Essential role of proline synthesis and the one-carbon metabolism pathways for systemic virulence of Streptococcus pneumoniae

Authors: Elisa Ramos-Sevillano, Giuseppe Ercoli, Modupeh Betts, José Afonso Guerra-Assunção, Amy Iverson, Matthew Frank, Frederick Partridge, Stephanie W. Lo, Vitor E. Fernandes, Fauzy Nasher, Emma Wall, Brendan Wren, Stephen B. Gordon, Daniela M. Ferreira, Rob Heyderman, Jason Rosch, Jeremy S. Brown

Source: mBio, Vol 15, Iss 11 (2024)

Subject Terms: Streptococcus pneumoniae, proline synthesis, formate-tetrahydrofolate ligase, stringent response, virulence, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/4b77d1a40d1e45dfa28773b4ec014327

Strain Specific Variations in Acinetobacter baumannii Complement Sensitivity

Authors: Gathoni Kamuyu, Giuseppe Ercoli, Elisa Ramos-Sevillano, Sam Willcocks, Chidchamai Kewcharoenwong, Pattarachai Kiratisin, Peter W. Taylor, Brendan W. Wren, Ganjana Lertmemongkolchai, Richard A. Stabler, Jeremy S. Brown

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: complement resistance/sensitivity, Acinetobacter baumanniia, multi-drug resistance (MDR), virulence, Gram negative bacteria, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.853690/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/949fc8236b204396ba6ef7b8401504c7

Maintained partial protection against Streptococcus pneumoniae despite B‐cell depletion in mice vaccinated with a pneumococcal glycoconjugate vaccine

Authors: Giuseppe Ercoli, Elisa Ramos‐Sevillano, Emma Pearce, Sara Ragab, David Goldblatt, Gisbert Weckbecker, Jeremy S Brown

Source: Clinical & Translational Immunology, Vol 11, Iss 1, Pp n/a-n/a (2022)

Subject Terms: B‐cell depletion, CD20, immunity, Streptococcus pneumoniae, vaccination, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2050-0068

Access URL: https://doaj.org/article/44361b1c8e4d434ab9c3e34bd97c6843

Genome-wide association studies reveal the role of polymorphisms affecting factor H binding protein expression in host invasion by Neisseria meningitidis.

Authors: Sarah G Earle, Mariya Lobanovska, Hayley Lavender, Changyan Tang, Rachel M Exley, Elisa Ramos-Sevillano, Douglas F Browning, Vasiliki Kostiou, Odile B Harrison, Holly B Bratcher, Gabriele Varani, Christoph M Tang, Daniel J Wilson, Martin C J Maiden

Source: PLoS Pathogens, Vol 17, Iss 10, p e1009992 (2021)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/0b6f3dfc4de74b43a1339c59c7591f44

Prophages and satellite prophages are widespread in Streptococcus and may play a role in pneumococcal pathogenesis

Authors: Reza Rezaei Javan, Elisa Ramos-Sevillano, Asma Akter, Jeremy Brown, Angela B. Brueggemann

Source: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/f8ad0d9a144a429081aa2df04cd9add5

The Influence of B Cell Depletion Therapy on Naturally Acquired Immunity to Streptococcus pneumoniae

Authors: Giuseppe Ercoli, Elisa Ramos-Sevillano, Rie Nakajima, Rafael Ramiro de Assis, Algis Jasinskas, David Goldblatt, Philip Felgner, Gisbert Weckbecker, Jeremy Brown

Source: Frontiers in Immunology, Vol 11 (2021)

Subject Terms: Streptococcus pneumoniae, anti-protein antibody, colonization, B cell depletion, CD20, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.611661/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/254598317059450e979cd18bc29cd6e8

CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With Streptococcus pneumoniae Meningitis

Authors: Emma C. Wall, Philip Brownridge, Gavin Laing, Vanessa S. Terra, Veronica Mlozowa, Brigitte Denis, Mulinda Nyirenda, Theresa Allain, Elisa Ramos-Sevillano, Enitan Carrol, Andrea Collins, Stephen B. Gordon, David G. Lalloo, Brendan Wren, Robert Beynon, Robert S. Heyderman, Jeremy S. Brown

Source: Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)

