Effect of boswellic acids on the expression of PD-1 and TIGIT immune checkpoints on activated human T cells

Authors: Meyiah, Abdo ^a, Al-Harrasi, Ahmed ^b, Ur Rehman, Najeeb ^b, Elkord, Eyad ^{a, c, d, ⁎}

Source: In Fitoterapia March 2025 181

The colorectal cancer microenvironment: Preclinical progress in identifying targets for cancer therapy

Authors: Meyiah, Abdo ^a, Khan, Faez Iqbal ^a, Alfaki, Dia Aldeen ^b, Murshed, Khaled ^c, Raza, Afsheen ^d, Elkord, Eyad ^{a, d, e, ⁎}

Source: In Translational Oncology March 2025 53

Investigating the functional role of BUB1B in aflatoxin B1-associated hepatocarcinogenesis

Authors: Hamdy, Hayam ^{a, b}, Aly, Wafaa A. ^c, Elkord, Eyad ^{d, e, f, ⁎}

Source: In Toxicology June 2025 514

Temporal patterns of cancer burden in Asia, 1990–2019: a systematic examination for the Global Burden of Disease 2019 study

Authors: Sharma, Rajesh, Abbastabar, Hedayat, Abdulah, Deldar Morad, Abidi, Hassan, Abolhassani, Hassan, Abrehdari-Tafreshi, Zahra, Absalan, Abdorrahim, Ali, Hiwa Abubaker, Abu-Gharbieh, Eman, Acuna, Juan Manuel, Adib, Nasrin, Sakilah Adnani, Qorinah Estiningtyas, Aghaei, Abbas, Ahmad, Aqeel, Ahmad, Sajjad, Ahmadi, Ali, Ahmadi, Sepideh, Ahmed, Luai A., Ajami, Marjan, Al Hamad, Hanadi, Al Hasan, Syed Mahfuz, Alanezi, Fahad Mashhour, Saeed Al-Gheethi, Adel Ali, Al-Hanawi, Mohammed Khaled, Ali, Abid, Ali, Beriwan Abdulqadir, Alimohamadi, Yousef, Aljunid, Syed Mohamed, Ali Al-Maweri, Sadeq Ali, Alqahatni, Saleh A., AlQudah, Mohammad, Al-Raddadi, Rajaa M., Al-Tammemi, Ala'a B., Ansari-Moghaddam, Alireza, Anwar, Sumadi Lukman, Anwer, Razique, Aqeel, Muhammad, Arabloo, Jalal, Arab-Zozani, Morteza, Ariffin, Hany, Artaman, Al, Arulappan, Judie, Ashraf, Tahira, Askari, Elaheh, Athar, Mohammad, Wahbi Atout, Maha Moh'd, Azadnajafabad, Sina, Badar, Muhammad, Badiye, Ashish D., Baghcheghi, Nayereh, Bagherieh, Sara, Bai, Ruhai, Bajbouj, Khuloud, Baliga, Shrikala, Bardhan, Mainak, Bashiri, Azadeh, Baskaran, Pritish, Basu, Saurav, Belgaumi, Uzma Iqbal, Nazer C Bermudez, Amiel, Bhandari, Bharti, Bhardwaj, Nikha, Bhat, Ajay Nagesh, Bitaraf, Saeid, Boloor, Archith, Hashemi, Milad Bonakdar, Butt, Zahid A., Chadwick, Joshua, Kai Chan, Jeffrey Shi, Chattu, Vijay Kumar, Chaturvedi, Pankaj, Cho, William C.S., Darwesh, Aso Mohammad, Dash, Nihar Ranjan, Dehghan, Amin, Dhali, Arkadeep, Dianatinasab, Mostafa, Dibas, Mahmoud, Dixit, Abhinav, Dixit, Shilpi Gupta, Dorostkar, Fariba, Dsouza, Haneil Larson, Elbarazi, Iffat, Elemam, Noha Mousaad, El-Huneidi, Waseem, Elkord, Eyad, Abdou Elmeligy, Omar Abdelsadek, Emamian, Mohammad Hassan, Erkhembayar, Ryenchindorj, Ezzeddini, Rana, Fadoo, Zehra, Faiz, Razana, Fakhradiyev, Ildar