A lentiviral vector B cell gene therapy platform for the delivery of the anti-HIV-1 eCD4-Ig-knob-in-hole-reversed immunoadhesin

Authors: Eirini Vamva, Stosh Ozog, Daniel P. Leaman, Rene Yu-Hong Cheng, Nicholas J. Irons, Andee Ott, Claire Stoffers, Iram Khan, Geraldine K.E. Goebrecht, Matthew R. Gardner, Michael Farzan, David J. Rawlings, Michael B. Zwick, Richard G. James, Bruce E. Torbett

Source: Molecular Therapy: Methods & Clinical Development, Vol 28, Iss , Pp 366-384 (2023)

Subject Terms: HIV-1 neutralization, lentiviral, immunoadhesin, eCD4-Ig, protein engineering, hematopoietic, Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050123000141; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/5335a8f9645a42be9c9d7d049a240b62

Development of a Novel Competitive qRT-PCR Assay to Measure Relative Lentiviral Packaging Efficiency

Authors: Eirini Vamva, Andrew M.L. Lever, Conrad A. Vink, Julia C. Kenyon

Source: Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 307-319 (2020)

Subject Terms: Genetics, QH426-470, Cytology, QH573-671

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2329050120301959; https://doaj.org/toc/2329-0501

Access URL: https://doaj.org/article/361803ffb87746f49f87ccee3b8b8885

An optimized measles virus glycoprotein-pseudotyped lentiviral vector production system to promote efficient transduction of human primary B cells

Authors: Eirini Vamva, Stosh Ozog, Els Verhoeyen, Richard G. James, David J. Rawlings, Bruce E. Torbett

Source: STAR Protocols, Vol 3, Iss 1, Pp 101228- (2022)

Subject Terms: Cell isolation, Flow Cytometry/Mass Cytometry, Immunology, Microbiology, Molecular Biology, Biotechnology and bioengineering, Science (General), Q1-390

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666166722001083; https://doaj.org/toc/2666-1667

Access URL: https://doaj.org/article/e6b7e6a73833410aad10f86653494eaf