The association between genetically elevated polyunsaturated fatty acids and risk of cancer

Authors: Tintle, Nathan, Rice, Terri, Cheng, Iona, Jenkins, Mark, Gallinger, Steve, Cornish, Alex J., Sud, Amit, Vijayakrishnan, Jayaram, Wrensch, Margaret, Johansson, Mattias, Norman, Aaron D., Klein, Alison, Clay-Gilmour, Alyssa, Franke, Andre, Ardisson Korat, Andres V., Wheeler, Bill, Nilsson, Björn, Smith, Caren, Heng, Chew-Kiat, Song, Ci, Riadi, David, Claus, Elizabeth B., Ellinghaus, Eva, Ostroumova, Evgenia, Hosnijeh, de Vathaire, Florent, Cugliari, Giovanni, Matullo, Giuseppe, Oi-Lin Ng, Irene, Passow, Jeanette E., Foo, Jia Nee, Han, Jiali, Liu, Jianjun, Barnholtz-Sloan, Jill, Schildkraut, Joellen M., Maris, John, Wiemels, Joseph L., Hemminki, Kari, Yang, Keming, Kiemeney, Lambertus A., Wu, Lang, Amundadottir, Laufey, Stern, Marc-Henri, Boutron, Marie-Christine, Iles, Mark Martin, Purdue, Mark P., Stanulla, Martin, Bondy, Melissa, Gaudet, Mia, Mobuchon, Lenha, Camp, Nicola J., Sham, Pak Chung, Guénel, Pascal, Brennan, Paul, Taylor, Philip R., Ostrom, Quinn, Stolzenberg-Solomon, Rachael, Dorajoo, Rajkumar, Houlston, Richard, Jenkins, Robert B., Diskin, Sharon, Berndt, Sonja I., Tsavachidis, Spiridon, Channock, Stephen J., Harrison, Tabitha, Galesloot, Tessel, Gyllensten, Ulf, Joseph, Vijai, Shi, Y., Yang, Wenjian, Lin, Yi, Van Den Eeden, Stephen K., Haycock, Philip C., Borges, Maria Carolina, Burrows, Kimberley, Lemaitre, Rozenn N., Burgess, Stephen, Khankari, Nikhil K., Tsilidis, Konstantinos K., Gaunt, Tom R., Hemani, Gibran, Zheng, Jie, Truong, Therese, Birmann, Brenda M., OMara, Tracy, Spurdle, Amanda B., Iles, Mark M., Law, Matthew H., Slager, Susan L., Saberi Hosnijeh, Fatemeh, Mariosa, Daniela, Cotterchio, Michelle, Cerhan, James R., Peters, Ulrike, Enroth, Stefan, Gharahkhani, Puya, Le Marchand, Loic, Williams, Ann C., Block, Robert C., Amos, Christopher I., Hung, Rayjean J., Zheng, Wei, Gunter, Marc J., Smith, George Davey, Relton, Caroline, Martin, Richard M.

Source: In eBioMedicine May 2023 91

Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations

Authors: Degenhardt, Frauke, Mayr, Gabriele, Wendorff, Mareike, Boucher, Gabrielle, Ellinghaus, Eva, Ellinghaus, David, ElAbd, Hesham, Rosati, Elisa, Hübenthal, Matthias, Juzenas, Simonas, Abedian, Shifteh, Vahedi, Homayon, Thelma, B K, Yang, Suk-Kyun, Ye, Byong Duk, Cheon, Jae Hee, Datta, Lisa Wu, Daryani, Naser Ebrahim, Ellul, Pierre, Esaki, Motohiro, Fuyuno, Yuta, McGovern, Dermot P B, Haritunians, Talin, Hong, Myhunghee, Juyal, Garima, Jung, Eun Suk, Kubo, Michiaki, Kugathasan, Subra, Lenz, Tobias L, Leslie, Stephen, Malekzadeh, Reza, Midha, Vandana, Motyer, Allan, Ng, Siew C, Okou, David T, Raychaudhuri, Soumya, Schembri, John, Schreiber, Stefan, Song, Kyuyoung, Sood, Ajit, Takahashi, Atsushi, Torres, Esther A, Umeno, Junji, Alizadeh, Behrooz Z, Weersma, Rinse K, Wong, Sunny H, Yamazaki, Keiko, Karlsen, Tom H, Rioux, John D, Brant, Steven R, Franke, Andre

Source: Human molecular genetics. 30(5):356-369

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121120138.0x000001&indx=1&recIds=ETOCvdc_100121120138.0x000001

Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expression

Authors: Mucha, Sören, Baurecht, Hansjörg, Novak, Natalija, Rodríguez, Elke, Bej, Saptarshi, Mayr, Gabriele, Emmert, Hila, Stölzl, Dora, Gerdes, Sascha, Jung, Eun Suk, Degenhardt, Frauke, Hübenthal, Matthias, Ellinghaus, Eva, Kässens, Jan Christian, Wienbrandt, Lars, Lieb, Wolfgang, Müller-Nurasyid, Martina, Hotze, Melanie, Dand, Nick, Grosche, Sarah, Marenholz, Ingo, Arnold, Andreas, Homuth, Georg, Schmidt, Carsten O., Wehkamp, Ulrike, Nöthen, Markus M., Hoffmann, Per, Paternoster, Lavinia, Standl, Marie, Bønnelykke, Klaus, Ahluwalia, Tarunveer S., Bisgaard, Hans, Peters, Annette, Gieger, Christian, Waldenberger, Melanie, Schulz, Holger, Strauch, Konstantin, Werfel, Thomas, Lee, Young-Ae, Wolfien, Markus, Rosenstiel, Philip, Wolkenhauer, Olaf, Schreiber, Stefan, Franke, Andre, Weidinger, Stephan, Ellinghaus, David

Source: In The Journal of Allergy and Clinical Immunology April 2020 145(4):1208-1218

Epidermal lipid composition, barrier integrity, and eczematous inflammation are associated with skin microbiome configuration

Authors: Baurecht, Hansjörg ^∗, Rühlemann, Malte C. ^∗, Rodríguez, Elke, Thielking, Frederieke, Harder, Inken, Erkens, Anna-Sophie, Stölzl, Dora, Ellinghaus, Eva, Hotze, Melanie, Lieb, Wolfgang, Wang, Sheng, Heinsen-Groth, Femke-Anouska, Franke, Andre, Weidinger, Stephan

Source: In The Journal of Allergy and Clinical Immunology May 2018 141(5):1668-1676

Genome‐wide association study of psoriasis in an Egyptian population

Authors: Bejaoui, Yosra, Witte, Mareike, Abdelhady, Mohamed, Eldarouti, Mohammad, Abdallah, Nermeen M. A., Elghzaly, Ashraf Antar, Tawhid, Ziyad, Gaballah, Mohammad Ali, Busch, Hauke, Munz, Matthias, Wendorff, Mareike, Ellinghaus, Eva, Franke, Andre, Ibrahim, Saleh M.

Source: Experimental dermatology. 28(5):623-627

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083709471.0x000001&indx=1&recIds=ETOCvdc_100083709471.0x000001

Genetic association with B-cell acute lymphoblastic leukemia in allogeneic transplant patients differs by age and sex

Authors: Clay-Gilmour, Alyssa I. ¹, Hahn, Theresa ², Preus, Leah M. ³, Onel, Kenan ⁴, Skol, Andrew ⁵, Hungate, Eric ⁵, Zhu, Qianqian ⁶, Haiman, Christopher A. ⁷, Stram, Daniel O. ⁷, Pooler, Loreall ⁷, Sheng, Xin ⁷, Yan, Li ⁶, Liu, Qian ⁸, Hu, Qiang ⁶, Liu, Song ⁶, Battaglia, Sebastiano ⁹, Zhu, Xiaochun ¹⁰, Block, AnneMarie W. ¹¹, Sait, Sheila N.J. ¹¹, Karaesmen, Ezgi ³, Rizvi, Abbas ³, Weisdorf, Daniel J. ¹², Ambrosone, Christine B. ¹³, Tritchler, David ⁸, Ellinghaus, Eva ¹⁴, Ellinghaus, David ¹⁴, Stanulla, Martin ¹⁵, Clavel, Jacqueline ^{16, 17}, Orsi, Laurent ^{16, 17}, Spellman, Stephen ¹⁸, Pasquini, Marcelo C. ¹⁰, McCarthy, Philip L. ², Sucheston-Campbell, Lara E. ^{3, 19}

Source: In Blood Advances 12 September 2017 1(20):1717-1728

Predicting Humoral Alloimmunity from Differences in Donor and Recipient HLA Surface Electrostatic Potential

Authors: Mallon, Dermot H., Kling, Christiane, Robb, Matthew, Ellinghaus, Eva, Bradley, J. Andrew, Taylor, Craig J., Kabelitz, Dieter, Kosmoliaptsis, Vasilis

Source: Journal of immunology. 201(12):3780-3792

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN618442352&indx=1&recIds=ETOCRN618442352

