Electron microscopy reveals that phospholipase C and Ca2+ signaling regulate keratin filament uncoupling from desmosomes in Pemphigus

Authors: Egu, Desalegn T., Schmitt, Thomas, Sigmund, Anna M., Waschke, Jens

Source: In Annals of Anatomy April 2022 241

Cholinergic signaling impairs cardiomyocyte cohesion

Authors: Yeruva, Sunil, Körber, Lars, Hiermaier, Matthias, Egu, Desalegn T., Kempf, Ellen, Waschke, Jens

Source: Acta physiologica. 236(3)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163524684.0x000001&indx=1&recIds=ETOCvdc_100163524684.0x000001

Apremilast prevents blistering in human epidermis and stabilizes keratinocyte adhesion in pemphigus.

Authors: Sigmund, Anna M., Winkler, Markus, Engelmayer, Sophia, Kugelmann, Daniela, Egu, Desalegn T., Steinert, Letyfee S., Fuchs, Michael, Hiermair, Matthias, Radeva, Mariya Y., Bayerbach, Franziska C., Butz, Elisabeth, Kotschi, Stefan, Hudemann, Christoph, Hertl, Michael, Yeruva, Sunil, Schmidt, Enno, Yazdi, Amir S., Ghoreschi, Kamran, Vielmuth, Franziska, Waschke, Jens

Source: Nature Communications; 1/9/2023, Vol. 14 Issue 1, p1-17, 17p

Subject Terms: APREMILAST, PHOSPHODIESTERASE inhibitors, KERATINOCYTE differentiation, PEMPHIGUS, AUTOANTIBODIES, EPIDERMIS, KERATINOCYTES, PEMPHIGUS vulgaris

Role of ADAM10 and ADAM17 in the Regulation of Keratinocyte Adhesion in Pemphigus Vulgaris.

Authors: Kugelmann, Daniela, Anders, Maresa, Sigmund, Anna M., Egu, Desalegn T., Eichkorn, Ramona A., Yazdi, Amir S., Sárdy, Miklós, Hertl, Michael, Didona, Dario, Hashimoto, Takashi, Waschke, Jens

Source: Frontiers in Immunology; 6/30/2022, Vol. 13, p1-8, 8p

Subject Terms: PEMPHIGUS vulgaris, KERATINOCYTES, CELL adhesion, AUTOANTIBODIES, MONOCLONAL antibodies, PEMPHIGUS

Dsg2 Upregulation as a Rescue Mechanism in Pemphigus

Authors: Sigmund, Anna M., Egu, Desalegn T., Waschke, Jens, Vielmuth, Franziska

Source: FASEB journal. 34(S1):1-1

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100140399882.0x000001&indx=1&recIds=ETOCvdc_100140399882.0x000001

Author Correction: Apremilast prevents blistering in human epidermis and stabilizes keratinocyte adhesion in pemphigus.

Authors: Sigmund, Anna M., Winkler, Markus, Engelmayer, Sophia, Kugelmann, Daniela, Egu, Desalegn T., Steinert, Letyfee S., Fuchs, Michael, Hiermaier, Matthias, Radeva, Mariya Y., Bayerbach, Franziska C., Butz, Elisabeth, Kotschi, Stefan, Hudemann, Christoph, Hertl, Michael, Yeruva, Sunil, Schmidt, Enno, Yazdi, Amir S., Ghoreschi, Kamran, Vielmuth, Franziska, Waschke, Jens

Source: Nature Communications; 2/7/2023, Vol. 14 Issue 1, p1-1, 1p

Subject Terms: APREMILAST, PEMPHIGUS, KERATINOCYTES, EPIDERMIS, ADHESION