Ravisovich, Fallahzadeh, Aida, Faris, MoezAlIslam Ezzat Mahmoud, Farrokhpour, Hossein, Fatehizadeh, Ali, Fattahi, Hamed, Fekadu, Ginenus, Fukumoto, Takeshi, Gaidhane, Abhay Motiramji, Galehdar, Nasrin, Garg, Priyanka, Ghadirian, Fataneh, Ghafourifard, Mansour, Ghasemi, MohammadReza, Nour, Mohammad Ghasemi, Ghassemi, Fariba, Gholamalizadeh, Maryam, Gholamian, Asadollah, Ghotbi, Elena, Golechha, Mahaveer, Goleij, Pouya, Goyal, Sahil, Mohialdeen Gubari, Mohammed Ibrahim, Gunasekera, D Sanjeeva, Gunawardane, Damitha Asanga, Gupta, Sapna, Habibzadeh, Parham, Haeri Boroojeni, Helia Sadat, Halboub, Esam S., Hamadeh, Randah R., Hamoudi, Rifat, Harorani, Mehdi, Hasanian, Mohammad, Hassan, Treska S., Hay, Simon I., Heidari, Mohammad, Heidari-Foroozan, Mahsa, Hessami, Kamran, Hezam, Kamal, Hiraike, Yuta, Holla, Ramesh, Hoseini, Mohammad, Hossain, Md Mahbub, Hossain, Sahadat, Hsieh, Vivian Chia-rong, Huang, Junjie, Hussein, Nawfal R., Hwang, Bing-Fang, Iravanpour, Farideh, Ismail, Nahlah Elkudssiah, Iwagami, Masao, Merin J, Linda, Jadidi-Niaragh, Farhad, Jafarinia, Morteza, Jahani, Mohammad Ali, Jahrami, Haitham, Jaiswal, Abhishek, Jakovljevic, Mihajlo, Jalili, Mahsa, Jamshidi, Elham, Jayarajah, Umesh, Jayaram, Shubha, Jha, Sweety Suman, Jokar, Mohammad, Joseph, Nitin, Kabir, Ali, Kabir, Md. Awal, Kadir, Dler Hussein, Kakodkar, Pradnya Vishal, Kalankesh, Laleh R., Kalankesh, Leila R., Kalhor, Rohollah, Kaliyadan, Feroze, Kamal, Vineet Kumar, Kamal, Zul, Kamath, Ashwin, Kar, Sitanshu Sekhar, Karimi, Hanie, Kaur, Navjot, Keikavoosi-Arani, Leila, Keykhaei, Mohammad, Khader, Yousef Saleh, Khajuria, Himanshu, Khan, Ejaz Ahmad, Khan, M Nuruzzaman, Khan, Maseer, Khan, Moien A.B., Khan, Yusra H., Khanmohammadi, Shaghayegh, Khatatbeh, Moawiah Mohammad, Khateri, Sorour, Khayamzadeh, Maryam, Khayat Kashani, Hamid Reza, Kim, Min Seo, Kompani, Farzad, Koohestani, Hamid Reza, Koulmane Laxminarayana, Sindhura Lakshmi, Krishan, Kewal, Kumar, Narinder, Kumar, Naveen, Kutluk, Tezer, Kuttikkattu, Ambily, Ching Lai, Daphne Teck, Lal, Dharmesh Kumar, Lami, Faris Hasan, Lasrado, Savita, Lee, Sang-Woong, Lee, Seung Won, Lee, Yeong Yeh, Lee, Yo Han, Leong, Elvynna, Li, Ming-Chieh, Liu, Jue, Madadizadeh, Farzan, Mafi, Ahmad R., Mahjoub, Soleiman, Malekzadeh, Reza, Malik, Ahmad Azam, Malik, Iram, Mallhi, Tauqeer Hussain, Mansournia, Mohammad Ali, Martini, Santi, Mathews, Elezebeth, Mathur, Manu Raj, Meena, Jitendra Kumar, Menezes, Ritesh G., Mirfakhraie, Reza, Mirinezhad, Seyed Kazem, Mirza-Aghazadeh-Attari, Mohammad, Mithra, Prasanna, Mohamadkhani, Ashraf, Mohammadi, Soheil, Mohammadzadeh, Maryam, Mohan, Syam, Mokdad, Ali