In vivo measurements of change in tissue oxygen level during irradiation reveal novel dose rate dependence

Authors: Grilj, Veljko, Leavitt, Ron J., El Khatib, Mirna, Paisley, Ryan, Franco-Perez, Javier, Petit, Benoit, Ballesteros-Zebadua, Paola, Vozenin, Marie-Catherine

Source: In Radiotherapy and Oncology December 2024 201

Ultrafast Tracking of Oxygen Dynamics During Proton FLASH

Authors: El Khatib, Mirna, Van Slyke, Alexander L., Velalopoulou, Anastasia, Kim, Michele M., Shoniyozov, Khayrullo, Allu, Srinivasa Rao, Diffenderfer, Eric S., Busch, Theresa M., Wiersma, Rodney D., Koch, Cameron J., Vinogradov, Sergei A.

Source: International journal of radiation oncology, biology, physics. 113(3):624-634

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Spatiotemporal blood vessel specification at the osteogenesis and angiogenesis interface of biomimetic nanofiber-enabled bone tissue engineering

Authors: Zhai, Yuankun, Schilling, Kevin, Wang, Tao, El Khatib, Mirna, Vinogradov, Sergei, Brown, Edward B., Zhang, Xinping

Source: In Biomaterials September 2021 276

Photoinduced 1, 2-dicarbofunctionalization of alkenes with organotrifluoroborate nucleophiles via radical/polar crossoverElectronic supplementary information (ESI) available: Experimental and mechanistic studies details, as well as spectral data. See DOI: 10.1039/d1sc02547c

Authors: Cabrera-Afonso, María Jesús, Sookezian, Anasheh, Badir, Shorouk O., El Khatib, Mirna, Molander, Gary A.

Source: Chemical science. 12(26):9189-9195

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In vivo deep-tissue microscopy with UCNP/Janus-dendrimers as imaging probes: resolution at depth and feasibility of ratiometric sensingElectronic supplementary information (ESI) available: Additional experimental details, synthesis, optical spectroscopic data, materials characterization. See DOI: 10.1039/c9nr07778b

Authors: Plunkett, Shane, El Khatib, Mirna, Şencan, İkbal, Porter, Jason E., Kumar, Anand T. N., Collins, Joshua E., Sakadžić, Sava, Vinogradov, Sergei A.

Source: Nanoscale. 12(4):2657-2672

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Merger of dynamic two-photon and phosphorescence lifetime microscopy reveals dependence of lymphocyte motility on oxygen in solid and hematological tumors

Authors: Rytelewski, Mateusz, Haryutyunan, Karine, Nwajei, Felix, Shanmugasundaram, Meenakshi, Wspanialy, Patrick, Zal, M., Chen, Chao-Hsien, El Khatib, Mirna, Plunkett, Shane, Vinogradov, Sergei, Konopleva, Marina, Zal, Tomasz

Source: Journal for immunotherapy of cancer. 7(1):1-13

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Direct Measurements of FLASH-Induced Changes in Intracellular Oxygenation.

Authors: El Khatib, Mirna^1,2 (AUTHOR) elmirna@pennmedicine.upenn.edu, Motlagh, Azar O.³ (AUTHOR), Beyer, Jenna N.¹ (AUTHOR), Troxler, Thomas^1,2 (AUTHOR), Allu, Srinivasa Rao^1,2 (AUTHOR), Sun, Qi^1,2 (AUTHOR), Burslem, George M.¹ (AUTHOR), Vinogradov, Sergei A.^1,2 (AUTHOR) vinograd.upenn@gmail.com

Source: International Journal of Radiation Oncology, Biology, Physics. Mar2024, Vol. 118 Issue 3, p781-789. 9p.

Subject Terms: *OXYGEN in the blood, *PHOSPHORESCENCE, *RADIOTHERAPY, *ELECTROPORATION

Microwave-Assisted Regiospecific Synthesis of Pseudohalohydrin Esters

Authors: El Khatib, Mirna, Elagawany, Mohamed, Todadze, Ekaterina, Khelashvili, Levan, El-Feky, Said, Katritzky, Alan

Source: Synlett. 23(9):1384-1388

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Quinoxalino[2,3-c]cinnolines and Their 5-N-Oxide: Alkoxylation of Methyl-Substituted Quinoxalino[2,3-c]cinnolines to Acetals and Orthoesters.

Authors: Haddadin, Makhluf J., El-Khatib, Mirna, Shoker, Tharallah A.

Source: Journal of Organic Chemistry; October 21 2011, Vol. 76 Issue 20, p8421-8427, 7p

Benzotriazol-1-yl-sulfonyI Azide for Diazotransfer and Preparation of Azidoacylbenzotriazoles.

Authors: Katritzky, Alan R., El Khatib, Mirna, Bol'shakov, Oleg

Source: Journal of Organic Chemistry; October 1 2010, Vol. 75 Issue 19, p6532-6539, 8p

Unusual Reactivity and Metal Affinity of Water-Soluble Dipyrrins

Authors: El Khatib, Mirna, Cheprakov, Andrei V., Vinogradov, Sergei A.

Source: Inorganic Chemistry; August 2022, Vol. 61 Issue: 32 p12746-12758, 13p

Photoinduced 1,2-dicarbofunctionalization of alkenes with organotrifluoroborate nucleophiles via radical/polar crossover.

Authors: Cabrera-Afonso, María Jesús, Sookezian, Anasheh, Badir, Shorouk O., El Khatib, Mirna, Molander, Gary A.

Source: Chemical Science; 7/14/2021, Vol. 12 Issue 26, p9189-9195, 7p

Inhibition of Oxidative Phosphorylation Reverses Bone Marrow Hypoxia Visualized in Imageable Syngeneic B-ALL Mouse Model.

Authors: Rytelewski, Mateusz, Harutyunyan, Karine, Baran, Natalia, Mallampati, Saradhi, Zal, M. Anna, Cavazos, Antonio, Butler, Jason M., Konoplev, Sergej, El Khatib, Mirna, Plunkett, Shane, Marszalek, Joseph R., Andreeff, Michael, Zal, Tomasz, Konopleva, Marina

Source: Frontiers in Oncology; 6/30/2020, p1-15, 15p

Subject Terms: OXIDATIVE phosphorylation, BONE marrow, HYPOXEMIA, ACUTE leukemia, OXYGEN consumption

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Electrospun Fiber Mesh for High-Resolution Measurements of Oxygen Tension in Cranial Bone Defect Repair.

Authors: Schilling, Kevin, El Khatib, Mirna, Plunkett, Shane, Xue, Jiajia, Xia, Younan, Vinogradov, Sergei A., Brown, Edward, Zhang, Xinping

Source: ACS Applied Materials & Interfaces; 9/18/2019, Vol. 11 Issue 37, p33548-33558, 11p

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α-Arylation/Heteroarylation of Chiral α-Aminomethyltrifluoroborates by Synergistic Iridium Photoredox/Nickel Cross-Coupling Catalysis.

Authors: El Khatib, Mirna¹, Serafim, Ricardo Augusto Massarico^1,2, Molander, Gary A.¹, gmolandr@sas.upenn.edu

Source: Angewandte Chemie; 1/4/2016, Vol. 128 Issue 1, p262-266, 5p