IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection.

Authors: Gaia Muallem, Sagie Wagage, Yan Sun, Jonathan H DeLong, Alex Valenzuela, David A Christian, Gretchen Harms Pritchard, Qun Fang, Elizabeth L Buza, Deepika Jain, M Merle Elloso, Carolina B López, Christopher A Hunter

Source: PLoS Pathogens, Vol 13, Iss 1, p e1006173 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5305264?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

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The Group 3 Innate Lymphoid Cell Defect in Aryl Hydrocarbon Receptor Deficient Mice Is Associated with T Cell Hyperactivation during Intestinal Infection.

Authors: Sagie Wagage, Gretchen Harms Pritchard, Lucas Dawson, Elizabeth L Buza, Gregory F Sonnenberg, Christopher A Hunter

Source: PLoS ONE, Vol 10, Iss 5, p e0128335 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4444139?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/875322e40caa418db8ff7260b8590bc3

Lipid nanoparticle-encapsulated mRNA therapy corrects serum total bilirubin level in Crigler-Najjar syndrome mouse model

Authors: Jenny A. Greig, Joanna K. Chorazeczewski, Vivek Chowdhary, Melanie K. Smith, Matthew Jennis, James C. Tarrant, Elizabeth L. Buza, Kimberly Coughlan, Paolo G.V. Martini, James M. Wilson

Source: Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 32-39 (2023)

Subject Terms: Crigler-Najjar, lipid nanoparticle, LNP, mRNA, UGT1A1, hyperbilirubinemia, Genetics, QH426-470, Cytology, QH573-671

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Relation: http://www.sciencedirect.com/science/article/pii/S2329050123000177; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/4c4c351c175a4e80928fe2e172b5b2ec

Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors

Authors: Makoto Horiuchi, Christian J. Hinderer, Jenny A. Greig, Cecilia Dyer, Elizabeth L. Buza, Peter Bell, Jessica A. Chichester, Peter M. Hayashi, Hanying Yan, Tamara Goode, James M. Wilson

Source: Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 272-280 (2022)

Subject Terms: AAV, intrathecal, intravenous immunoglobulin, neutralizing antibodies, central nervous system, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122001425; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/47d10615a3624fa0872c118998bf302a

Prednisolone reduces the interferon response to AAV in cynomolgus macaques and may increase liver gene expression

Authors: Lili Wang, Claude C. Warzecha, Alexander Kistner, Jessica A. Chichester, Peter Bell, Elizabeth L. Buza, Zhenning He, M. Betina Pampena, Julien Couthouis, Sunjay Sethi, Kathleen McKeever, Michael R. Betts, Emil Kakkis, James M. Wilson, Samuel Wadsworth, Barbara A. Sullivan

Source: Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 292-305 (2022)

Subject Terms: adeno-associated virus, AAV8, ornithine transcarbamylase deficiency, non-human primates, sex, immunosuppression, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122000080; https://doaj.org/toc/2329-0501

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Immune transgene-dependent myocarditis in macaques after systemic administration of adeno-associated virus expressing human acid alpha-glucosidase

Authors: Juliette Hordeaux, Ali Ramezani, Steve Tuske, Nickita Mehta, Chunjuan Song, Anna Lynch, Katherine Lupino, Jessica A. Chichester, Elizabeth L. Buza, Cecilia Dyer, Hongwei Yu, Peter Bell, Jill M. Weimer, Hung Do, James M. Wilson

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: AAV, toxicity, cytotoxic, T cell, Pompe disease, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1094279/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/399a575278114cbda824ff19d97176ed

Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors

Authors: Makoto Horiuchi, Christian J. Hinderer, Jenny A. Greig, Cecilia Dyer, Elizabeth L. Buza, Peter Bell, Jessica A. Chichester, Peter M. Hayashi, Hanying Yan, Tamara Goode, James M. Wilson

Source: Molecular Therapy: Methods & Clinical Development, Vol 27, Iss , Pp 450-451 (2022)

Subject Terms: Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050122001607; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/9a826929cd644436bf39474706fdb122

Toxicology Study of Intra-Cisterna Magna Adeno-Associated Virus 9 Expressing Human Alpha-L-Iduronidase in Rhesus Macaques

Authors: Juliette Hordeaux, Christian Hinderer, Tamara Goode, Nathan Katz, Elizabeth L. Buza, Peter Bell, Roberto Calcedo, Laura K. Richman, James M. Wilson

Source: Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 79-88 (2018)

Subject Terms: Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050118300573; https://doaj.org/toc/2329-0501

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Toxicology Study of Intra-Cisterna Magna Adeno-Associated Virus 9 Expressing Iduronate-2-Sulfatase in Rhesus Macaques

Authors: Juliette Hordeaux, Christian Hinderer, Tamara Goode, Elizabeth L. Buza, Peter Bell, Roberto Calcedo, Laura K. Richman, James M. Wilson

Source: Molecular Therapy: Methods & Clinical Development, Vol 10, Iss , Pp 68-78 (2018)

Subject Terms: Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050118300585; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/5a204333500b4ac4af8e689cf632c042

Context-Dependent Effects of Amplified MAPK Signaling during Lung Adenocarcinoma Initiation and Progression

Authors: Michelle Cicchini, Elizabeth L. Buza, Kyra M. Sagal, A. Andrea Gudiel, Amy C. Durham, David M. Feldser

Source: Cell Reports, Vol 18, Iss 8, Pp 1958-1969 (2017)

Subject Terms: Kras, MAPK, p53, lung adenocarcinoma, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717301390; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/18253b216cca47dc9a2732008fcf0a29

Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation of Hhex in MiceSummary

Authors: Mark J. Ferreira, Lindsay B. McKenna, Jia Zhang, Maximilian Reichert, Basil Bakir, Elizabeth L. Buza, Emma E. Furth, Clifford W. Bogue, Anil K. Rustgi, Klaus H. Kaestner

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 5, Pp 550-569 (2015)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X15001095; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/13f8248f1d774c53929ed9a3b0f1912d