Genetic and transcriptional analysis of inflammatory bowel disease-associated pathways in patients with GUCY2C-linked familial diarrhea

Authors: Tronstad, Rune R., Polushina, Tatiana, Brattbakk, Hans-Richard, Stansberg, Christine, von Volkmann, Hilde Løland, Hanevik, Kurt, Ellinghaus, Eva, Jørgensen, Silje Fjellgård, Ersland, Kari Merete, Pham, Khanh D.-C., Gilja, Odd Helge, Hovdenak, Nils, Hausken, Trygve, Vatn, Morten H., Franke, Andre, Knappskog, Per Morten, Le Hellard, Stephanie, Karlsen, Tom Hemming, Fiskerstrand, Torunn

Source: Scandinavian journal of gastroenterology. 53(10-11):1264-1273

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100104128082.0x000001&indx=1&recIds=ETOCvdc_100104128082.0x000001

Nonsyndromic cleft lip with or without cleft palate and cancer: Evaluation of a possible common genetic background through the analysis of GWAS data

Authors: Dunkhase, Eva, Ludwig, Kerstin U., Knapp, Michael, Skibola, Christine F., Figueiredo, Jane C., Hosking, Fay Julie, Ellinghaus, Eva, Landi, Maria Teresa, Ma, Hongxia, Nakagawa, Hidewaki, Kim, Jong-Won, Han, Jiali, Yang, Ping, Böhmer, Anne C., Mattheisen, Manuel, Nöthen, Markus M., Mangold, Elisabeth

Source: In Genomics Data December 2016 10:22-29

Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture

Authors: Stuart, Philip E., Nair, Rajan P., Tsoi, Lam C., Tejasvi, Trilokraj, Das, Sayantan, Kang, Hyun Min, Ellinghaus, Eva, Chandran, Vinod, Callis-Duffin, Kristina, Ike, Robert, Li, Yanming, Wen, Xiaoquan, Enerbäck, Charlotta, Gudjonsson, Johann E., Kõks, Sulev, Kingo, Külli, Esko, Tõnu, Mrowietz, Ulrich, Reis, Andre, Wichmann, H. Erich, Gieger, Christian, Hoffmann, Per, Nöthen, Markus M., Winkelmann, Juliane, Kunz, Manfred, Moreta, Elvia G., Mease, Philip J., Ritchlin, Christopher T., Bowcock, Anne M., Krueger, Gerald G., Lim, Henry W., Weidinger, Stephan, Weichenthal, Michael, Voorhees, John J., Rahman, Proton, Gregersen, Peter K., Franke, Andre, Gladman, Dafna D., Abecasis, Gonçalo R., Elder, James T.

Source: In The American Journal of Human Genetics 3 December 2015 97(6):816-836

Imputation of KIR Types from SNP Variation Data

Authors: Vukcevic, Damjan, Traherne, James A., Næss, Sigrid, Ellinghaus, Eva, Kamatani, Yoichiro, Dilthey, Alexander, Lathrop, Mark, Karlsen, Tom H., Franke, Andre, Moffatt, Miriam, Cookson, William, Trowsdale, John, McVean, Gil, Sawcer, Stephen, Leslie, Stephen

Source: In The American Journal of Human Genetics 1 October 2015 97(4):593-607

Exome-wide association study reveals novel psoriasis susceptibility locus at TNFSF15 and rare protective alleles in genes contributing to type I IFN signalling

Authors: Dand, Nick, Mucha, Sören, Tsoi, Lam C, Mahil, Satveer K, Stuart, Philip E, Arnold, Andreas, Baurecht, Hansjörg, Burden, A David, Callis Duffin, Kristina, Chandran, Vinod, Curtis, Charles J, Das, Sayantan, Ellinghaus, David, Ellinghaus, Eva, Enerback, Charlotta, Esko, Tõnu, Gladman, Dafna D, Griffiths, Christopher E M, Gudjonsson, Johann E, Hoffman, Per, Homuth, Georg, Hüffmeier, Ulrike, Krueger, Gerald G, Laudes, Matthias, Lee, Sang Hyuck, Lieb, Wolfgang, Lim, Henry W, Löhr, Sabine, Mrowietz, Ulrich, Müller-Nurayid, Martina, Nöthen, Markus, Peters, Annette, Rahman, Proton, Reis, André, Reynolds, Nick J, Rodriguez, Elke, Schmidt, Carsten O, Spain, Sarah L, Strauch, Konstantin, Tejasvi, Trilokraj, Voorhees, John J, Warren, Richard B, Weichenthal, Michael, Weidinger, Stephan, Zawistowski, Matthew, Nair, Rajan P, Capon, Francesca, Smith, Catherine H, Trembath, Richard C, Abecasis, Goncalo R, Elder, James T, Franke, Andre, Simpson, Michael A, Barker, Jonathan N

