Nicotinamide metabolism reprogramming drives reversible senescence of glioblastoma cells.

Authors: Narayanan, Ashwin, Saurty-Seerunghen, Mirca S., Michieletto, Jessica, Delaunay, Virgile, Bruneel, Arnaud, Dupré, Thierry, Ottolenghi, Chris, Pontoizeau, Clément, Ciccone, Lucrezia, De La Vara, Andreas, Idbaih, Ahmed, Turchi, Laurent, Virolle, Thierry, Chneiweiss, Hervé, Junier, Marie-Pierre, El-Habr, Elias A.

Source: Cellular & Molecular Life Sciences; 3/21/2025, Vol. 82 Issue 1, p1-15, 15p

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

Authors: Martínez-Vélez, Naiara, Garcia-Moure, Marc, Marigil, Miguel, González-Huarriz, Marisol, Puigdelloses, Montse, Gallego Pérez-Larraya, Jaime, Zalacaín, Marta, Marrodán, Lucía, Varela-Guruceaga, Maider, Laspidea, Virginia, Aristu, Jose, Ramos, Luis, Tejada-Solís, Sonia, Díez-Valle, Ricardo, Jones, Chris, Mackay, Alan, Martínez-Climent, Jose, García-Barchino, Maria, Raabe, Eric, Monje, Michelle, Becher, Oren, Junier, Marie, El-Habr, Elias, Chneiweiss, Herve, Aldave, Guillermo, Jiang, Hong, Fueyo, Juan, Patiño-García, Ana, Gomez-Manzano, Candelaria, Alonso, Marta

Source: Nature communications. 10(1):1-10

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100153445220.0x000001&indx=1&recIds=ETOCvdc_100153445220.0x000001

Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling

Authors: Dong, Jihu, Aulestia, Francisco J., Assad Kahn, Suzana, Zeniou, Maria, Dubois, Luiz Gustavo, El-Habr, Elias A., Daubeuf, François, Tounsi, Nassera, Cheshier, Samuel H., Frossard, Nelly, Junier, Marie-Pierre, Chneiweiss, Hervé, Néant, Isabelle, Moreau, Marc, Leclerc, Catherine, Haiech, Jacques, Kilhoffer, Marie-Claude

Source: In BBA - Molecular Cell Research June 2017 1864(6):1018-1027

Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation

Authors: Lesueur, Paul, Chevalier, François, El-Habr, Elias, Junier, Marie-Pierre, Chneiweiss, Hervé, Castera, Laurent, Müller, Etienne, Stefan, Dinu, Saintigny, Yannick

Source: Scientific reports. 8(1):1-12

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117621437.0x000001&indx=1&recIds=ETOCvdc_100117621437.0x000001

Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness

Authors: Bogeas, Alexandra, Morvan-Dubois, Ghislaine, El-Habr, Elias A., Lejeune, François-Xavier, Defrance, Matthieu, Narayanan, Ashwin, Kuranda, Klaudia, Burel-Vandenbos, Fanny, Sayd, Salwa, Delaunay, Virgile, Dubois, Luiz G., Parrinello, Hugues, Rialle, Stéphanie, Fabrega, Sylvie, Idbaih, Ahmed, Haiech, Jacques, Bièche, Ivan, Virolle, Thierry, Goodhardt, Michele, Chneiweiss, Hervé, Junier, Marie-Pierre

Source: Acta neuropathologica. 135(2):267-283

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100141526234.0x000001&indx=1&recIds=ETOCvdc_100141526234.0x000001

Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1, 4, 5-triphosphate receptor dependent calcium signaling

Authors: Dong, Jihu, Aulestia, Francisco J., Assad Kahn, Suzana, Zeniou, Maria, Dubois, Luiz Gustavo, El-Habr, Elias A., Daubeuf, François, Tounsi, Nassera, Cheshier, Samuel H., Frossard, Nelly, Junier, Marie-Pierre, Chneiweiss, Hervé, Néant, Isabelle, Moreau, Marc, Leclerc, Catherine, Haiech, Jacques, Kilhoffer, Marie-Claude

Source: Biochimica et biophysica acta. 1864(6):1018-1027

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100044527955.0x000001&indx=1&recIds=ETOCvdc_100044527955.0x000001

Emergence of the cell-matrix adhesion element ILK as a player in glioblastoma cell plasticity.

