, Kimura, Shioko, Ellisen, Leif W., Rajagopal, Jayaraj

Source: In Developmental Cell 26 March 2018 44(6):679-693

Case–control analysis identifies shared properties of rare germline variation in cancer predisposing genes

Authors: Artomov, Mykyta, Joseph, Vijai, Tiao, Grace, Thomas, Tinu, Schrader, Kasmintan, Klein, Robert, Kiezun, Adam, Gupta, Namrata, Margolin, Lauren, Stratigos, Alexander, Kim, Ivana, Shannon, Kristen, Ellisen, Leif, Haber, Daniel, Getz, Gad, Tsao, Hensin, Lipkin, Steven, Altshuler, David, Offit, Kenneth, Daly, Mark

Source: European journal of human genetics. 27(5):824-828

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PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Authors: Tanaka, Shota, Batchelor, Tracy, Iafrate, A., Dias-Santagata, Dora, Borger, Darrell, Ellisen, Leif, Yang, Daniel, Louis, David, Cahill, Daniel, Chi, Andrew

Source: Acta neuropathologica communications. 7(1):1-8

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Blood-based monitoring identifies acquired and targetable driver HER2 mutations in endocrine-resistant metastatic breast cancer

Authors: Medford, Arielle, Dubash, Taronish, Juric, Dejan, Spring, Laura, Niemierko, Andrzej, Vidula, Neelima, Peppercorn, Jeffrey, Isakoff, Steven, Reeves, Brittany, LiCausi, Joseph, Wesley, Benjamin, Malvarosa, Giuliana, Yuen, Megan, Wittner, Ben, Lawrence, Michael, Iafrate, A., Ellisen, Leif, Moy, Beverly, Toner, Mehmet, Maheswaran, Shyamala, Haber, Daniel, Bardia, Aditya

Source: Npj precision oncology. 3(1):1-9

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Women's Health Issues for BRCA Mutation Carriers
American society of clinical oncology (Annual meeting)

Authors: Sabatini, Mary E., Ellisen, Leif W.

Source: American Society of Clinical Oncology .... educational book. 52:14-17

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Genomic spectrum of actionable alterations in serial cell free DNA (cfDNA) analysis of patients with metastatic breast cancer.

Authors: Bar, Yael, Keenan, Jennifer C., Niemierko, Andrzej, Medford, Arielle J., Isakoff, Steven J., Ellisen, Leif W., Bardia, Aditya, Vidula, Neelima

Source: NPJ Breast Cancer; 4/11/2024, Vol. 10 Issue 1, p1-10, 10p

ACTL6A Is Co-Amplified with p63 in Squamous Cell Carcinoma to Drive YAP Activation, Regenerative Proliferation, and Poor Prognosis

Authors: Saladi, Srinivas Vinod, Ross, Kenneth, Karaayvaz, Mihriban, Tata, Purushothama R., Mou, Hongmei, Rajagopal, Jayaraj, Ramaswamy, Sridhar, Ellisen, Leif W.

Source: In Cancer Cell 9 January 2017 31(1):35-49

Complete Remission Following Pembrolizumab in a Woman with Mismatch Repair‐Deficient Endometrial Cancer and a Germline BRCA1 Mutation

Authors: Dizon, Don S., Dias‐Santagata, Dora, Bregar, Amy, Sullivan, Laura, Filipi, Jennifer, DiTavi, Elizabeth, Miller, Lucy, Ellisen, Leif, Birrer, Michael, DelCarmen, Marcela

Source: Oncologist. 23(6):650-653

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Unravelling subclonal heterogeneity and aggressive disease states in TNBC through single-cell RNA-seq

Authors: Karaayvaz, Mihriban, Cristea, Simona, Gillespie, Shawn, Patel, Anoop, Mylvaganam, Ravindra, Luo, Christina, Specht, Michelle, Bernstein, Bradley, Michor, Franziska, Ellisen, Leif

Source: Nature communications. 9(1):1-10

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A Systematic Comparison of Traditional and Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Genes in More Than 1000 Patients

Authors: Lincoln, Stephen E., Kobayashi, Yuya, Anderson, Michael J., Yang, Shan, Desmond, Andrea J., Mills, Meredith A., Nilsen, Geoffrey B., Jacobs, Kevin B., Monzon, Federico A., Kurian, Allison W., Ford, James M., Ellisen, Leif W.

Source: In The Journal of Molecular Diagnostics September 2015 17(5):533-544

A wound-healing program is hijacked to promote cancer metastasis

Authors: Ellisen, Leif W.

Source: Journal of experimental medicine. 214(10):2813-2816

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN613079992&indx=1&recIds=ETOCRN613079992