Source: Human molecular genetics. 26(21):4301-4313

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100074715008.0x000001&indx=1&recIds=ETOCvdc_100074715008.0x000001

Genome-wide Comparative Analysis of Atopic Dermatitis and Psoriasis Gives Insight into Opposing Genetic Mechanisms

Authors: Baurecht, Hansjörg, Hotze, Melanie, Brand, Stephan, Büning, Carsten, Cormican, Paul, Corvin, Aiden, Ellinghaus, David, Ellinghaus, Eva, Esparza-Gordillo, Jorge, Fölster-Holst, Regina, Franke, Andre, Gieger, Christian, Hubner, Norbert, Illig, Thomas, Irvine, Alan D., Kabesch, Michael, Lee, Young A.E., Lieb, Wolfgang, Marenholz, Ingo, McLean, W.H. Irwin, Morris, Derek W., Mrowietz, Ulrich, Nair, Rajan, Nöthen, Markus M., Novak, Natalija, O’Regan, Grainne M., Schreiber, Stefan, Smith, Catherine, Strauch, Konstantin, Stuart, Philip E., Trembath, Richard, Tsoi, Lam C., Weichenthal, Michael, Barker, Jonathan, Elder, James T., Weidinger, Stephan, Cordell, Heather J., Brown, Sara J.

Source: In The American Journal of Human Genetics 8 January 2015 96(1):104-120

Fine Mapping Major Histocompatibility Complex Associations in Psoriasis and Its Clinical Subtypes

Authors: Okada, Yukinori, Han, Buhm, Tsoi, Lam C., Stuart, Philip E., Ellinghaus, Eva, Tejasvi, Trilokraj, Chandran, Vinod, Pellett, Fawnda, Pollock, Remy, Bowcock, Anne M., Krueger, Gerald G., Weichenthal, Michael, Voorhees, John J., Rahman, Proton, Gregersen, Peter K., Franke, Andre, Nair, Rajan P., Abecasis, Gonçalo R., Gladman, Dafna D., Elder, James T., de Bakker, Paul I.W., Raychaudhuri, Soumya

Source: In The American Journal of Human Genetics 7 August 2014 95(2):162-172

Reduced FOXP3+ regulatory T cells in patients with primary sclerosing cholangitis are associated with IL2RA gene polymorphisms

Authors: Sebode, Marcial, Peiseler, Moritz, Franke, Björn, Schwinge, Dorothee, Schoknecht, Tanja, Wortmann, Frederike, Quaas, Alexander, Petersen, Britt-Sabina, Ellinghaus, Eva, Baron, Udo, Olek, Sven, Wiegard, Christiane, Weiler-Normann, Christina, Lohse, Ansgar W., Herkel, Johannes, Schramm, Christoph

Source: In Journal of Hepatology May 2014 60(5):1010-1016

HLA-DPA1*02:01~B1*01:01is a risk haplotype for primary sclerosing cholangitis mediating activation of NKp44+ NK cells

Authors: Zecher, Britta F, Ellinghaus, David, Schloer, Sebastian, Niehrs, Annika, Padoan, Benedetta, Baumdick, Martin E, Yuki, Yuko, Martin, Maureen P, Glow, Dawid, Schro¨der-Schwarz, Jennifer, Niersch, Jennifer, Brias, Sébastien, Mu¨ller, Luisa M, Habermann, Robin, Kretschmer, Paul, Fru¨h, Tristan, Da¨nekas, Janis, Wehmeyer, Malte H, Poch, Tobias, Sebode, Marcial, Ellinghaus, Eva, Degenhardt, Frauke, Ko¨rner, Christian, Hoelzemer, Angelique, Fehse, Boris, Oldhafer, Karl J, Schumacher, Udo, Sauter, Guido, Carrington, Mary, Franke, Andre, Bunders, Madeleine J, Schramm, Christoph, Altfeld, Marcus

Source: Gut; 2024, Vol. 73 Issue: 2 p325-337, 13p

Association Between Variants of PRDM1 and NDP52 and Crohn's Disease, Based on Exome Sequencing and Functional Studies