Authors: Junier, Marie-Pierre¹ (AUTHOR) marie-pierre.junier@inserm.fr, El-Habr, Elias A.¹ (AUTHOR)

Source: Developmental Cell. Dec2024, Vol. 59 Issue 24, p3189-3190. 2p.

Subject Terms: *CELL-matrix adhesions, *GLIOBLASTOMA multiforme

Capture at the single cell level of metabolic modules distinguishing aggressive and indolent glioblastoma cells

Authors: Saurty-Seerunghen, Mirca S., Bellenger, Léa, El-Habr, Elias A., Delaunay, Virgile, Garnier, Delphine, Chneiweiss, Hervé, Antoniewski, Christophe, Morvan-Dubois, Ghislaine, Junier, Marie-Pierre

Source: Acta neuropathologica communications. 7(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130968676.0x000001&indx=1&recIds=ETOCvdc_100130968676.0x000001

Glioma Cells Expressing High Levels of ALDH5A1 Exhibit Enhanced Migration Transcriptional Signature in Patient Tumors.

Authors: Piperi, Christina, Saurty-Seerunghen, Mirca S., Levidou, Georgia, Sepsa, Athanasia, Trigka, Eleni-Andriana, Klonou, Alexia, Markouli, Mariam, Strepkos, Dimitrios, Spyropoulou, Anastasia, Kanakoglou, Dimitrios S., Lakiotaki, Eleftheria, Karatrasoglou, Eleni A., Boviatsis, Efstathios, El-Habr, Elias A., Korkolopoulou, Penelope

Source: Neurotherapeutics; Apr2023, Vol. 20 Issue 3, p881-895, 15p

Expression of nuclear factor- κB in human astrocytomas: relation to pI κBa, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival

Authors: Korkolopoulou, Penelope, Levidou, Georgia, Saetta, Angelica A., El-Habr, Elias, Eftichiadis, Christos, Demenagas, Polychronis, Thymara, Irene, Xiromeritis, Konstantinos, Boviatsis, Efstathios, Thomas-Tsagli, Euphemia, Panayotidis, Ioannis, Patsouris, Efstratios

Source: In Human Pathology 2008 39(8):1143-1152

Glioblastoma cell motility depends on enhanced oxidative stress coupled with mobilization of a sulfurtransferase.

Authors: Saurty-Seerunghen, Mirca S., Daubon, Thomas, Bellenger, Léa, Delaunay, Virgile, Castro, Gloria, Guyon, Joris, Rezk, Ahmed, Fabrega, Sylvie, Idbaih, Ahmed, Almairac, Fabien, Burel-Vandenbos, Fanny, Turchi, Laurent, Duplus, Eric, Virolle, Thierry, Peyrin, Jean-Michel, Antoniewski, Christophe, Chneiweiss, Hervé, El-Habr, Elias A., Junier, Marie-Pierre

Source: Cell Death & Disease; Oct2022, Vol. 13 Issue 10, p1-12, 12p

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The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway.

Authors: Assad Kahn, Suzana, Costa, Silvia Lima, Gholamin, Sharareh, Nitta, Ryan T, Dubois, Luiz Gustavo, Fève, Marie, Zeniou, Maria, Coelho, Paulo Lucas Cerqueira, El‐Habr, Elias, Cadusseau, Josette, Varlet, Pascale, Mitra, Siddhartha S, Devaux, Bertrand, Kilhoffer, Marie‐Claude, Cheshier, Samuel H, Moura‐Neto, Vivaldo, Haiech, Jacques, Junier, Marie‐Pierre, Chneiweiss, Hervé

Source: EMBO Molecular Medicine; May2016, Vol. 8 Issue 5, p511-526, 16p

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