Subject Terms: meningitis, HIV—human immunodeficiency virus, mortality, Streptococcus pneumoniae, cerebrospinal fluid, proteomics, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2020.603623/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/163e0ab026b9423982b15ade154fdfc2

Deletion of the Zinc Transporter Lipoprotein AdcAII Causes Hyperencapsulation of Streptococcus pneumoniae Associated with Distinct Alleles of the Type I Restriction-Modification System

Authors: Claire Durmort, Giuseppe Ercoli, Elisa Ramos-Sevillano, Suneeta Chimalapati, Richard D. Haigh, Megan De Ste Croix, Katherine Gould, Jason Hinds, Yann Guerardel, Thierry Vernet, Marco Oggioni, Jeremy S. Brown

Source: mBio, Vol 11, Iss 2 (2020)

Subject Terms: Streptococcus pneumoniae, capsule expression, virulence, AdcAII, restriction modification, SpnD39III, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/3c6b97acfd444f4693bf02410dff2bee

Protective Effect of Nasal Colonisation with ∆cps/piaA and ∆cps/proABCStreptococcus pneumoniae Strains against Recolonisation and Invasive Infection

Authors: Elisa Ramos-Sevillano, Giuseppe Ercoli, José Afonso Guerra-Assunção, Philip Felgner, Rafael Ramiro de Assis, Rie Nakajima, David Goldblatt, Kevin Kweku Adjei Tetteh, Robert Simon Heyderman, Stephen Brian Gordon, Daniela Mulari Ferreria, Jeremy Stuart Brown

Source: Vaccines, Vol 9, Iss 3, p 261 (2021)

Subject Terms: Streptococcus pneumoniae, capsule, vaccine, psaA, proABC, colonisation, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-393X/9/3/261; https://doaj.org/toc/2076-393X

Access URL: https://doaj.org/article/49a7fad3616a46729a4e6aada6193bc7

Mechanisms of Naturally Acquired Immunity to Streptococcus pneumoniae

Authors: Elisa Ramos-Sevillano, Giuseppe Ercoli, Jeremy S. Brown

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: immunity, pneumococcus (Streptococcus pneumoniae), natural acquired immunity, pneumonia, protection, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.00358/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/4dd5b138a5d949778fb19d85ced81267

PSGL-1 on Leukocytes is a Critical Component of the Host Immune Response against Invasive Pneumococcal Disease.

Authors: Elisa Ramos-Sevillano, Ana Urzainqui, Belén de Andrés, Rafael González-Tajuelo, Mirian Domenech, Fernando González-Camacho, Francisco Sánchez-Madrid, Jeremy S Brown, Ernesto García, Jose Yuste

Source: PLoS Pathogens, Vol 12, Iss 3, p e1005500 (2016)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1005500&type=printable; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/e17c4aab58d440748c6b19695e18efa9

Cefditoren and ceftriaxone enhance complement-mediated immunity in the presence of specific antibodies against antibiotic-resistant pneumococcal strains.

Authors: Elisa Ramos-Sevillano, Cinthya Rodríguez-Sosa, Fabio Cafini, Maria-Jose Giménez, Ana Navarro, David Sevillano, Luis Alou, Ernesto García, Lorenzo Aguilar, Jose Yuste

Source: PLoS ONE, Vol 7, Iss 9, p e44135 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3434200?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1f4cfdb19c604a858d6efc450dba5433

Nasopharyngeal colonization and invasive disease are enhanced by the cell wall hydrolases LytB and LytC of Streptococcus pneumoniae.

Authors: Elisa Ramos-Sevillano, Miriam Moscoso, Pedro García, Ernesto García, Jose Yuste

Source: PLoS ONE, Vol 6, Iss 8, p e23626 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3160309?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/0873ea9b37ad43459ffe82721edbe834

Enhanced in vivo activity of cefditoren in pre-immunized mice against penicillin-resistant S. pneumoniae (serotypes 6B, 19F and 23F) in a sepsis model.

Authors: Fabio Cafini, Jose Yuste, Maria-Jose Giménez, David Sevillano, Lorenzo Aguilar, Luis Alou, Elisa Ramos-Sevillano, Martha Torrico, Natalia González, Ernesto García, Pilar Coronel, Jose Prieto

Source: PLoS ONE, Vol 5, Iss 8, p e12041 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2919394?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/c483512b87be44678a276314c76ecf4a