Authors: Ellinghaus, David, Zhang, Hu, Zeissig, Sebastian, Lipinski, Simone, Till, Andreas, Jiang, Tao, Stade, Björn, Bromberg, Yana, Ellinghaus, Eva, Keller, Andreas, Rivas, Manuel A., Skieceviciene, Jurgita, Doncheva, Nadezhda T., Liu, Xiao, Liu, Qing, Jiang, Fuman, Forster, Michael, Mayr, Gabriele, Albrecht, Mario, Häsler, Robert, Boehm, Bernhard O., Goodall, Jane, Berzuini, Carlo R., Lee, James, Andersen, Vibeke, Vogel, Ulla, Kupcinskas, Limas, Kayser, Manfred, Krawczak, Michael, Nikolaus, Susanna, Weersma, Rinse K., Ponsioen, Cyriel Y., Sans, Miquel, Wijmenga, Cisca, Strachan, David P., McArdle, Wendy L., Vermeire, Séverine, Rutgeerts, Paul, Sanderson, Jeremy D., Mathew, Christopher G., Vatn, Morten H., Wang, Jun, Nöthen, Markus M., Duerr, Richard H., Büning, Carsten, Brand, Stephan, Glas, Jürgen, Winkelmann, Juliane, Illig, Thomas, Latiano, Anna, Annese, Vito, Halfvarson, Jonas, D'Amato, Mauro, Daly, Mark J., Nothnagel, Michael, Karlsen, Tom H., Subramani, Suresh, Rosenstiel, Philip, Schreiber, Stefan, Parkes, Miles, Franke, Andre

Source: In Gastroenterology August 2013 145(2):339-347

Extended analysis of a genome-wide association study in primary sclerosing cholangitis detects multiple novel risk loci

Authors: Folseraas, Trine, Melum, Espen, Rausch, Philipp, Juran, Brian D., Ellinghaus, Eva, Shiryaev, Alexey, Laerdahl, Jon K., Ellinghaus, David, Schramm, Christoph, Weismüller, Tobias J., Gotthardt, Daniel Nils, Hov, Johannes Roksund, Clausen, Ole Petter, Weersma, Rinse K., Janse, Marcel, Boberg, Kirsten Muri, Björnsson, Einar, Marschall, Hanns-Ulrich, Cleynen, Isabelle, Rosenstiel, Philip, Holm, Kristian, Teufel, Andreas, Rust, Christian, Gieger, Christian, Wichmann, H-Erich, Bergquist, Annika, Ryu, Euijung, Ponsioen, Cyriel Y., Runz, Heiko, Sterneck, Martina, Vermeire, Severine, Beuers, Ulrich, Wijmenga, Cisca, Schrumpf, Erik, Manns, Michael P., Lazaridis, Konstantinos N., Schreiber, Stefan, Baines, John F., Franke, Andre, Karlsen, Tom H.

Source: In Journal of Hepatology August 2012 57(2):366-375

Combined Analysis of Genome-wide Association Studies for Crohn Disease and Psoriasis Identifies Seven Shared Susceptibility Loci

Authors: Ellinghaus, David, Ellinghaus, Eva, Nair, Rajan P., Stuart, Philip E., Esko, Tõnu, Metspalu, Andres, Debrus, Sophie, Raelson, John V., Tejasvi, Trilokraj, Belouchi, Majid, West, Sarah L., Barker, Jonathan N., Kõks, Sulev, Kingo, Külli, Balschun, Tobias, Palmieri, Orazio, Annese, Vito, Gieger, Christian, Wichmann, H. Erich, Kabesch, Michael, Trembath, Richard C., Mathew, Christopher G., Abecasis, Gonçalo R., Weidinger, Stephan, Nikolaus, Susanna, Schreiber, Stefan, Elder, James T., Weichenthal, Michael, Nothnagel, Michael, Franke, Andre

Source: In The American Journal of Human Genetics 6 April 2012 90(4):636-647

Genome-Wide Meta-Analysis of Psoriatic Arthritis Identifies Susceptibility Locus at REL

Authors: Ellinghaus, Eva ^*, Stuart, Philip E., Ellinghaus, David ^*, Nair, Rajan P., Debrus, Sophie, Raelson, John V., Belouchi, Majid, Tejasvi, Trilokraj, Li, Yanming, Tsoi, Lam C., Onken, Anna T., Esko, Tonu, Metspalu, Andres, Rahman, Proton, Gladman, Dafna D., Bowcock, Anne M., Helms, Cynthia, Krueger, Gerald G., Koks, Sulev, Kingo, Külli, Gieger, Christian, Erich Wichmann, H., Mrowietz, Ulrich, Weidinger, Stephan, Schreiber, Stefan, Abecasis, Gonçalo R., Elder, James T., Weichenthal, Michael, Franke, Andre

Source: In Journal of Investigative Dermatology April 2012 132(4):1133-1140