H., Al Montasir, Ahmed, Montazeri, Fateme, Moradi, Maryam, Sarabi, Mostafa Moradi, Moradpour, Farhad, Moradzadeh, Maliheh, Moraga, Paula, Mosapour, Abbas, Motaghinejad, Majid, Mubarik, Sumaira, Muhammad, Jibran Sualeh, Murray, Christopher J.L., Nagarajan, Ahamarshan Jayaraman, Naghavi, Mohsen, Nargus, Shumaila, Natto, Zuhair S., Nayak, Biswa Prakash, Nejadghaderi, Seyed Aria, Nguyen, Phuong The, Niazi, Robina Khan, Noroozi, Nafise, Okati-Aliabad, Hassan, Okekunle, Akinkunmi Paul, Ong, Sokking, Oommen, Anu Mary, Padubidri, Jagadish Rao, Pandey, Ashok, Park, Eun-Kee, Park, Seoyeon, Pati, Siddhartha, Patil, Shankargouda, Paudel, Rajan, Paudel, Uttam, Pirestani, Majid, Podder, Indrashis, Pourali, Ghazaleh, Pourjafar, Mona, Pourshams, Akram, Syed, Zahiruddin Quazi, Radhakrishnan, Raghu Anekal, Radhakrishnan, Venkatraman, Rahman, Mosiur, Rahmani, Shayan, Rahmanian, Vahid, Ramesh, Pushkal Sinduvadi, Rana, Juwel, Rao, Indu Ramachandra, Rao, Sowmya J., Rashedi, Sina, Rashidi, Mohammad-Mahdi, Rezaei, Nazila, Rezaei, Negar, Rezaei, Nima, Rezaei, Saeid, Rezaeian, Mohsen, Roshandel, Gholamreza, Chandan, S.N., Saber-Ayad, Maha Mohamed, Sabour, Siamak, Sabzmakan, Leila, Saddik, Basema, Saeed, Umar, Safi, Sher Zaman, Sharif-Askari, Fatemeh Saheb, Sahebkar, Amirhossein, Sahoo, Harihar, Sajedi, Seyed Aidin, Sajid, Mirza Rizwan, Salehi, Mohammad Amin, Farrokhi, Amir Salek, Sarasmita, Made Ary, Sargazi, Saman, Sarode, Gargi Sachin, Sarode, Sachin C., Sathian, Brijesh, Satpathy, Maheswar, Semwal, Prabhakar, Senthilkumaran, Subramanian, Sepanlou, Sadaf G., Shafeghat, Melika, Shahabi, Saeed, Shahbandi, Ataollah, Shahraki-Sanavi, Fariba, Shaikh, Masood Ali, Shannawaz, Mohammed, Sheikhi, Rahim Ali, Shobeiri, Parnian, Shorofi, Seyed Afshin, Shrestha, Sunil, Siabani, Soraya, Singh, Garima, Singh, Paramdeep, Singh, Surjit, Sinha, Dhirendra Narain, Siwal, Samarjeet Singh, Sreeram, Saraswathy, Suleman, Muhammad, Abdulkader, Rizwan Suliankatchi, Sultan, Iyad, Sultana, Abida, Tabish, Mohammad, Tabuchi, Takahiro, Taheri, Majid, Talaat, Iman M., Tehrani-Banihashemi, Arash, Temsah, Mohamad-Hani, Thangaraju, Pugazhenthan, Thomas, Nihal, Thomas, Nikhil Kenny, Tiyuri, Amir, Tobe-Gai, Ruoyan, Toghroli, Razie, Tovani-Palone, Marcos Roberto, Ullah, Sana, Unnikrishnan, Bhaskaran, Upadhyay, Era, Tahbaz, Sahel Valadan, Valizadeh, Rohollah, Varthya, Shoban Babu, Waheed, Yasir, Wang, Song, Wickramasinghe, Dakshitha Praneeth, Wickramasinghe, Nuwan Darshana, Xiao, Hong, Yonemoto, Naohiro, Younis, Mustafa Z., Yu, Chuanhua, Zahir, Mazyar, Zaki, Nazar, Zamanian, Maryam, Zhang, Zhi-Jiang, Zhao, Hanqing, Zitoun, Osama A., Zoladl, Mohammad

Source: In The Lancet Regional Health - Southeast Asia February 2024 21

Effect of Boswellic acids on T cell proliferation and activation

Authors: Meyiah, Abdo ^a, Shawkat, Murtada Y. ^b, Ur Rehman, Najeeb ^a, Al-Harrasi, Ahmed ^{a, ⁎}, Elkord, Eyad ^{a, b, c, ⁎}

Source: In International Immunopharmacology September 2023 122

Co-expression of PD-1 with TIGIT or PD-1 with TIM-3 on tumor-infiltrating CD8+ T cells showed synergistic effects on improved disease-free survival in treatment-naïve CRC patients

Authors: Meyiah, Abdo, Mahmoodi Chalbatani, Ghanbar, Al-Mterin, Mohamed A., Malekraeisi, Mohammad Amin, Murshed, Khaled, Elkord, Eyad

Source: In International Immunopharmacology June 2023 119

Role of exosomal ncRNAs released by M2 macrophages in tumor progression of gastrointestinal cancers

Authors: Meyiah, Abdo ^{1, 4}, Alahdal, Murad ^{1, 4}, Elkord, Eyad ^{1, 2, 3, ∗}

Source: In iScience 21 April 2023 26(4)

The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)

Authors: Inchakalody, Varghese P., Hydrose, Shereena P., Krishnankutty, Roopesh, Merhi, Maysaloun, Therachiyil, Lubna, Sasidharan Nair, Varun, Elashi, Asma A., Khan, Abdul Q., Taleb, Sara, Raza, Afsheen, Yoosuf, Zeenath Safira K.M., Fernandes, Queenie, Al-Zaidan, Lobna, Mestiri, Sarra, Taib, Nassiba, Bedhiafi, Takwa, Moustafa, Dina, Assami, Laila, Maalej, Karama Makni, Elkord, Eyad, Uddin, Shahab, Al Homsi, Ussama, Dermime, Said

Source: In European Journal of Pharmacology 15 April 2023 945

Exhaustion and over-activation of immune cells in COVID-19: Challenges and therapeutic opportunities

Authors: Alahdal, Murad, Elkord, Eyad

Source: In Clinical Immunology December 2022 245

Exploring the Role of Cellular Interactions in the Colorectal Cancer Microenvironment.

Authors: Tang, Jiadai, Chen, Liuhan, Shen, Xin, Xia, Tingrong, Li, Zhengting, Chai, Xiaoying, Huang, Yao, Yang, Shaoqiong, Peng, Xinjun, Lai, Junbo, Li, Rui, Xie, Lin, Elkord, Eyad

Source: Journal of Immunology Research; 4/11/2025, Vol. 2025, p1-26, 26p

Cancer-associated fibroblasts in hepatocellular carcinoma: heterogeneity, mechanisms and therapeutic targets.

Authors: Li, Yutong, Hamad, Mawieh, Elkord, Eyad

Source: Hepatology International; Apr2025, Vol. 19 Issue 2, p325-336, 12p

Role of circular RNAs in colorectal tumor microenvironment

Authors: Viralippurath Ashraf, Jasni, Sasidharan Nair, Varun, Saleh, Reem, Elkord, Eyad

Source: In Biomedicine & Pharmacotherapy May 2021 137

Resistance mechanisms to immune checkpoint inhibitors: updated insights.

Authors: Alsaafeen, Besan H., Ali, Bassam R., Elkord, Eyad

Source: Molecular Cancer; 1/15/2025, Vol. 24 Issue 1, p1-20, 20p

Subject Terms: IMMUNE checkpoint inhibitors, IMMUNE system

Lymphocyte-activation gene 3 in cancer immunotherapy: function, prognostic biomarker and therapeutic potentials.

Authors: Ren, Ke, Hamdy, Hayam, Meyiah, Abdo, Elkord, Eyad

Source: Frontiers in Immunology; 2024, p1-12, 12p

Subject Terms: IMMUNE checkpoint proteins, T cells, SMALL molecules, LIGANDS (Biochemistry), IMMUNOSUPPRESSION

Turning Cancer Immunotherapy to the Emerging Immune Checkpoint TIGIT: Will This Break Through the Limitations of the Legacy Approach?

Authors: Cui, Haozhe, Elkord, Eyad

Source: Vaccines; Dec2024, Vol. 12 Issue 12, p1306, 10p

Subject Terms: IMMUNE checkpoint proteins, BISPECIFIC antibodies, IMMUNE checkpoint inhibitors, KILLER cells, CANCER vaccines

Effects of 1 H -1,2,3-Triazole Derivatives of 3- O -Acetyl-11-Keto-Beta-Boswellic Acid from Boswellia sacra Resin on T-Cell Proliferation and Activation.

Authors: Meyiah, Abdo, Avula, Satya Kumar, Al-Harrasi, Ahmed, Elkord, Eyad

Source: Pharmaceuticals (14248247); Dec2024, Vol. 17 Issue 12, p1650, 14p

Subject Terms: TRIAZOLE derivatives, NATURAL products, CD25 antigen, CELL survival, BOSWELLIA, T cells

An evaluation of sorter induced cell stress (SICS) on peripheral blood mononuclear cells (PBMCs) after different sort conditions - Are your sorted cells getting SICS?

Authors: Pfister, Gerald, Toor, Salman M., Sasidharan Nair, Varun, Elkord, Eyad

Source: In Journal of Immunological Methods December 2020 487

FoxP3+ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets

Authors: Saleh, Reem, Elkord, Eyad

Source: In Cancer Letters 10 October 2020 490:174-185

Immune checkpoints in the tumor microenvironment

Authors: Toor, Salman M., Sasidharan Nair, Varun, Decock, Julie, Elkord, Eyad ^*

Source: In Seminars in Cancer Biology October 2020 65:1-12

Acquired resistance to cancer immunotherapy: Role of tumor-mediated immunosuppression

Authors: Saleh, Reem, Elkord, Eyad

Source: In Seminars in Cancer Biology October 2020 65:13-27